Conserved Protein Domain Family
CDK5_activator

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pfam03261: CDK5_activator 
Cyclin-dependent kinase 5 activator protein
Statistics
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PSSM-Id: 460866
Aligned: 8 rows
Threshold Bit Score: 417.365
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EDW28394             95 HHLHNLANSskdTITNVLD--------AQNENGAIKSEKSSI----DKNLKKHSIFINALSWKKL---STS-HNKKKIDN 158
1_pfamImport          1 SPLPHRPQT---SVCNHLFs-------PGDGGPTFAPQQQES----PRPSAKESVLVQGWNWSKR---NIQpVMSRRSLL 63 
Q9V3H5               96 HNLNNLANAskdTITNVLD--------THNENSVLKAEKSSF----EKNLKKHSIFINALSWKKL---STS-HNKKKIEN 159 fruit fly
WGS:AANI:GJ15405-PA  95 HNFNNLAYSskdTINNDLD--------AHNENSTVISEKSSI----EKSLKKHSLFINALSWKKL---STA-HNKKKVEN 158
EEB17983             55 NNNNNNNHTtsnTNNNNTNhqihanhiNNNDNAKIISEKNTL----EKNFKKHSLFINALSWKRF---STAnNNKKKLDN 127
XP_004570361         20 GPATVGHYTavqNSKNAKD----------------------AaaaaAKSLKRPSI-ISVLPWKRIvavSAKrKGSKKLQS 76 
Q22695                7 SPLPHHHRTqttSVCNHLFs-------PGDGGPTFAPQRDSNtssrSSSNAKESVLMQGWNWSKR---NIQpVMSRRSLP 76  Caenorha...
EGT52205              7 SPLPHHHRTqttSVCNHLFs-------PGDGGPTFAPQRDSNassrNSSSAKESVLMQGWNWSKR---NIQpVMSRRSLP 76 
EDW28394            159 -KNKCANLPTACFKSQFLESTFASS-------------SDKNRNIQLQCNRieehnqpn--------------------- 203
1_pfamImport         64 kSSNMSEATSSKSSNSLVSFTCNAStfttkqsekttvsLDKNQNYKVNAVNdenkeldvl-------------------- 123
Q9V3H5              160 -KNKCANLPTACFKAQLLESSFASS-------------SDKNRNIQLHCNRidehnqqhcnqhphphphqhqlqlqnqhq 225 fruit fly
WGS:AANI:GJ15405-PA 159 -KNKCANLPTTCFKTQLLEASYTSS-------------SDKNKNIQLHCNHieehqhqqh-------------------- 204
EEB17983            128 -KNKNLTI----FRQPLLD-NIHPI-------------VDKNKNIHKSTSI----------------------------- 159
XP_004570361         77 dSGDGGKGSSPDGHAAATTNSASNSl-----------kLKKSQS------------------------------------ 109
Q22695               77 kSGSSSEATSSKSSDSLVSFTRNVStstssqygkisisLDRNQN------------------------------------ 120 Caenorha...
EGT52205             77 kSGSSSVFQKQHHRNPVIVLFLSLEmlgll----lpvnMGKYQYHLTGIII----------------------------- 123
EDW28394            204 ---------hnqpqdirEDSGT-VTAKSQNPSKVKd----------------sIKVNNKNSICNHNKLIQK--QPLTLSL 255
1_pfamImport        124 ---------rfvnldssTSTSFySTWYKRIPRSVDqttiipnyyslreefrrgVEINHGHDAVNNNLNENG--NEYSISS 192
Q9V3H5              226 hqnqnqnqnqnqvqdirEEVMTgPPGKSQNPSKAKd----------------pVKVNNKNSMSNHNKLIQK--QPLTLSL 287 fruit fly
WGS:AANI:GJ15405-PA 205 --------hcnqshiirELPLF-PSTKAQKPSTAKe----------------lGRVNNTNSISNHNKLIQK--QPLALTL 257
EEB17983            160 -----------------PCYYPcLTVSKTVPSLSNpeeldg------hvdinlRSNNNSNNNANTNNTSSSfcEKLGPKT 216
XP_004570361        110 ------------------CANLsSYSSSQDPAATTtttssh-------lpaskTLANVATVVAKKN-------------- 150
Q22695              121 --------------------------YKSVPRPSDtttiipnyyslreefrrgLQINTRQDLVNNNLAS----NDLSVIG 170 Caenorha...
