3HDO,4R8D


Conserved Protein Domain Family
HisC

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COG0079: HisC 
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Statistics
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PSSM-Id: 439849
Aligned: 742 rows
Threshold Bit Score: 189.187
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3HDO_A        14 KGyi-pGYQPPd--------IASWIKLNTNENPYPPS-PEvvkaILEelgpdgAALRIYPSA-SSQKLREVAGELYGFD- 81 
WP_083510645  13 TPwpahGGQLStlarhfpqaPTPLIDLSTGINPFAYPfTP----PGA------DALSRLPDPaEEEALRFAASQAYGVS- 81 
WP_083537065  36 dvfrehGGRIDaasalfplaPRPWIDLSTGISPWAYPhAD----LAH------SVFARLPEAdHIAELEHAAATAFGVEd 105
WP_014496551   1 --mrehGGNLDlaqqrfggrAEDWIDLSTGINRLPYPvGE----VSA------RAWNALPSRaEIESLHQAAQHAYRT-- 66 
WP_013045446   1 --mrehGGNIDvaaarygfaPDDMLDLSTGISPFIYPlSP----ITV------DALQALPTAaSLTACVQAARHAYKVPd 68 
WP_014457394  36 hyipahGGQVQkimqmfadaPQPYVDLSTGISPFAYPaKL----PDL------SALHILPEEaEETALQHAAAMAYGISd 105
WP_054540028   1 --mrdhGGNIDgaiarfggkPEEWIDLSTGINRAPYPlPE----ISA------AAWRSLPTRaAQEALIRAAAQAYGT-- 66 
WP_048533724   5 ppprdhGGNLEaalarfggaGPAWLDLSTGINPAPFPvPA----ISP------EAWAALPRKrAMDGLIAAARQAYAT-- 72 
WP_011748487   1 --mrdhGGDIDkaagl--fgraDWIDLSTGINRRPWQaGP----LSA------HALTALPTAaDTARLSAVAAARFGCP- 65 
WP_122123993   1 -mniqhGGNLDqakklfpevTGSWLDLSTGINPYSYPfSS----LDI------SLYEKLPSYsHEENLRQIAADYYGCKn 69 
3HDO_A        82 PSWIIXANGSDEVLNNLIRAFA---AEgeEIGYVHPSYSYYGTLAEVQGARVRTFGltgdfriAGFPER-YeG--KVFFL 155
WP_083510645  82 PDHVLAGPGTQMLIGLLPILLSrqqRVe-GVRILTPTYSGHETAWAAAGVPITFIPh-----gASLPMPgr---nIVTII 152
WP_083537065 106 PSQVVAVPGTDLALRLLEPIF----HEr-KVAVVRPGYSGHLLAWKHSSVTEATSEs-----lEQAA-----GsnDVIIL 170
WP_014496551  67 SAPIVAMGGAQAAIQLLPQLA----PRg-RARILAPTYNEYAGVLSTAGWDVQEVGe-----lDAL------AgaDLAVV 130
WP_013045446  69 RLTVMAGAGTQAFLQIIPRLV----NVg-TVWIRQPTYNEHAHCWADAGHNIVDG--------DVMP-----DeaDHAVV 130
WP_014457394 106 ASMVVAGGGSQSLIALLPRVL----KAe-RACILGPTYSGHVQAWKQNGISVSEVSt-----fADLQSAaQ-QknTVCIV 174
WP_054540028  67 AAAILPLAGAQAAIQMVPRLR----PPg-HARVLGPTYNEHAASLRAAGWTVDEVGd-----pQAL------AgaELAVV 130
WP_048533724  73 PARILPTHGAQGAIQLVPWLR----PPg-RAAVLSPTYNEHAAALRSAGWPVTPVTt-----aQAA------EgaDLAVV 136
WP_011748487  66 QDQVLPLAGASAAIQLLPHVI----GGr-RAAVLSPTYNEHAASLRAAGWEVAEPAd-----pTAL------AgaDLAVI 129
WP_122123993  70 KFCVALAPGTQILISLMPTVL----NAk-EVYVLYPTYEEYISSWWQAGVKVTRVVn-----fEDFETLcL-QknVVGVI 138
3HDO_A       156 TTPNAPLGPSFPLEYIDELARRCa---GXLVLDETYAEFA-EsNALELVRR-HENVVVTRTLSKSYSLAGXRIGLAIARP 230
WP_083510645 153 CAPNNPTGHVLSAGEIASLAESHghadGVLVIDEAFADFQpV-SAASLLPH--RALIVCRSFGKTYGLAGVRLGFLLGTH 229
