Conserved Protein Domain Family
cobD

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PRK01209: cobD 
cobalamin biosynthesis protein
Statistics
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PSSM-Id: 234919
Aligned: 251 rows
Threshold Bit Score: 238.549
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
111222304   4 RAGGLMLGAALDALLADPARR----HPVAGFGRAAGRLERLLYRDDr----AAGALYTTLLLAAVVVPAAAAERAgartr 75 
284161422   1 -MIELVLAIAFDLLFGEPPNRv---HPVVWFGKITAKIDRAYKRRNpltdfLAGIVCTTVVLFFALVLSFIPRFLpf--- 73 
14590284    1 -MYELILALGWDLLLGEPPAVv---HPVVWFGKLIAFIDSHYSRRSpaidfLAGLFATLVVLSFAFLLSILPLYApy--- 73 
18976668    1 MDMTLPIALLIDLMFGEPPAIi---HPVVGFGKVIEFFDNKYRRRSpyldfLVGAISSLVVIGLAFILSHLPNFLpn--- 74 
14520264    3 PLILLGLALIWDLLLGEPPAKi---HPVVWFGKIAGFLDNRWRRRGki-gfLAGAFVTFIIVALAFFLSLIPSYLtf--- 75 
240102601   3 ALIVFLLALLWDLLLGEPPVEl---HPVVWFGRVAGFLDGKWKRRGplpdfLAGALTALLVIAFALALSLLPLYL----- 74 
57640798    3 ALVPFLLALAWDLTLGEPPAKl---HPVVWFGRIAGFIDSRYKRRSpvldfTAGLLTALVVITFAFLLSIVPFYApf--- 76 
212223828   3 ALVTFVVALLWDFLLGEPPALv---HPTVWFGRLIGLFDGIYRRRSsildfLAGTSASLFVITFAFALSKLPELLpe--- 76 
126460146   5 IWLALALALALDVVYPEHRGLllkiHPVHTSYFMALRLAKRRRDr------LWGIAVWLAVEAAHLTPFAALLAL----- 73 
118431698  16 LAAGLAVGLMLDLAYPEHRGLalklHPVHTSYIMALRLVRPGAGr------AWGAAIWLLTISSHMMVYASLL------- 82 
111222304  76 gsapiapAAPvaPaapvspvapialadsvapwAPVVMTAALTWVVLGGASLRRQGRRLGAELRAGDLAAARARLPTLCGR 155
284161422  74 -------------------------------pFNLIAEVYLLKSSFAIKSLYQHVKATICE----DVEEMRRAVSLIVSR 118
14590284   74 -------------------------------pLNYLLSVYLLKSSFAIRSLYEHVRRTMKD----DVEEMRKEVSMIVSR 118
18976668   75 -------------------------------pFNLILSIYLLKSSFAIRSLHDHVKRTITP----DLEEKRRAVSMIVSR 119
14520264   76 -------------------------------pLDYLLAIYLLKSSFAIRSLYEHVARTVTE----DIEEKRKTVSMIVSR 120
240102601  75 -------PFP----------------------LNYALAVYLLKSSFAMRSLHEHIARTITE----DINEKRKAVSMIVSR 121
57640798   77 -------------------------------pLNYFLAAYLLKSSFAIKSLHEHVSRTITD----DIEEKRRAVSMIVSR 121
212223828  77 -------------------------------wLGFALGVYLLKSSFAIKSLAQHVENTVRD----NIEEQRKYVGWIVSR 121
126460146  74 -------AAFhp-------------------lAWALAAAATLKFSISYKLLVDICRRVQKALERGDLAEARRWVSHIVRR 127
118431698  83 -------AASylVhp----------------aLHTLAVGVIVKLSMPLRLLLDTCIKASRMAAAGRVECSRRLVQGIVRR 139
111222304 156 DPSRLDEAGVARGAIESIAENTCDAVVAPLWWGAFAGLPGLAGYRAVNTLDAMIGHHSDRYERFGWAAARLDDLVNLLPA 235
284161422 119 DVSKLDRHHLISASIESLAENIVDSVISPIFYYMLFGLSGALIYRAINTLDAMIGYRNEKYEYFGKFSARLDDILNFIPA 198
