Conserved Protein Domain Family
MGC-24

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pfam05283: MGC-24 
Multi-glycosylated core protein 24 (MGC-24), sialomucin
This family consists of several MGC-24 (or Cd164 antigen) proteins from eukaryotic organizms. MGC-24/CD164 is a sialomucin expressed in many normal and cancerous tissues. In humans, soluble and transmembrane forms of MGC-24 are produced by alternative splicing.
Statistics
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Structure
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PubMed ReferencesClick to see Conserved Features Help

pfam05283 is the only member of the superfamily cl27043
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_006013457  25 DCGNFTSCDNCVGRNSEn-RTICLWMSCKgsNDT-----CVNSSV---ANCTAFNVTSMCTANENIttvsPKNT-SSAAT 94 
XP_002925698  63 ICESRNSCVSCFNVSLD--TPTCFWIECK--EKNy----CSPNATv--SDCQVVNGTQFCSAPEPT----PMPT-NSTAK 127
Q2YDH0        65 ICGSRNSCVSCVDG-----NATCFWIECK--GKSy----CSDNSTa--GDCKVVNTTGFCSVPTTT----PTPT-NSTAK 126 cattle
XP_009240404  60 TCEGRNSCVSCFNVSIV--NTTCYWIECK--DESy----CSHNSTv--SDCQVGNTTDFCSVSTAT----PVPTaNSTAK 125
Q9CVT7        21 TCASFNSCVSCVNATFTn-NITCFWLHCQeaNKTy----CANEPL---SNCSQVNRTDLCSVIPPTt---PVPT-NSTAK 88  house mouse
2_pfamImport   1 TCSNKT-CEDCV-------QSSCLWMNCSslVGCy----SSSNAS---DSCSNTSCSEICNVLSKNt---TTPS-TSTST 61 
1_pfamImport   1 ECGSKL-CDTCVQ------NDGCGWFNCTgtLSClnatlLPENGTcirANCSAPVVSTTTAPTSTAq---PTTEiNNINK 70 
EHH14506      53 ACKQLEVCEHCVEGDRArnLSGCVWEQCQpeEPGd----CVAQAEvvkEGCSIYNRSEACPAAHHHptyePKTV------ 122
NP_001258188  53 GCKHLGHCERCVDRAHN--SSICVWQQCGpeEPGh----CVAHTEvvkEGCSVYNHSESCPASHHHsteePKTS------ 120
XP_012661869  60 TCEGRNSCASCTNTSNV--NTTCFWMECK--DKSy----CSHNSTv--SDCQVVNATHFCS-APTTi---PAPT-NSTAE 124 small-eared galago
XP_010598533  58 TCENHQDCASCVNG-----STTCFWLECKeaNKSh----CSHNSTa--SDCHAVNRTESCS-VPTAt---PSPT-SSTAR 121 African savanna...
XP_014322559  57 ICGKHNSCVSCVNASNDiaNISCFWMECKeaGRSy----CSQNSTv--TGCQVVNSTNFCSVPTAS----PLPT-NSTAK 125 little brown bat
XP_006013457  95 ASTTEVTASTNGSVAtmpTSTAkvitspatdkTNSTVMPTTPVAKKSTFDAASFIGGIVLVLGIQAVIFFLYKFCKSKDR 174
XP_002925698 128 TTTLPSSSSTATTTAt--TSGT----------TNTTLTPTSQPGRKSTFDAASFIGGIVLVLGVQAVIFFLYKFCKSKER 195
Q2YDH0       127 TTTLPSTTTTSTTAT---TSGT----------TNTTLSPTIQPTRKSTFDAASFIGGIVLVLGVQAVIFFLYKFCKSKER 193 cattle
XP_009240404 126 PTVQPSPSTTSKTVT---TSGT----------TNTTVTPTSQPVRKSTFDAASFIGGIVLVLGVQAVIFFLYKFCKSKER 192
Q9CVT7        89 PTTRPSSPTPTPSVVt--SAGT----------TNTTLTPTSQPERKSTFDAASFIGGIVLVLGVQAVIFFLYKFCKSKER 156 house mouse
2_pfamImport  62 PFHNSSSTAPSPTSAa--AANA----------STTAVAPTSQP-HKNTFDAASFIGGIVLVLGLQAVIFFVYKFCKSKDR 128
1_pfamImport  71 TRTKPITPTKNG------TTGN----------VTQT-TPITPAPHKNTFDAASFIGGIVLILGLQAVFFFIYKFCKSKDR 133
EHH14506     123 ------------------TTGS----------P---PVPEA---HSPGFDGASFIGGVVLVLSLQAVAFFVLRFLKAKDS 168
NP_001258188 121 ------------------TTGS----------P---PIPED---HSPGFDGASFIGGIVLVLSLQATAFFVLRFLKAKDS 166
XP_012661869 125 NTTLPSSSTTSTVPT---S-GP----------TNTTLTPTSQPIRKSTFDAASFIGGIVLVLGVQAVIFFLYKFCKSKER 190 small-eared galago
XP_010598533 122 TTATPYSTTASTTVPt--S-GT----------ANTTLTPTSQPGRKSTFDAASFIGGIVLVLGVQAVIFFLYKFCKSKER 188 African savanna...
XP_014322559 126 TTTMPSSSTTATP-------GS----------TNTTLSPTSQPTRKSTFDAASFIGGIVLVLGVQAVIFFLYKFCKSKER 188 little brown bat
XP_006013457 175 NYHTL 179
XP_002925698 196 NYHTL 200
Q2YDH0       194 NYHTL 198 cattle
XP_009240404 193 NYHTL 197
Q9CVT7       157 NYHTL 161 house mouse
2_pfamImport 129 NYHTL 133
1_pfamImport 134 NYHTL 138
EHH14506     169 TYQTL 173
NP_001258188 167 TYQTL 171
XP_012661869 191 NYHTL 195 small-eared galago
XP_010598533 189 NYHTL 193 African savanna elephant
XP_014322559 189 NYHTL 193 little brown bat
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