WP_083537065 171 ANPNNPDGRTICPDRLRAVAKRLaargGMLVIDEAYADIVpEnSLCTAAS---DGILVFRSFGKFFGLAGLRLGFVVTSR 247
WP_014496551 131 VNPNNPDGRRFAPQDLLALLPRV----GRLVIDESFADAApLlSLASEADR--PGLLVLRSFGKFYGLAGLRLGFALGHA 204
WP_013045446 131 VFPNNPTGDRYT--DLNALASKIerkgGLLIIDGAFLDNAeGaELFADLSD-YSCVIHLRSFGKFFGLAGVRLGFAMTSP 207
WP_014457394 175 CNPNNPDGRLIQASHLLDLANICqavgSWLVVDEAFADITgQ-SVAPALPH--PALLVLRSFGKTYGLPGIRLGFLLAQP 251
WP_054540028 131 VNPNNPDGRETAPARLLRLARQV----GLLVVDESFADPRpAlSLAPSAGR-EQGLLVLRSFGKFYGLAGVRLGFALGHA 205
WP_048533724 137 VNPNNPDGGRLSPERLEQLADTV----GLLIVDESFADPEpAlSVAPRLGAaLANVVVLRSFGKFYGLAGLRLGFALAQG 212
WP_011748487 130 VNPNNPDGREFTPARVAALAATV----GHLVVDESFTDPRpDlSMAGTR---PENVTVLRSFGKFWGLAGLRLGFAIAAP 202
WP_122123993 139 CNPNNPDGRKIDMARLESLIKKWsasgNHLILDEAYMDFSgQ-SMAYLLPS--PGLLVLRSFGKTFGLAGLRVGFLLASP 215
3HDO_A       231 EVIAALDKIRDHYNLDRLAQAACVAALRDQAYLSECCRRIRETREWFTTELRSIGYDVIPSQGNYLFATPPdrDGKRVYD 310
WP_083510645 230 PVLHAMREVMGPWAVNTAGCQIGREALLDTAWRDSMSLRLAHQTQILRHILHDAGLSFVGGTLLFSLWRTA--HAQEIWE 307
WP_083537065 248 HAM-SFRQLIGDWPVCGPAVDIGIAAYRDSHWQSAQRQRLLHAGADLDALLLATGFELKGGTPLYRLVRCA--DADALFR 324
WP_014496551 205 ADIAKLGAASGPWPVSGAAIAIGCRALRDDHWAEATSARLARDCARLDDIVRSLGWRLVGGAPLFRLYETP--DALAAQE 282
WP_013045446 208 TYSDAMRGMLGPWAVNNVALMAGTLALQDDDWIKNHKDVLEQQAAELAKILTNANLSIIGGTFLFQTIRDA--DALSLHE 285
WP_014457394 252 SMAAYARDLLGSWPVSTIGLSVGCQALQDREWLRQASTKLCAASSRLKKMLTKSGLDHKGQAVLFELVECE--RATDLWQ 329
WP_054540028 206 DDIAALSAMAGPWPVSGAAIEIGQAALADRDWARATAARLRAELPRIDALTLRAGWRNVGGTELFRLYATP--DAQAAQA 283
WP_048533724 213 PLATRLAELAGPWPVSGPAIEIASAALTDTGWQQATCRRLAQDAARLDRLAAAAGWPLVGGTPLFRTYAAP--DAQAAQD 290
WP_011748487 203 GLLARLAERAGPWAVGGPALEIGTQALADAQWIDDTVVWLSEAALHLDQIVTLH-WPLVGGTHLFRLYDTP--DAQAAHE 279
WP_122123993 216 EIVQRIRYMLGLWPVNGPALHIAAEALQDGLWKIETEKKLRIQQKRLDAFLQSHFFNLVGGTLLFRLFYHR--SANDIWK 293
3HDO_A       311 GLYARKVLVRHFSDpllAHGXRISIGT-REEXEQTLAALKEI 351
WP_083510645 308 RLAQAGILVRRFAWd--ETLLRFGLPAdEGALTRLTKALTSP 347
WP_083537065 325 RLAMRGILIRPLNEd--SRLVRIGLPAdDDQWTRLYVALQ-- 362
WP_014496551 283 KLARSQIWSRVFARe--PAWLRLGLPGsEAEWTRLAEALAR- 321
WP_013045446 286 HLAKTGIWTRIYREw--PDLMRFGLLRdSTEMDRLHNSIQIW 325
WP_014457394 330 HLCRQGIVTRIFPYn--AHWLRMGLPAsEPQWHRLEEALLDW 369
WP_054540028 284 RLARARIWSRIFPWs--PELIRLGLPGnAAEWARLETALT-- 321
WP_048533724 291 RLAAHHVWSRVFPYs--QQWIRLGLPPaDR-WPQLERAFATV 329
WP_011748487 280 LLARAGIWSRIFPWh--PRWIRLGIPGsREEFDRVAGAFTAp 319
WP_122123993 294 HLASHGIWVRKFDYn--PNWLRFGLLYrQADWQRLEAVLLSi 333
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