Conserved Protein Domain Family
MComp1

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pfam20289: MComp1 
ABC-three component (ABC-3C) system Middle Component 1
Middle Components (MCs) of the ABC-3C biological conflict systems occupy the central position between the catalytic effector and ABC ATPases of the systems. MCs are defined by distinctive patterns of conserved charged residues. As some MCs are HTH domains, they are predicted to function akin to kleisins as DNA-binding partners for the ABC ATPases, assisting in recognition and responding to invasive elements such as DNA viruses.
Statistics
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PSSM-Id: 466439
Aligned: 65 rows
Threshold Bit Score: 32.3725
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_036945803             37 SYFLIYNiDCKEfeknedAMKTALETLEIEYSNVDkgrneslkskiqatfdnnqEASQIDKNTSAIYLLQfnnLENLERY 116 Pseu...
GBG56583                 38 YVFSLHLtTEKIll---eTWDFINNIIAVHFQSSL-------------------KKDIERWNIYISFFVAe-eINKDIKY 94 
SFN16380                 33 PTFFINIkDEKNlt---nKWKAITEFIAVHFQSLL-------------------RNEFSIWNIYLFFILEq-eIKDDLKY 89 
PRJNA398646:CJ263_20030  36 HAFFVDIeGYEVle---eSWQQIVNLIAINFQNKL-------------------EKEFERWNIYLFFRLSe-aVDKGLKY 92 
PRJNA272876:SY85_09025   35 SLFIVQVsSNELls---nYWDKISGSIAAYYQPYL-------------------SNDFEKWNIYIMYISTi-kVDQHLKY 91 
SNS61133                 34 SVFVFYFeEESEle---kTWSNVSGNVAGLYQAEL-------------------AEDFDMWNIYMFYLCRs-eLSLALKY 90 
TWJ04948                 37 SLFTLWF-DNEAgl--ekEWDKISGMIAAYYQASL-------------------TDQFTKWNIYVCYLCKt-lISISLKY 93 
WP_071185573             38 PVFFIQFkNLNDle---kFWREFNSFITAEYLIKL-------------------KNDFSKWNSYIFYITDs-sVQRPLKY 94  Flav...
jgilanl:CHU0039          36 IVCMVKFkDETKln---sQWKEFNSYLTAKFIPTV-------------------KDDYSKWNFYVFYFSNn-iVNKSLKY 92 
PJR03557                 33 IFFLEANsDVINe-----NWKRFSNMVAANYQTSEym----------------sNREFDKWNFYIIYISKd-dVSKELKN 90 
WP_036945803            117 rnlvyAIEESPNYFKRYIIPYTKPQVDALNKIISDnygseINTILSDIS 165 Pseudobacteroides cellulosolvens
GBG56583                 95 -----MIEQDKYSTRKLIFDRI-DEPDLIPVI--------IDKKLFSLN 129
SFN16380                 90 -----IIENDTFSSRKIIIYPK-QEVESI-----------IQEHIKNDD 121
PRJNA398646:CJ263_20030  93 -----KIENDTFSCRKIIIDKSESHKSA------------VEDHILNKL 124
PRJNA272876:SY85_09025   92 -----KIENDRFSSRKIVIDQFNKEVNDLT----------IEDLVIDHI 125
SNS61133                 91 -----KIENDRFSSRKIVLDNYEEEISDIGINDI------IDEHITNID 128
TWJ04948                 94 -----KIENDRFSSRKIILDNFSETINDLTLDHI------IRTHITNKD 131
WP_071185573             95 -----EIENNKFSTRKIVIESISQDIDEIL----------LKSILSEHI 128 Flavobacterium commune
jgilanl:CHU0039          93 -----EIENNKFSSRKIVIDNC-ESITATE----------INNVISEHI 125
PJR03557                 91 -----KIENDKFSSRKIVEDLFDKEFNDKEANQLIvk-hiTNTDLEDIL 133
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