14590284  119 DTSKLGREHLISASIESLAENTNDSVVAPLFYYLLFGLPGALVYRAVNTLDAMVGYRTSRYEYFGKFSARLDDILNFLPA 198
18976668  120 DTKSLDEPHLNSAAIESLSENINDSVIAPLFYYLIFGLPGAVVYRAVNTLDAMIGYRNEKYEYFGKFAARLDDLLNFVPA 199
14520264  121 DVKVLDLAHLNSAAIESLAENLNDSVVAPLFYFMLFGLPGAMVYRAVNTLDAMFGYRDERYEYFGKFPARLDDILNFIPA 200
240102601 122 DVKNLDESHLNSASIESLAENLNDSVIAPLFYFLLFGLPGALFYRAVNTIDAMLGYRNERYEFFGKFSARLDDVLNFIPA 201
57640798  122 NTKVLDEAHLNSAAIESLAENLNDSVVAPLFYFLLFGLQGAVIYRAVNTLDAMLGYRNERYEFFGKFSARLDDALNFIPA 201
212223828 122 DVSKLDRAHLNSAAIESLAENITDSIVAPLFYYLLFGLSGALVYRAVNTLDAMIGYRDERHEYFGKFAARLDDLLNFIPA 201
126460146 128 DVSSLEEAGVASAALESLAESLVDGFTSPVFYAVLLGPLGALGQRVANTLDGALGYKTPEFKDVGWVSARADTVLNFIPA 207
118431698 140 DLSGEPLGRVLSACIESTAESLVDGYTSPLTYYILLGPLGALLQRLSNTLDGAVGFKTPLLYRQGWFSAKADTLLNFIPA 219
111222304 236 RLCALATCACAPVVGGSVADAFWVMRRDGRSHPSPNAGMAEAAFAGALGLRLGGELRYPYRVEHRPELGFGRPP--RGAD 313
284161422 199 RITVLLFL---------PLKPKRVWQYCRLAKFKINSDKPIACMSAVLSVWIEKEGVYRF---------EGRNP--RLED 258
14590284  199 RITVLLFL---------PLNPRRVIRYYKMARFKVNSDKPIAAMSAVLGIWLEKPNIYRF---------PGRDP--RMED 258
18976668  200 RITVLLFL---------SLGGRKVIRYYRMAKYKINSDKPIAAMSAVLGVWLEKPNYYKF---------PGRRP--ENED 259
14520264  201 RLTVLLY----------LPFGVKVLKYYKLARFKINSDKPIAAMSAVLGVWLEKPGAYRF---------PGREP--RDED 259
240102601 202 RLTVLLYI---------PLGGLKVLRHYHLAKFKINSDKPMSAMSAVLGVWLEKPGVYRF---------PGREP--KNKD 261
57640798  202 RLTVLLYL---------PLGGRKVPEYYRLARFKINSDKPMAAMSAVLGVWLEKPGVYRF---------PGKEP--KNED 261
212223828 202 RITVLLFLPLS------PRKVLEYWGKAKFKI---NADKPIAAMSAVLGVWLKKEGVYHF---------EGREP--TLED 261
126460146 208 RLTALLIALLAPIAGGDVRKALAVWLRWHNATESLNAGHPMSAMAGALGVRLEKRGHYVLNPSGRPPTA---------AD 278
118431698 220 RLTAVMVALAAPLAGASTLGSLRCIARCARLLESVNAGYPISAFAGALDVRLEKKGFYIV---------NGGAPypGWRD 290
111222304 314 VLAAARLSGA--VSALCL--------AVTAL-----AGG 337
284161422 259 VKKALKVYCLivAIFLSL--------VFMLEfilvnHA- 288
14590284  259 IERALKVYVIvvSEWILL--------LLLGVil------ 283
18976668  260 IKRALKVYWIivVEFLLI--------VAIILygg----- 285
14520264  260 IKRALDVYKLvvAEYLSIvfvlkvvqLCLNP-------- 290
240102601 262 IKRALKVYWFvvAEWVGI--------VLLLLakgvcPCW 292
57640798  262 IKRALRIYWLvvTGWVIV--------VVLLLatgvcPCL 292
212223828 262 IRRALRIYWIvvGEWIAV--------VLLLLltgvcPCL 292
126460146 279 IARGVKLATAvtAVYFVV--------MFLIWtivqyLKV 309
118431698 291 GLKASRLAVSaaSLYTVL--------AALAIalgggAG- 320
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