Conserved Protein Domain Family
Na_H_Exchanger

?
cl01133: Na_H_Exchanger Superfamily 
Sodium/hydrogen exchanger family
Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus, this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family.
Statistics
?
Accession: cl01133
PSSM Id: 470090
Name: Na_H_Exchanger
Created: 8-Feb-2008
Updated: 4-Oct-2023
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap