6TED


Conserved Protein Domain Family
CDC73_N

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pfam16050: CDC73_N 
Paf1 complex subunit CDC73 N-terminal
CDC73_N is the N-terminal region of the members of CDC73_C, pfam05179. CDC73 forms part of the Paf1 post-initiation complex. The exact function within the complex is not known.
Statistics
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PSSM-Id: 464994
Aligned: 17 rows
Threshold Bit Score: 235.001
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6TED_X         1 MADVLSVLRQYNIQKK--EIVVKGDEVIFGEFSWPKNVKTNYVVWGTGKEGQPREYYTLDSILFLLNNVHLSHPVYVRRA 78 
XP_002109863   1 MADCLSFLRLYNIEKK--DVIETDERIIFGDYSWSKFTNTNYLKYGTGRDGATKEYYTLASLVFLLKNVDISHSVYAQKA 78 
2_pfamImport   1 MADALSILRDYNISKK--PIDEQEGHVIFGDFSWPKDVKTNYIIWGTGKDGTSKEYYTLESILFLIKNVKLSHPLYVRHA 78 
XP_009026571   1 MADALSILKQYTIDKKinDIIEKDDQIIFGDFAWPKTAKTNYLIYGTGKDGIAKDYYTLDCIVFLLKNVHIPHASYVKQA 80 
EKC22062       1 MADVLSNLRQYNINKK--EIKEEDDQVIFGELAWPKTVKTNYVIYGTGKDGIPKEYYTLDCILFLLKNVQLQHALYVREA 78 
XP_012547997   1 MADPLSLLRQYNVNKR--EIIERDNQIIFGEFSWPKNVKTNYLIWRSGKEGSVKEYYTLECLLFILKNIHLTHPVYVRQA 78 
Q5TNB0         1 MADPLSLLRQYNINKK--EIIERDGQIIFGEFSWPKNVKTNYLKYGSGKKGAPKEYYTLECLLYILKNVGLQHSVYVRQA 78  Anopheles gambi...
XP_002069732   1 MADPLSLLRQYNINKK--EILERESQIIFGEFSWPKSVKTNYLKYGSGKKGAPREYYTLECLLYLLKNVMLQHSVYVRQC 78 
3_pfamImport   1 MADPLSFLRQYNISKK--EIIERDNQIIFGEFSWNKNVKTNYLKYGSGKKGAPREYYTLECLLYLLKNITLQHSVYVRQC 78 
EFX74457       1 MADPLSLLRQFNVNKK--EIIEREGQIIFGEFSWPKTVKTNYLIYGSGKDGAPRDYYTLECLLFLLKNVQLQHPVYVRQA 78 
6TED_X        79 ATENIPVVRRPDRKDLLGYLNGEASTSASIDRSAPLEIgl--qrST----QVKR--AADEVl---AE--AKKPRIEDeEC 145
XP_002109863  79 IAAGIPLVSRPDRKDLLAYLNGETSVSASIDKSAPLELgqqhvvPAaplpQVKR--SVDEGt---NSdtLKRVKTDE-D- 151
2_pfamImport  79 AAEEIPVVRRPDRKDLLAYLNGEIATSNNVDKSAPLDItl--qrPS----KVKRvtTTNDDvtntMEplSKRSRLED-AQ 151
XP_009026571  81 AAASVSVVRRPDRKDMLSYLYGEVSSLSSIDKSAPLEIsl--qrPV----QLKR--GAEETl---GDhdSKKPRIEE-AS 148
EKC22062      79 AAKGVPVVRRPDRKDLLSYLNGETTSSTNIDKSAPLEIpl--qkPP----QAKR--GATDT----HEgdKKKPRLEE-KQ 145
XP_012547997  79 AAANIPPVRRPDRKELLAYLNGETATCASIDKSAPLEI------PT----QVKR--TLDNDg---GEsaAKKPRIEE-TH 142
Q5TNB0        79 AAEDIPAVNRPDRKELLQYLNGETNTCASIDKSAPLEI------PT----QIKR--PAESDg---LDslAKKARYED-TQ 142 Anopheles gambi...
