Conserved Protein Domain Family
nifB

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TIGR01290: nifB 
nitrogenase cofactor biosynthesis protein NifB
This model describes NifB, a protein required for the biosynthesis of the iron-molybdenum (or iron-vanadium) cofactor used by the nitrogen-fixing enzyme nitrogenase. NifB belongs to the radical SAM family, and the FeMo cluster biosynthesis process requires S-adenosylmethionine. Archaeal homologs lack the most C-terminal region and score between the trusted and noise cutoffs of this model. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other, Central intermediary metabolism, Nitrogen fixation]
Statistics
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PSSM-Id: 273539
Aligned: 4 rows
Threshold Bit Score: 781.721
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P24427    41 MAPAIIEQIKDHPCFSREAHLYFARMHLAVASACNIQCNYCNRKYDCANESRPGVASHRLTPDQALRRAIAVANEVPQLS 120 Rhizobium leguminos...
CAC27790   9 STSAAEDDISRHPCYSEEAHRFFARMHIPVAPACNIQCNYCNRKFDCVNESRPGVVSEVLTPEQAERKVKGVAAQLMQLS 88  Paenibacillus durus
CAA68008  18 VNEQLARKAAQHPCYSVSGHHRFARMHLAVAPACNLQCNYCNRKYDCSNESRPGVVSELLLPGQAVAKARQVAAAIPQLS 97  Pantoea agglomerans
P46044    42 QDPEIAEKIANHPCYTAEAHQYYARMHVAVAPGCNIQCNFCNRKFDCANESRPGVTSTLLTPEDALAKVNVVASEIKQMS 121 Frankia alni
P24427   121 VVGIAGPGDACYDWRKTKATLIPIAREIPDVKLCISTNGLALPEHVDDLVDMNVGHVTITINMVDPRIGTKIYPWIFYDG 200 Rhizobium leguminos...
CAC27790  89 VVGIAGPGDPLANADKTFDTFARVKKHVPDVITCLSTNGLTLYRHIDRIVELGIGHVTITINAIDPDVGKEIYPWVSDEG 168 Paenibacillus durus
CAA68008  98 VVGIAGPGDPLANIGRTFQTLELLRQQLPDLKLCLSTNGLMLPDVVDRLVDIGVDHVTVTMNALDPAVAEKIYAWLWYEG 177 Pantoea agglomerans
P46044   122 VLGIAGPGDPLANPKPTFRTIELVARDCPDIKLCLSTNGLRLPEFVDRIADLNVDHVTITINMIDPEVGERIYPWVAWRG 201 Frankia alni
P24427   201 RRYNGIDASRILHERQMLGLEMLTERGILAKVNSVMIPGVNDEHLIEVNKWVKDRGAFMHNVMPLISERshGTFYGLNDQ 280 Rhizobium leguminos...
CAC27790 169 VRYEGREAAALLISRQLQGVEELAKRGILVKVNSILIPGINDKHLVEVSKKVKELGATLHNVTPLIIAP--GSQYEKDGR 246 Paenibacillus durus
CAA68008 178 ERYTGRMAADLLIERQAEGIRKLIEKGVLVKINSVLIPGINDQHMQAVSQQAGEWGAFLHNIMPLISRPehGTVFGLNGQ 257 Pantoea agglomerans
P46044   202 KRYTGREASKILSEQQLAGLAALTERKILCKVNSVMIPGINDEHLVEVSRTVKGLGAFLHNVMPLVSAPehGTVFGLTGQ 281 Frankia alni
P24427   281 RCPATSELIALRDRLEGG----TQVMRHCHQCRADAVGLLGDDRAREFTLGQFP-ADETYDSAKRNAYRQLIERERr--- 352 Rhizobium leguminos...
CAC27790 247 KAPRPRELNQLQEQLSEGg---TKLMRHCRQCRADAVGLLGQDRNQDFQLETME-ADPVIDLDAREQFQQELDSKIr--- 319 Paenibacillus durus
CAA68008 258 AEPDADMVASVRKSCGMS----MPQMTHCHQCRADAIGMLGEDRNAAFPLASVP--------VNPPPYLPVLHQR----- 320 Pantoea agglomerans
P46044   282 RGPTPQELKALQDRCEQDdgaeMNMMRHCRQCRADAVGLLGEDRGDDFLPETFQgREIVYDLAGRQQAHEEIERWRteva 361 Frankia alni
P24427   353 --gQTLEESDAATPVSAPSDEl------LLIAVTTKGGGRVNGHFGHAQEIQIFSVCQKGNGLIGHLKIDPYCLG--GWG 422 Rhizobium leguminos...
CAC27790 320 ---QRLIAKENRRSILDENKK-------TRVAVASRGGDKVNQHFGHATEFMIFDTDGAEVKFIGIRKIQAYCHGtaDCN 389 Paenibacillus durus
CAA68008 321 ---AQLHASIVSQGGSEEADA-------CLVAVATSQGQAVDQHFGHADRFTLYSLSAAGVMQVGQRFTPRYCRSpdDCE 390 Pantoea agglomerans
P46044   362 atrQTLNIATGARTPDVPAAEpvrpaevVLVAVATKGSGVVNQHFGHAGEFWIYEAGPGWARLVQTRDVDRYCNGpsDCD 441 Frankia alni
P24427   423 -EEAT--LNTIIDALKGLDVLICSEIGKSPKNKLARRGVRATGAYDgsyIEQAIGALYRAV 480 Rhizobium leguminosarum bv. trifolii
CAC27790 390 -GDKGetLQEITSILSDCRILLSSGIGDAPRAALNKAGVLPLVRKGg--IQEAILESVKYG 447 Paenibacillus durus
CAA68008 391 pEDAAqnMDALLELLADVKAVFCARIGLTPWKRLEAAGIEPQVDGAwqpVETAAWRNGGsn 451 Pantoea agglomerans
P46044   442 -EDASk-LDRTIEMLSDCAAVLCSKIGLGPREALEEAGIEPVEIYDl--IDKAVAEIGARL 498 Frankia alni
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