Conserved Protein Domain Family
AroA

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COG0128: AroA 
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]
5-enolpyruvylshikimate-3-phosphate synthase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Statistics
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PSSM-Id: 439898
Aligned: 858 rows
Threshold Bit Score: 164.876
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_077140234   1 MIn-------------Sg------------V--QL--NSPLQ-GEIKIPGDKSITHRAIIFSALAKGQNHIRNPLL-SED 49 
WP_037311224   1 MGek-------------------------nTwaAPtaSERLD-ATVRVPGSKSITNRAFVLAALSAGETLVRNPLD-SRD 53 
WP_036940671   1 MTehvagdr-qtaadpRvtt--------sqGwpAPraRVPLH-ATVHVPGSKSEGNRALVLAALGDGPSTITGLPD-ARD 69 
WP_011096152   1 -------------------------makteMyqPPl-GNRAL-FKMSIPGSKSLTNRHLIIAAIASGETTIHNLLE-SRD 52 
EHR76262       1 MAgqtmgkrwskrwtsSgkghrrndvhalrV--TP--SATLDpiHWALPPSKSHLIRALLLSAQSSQPVELLNVQYaGED 76 
WP_105185260   1 MS----------------------------PaaAPasAGPLS-ASIVVPGSKSATARGYVLAALAAGPSTLTGVLE-ARD 50 
WP_015780658   1 MTdr------------------------iiV------SSAIKpFELRLPGSKYLANRYVVLAAISDGTTRLSNVPR-NDD 49 
WP_011183827   1 Mltd------------------------qhLwnAPraEHLLA-GRVTVPGSKSQTNRALVLAALSDGPSVLEGVLA-SRD 54 
WP_009885384   1 MTdtpdlt-----------------apatgDwlAPvaGGGVT-ATVSVPGSKSLTNRYLVLAALAESNSVIRGWLR-SRD 61 
WP_091810217   1 MPee-------------------------nAwtAPvaLDKID-ATVRVPGSKSITNRAYVLAALSAEPTLVRDPLD-SRD 53 
WP_077140234  50 CMKTMQSFVDLGVTYQID-D-DN---------------------NLVISSPGi---DE-F-KH----KEVTIDLGNSGTS 97 
WP_037311224  54 ARLMLGALDALGAASHAVsD-G-----------------------VRVQPMTd---G----DG-----EVEVALGNAGTV 97 
WP_036940671  70 IRLMIAALRGLGTTIAPGdA-HE----------------------VTVHP------GP-L-HA----ATAPIDCGLAGTV 114
WP_011096152  53 TNLMIEGLRRIGCKIEKLnH-TGthdtgvisphctclndliqpsDVRIIP------SKhY-TC-----STKIDCGLAGTV 119
EHR76262      77 ARAMRRCLQQLGISIDDy-DiEGqrltqvnpv---hfehhpdavKWVVHGAGp---SG-F-KR----PATVLNAGNSGTT 143
WP_105185260  51 TRLMRAALQGFGVRFTDLsD-GV----------------------VRVTP------PErF-------TPHDVHVGLAGTI 94 
WP_015780658  50 ILAALGAIQALGAKVEWL-D-QT---------------------SVEIKGIE----S--FeLA----DDVVIDCHDSGTL 96 
WP_011183827  55 SYLMSAGLQLLGADIQPIgP-GS----------------------VQVMP------G--L-AH----PTGPIECGMAGTV 98 
WP_009885384  62 TLLMVEALKALGADIDEVdG-S-----------------------LHITP------ID-F-SAqregPPITIDCGLAGTV 109
WP_091810217  54 ARLMLGALAALGAESEHTaR-G-----------------------VRVGPFRldqaGE---PA-----ETSIALGNAGTV 101
WP_077140234  98 LRLLTGLFASI--DgL-VVHITGDESLSKRPMKRVIKPLKLMGAKIDAQYHsGddeytLPMTIYG---K-SL-RSiDYEI 169
WP_037311224  98 ARFTPPLAALG--S-R-TVHFDGDPAIRRRPVAPLLQALTDLGADIDDGGR-Gt----VPFTVRG---RgGL-AGgTVEL 164
