Conserved Protein Domain Family
2A1704

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TIGR00926: 2A1704 
Peptide:H+ symporter (also transports b-lactam antibiotics, the antitumor agent, bestatin, and various protease inhibitors)
[Transport and binding proteins, Amino acids, peptides and amines]
Statistics
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PSSM-Id: 273343
Aligned: 6 rows
Threshold Bit Score: 819.388
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q21219     66 RTV---LTFYLLNVLKFTDSQSTIFFNGFTVLCYTTPLLGSIVADGYIGKFWTIFSVSILYAIGQVVLALASTKNFQSSV 142 Caenorhabditis ele...
O01840     29 FSFygmKTILFIYLITEHEFSPSKATFIYHLFTCIAYLTPLIGSIMADSVFGRFKVILYGSSIYVVGHVLLSLGAVPFLS 108 Caenorhabditis ele...
P51574     28 FSYygmRALLVLYFRNFLGWDDDLSTAIYHTFVALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVISVSSINDLT 107 Norway rat
Q63424     58 FSYygmKAVLTLYFLYFLHWNEDTSTSVYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLVYVLGHVFKSLGAIPILG 137 Norway rat
P91679     48 FNYygmRTILVLYLTNKLGYNEETATVLFHTFTMLVYIFPLIGALIADGWLGKYKTILYLSLVYSLGAMVVSFGAVPLSG 127 fruit fly
NP_502002  46 FSFygmRAVLTLYFFNILNFSQSFSTVLFHAFTVICYSSPLLGSILADGYIGKFWTIFFISIFYACGQILLAFSSIAPSG 125 Caenorhabditis ele...
Q21219    143 H----------PWMDLSGLLIIAFGTGGIKPCVSAFGGDQFELGQE-RMLSLFFSMFYFSINAGSMISTFISPIFRSQP- 210 Caenorhabditis ele...
O01840    109 Y----------PIRSSLDFSGLFVIAFATGCIKPCVSAFAADQFTE-DQKDLRSQFFSFFYFAINGGSLFAIIITPILRg 177 Caenorhabditis ele...
P51574    108 DhdhdgspnnlPLHVALSMIGLALIALGTGGIKPCVSAFGGDQFEE-GQEKQRNRFFSIFYLAINAGSLLSTIITPILRv 186 Norway rat
Q63424    138 Gk---------MLHTILSLVGLSLIALGTGGIKPCVAAFGGDQFEE-EHAEARTRYFSVFYLAINAGSLISTFITPMLRg 207 Norway rat
P91679    128 -----------MPTKAVTVVGLLLIAIGTGGIKPCVSAFGGDQFSLpAQSFQLAKFFSLFYFAINAGSLISTTFTPILRa 196 fruit fly
NP_502002 126 S----------SHHPLLDLLGLLIVGLGTGGIKPCVSAFGGDQFPA-HYTRMISLFFSMFYFSINAGSLISMWLTPYFR- 193 Caenorhabditis ele...
Q21219    211 CLGQDS-CYPMAFGIPAILMIVATLVFMGGSFWYKKNPPKDN-VFGEVSRLMFRAVGNKMKSGSTPKEHW---LLHYLTT 285 Caenorhabditis ele...
O01840    178 RVQCFG-NAHCFPLAFGVPGVLMLLALILFLMGWSMYKKHPPsKENVGSKVVAVIYTSLRKMVGGASRDKp-vTHWLDHA 255 Caenorhabditis ele...
P51574    187 QQCGIHsQQACYPLAFGVPAALMAVALIVFVLGSGMYKKFQP-QGNIMGKVAKCIRFAIKNRFRHRSKAFpkrNHWLDWA 265 Norway rat
Q63424    208 DVKCFG--QDCYALAFGVPGLLMVLALVVFAMGSKMYRKPPP-EGNIVAQVIKCIWFALCNRFRNRSGDLpkrQHWLDWA 284 Norway rat
P91679    197 DVHCFG-DQDCFSLAFGVPAILMIFSVIIFMAGKRLYRCQPP-AGNMIFGVSRCIADAFKGWQKRRHSEPm--ESFLDYA 272 fruit fly
NP_502002 194 SMSCFG-HDSCYPLAFGIPAILMIVATLVFMAGSFWYKKVPP-KENIIFKVIGTITTALRKKASSSSTHQr--SHWLEYS 269 Caenorhabditis ele...