XP_002069732  79 AAEDIPAVNRPDRKELLAYLNGESQTCASIDKSAPLEI------PT----QVKR--SADGDpi-sGEvaAKKPRFEE-TQ 144
3_pfamImport  79 AAEEIPAVNRPDRKELLAYLNGETNICSSIDKSAPLEI------PT----QVKR--SIENDgs-aIEslSKKARYEE-VQ 144
EFX74457      79 AADSIPVVRRPDRKDLLAYLNGETAASASIDKAAPIEI------PI----QVRR--IAGTAqaggSVpaSKKPRLED-QQ 145
6TED_X       146 VRLDKERLAARLEG-HKEGIVQTEQI----RSLSEAMSVEKIAAIKAKIMAKKRSTIKTDLDDDIT------------AL 208
XP_002109863 152 VKVDKNRLESRLEAnVKDKVVTTNQL----RPLSERISAEKIAALKAKRIAHKRETIKDDTITE---------------I 212
2_pfamImport 152 LAMRNKRLAERLD--RGDKSVTTETI----KSLSDSISAEKIAAMKAKFVARKRKTIQEVDDPTEGf----------gIM 215
XP_009026571 149 MEKHRVRLAMKLSSpSREESVIPSQVinsdSTICQTMSIEKISAIRAKIIARKRKTIKDDMLD----------------A 212
EKC22062     146 VQEARLNWINKIDA-PRETAVLQAALa--sSSLPEAMPLEKIAAIKAKRLAKKRTMIKVDENDIQTg-----------AL 211
XP_012547997 143 VQKVREQLAARLDA-PKEASVTVDNI----KSLSEAMSVEKIAAIKAKRLAKKRTTIKSNDYSDTLgv---------vGS 208
Q5TNB0       143 VQKVKEQLAARLDVnKKEASVNIDNI----KSLSETMSVEKIAAIKAKRLANKKVTIKRTDNDDAMg----------vGP 208 Anopheles gambi...
XP_002069732 145 VQKVREQLAARWDVnQKETAVNMDNI----KSLSETMSVEKIAAIKAKRLANKRTTIKRTDNDEAAm-----------GT 209
3_pfamImport 145 VQSFREQLAARLDVnKKEVSVNIDNI----KSLSETMSVEKIAAIKAKRLANKRTTIKRNDNDEAM------------GT 208
EFX74457     146 MQRVKEVLAARLEApRQDSLINVNKI----QSLSEAMSIETIASLKAKRIANKRKTIKGDTEDMGLglgtslglagssSS 221
6TED_X       209 KQRSFVDAEVDVTRDIVSRERVWRTRTTILQSTGKNFSKNIFAILQSVKAREEGRAPEQ------RPAPNAAPVDPTLRT 282
XP_002109863 213 EQRSFADAEVDVSKDIISKEKVVRTRETVMRSAKKSFT-NILDVITNIQLREQGRNLNh------NHKTPPPTEPPPKKS 285
2_pfamImport 216 TSLLYV---FDITSEVLSRERNWRTRSTVLQSAGKNFSKNVFAILSSIKAKEEGKSQEKdss-svTALLPTKSNPAGVKK 291
XP_009026571 213 ESHAYVEVGVDVTRDIISKERQWRTRTSILQSSGKDFSKNIFGILQSIKVREEGAIKQQvepssnSSNNIVSSQPSSTNP 292
EKC22062     212 EQRSFVDAEVDVTRDIVSRERLWRTRTTILQSQGKQFARNIFGILQSIKAREEGTQKH----------HPAPHTPSVAPA 281
XP_012547997 209 DLRAILDYDVDLTKDIISRERQWRTRTTVLQSNGKMFAKSILAHLASIKAREEGR--------------PGIPRAQPVIL 274
Q5TNB0       209 DLRVILDFDVDSTKDIVSRERQWRTRTTILQSNGKIFAKNIFAILQSIKNREEGRGRP-------AQQPVKLPEPPRVIR 281 Anopheles gambi...
XP_002069732 210 DLRAILDYDVDSTKDIISRERQWRTRTSILQSTGKIFAKNLFAMLQGIKAREEGRQGRPq----vSNNAIKMPEPPQRIN 285
3_pfamImport 209 ELRAILDYDVDSTKDIISRERQWRTRTTVLQSNGKIFAKNIFAILQCIKAREGGGNIRm------TSQTAKVPEPIKINK 282
EFX74457     222 ELRGMLDYDFDVTKDILNRERQWRNRTSVLQSSGKVFSKNIFAILQGLKAREDGKLRGHss---iPPGAGRAVVPPGGAP 298
6TED_X       283 kqPI--------PAAYNRYDQER 297
XP_002109863 286 vaPI----------PYSRYDQER 298
2_pfamImport 292 saPQ---------AGYSRYDQER 305
XP_009026571 293 skPAi------qPTSYSRYDQEl 309
EKC22062     282 kpPQp-------VAGYNRYNQEs 297
XP_012547997 275 qqPTvlp---aqQTQYNRYDQER 294
Q5TNB0       282 pqPq--------PTQYNRYDQER 296 Anopheles gambiae str. PEST
XP_002069732 286 kpPQq------qLSQYNRYDQER 302
3_pfamImport 283 pqPq--------VAQYNRYDQER 297
EFX74457     299 --PGmgppvqqqGPVYSRYDQER 319
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