WP_036940671 115 MRFVPPLAALV--A-G-TTRFVGDDRAAERPIAPLLEGLRQLGAATSSDa--------IPFDLTA---PdEL-TGhEVSI 178
WP_011096152 120 MRFLPVLAGLC--K-G-SVEFFGDDQAIRRPMDGTLHALRKLGVQVDGDr--------IPFTVHG---RgEI-EGgALET 183
EHR76262     144 LRLLGTHAAMI--G-G-PVMLDGDGSLRKRSSAELWGTIEQGGAEVSVGMGeEr----LPALIDGpmdAgRLaSG--IEL 213
WP_105185260  95 MRFVPPLAALA--H-G-ASRFHGDVEAHDRPVAPLLLGLQRAGVSIDHp---Es----LPFTVQG---AgRV-PGgAVTV 159
WP_015780658  97 ARFITALTGLFysSvGhQITITGSQQMRSRPMQESVASLETLGVSIES--EkGf----LPIKISG-----PI-TGgSCEL 164
WP_011183827  99 MRFLPVVAALV--P-G-QTRFVGDEQASRRPIAPVLNGLRQLGVEVDSDr--------LPFSLNA---PdRL-CGpKVTI 162
WP_009885384 110 MRFVPPLAAAT--G-R-EVILDGDAQARVRPMSVIIDALTHLGVSITAED--Nl----LPMTIHA---QsHL-RGgHLEI 175
WP_091810217 102 ARFTPPLAALG--S-R-TVHFDGDEAIRRRPVAPLLSALSALGADIDDDGR-Ga----PPFTVRG---HgGL-RGgPVEL 168
WP_077140234 170 K-EASAQVKSSLIFAGLLNDq--GVTL----YQQAATRNHTEIMVNYLYADHVIvEkvnG-QFKYTVKPINRF-LPLTYS 240
WP_037311224 165 DsSASSQFLSALLLSGPAFErgvTVRLlg-kTPSEPHIAMTMDMLRRFGAAPER-D---G--SEFHVP-PATL-ALSEYT 235
WP_036940671 179 DaSASSQFISGLLLAAAAFPqgiDLMHtganVPSAPHIDMTIAMLARHGVRVAQ-P---ErGRRWVVE-SGMI-RAADER 252
WP_011096152 184 TeHSSSQFISGLLLSACRFKnglTLKHignpLPSRPYIDMTVEVMREWGINVTH-S---D--GVWAVT-PKEL-TGKHIT 255
EHR76262     214 DiSRSSQPMSSWILAAPGLPcevNLQLeg-eAVSSRHAQLSLQLLHMFGGQASN-E---S--GKLSIK-PSTLdQVERYS 285
WP_105185260 160 DaSGSSQFVSGLLLAGARFErglDLRHrggaLPSRPHIGLTVAMLRDRGVAVVE-P---E-PDHWVVA-PGAI-AARDET 232
WP_015780658 165 DaSRSSQFLSGLLIACLKAEkdtLIHLss-dAVSESYVELTLRAIELFGGEVKR-I---N-CREFFIPGQQAL-VAKDIH 237
WP_011183827 163 DsATSSQFISALLLASARFPqgiDLRHdgasVPSTPHIAMTCAMLADRGVTVVS-D---E-PCHWVVR-PGPI-HALDDV 235
WP_009885384 176 DaSASSQFVSGMLLTAPAMPlgiELVNrgetVPSRAHVDMTLEVLADAGVDVTE-P---Q-PEHWIVE-PGLP-RGLDVQ 248
WP_091810217 169 DsSASSQFLSSLLLAGPAFAegiTVRLtg-tVPSEPHIAMTIDMLRRFGADPER-D---G--TTFHVP-ARTL-SLGEYV 239
WP_077140234 241 VPSDVSSAAFIIIHAL-LNkGSNIELNRVGL-NPT--RNAIINYINKvIGNddVISIKNIsvehGetignIIVQyS-S-- 313
WP_037311224 236 VEPDLSSAAPFVVAPL-VA-GGRVHVEGWPS-ETTqpGDRLRSLVRE-LGG--EAVLEGD----G-----LTVT-GtG-- 297
WP_036940671 253 IEPDLTNAAVFLIAGV-IT-GGSVAVADWPR-RSTqpGALIGPVLAR-MGA--AFATGAG----R-----ATAT-HrD-- 314
WP_011096152 256 IEPDLSNAAPFMIGAI-VT-GGSATIQNWPS-KTSqpGKYLEAILPQ-FGA--EITKTAN----T-----ITVS-GtG-- 317
EHR76262     286 IPGDASMAAFSLLACTaL--ARPVELIDWPKaEDAigHEVLHAKAKS-LGI----EW--Ds--------tI-LT-NiD-- 344
WP_105185260 233 IEPDLINAATFLAAPL-LV-GGSVTTA-WPD-HTVqaADAILDVLAA-LGA--EVVRRPG----E-----VTVS-GdG-- 293
WP_015780658 238 VAGDVVSSSYFLAAGL-LA-ESSCTVLNYHF-DSPqgESKFPQVLER-MGA--KVYLKQD----D-----LKVE-YdS-- 299
WP_011183827 236 IEPDLTNAAVFLAAAL-IV-GGSVTVPGWPT-DSTqpGAQFMGIAEK-MGA--IVSRVDG----S-----MTIA-AqGwq 299
