Conserved Protein Domain Family
DUF2152

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pfam10222: DUF2152 
Uncharacterized conserved protein (DUF2152)
This is a family of proteins conserved from worms to humans. Its function is unknown.
Statistics
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PSSM-Id: 431148
Aligned: 3 rows
Threshold Bit Score: 821.532
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q2KHV9   6 RLKGL----PGLLSSSWARRLLCLLGLLVLLLWFAGSGARRAAgglqllpWPHGEPGAAEPSACLEAATHAWRSLRERGE 81  cattle
A4IH88   6 RLKVF----PGLLSSSWARRVLAVSGFLVIIYWYIFSGSLFRS-------FWYAGPPRGISGACLHGQTMQWKALAEKGD 74  tropical clawed frog
O45086  13 RIENMdfesKMRMVRRYPKRRLAIIIGVVLFVIFIFS---RGT-------SSGTSFTKQH--QCSAEKLKLWEKEIDEFD 80  Caenorhabditis elegans
Q2KHV9  82 AVLLG-PGV------PSLVANGFLALDVVANRLWVTPGErEPAVAPDFVPFVQLRPLSALPEAGESVLLLREGLLRRVRC 154 cattle
A4IH88  75 VVMVSfPGEetkmqgPTMVGNGHIIVDVGKNNLWVSSLS-VLFHLTNYSPLTFVKSVGALAETHATAIFFKEGLIRTIRC 153 tropical clawed frog
O45086  81 TGINNqs-------vEFV-GNGYIGVDSFG-QLRVQEKNrVLDVETNFYPGLNIEIDGQQPVEVTKMTDFKNGIFKILRC 151 Caenorhabditis elegans
Q2KHV9 155 LQLGTSgpgpaaagpgpasasglltGSGRDCVLLQEDFLAHRGRPHVYLQRIQLNNPTERVAALQTVGPTAGPApRAFTS 234 cattle
A4IH88 154 LQMEAS-------------------DSSHDCVTVREDHFAHRSRPHVYVQKIHIANPSDRVVTFDISSQKPLTG-ETFTT 213 tropical clawed frog
O45086 152 F------------------------SMDGECACVTSQIWAHRTRPNYFVQLIQVSNPTKSTVRLNL---------SRLSS 198 Caenorhabditis elegans
Q2KHV9 235 TLEKVGD-HQFLLYSGRSpPVPTGLVHLVVVAAKKLVDRLQVAPRTQLDETVLWVVHVSGPLNPqvlkSKAAKELKVLQD 313 cattle
A4IH88 214 SVEKVQE-RQFLLSSGRV-SVEDGKIILVVVATKKLVSRLQVSPKSDYDETVFSVVYASEPIDP----GKVSDTFSKLRE 287 tropical clawed frog
O45086 199 NWWAHSKlGELTVHQRQVaRAS------YAVVCTDAPGKVSVSQKREESFRFTCSI-ASKPTSE---------------- 255 Caenorhabditis elegans
Q2KHV9 314 LARKEMLELLE--MPAAELLQDHQRLWAQLFSPGVEMKKITDAHTPSGLTVNLTLYYMLSCSPAPLLSPDLSHRERDQME 391 cattle
A4IH88 288 SAKKEMFELMH--MKTEDLFHEHQQIWSDLFVSGIEMKKIKDLHTPSRDTINITLYYMLSCSLAPLVDPILSNEERDKME 365 tropical clawed frog
O45086 256 EASRDAIRFFQsgKDSKTLDSEHFDGWSKMHLTGFSVANSKAPNTLNGDRINATKYILMSNLRAPTIEHGATLESVKPLE 335 Caenorhabditis elegans
Q2KHV9 392 STLNYEDHCFSGHATMH-AENLWPGRLSSVQQILQLWDLWRLTLQKRGCKGLVRAGAPGILQGMVLSFGGLQFTENHLQF 470 cattle
A4IH88 366 SFLNYADHCFTGHSTMH-AENLWPSSLSGITQLLQLWDLWKLTLQKRGCKSLVSAGAHGLMQGMLLSFGGLQFTENHLQF 444 tropical clawed frog
O45086 336 NLARKSELCYTGHSNLLfPSRLW-QDWDTPTKLFELVNTWMLTFQKRGCNNLLSTGAIGASQAFVQSLTASSYHDSHLEV 414 Caenorhabditis elegans
Q2KHV9 471 QADPDVLHNSYALHGIR-YKN----DHINLAVLADAEGKPYLHVSVESRGQLVKIYACEAGCLDEPVELTSAPQGHTFSV 545 cattle
A4IH88 445 QSDPHVLHNSYSLRGVH-YNK----DLINLAVLLDKDEKPFLHVSVKFQDKLVKLYACEAGCLNEPVELTSEIRGHIFPV 519 tropical clawed frog
O45086 415 ALDAHDLHREMNFHGIPvYSNmgvvGTIRVDIKLDTENRPYFMVSSSS-----QLFVCDGGCLDSPVSLGKT-PVQ-LPV 487 Caenorhabditis elegans
Q2KHV9 546 MVTQPITPLLYISTDLTHLQDLRHTLHLKAIL---AHDEHMAQQDP------GLPFLFWFSVASLITLFHLFLFKLIYNE 616 cattle
A4IH88 520 LVTQPLTPLLYISTDLTHLQDLRHTLHLKEIL---AHEEHMAKQYR------GLPFLFWFSVASLITLFHLFLFKLIYNE 590 tropical clawed frog
O45086 488 KVTKPVTSLLYIAPSRRHLELLRNAIHVSEVGaapAHEEEVIEMHRsgestgGM-TTFWVFVFVVVVAFHLVVAKIVWSE 566 Caenorhabditis elegans
Q2KHV9 617 Y-------CGPGAKPFFRNK 629 cattle
A4IH88 591 Y-------CGPGAKPLFRSK 603 tropical clawed frog
O45086 567 WrkgdmtpYNPYLRNRYSAR 586 Caenorhabditis elegans
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