EGT52205            124 --------------------------ISEIPRP-DsttiitnyhtlhnefkrnCQINNRQDLVNNNLTA----NELSIIG 172
EDW28394            256 P-----QQMQPSSMQFKNNNQ-----------------FPRKTVIQASTSELLKCLGIFLHCRCqRLSNFDAGDAVMWLR 313
1_pfamImport        193 SpkhvaKCTIPRLINPDDNGNedlinyegdamlpesanGKRRTIIQASTSELLRGLGIFIANHC-TVKDFNPVHLVTWLR 271
Q9V3H5              288 P-----QQVQASSIQTKNTNQ-----------------IPRKTVIQASTSELLKCLGMFLHCRCqRLNNFDAGDAVMWLR 345 fruit fly
WGS:AANI:GJ15405-PA 258 P-----QQLQISSIQIKNTNQn---------------hLPRKTVIQASTSELLKCLGLFLHYRChRLNKFDPGDAVMWLR 317
EEB17983            217 NlsnipQSQTSSAISNSSHHQv----------------PPRKTVIQASTSELLKCLGIYLHNKCyRLKDFQAGDAVMWLR 280
XP_004570361        151 -------SLTGSGIQPSTAAG-----------------TPKRVIVQASTSELMRSLGEFLCRRCyRLKRLSPTDPVLWLR 206
Q22695              171 SpkhvpR---PRSVLRDDNANcdispia----------eqenvpsEASTSELLRGLGIFISNNC-DVSDFDPAHLVTWLR 236 Caenorha...
EGT52205            173 SpthvpR---PRSI-RDDNANdecdqqe---nyisekrGTKKTIIQASTSELLRGLGIFISKNC-DVSDFDPAHLVTWLR 244
EDW28394            314 AVDRSLLLQGWQDVAFINPANVVFVYMLVRDLVDGEE---SKESDLQASVLTCLYLSYSYMGNEISYPLKPFLVEDSKDK 390
1_pfamImport        272 SVDRSLLLQGWQDIAFINPANLVFIYMLVRDELPGERhliNTLEELHAWTLSCLYVSYSYMGNEISYPLKPFVIGNDRAK 351
Q9V3H5              346 AVDRSLLLQGWQDVAFINPANVVFVYMLVRELVSGEE---SKESDLQASVLTCLYLSYSYMGNEISYPLKPFLVEDSKEK 422 fruit fly
WGS:AANI:GJ15405-PA 318 AVDRSLLLQGWQDVAFINPANVVFVYMLVRELVNGEE---TKESDLQASVLTCLYLSYSYMGNEISYPLKPFLVEDSKEN 394
EEB17983            281 TVDRSLLLQGWQDVAFINPANVVFVYMLIRELVEGNE---ETEHELQILVLTCLYLSYSYMGNEISYPLKPFLVEDSKEQ 357
XP_004570361        207 SVDRSLLLQGWQDQGFITPANVVFLYMLCRDVVSAEV---ASERELQASLLTCLYLSYSYMGNEISYPLKPFLVEAEKEA 283
Q22695              237 SVDRSLLLQGWQDIAFINPANLVFIFLLVRDVLPDERhliHTLEELHAWILSCLYVSYSYMGNEISYPLKPFLIGNDRNT 316 Caenorha...
EGT52205            245 SVDRSLLLQGWQDIAFINPANLVFIFLLVRDVLPDERhliRTLEELHAWILSCLYVSYSYMGNEISYPLKPFLIGNDRNT 324
EDW28394            391 FWDRCLVIVNKLSDKMLKINAEPGFFTEVFTELKSCGQY 429
1_pfamImport        352 FWNRCMSMVTTHSRKMLLLNSSSSYFSEVFSDLKHCLTE 390
Q9V3H5              423 FWDRCLVIVNKLSDKMLKINAEPGFFTEVFTELKSCGQY 461 fruit fly
WGS:AANI:GJ15405-PA 395 FWDRCLFIVNRLSSKMLKINAEPAFFTEVFTELKSCGQF 433
EEB17983            358 FWDRCLNIVNRLSRNMLRINAEPGFFTEIFTELKGCGAT 396
XP_004570361        284 FWDRCLDIINRMSGKMLQINTDPHFFTQVFADLKNESKK 322
Q22695              317 FWNRCVAMVTSHSRQMLLLNSSSTFFSEVFTDLKHCSSS 355 Caenorhabditis elegans
EGT52205            325 FWNRCVSMVTSHSRKMLLLNSSSTFFTEVFTDLKHCSSP 363
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