Conserved Protein Domain Family
MBR1

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pfam17058: MBR1 
Mitochondrial biogenesis regulation protein 1
In yeast this protein participates in mitochondrial biogenesis and stress response. And also seems that may affect the NAM7 function, possibly at the level of mRNA turnover.
Statistics
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PSSM-Id: 435712
Aligned: 7 rows
Threshold Bit Score: 142.886
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CCF57975      81 LCLSMFERGVQDPCSAEC--DNEDENTlmklsqmenvsdnnnnignNMNEDISYFDlenricsdeeqefkifgspdsgsr 158
CCD27409      42 LCLNLFERAVQDPYCSGC--DIEDDEA-------------------SLASMLDTSD------------------------ 76 
CCK69669       2 LSHAIFERDVQDPCSAAC--DCADACKntas----------------aapvVGVSD------------------------ 39 
XP_003671630   1 MSLDIFERGVQDPFSEAC--DNEDVKDllsvsted----inpnvvtANTSPISSSDf----------------------- 51 
XP_003644973  72 NGMKIFERSVEDQCSDVWysDTSDEDK---------------------------SDi----------------------- 101
XP_003673475  35 CCLNMFERAVQDPCCQAC--DMEDENNsedl-----------fqnyTAIRELERSD------------------------ 77 
EJT43705      29 DCLNFFERAVQDPCCEAC--DTEDADD-------------------ELRAKLNNFNfqsdssp----------------c 71 
CCF57975     159 rrsnyETIDPLKSSSRSFSNVPIQEfarsNSRSPNTRKLE------------------------SLSSNEPFNEKIHRHe 214
CCD27409      77 -----EELPDQNYILLSPSEQKWYQygqiTDENSDIGEVDpldrqtpilepikdydtlddvfsySFKSNTPTHPNTNRRv 151
CCK69669      40 --------SPVFASRCNLPEKV---------------------------------------------------------- 53 
XP_003671630  52 ----hGEYRPVEEIQYPQKSSSFYM----DNNNNNINNKNrntr------------------------------------ 87 
XP_003644973 102 ----eEELDPLKEV---------------EKHKHRKGRHNgav------------------nscLDSKAGGGGLQGQGS- 143
XP_003673475  78 -----KSLSPLNETFYQTDEVDP------LEENGRGAGKStdl------------------psnIMQLNDPLRQQPSRHh 128
EJT43705      72 sgtcqQTLNPLCEI----DEVQPERpalaPSRNGSVSGVNsda------------------nsiPSYTHDPNDTKYGAM- 128
CCF57975     215 rhfstsstvsppt----------wtnpftskqivrpqQNFRKVQTMPYI---------------SNAIRANKASTGTNVH 269
CCD27409     152 tmtstcdfqkn--------------ndgyidsspespRNLRKVKTVPFP---------------PNSQNYEKNITNFQIL 202
CCK69669      54 -------------------------------------TALRKIHTAPHPwengpsqfllvctggPTPISPPSPLSEQRPV 96 
XP_003671630  88 ---------------------------------ngigSSLRKIRTAPHK---------------LGSLSPLMTQEPFHNL 119
XP_003644973 144 -------------------------------------GNMRKIGTSRTA-----------------SCGTTSTNKKSQIC 169
XP_003673475 129 rraatlstskytihnengndndnndtnplflkqrmkpQDLRKIKTAPYFd--------------TGCMSELPNKPNYQIN 194
EJT43705     129 -------------------------------------PSLRKAKTTSYF---------------------TSPSSNNSTM 150
CCF57975     270 ENreersns------sisyppELIRNSRANSANFLYQLSRQP---------------LRPSIRSASINKVSESTFPGCKA 328
CCD27409     203 RSs-----------------pFLLRNSRRNSSDLIRSLSDNPsrqqssiqstrssilNIPSTFSSNLNTTTINNSNNINS 265
CCK69669      97 RK-------------------------RANSFAFIHRLSRNSsmskmfdyadntasrPKFSRSGSMDDGLAPSLAQLQVS 151
XP_003671630 120 QKatweeeqerqneestsplcFPLRRNRANSSSFIHHLSRQS------------------TNTNSNNNSGIFESPQFLNK 181
XP_003644973 170 SRchrlkpvrs--hsrsafdlEELAINRPRTNSIMLQLSRQT---------------TRQSFLDGNNTTTGSIVTHSAND 232
XP_003673475 195 SSp------------------FFLRNSRRNSCNLIHQMSRKP--------------------------TQSEPRPYSSMS 230
EJT43705     151 RNslkkcn----------tnvngLLTNRRNSSS-----SRQS-------------------IPELYSGACTRKKSNVLLK 196
CCF57975     329 GDTHHDNDTFT----------GTRRTTSR------SSCSS--ILTHLYGIEKYVSSDLDA 370
CCD27409     266 NDINNNSRYGRtstknsgfdiAASPIQRRyrprfsPDCYSsrIPSHLYCLENHISSNLDA 325
CCK69669     152 ---------------------PTAPLTRH------NSCYA--IPTHVYGLEKYVTSELDE 182
XP_003671630 182 QTNNNTINFSNtttptrcnsvTSKPLSRH------SSCFA--IPTHIYGLEKYVLSELDA 233
XP_003644973 233 GNPLDE---------------TMCRTRSR------SSFTA--IPTHVYSLEKYISTELDS 269
XP_003673475 231 ANARQENNKIDtfsdyiadspNGQRSLSQ------VSCAA--IPTHLYGLEKYVTSELDA 282
EJT43705     197 NETPQSEFSSSslqhsntrsfSLPRSRSR------SSAIA--IPTHLYGLEKYVSPELDT 248
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