Q21219    286 HDCALdakclelqaekrnknlcqkkkfIDDVRSLLRVLVMFLPVPMFWALYDQQGSVWLIQAIQMDCRLSDTLLlLPDQM 365 Caenorhabditis ele...
O01840    256 APEHS----------------------QKMIDSTRGLLNVAVIFCPLIFFWALFDQQGSTWVLQARRLDGRVGH-FSILP 312 Caenorhabditis ele...
P51574    266 KEKYD----------------------ERLISQIKIMTKVMFLYIPLPMFWALFDQQGSRWTLQATTMTGKIGT-IEIQP 322 Norway rat
Q63424    285 AEKYP----------------------KHLIADVKALTRVLFLYIPLPMFWALLDQQGSRWTLQANKMNGDLGF-FVLQP 341 Norway rat
P91679    273 KPTVG----------------------SRMVQETKCLGRILRLFLPFPVFWALFDQQGSRWTFQATRMDGNVLG-FQIKP 329 fruit fly
NP_502002 270 LDGHDcalsteck------nlhgncaqRRYIEDIKRLFRVIVMMIPVPMFWALYDQQGSTWVLQAVGMDAKVFG-FEILP 342 Caenorhabditis ele...
Q21219    366 QTLNAVLILLFIPLFQVIIYPVAAKCVRL-TPLRKMVTGGLLASLAFLITGFVQLQVNTTLPTLPEEGEASISFWNQFET 444 Caenorhabditis ele...
O01840    313 EQIHAINPVCVLILVPIFEGWVYPALRKI-TRVTPLRKMAVGGLLTAFSFAIAGVLQLKVNETMEFPPSLGRIYLQRVGN 391 Caenorhabditis ele...
P51574    323 DQMQTVNAILIVIMVPIVDAVVYPLIAKCgFNFTSLKKMTVGMFLASMAFVVAAIVQVEIDKTLPVFPSGNQVQIKVLNI 402 Norway rat
Q63424    342 DQMQVLNPFLVLIFIPLFDLVIYRLISKCrINFSSLRKMAVGMILACLAFAVAALVETKINGMIHPQPASQEIFLQVLNL 421 Norway rat
P91679    330 DQMQVVNPLLILGFLPLFDYIIYPALARCgIRRP-LQKLTLGLLLAALGFFLSAGLEMKMEQAAYRATPIEPDMTHLRIY 408 fruit fly
NP_502002 343 DQMGVLNAFLILFFIPIFQSIVYPTIEKLgFQMTMLRKMAGGGILTAVSFFVCGIVQLFVNPTLPYIPMANEAHLTIINT 422 Caenorhabditis ele...
Q21219    445 DCTITVMSGIHKRVLPHdkYLHEDKKNKSGIYNLFTTKSPAKgngdWTLTYDLSYDGACGDTSKLEKTVKVTAKSKKIIY 524 Caenorhabditis ele...
O01840    392 ESLISDFRYKSDGRLIG--DGMLPKGRTELDAGIYTFNTGLK----NESQEIDISTPNKGYVMAVFRLKDAVEVVKFDYK 465 Caenorhabditis ele...
P51574    403 GNNDMAVYFPGKNVTVAqmSQTDTFMTFDVDQLTSINVSSP---------------------GSPGVTTVAHEFEPGHRH 461 Norway rat
Q63424    422 ADGDVKVTVLGSRNNSLlvESVSSFQNTTHYSKLHLEAKSQDl--------------HFHLKYNSLSVHNDHSVEEKNCY 487 Norway rat
P91679    409 NGMPCRYEISSAVVQTPrvIEPLNVWEDLSLQMTESKEYTFN---------------AQPVSGECPSIIDKLRLQPGKSV 473 fruit fly
NP_502002 423 IPS-CDFNVLIDSREp---FDLLRKS------GIAPDDSVRKpisfTGDDFFQPNITFDNLAPNCPKFTAEPMLAPATSY 492 Caenorhabditis ele...
