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iSH2_PIK3R1: Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 1, PIK3R1, also called p85alpha
PI3Ks catalyze the transfer of the gamma-phosphoryl group from ATP to the 3-hydroxyl of the inositol...
View in Cn3D Specific ProteinProteinSuperfamilySuperfamily MembersPubMed
RhoGAP_p85
RhoGAP_p85: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in the...
SH2_nSH2_p85_like: N-terminal Src homology 2 (nSH2) domain found in p85
Phosphoinositide 3-kinases (PI3Ks) are essential for cell growth, migration, and survival. p110, the...
SH2_cSH2_p85_like: C-terminal Src homology 2 (cSH2) domain found in p85
SH3_PI3K_p85alpha: Src Homology 3 domain of the p85alpha regulatory subunit of Class IA Phosphatidylinositol 3-kinases
Class I PI3Ks convert PtdIns(4,5)P2 to the critical second messenger PtdIns(3,4,5)P3. They are heter...
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