Conserved Protein Domain Family
MecR1

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COG4219: MecR1 
Signal transducer regulating beta-lactamase production, contains metallopeptidase domain [Signal transduction mechanisms]
Statistics
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PSSM-Id: 443363
Aligned: 462 rows
Threshold Bit Score: 120.541
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_114591738 111 YV-AVASFLLLRRGLSHLAIRMYVRGAVPCddpAVIASVRRIASKLGLTSPSLLLIPDCPGGAFTTGLRHPVVCVDPDLv 189
AHB40130      67 VVgTGLLSFLVQLIKTHIFLKKLLVK--KI---PVSRVLAGVLEKLKLTKKVVLVKDDNLFS-FCCGIFSPFIVVSTGLv 140
WP_013064115 104 FI-IGVLCRLFFIANSYRLLRRIISDSEQH------TLEDD----------VTLAVVDLPVAPFSW---MRTIVLSRID- 162
WP_013065113  97 YL-VGVVLKLLHTAISIYRLNKLINQCEQH------PQADG----------TTIAVCAQNIAPFSW---WNTIVFSRRD- 155
WP_041620386 128 YI-AVTAVLFVLLFVQFFKILGLKRRGRLT-------TKDG----------FEVIESDEIPTPFSF---YKTIFLSPNL- 185
WP_014774569  99 YL-LGAVLIAGVMAWQVFRIHRLRRGAEIS------RT-GD----------YTLVRTRQEIASFSF---LRTIYVWDK-- 155
WP_038654844  93 YL-IGVGVMTLWLMIGAIKIFLTISKGKVE------RI-EE----------LRVIFAQQRLSAYSV---FSYIFINKAL- 150
WP_045089423  99 LL-SGALFFLCRYIIGLIQIIKIIQGSEKH------LITYN----------INLCISDSEVAPFSW---LNYIVISRRD- 157
WP_067546935  96 YL-TGVLVVFIRYFKEWIAIYGLIKKGRKI------YQ-EE----------FKLII-HPSSRPSSF---FSYILLPDFL- 152
WP_076930237 103 FA-IGFLFTFIRYLIGLSQIAVIIRNSEKQ------ILSDH----------TVLCVTDKNISPFSW---MKYIVLSRRD- 161
WP_114591738 190 EQLDTRELEGLLAHELAHIARRDVPLNVAIGVIRDLTFFVPPLHLAARWLRQEQEHAADDLASDSTGRPAALASSIL-KV 268
AHB40130     141 RSLTVKELEAVLLHEQSHLISRDPGKVLLGKTFSSMFFFLPIFRELHKDTEAVNELLADQWAIRHQENST-FLRSALkKI 219
WP_013064115 163 --YD-ERNPSILAHERGHIRLHHSWDIVFVEMLTALQWFNPVVWLLRRDLRTVHEYEADASVLSSDSDVSQYIQLLM-RK 238
WP_013065113 156 --YQ-LQDSALLVHERAHINSYHSFDLLLMELAIALQWFNPAIWLTGRELRAVHEYEADASVLSGGVDAHHYLNLLM-DR 231
WP_041620386 186 ---TGTKLEMILKHEQWHIKHRHYVDVFIIEILVRLLWFNPVLWWVRRELRNVSEFHADRSVLDEGQDLYKYQTVIL-EE 261
WP_014774569 156 --TPAGELAAILAHESSHIAHRHSIERILMELMKALLWWNPFAWIAARRLTEAEEFEADNDVLSSGYDRAEYMQTIF-RQ 232
WP_038654844 151 --KESDLLTELLAHERSHIKMRHTLDLVYMSALRAIFWFNPLIWHTGVLLRRVHEYQVDESVLNQGYSAKRYIDLLI--L 226
WP_045089423 158 --YNTDIDGAIIRHEKVHILKNHSADLILVDLFTCLFWFNPFSWLLKREIQSVHEFQADEEVINNGVDIKLYQLLLI-RK 234
WP_067546935 153 --ENDPLFDQVLLHEKMHVKLKHSWDLVFMNIAKGIFWFNPLIYLFENYLREVHEYQADQGVTRKf-SVKGYASLLL-EI 228
WP_076930237 162 --LS-ADNQAVIRHERAHIHLRHSVDMIFFDLFTCIFWFNPFSWLLRREIQSVHEYQADEKVLSQGIDSKQYQLLLI-RK 237
WP_114591738 269 -WEGASrrgvtvvAsmacatmvP--AplpvPAgMParilrqggLRGGAKQIAARVVRLIEGEAR-ATRTRerIELlAL-A 343
AHB40130     220 lAA-------------------PevNl---AA-VS--------NASGPDYFEIRIHRLVDPGTKhKLRPSpvSLV-TT-F 266
WP_013064115 239 -AMGTK-------A--------S--I----LA-NG--------IN--NSTIKKRIFMMLKHKSN-RRAWLk-ALY-IApI 282