Q21219    525 VGVGSFGYYQNTANTDKpTDGTGefsm---------givtVFNSSYGGn-------FAMCRQNTSDFDVNHPC-NPRHPA 587 Caenorhabditis ele...
O01840    466 VEKTDNGATRVFVVTAR-EDADT-----------------LVYAINKK--------GKILSSCELKSGSYVDV-IPGIIS 518 Caenorhabditis ele...
P51574    462 TLLVWGP--NLYRVVKDgLNQKPekge---------ngirFVSTLNEM---------ITIKMSGKVYENVTS--HSASNY 519 Norway rat
Q63424    488 QLLIHQDGESISSMLVKdTGIKPangm---------aairFINTLHKD---------LNISLDTDAPLSVGKD-YGVSAY 548 Norway rat
P91679    474 SYFLAQD--KLVEFADGlQMAATdtgrt--------svraLLNTPDGE---------GPVLLSTESATSQEPP-LTLDKG 533 fruit fly
NP_502002 493 VLTLSPNGWAY--NAVRpEKPKSgkgelsmglnlivpcdkIPSNVTWEqcngtegySGAIALCKVESDVITDNnNVCDPT 570 Caenorhabditis ele...
Q21219    588 DFYFWETDYNSHTDDRDQNATITGSLssqpavtykqksvkpgywqlyyllntpkdvdrqtynktatlvaptNygfhrvkq 667 Caenorhabditis ele...
O01840    519 DPNVRLYWGPKNSCSGVDCPNTVTLN---------------------------------------------A-------- 545 Caenorhabditis ele...
P51574    520 QFFPSGQKDYTINTTEIAPNCSSDFKss---------------------------------------------------n 548 Norway rat
Q63424    549 RTVLRG-KYPAVHCETEDKVFSLDLGq----------------------------------------------------- 574 Norway rat
P91679    534 NVPQLHRITPGFARVDINGKKVASFEa----------------------------------------------------- 560 fruit fly
NP_502002 571 AKGKFYVLSNANPLDVHDFSKKSTVTafgrtyspiemkpgtyr-----------lfytddsrthftplnlpPvq-----q 634 Caenorhabditis ele...
Q21219    668 gGVFIYALTGTYENPKI-HElq--ivQSNSVSILWQIPQIVVITAAEILFSITGYEFAYSQSAPSMKALVQALWLLTTAA 744 Caenorhabditis ele...
O01840    546 -QMGAVHVLHIHPSTTEgDFn-----LLVRPNSVSILWSLPQYIIITLGEVLLSVTGLEFAYSQAAPNMKSVLTAMWLLT 619 Caenorhabditis ele...
P51574    549 lDFGSAYTYVIRSRASD-GClevkefEDIPPNTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLT 627 Norway rat
Q63424    575 lDFGTTYLFVIT-NITS-QGlqawkaEDIPVNKLSIAWQLPQYVLVTAAEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLT 652 Norway rat
P91679    561 -KEGRLYSILVT-GSAR-DGyqhnviEVVALSTVSILWQLPQIVVMTAAEVMFSVTGLEFSYSQSPPSMKSVLQACWLLS 637 fruit fly
NP_502002 635 dHMGGQYLITVSTRSKNdSEvlatteSLVSYNRVSILWQIPQYVILTAGEVLFSITGLEFAYTEASPQLKSVVQALWLFT 714 Caenorhabditis ele...
Q21219    745 GDSIIVVITILNLFENMAVEFFVYAAAMFVVIAIFALLSIFYYTY 789 Caenorhabditis elegans
O01840    620 VFAGNLIDMMISGTRLIPHPALEFFFYSTLMVIVMGVFILLAMQY 664 Caenorhabditis elegans
P51574    628 VAIGNIIVLIVAEAGHFDKQWAEYVLFASLLLVVCIIFAIMARFY 672 Norway rat
Q63424    653 VAVGNIIVLVVAQFSGL-AQWAEFVLFSCLLLVVCLIFSVMAYYY 696 Norway rat
P91679    638 VAIGNMLVVVIAEFKFTSSQSGEFTLFASLMLVDMMIFLWLARSY 682 fruit fly
NP_502002 715 TAIGDLIVVVIFMLNIFSDVAVQMFVFGGIMLFVIFVFILLAVFY 759 Caenorhabditis elegans
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