Conserved Protein Domain Family
Sororin

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pfam09666: Sororin 
Sororin protein
Sororin is an essential, cell cycle-dependent mediator of sister chromatid cohesion. The protein is nuclear in interphase cells, dispersed from the chromatin in mitosis, and interacts with the cohesin complex.
Statistics
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PSSM-Id: 401560
Aligned: 9 rows
Threshold Bit Score: 86.8749
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002001522        566 ENVP-----PSAAATETstgpQSLTTIEPVDNNENVTNLVQLPNPRRALKYRSPLKDINILDVVVLPSWKKNVQQKNn-- 638
WGS:AANI:GJ14448-PB 488 ENMP-----PPAAAVAQ----ATPIKPSEDQENENFENYVQLPNPRRTLQHRSPLKDINILEVVVLPSWKKNAQPDK--- 555
XP_001993831        331 ENVP-----PAKETIVel--pMTSMVPSEGQENENLENFVQLPNPRRTLQHRSPLKDINILEVVMLPSWKKNV-PDPk-- 400
XP_002070529        338 ENMP-----P----------------VATPAGNENMENLVHLPNPRRTLQNRMPLKDINILEVVHLPPWKKNPLGQAtpl 396
XP_002031849        309 ENRP-----PPTIS--------KSMSINDQESEENAENFVHLPNPRRTLQKRTPFKDINILEVVTLPSWKKNVTTNVsk- 374
Q9CPY3               88 ENNP-----PLKVP-TKedlfKTCSVPGTPSSTPVLYTQNVEPDSGEAELDS---RDLEMSQKVRRSYSRLQSL------ 152 house mouse
NP_001094417         74 ENVErisevSTKRSKVLtsspAISAEPKTSVLSPILPSSSPPPQPTESE------QDSVWSKKVRRSYSRLSMGDKSfe- 146
OCA37268             91 ENAI-----SEKSQMVPkeatSKPSAPEIDVLSPIPVNIQMSSNQDN--------RDIVMSQKVRRSYSRLEMSLNSssf 157
XP_001965923        410 ENVP-----PPITNTS-----QVSSYQVNDTSAEDVENYVHLPNPRRTLQKRTPFKDINILDVVVLPSWKKNVQTTPsk- 478
XP_002001522        639 ---TPTKESLssnqqqefnsnipgqqtsknptkesqtryeqQELNSYSPEHQcard--------kqeQQRQGCDLFGFED 707
WGS:AANI:GJ14448-PB 556 ---TPTKVSTar---------------------------nqNNVTISSPRQQsg------------rAQQSSSNLFGFED 593
XP_001993831        401 ---TPTRESMvrnq-----------------------vhfeHSIENISPGNLssrp--------allQRQKNSNLFGFED 446
XP_002070529        397 kdeSALRDAI-------------------------------SPITQRSSSDH---------------SRRESRNLFGFEE 430
XP_002031849        375 -evTPTRVAP-------------------------------RPMATSSPAQ----------------RSQTRSNLFGFDD 406
Q9CPY3              153 -----------------------------------------GCASTSTP---------------------GRRSFFGFEG 170 house mouse
NP_001094417        147 ---------------------------------------spRPARSSSPN--------------------NRESLFGFER 167
OCA37268            158 -lySPTRKT--------------------------------DSSDTSTPNAV---------------PKSGRRSLFGFDK 189
XP_001965923        479 -evTPSRQSQsta--------------------------ieRATVQASPSRTqtrvnlfgspnekspRQTEKRNLFGFEE 531
XP_002001522        708 FLSEEDEicvRepNQSVTKSCTDTTLHEKLQ--------RLKNLRP-------AQQELPQVSQAPMRH 760
WGS:AANI:GJ14448-PB 594 FLDEEDE---E--IANARAASQNVTLHEKLQ--------RLKDLRP-------ANEKLPQINREPLRH 641
XP_001993831        447 FLDDDDE---Q--PTSSHGQNQDVTLYEKLQ--------RLNRLRP-------ADKELPQVSKTPMHY 494
XP_002070529        431 FLDPNEH---SqhEVQATALSQDQTLNDKLQ--------RMKRLRP-------VDRDFPQVASTPLRY 480
XP_002031849        407 DLACEDI---L--TKSTTPSKGIAATSVSFN--------REVTPAL-------ANRSQMEVNTSECNE 454
Q9CPY3              171 ---PDD-------LPGVSPVVCSKLIETPKVpakdlvpaRTKDLVPdstkdlvPARTLPGISPPVVKE 228 house mouse
NP_001094417        168 LQTPEVM---KktEGSRSAPLGFMSLSLGSF--------NLSAADEsasnppeVDPNIPGV--CLGKK 222
OCA37268            190 LLNSEMP---EgeLRKSGSGTREKTANEKTLg-------TILPEEP--------DHNIPGV--VLAKQ 237
XP_001965923        532 FLNDSVA---A--TDRSPSRSQDVTLHDKLQ--------RLAELRP---------SNLPQVSSSPLRR 577
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