WP_009885384 249 VEPDLSNAAAFVAAAL-AT-EGDVTVLDWPA-HTTqaGDGFRSIVEA-FGG--TVTLDRH----G-----LRVQ-GpK-- 310
WP_091810217 240 VEPDLSTAAPFVVAPL-LT-GGTVRISGWPS-TSTqpGAWLRELATD-LGA--EVTLDSG----G-----LTVT-GsG-- 301
WP_077140234 314 NHHG-ITIQKNDIPniiDEIPILSVLLSQSKGESKIEHVNELIVKESNRLAKTIELLEYLNTTYDVIKNGdgditLIInp 392
WP_037311224 298 TVAA-ATLDLHEVG---ELTPVLAALLCFADGPSEIRGVAHLRGHETDRLAALATELSALGGDVTETDDG-----LRI-- 366
WP_036940671 315 DLQG-AELDLRPAS---ELTCSVAALAVAARGTTTIRGVGHIRGHETDRIAAIATELTRVGVDVAELPDG-----LRI-- 383
WP_011096152 318 NITG-IRADLGHIG---ELVPNLVALATLAETPSVFYNIGHIRYHETDRIEALVNEISSLGGTITAGKDY-----IKI-- 386
EHR76262     345 Ae-GpVELDLRDAN---DLLPPLAAVLAFNQG-GVLKGAAHAAYKESNRLNRTAEILHQFGMTAEVTTDG-----LLI-- 412
WP_105185260 294 RVRG-VDLDLSLTS---ELTCVAAALLAVADAPGTISGVAHVRGHETDRLAALETELNALGGRVQQTADG-----LRV-- 362
WP_015780658 300 PLQG-IDVDMGNMP---DVVPTLAALACFAQGETRITNIAHLAFKESNRIVDLCEQLKKLGADCEYDESS-----ITI-- 368
WP_011183827 300 ELRP-LDVDLHEAS---ELTPVVAAVASLARGRSRIRGVAHIRGHETDRLAALEHELAKLGVEVQQTDNG-----LDI-- 368
WP_009885384 311 VLQA-VDLDLSAIG---ELTPVVAALAAMAEGTSRLTGIGHLRGHETDRLSALHRELSAIGIHVVEQPTS-----LTI-- 379
WP_091810217 302 PIQG-QLLDLHEVG---ELTPVLAALLCFAEGPSVLSGVAHLRGHETDRLAALARELTALGGNVTETEDG-----LRI-- 370
WP_077140234 393 dvnEwSSd--Ss----LneyksiKpslqrfikqdkqnneGiYRLQSEHDHRIAMSGYIASSVVNKPIQVIGDECIQTSFP 466
WP_037311224 367 ---H-PA---P-----L------H---------------G-GTFHTYDDHRLVMAGAVLALRVPG-ITVENPATVGKTYP 411
WP_036940671 384 ---E-GM---AgrldqL------Hps------------tGdGLFRCYADHRMAHLGALIGLMVPG-IRLDDVGSTTKTMP 437
WP_011096152 387 ---T-PT---T-----Lt-----R---------------S-GVWKTYKDHRMATSGAIIGLR-HK-LTIEDIECTSKTFP 431
EHR76262     413 ---E-GG---Qsp--tT------P---------------N-RPVETHNDHRLFMTAVLLASKCGGDIVGQTLHLVAD--E 459
WP_105185260 363 ---T-PA---P-----L------H---------------G-GVFHTYADHRMAHAGSLLALAVSG-VELDDLTCTTKTLP 407
WP_015780658 369 ---R-GG---Kq----L------I---------------A-DKVSSCHDHRLAMSLALIGIKLKG-LTIESSEAVAKSFP 414
WP_011183827 369 ---T-GRgadK-----L------H---------------G-GKFGCYADHRMAHAGALLGLVIDG-VELDDITCTSKTMP 416
WP_009885384 380 ---T-GA---N-----P------H---------------S-GLWHTYNDHRMVMAGALLGLRVDG-LVIENADTVAKTLP 424
WP_091810217 371 ---E-PS---P-----L------H---------------G-GLFHTYDDHRLVMAGAVLGLRVAG-VRVENPATVGKTFP 415
WP_077140234 467 TFKEIF-DL 474
WP_037311224 412 GFVSDWeRL 420
WP_036940671 438 DFPGEWdRL 446
WP_011096152 432 RFADLWsGA 440
EHR76262     460 PFLDRLkAA 468
WP_105185260 408 DFAGLWqHL 416
WP_015780658 415 DYWQYLeQI 423
WP_011183827 417 QFPQMWaNL 425
WP_009885384 425 EFTQLWeAM 433
WP_091810217 416 GFVEAWqSM 424
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