WP_013065113 232 -ANAKL-------E--------C--K----LA-NA--------IS--QQTLKNRFQMMARHRSK-PSRLLk-VLY-LLpV 275
WP_041620386 262 -VMEKN----------------P--Y----LA-NG--------FN--NSFTRKRFIMMKNKCHI-RFTTLr-RAL-YVpF 304
WP_014774569 233 -LFGYs----------------P--E----IA-NG--------LR--NSLTKKRFKMMTKQTKS-RHGLLr-LAG-TLpA 275
WP_038654844 227 -SEAGI-------S--------P--E----FA-SA--------LS--YSLTKKRLKMLAKQKR--AGSVRr-LLL-TLpV 269
WP_045089423 235 -SVGEH-------T--------F--A----LA-NN--------FR--KRDLHKRITMMIKTKTN-NRKKWa-YTA-VLpV 278
WP_067546935 229 -LKIGT-------E--------S--Q----MA-SG--------FE--GSQTKKRIMMLAKGHSN-PKFKWr-FLV-GVpV 272
WP_076930237 238 -SVGEY-------K--------F--A----LA-NN--------FR--QRDLHKRITMMKKDKTN-RRVKWs-YAM-GFpV 281
WP_114591738 344 VVLtALtavtVVLPAq-------lADSS---------------LLLGQWSRPVARPVESPALQTFRTLTITETTAFGTSV 401
AHB40130     267 LFI-LV-------------------------------------GWFSLQTPVNAFHSDTMNNNAYHSDTIFLCSHDWACS 308
WP_013064115 283 VAV-SL----VATAKt-------vTEFKpkpanp----vtptaVSNDTINKSNTLVWVLTDEEKKQAKTITPGAPGSINI 346
WP_013065113 276 VAI-TL----ALNAQt-------iIHYQapepap----shpvaDTIQPPASQKVAPDPEVKPYKQQSTQKTEPQPETALL 339
WP_041620386 305 LVL-VF----SLFSFtigkgevryVEKQsek----------seLNNKQELSNELPVAAKSTVNSKNDTLELVNKIINEYP 369
WP_014774569 276 VIG-LL----CAFGFt-------sRAAVivapatapatgtteePADIRTAADAMQKQDKTCTATLSVVDKKDKHPIEGAL 343
WP_038654844 270 VAM-LL----GAFSLt-------tQAQDtkpk-------dkplYIVDGKVFAHDINIIEANTIESMTVLKDKSATDVYGE 330
WP_045089423 279 LLL-SM----IVLSIp-------kLNAQtveeep----akpikVVRTLSMDSVLVEVDTDVVKISETKIDTLTRVRKEIQ 342
WP_067546935 273 ISV-LL----LFFSCe-------hDLDEsfss--------qvqQVIREEGVQLNELPPPQPPFKAQPVSDEVFDIVENQP 332
WP_076930237 282 LFL-AI----IALSVp-------kLNAKvvekennetdlvrekitvsgqvgdeagkpipmvavvnkvtvtktesdlkvil 349
WP_114591738 402 ARPARAATCEDCLTVESTADWRRGVAPAAPVRTAGWAHGGYVWEDGSPVLVTAPRAEPLWGVDARTTRVGVFVVR 476
AHB40130     309 EECRINIEQPVKYIPADMLVPEKKCGND----------------------------------------------- 336
WP_013064115 347 SAAIHDNGVKQNFDGSCYIVRVPKGCWIEDDEDSWIEVSWDRFLFAGKTTKIQLDGVPFDENSAPKLHYSVLKKI 421
WP_013065113 340 TISGTVVDEEGNPLLGTAVKEHDGATGTITDFDGKFSLKVPKGTVVDFLNIGVATVSIQVKSDMTDQKIIMKQE- 413
WP_041620386 370 EKLDIAIKKFMNIQKYDNLMIYFTDMKFILNTLEIQYDTKNEKLKPSMGGSSGVSSERLVGVINQLTESRKAIMD 444
WP_014774569 344 VQAAGPPKGTVTGKDGRAVITVPEGSELKISYIGYEPRTIAVNDENPVVVSLIRNPKAGFTPTDDLPDTPQEQQQ 418
WP_038654844 331 KAKNGVVVITTKKSAGDVTVVSYGKLREANENKDIKIVGRSGAGVQFVGSDVEIPLVIIDGKEFEDIKAIDPNTI 405
WP_045089423 343 TEIQLRGEGVDNLLYIVDGEKVTKEAIKKINPNDILAVNVLKSKASIEQYGEEGKDGVIIITTKSNPNISEIEIN 417
WP_067546935 333 KPPGGTMESWNSYLNENLVYPERARRLGVEGTVILVFVIYEDGSVHDVEVLRGIGGGADEEAVRVVSASPNWEPG 407
WP_076930237 350 ekgegesdgissecpgrsggkdngkssg----------------------------------------------- 377
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