HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.
cd00078 is part of a hierarchy of related CD models. Use the graphical representation to navigate this hierarchy. cd00078 is a member of the superfamily cl27008