Conserved Protein Domain Family
PLN02666

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PLN02666: PLN02666 
5-oxoprolinase
Statistics
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PSSM-Id: 215358
Aligned: 16 rows
Threshold Bit Score: 2040.42
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
303285546   57 SNPPRSRDFRFCVDRGGTFTDVYAEVPDA---ANp----FRTLKLLSEDPANYESAPREGIRRILEEVTG-NAIPRDAPV 128 
168067055    3 FEDRSLRQFRFCIDRGGTFTDVYAEVPAN---PP-----WRTVKLLSVDPANYDDACREGIRRVLEDVTG-DKIPRSAKL 73  
159489757    1 -----MRDFHFSIDRGGTFTDVFAEVPDG---KGg----TKVLKLLSVDPANYPDAPREGIRRVLEEVTG-VCVCSCARD 67  
145347537    1 ----MSGDVKFCIDRGGTFTDVYAEIPRE---GDagevaFVTLKLLSEDPANYASAPREGIRRVLETVHG-REIKRDEKV 72  
219127456    8 TIIPGDGKFHFAIDRGGTFTDIHCRLPNG---DE------IVRKLLSEDPSHYQDAPTEGIRQVLAEFDTeRLYNRGIPV 78  
225440310    1 MDGVNQEKLRFCIDRGGTFTDVYAEIPGQ---SD-----GRVMKLLSVDPSNYDDAPIEGIRRILEEFTG-ESIPRTSKI 71  
255573641    1 MGSIKEEKLRFCIDRGGTFTDVYAEVPGN---PD-----GRVLKLLSVDPSNYDDAPVEGIRRILEEYTG-EKIPRSSKI 71  
255081126    1 MGTTKQRDFRFCIDRGGTFTDVYAEVPDGsppSEgkkssFRTLKLLSEDPANYESAPREGIRRILEEVTG-ETIPRDAPV 79  
302781943   13 LENRSSRHFRFCIDRGGTFTDVYAEVPGE---CG-----FKAIKLLSVDPGNYDDAPREGIRRILEEFTG-KKIPRSEKI 83  
302823413   13 LENRSSRHFRFCIDRGGTFTDVYAEVPGE---CG-----FKAIKLLSVDPGNYDDAPREGIRRILEEFTG-KKIPRSEKI 83  
303285546  129 PTERIEFIRMG----TTVATNALLERDGARSALVVTRGFKDLLEIGNQ-ARPDIFDLKIERPSRLYERVLEVDERARVLD 203 
168067055   74 PTERIDWIRMG----TTVATNALLERKGERTALCITQGFKDLLEIGNQ-ARPKIFDLTVAKPSSLYEEVIEANERVVPAL 148 
159489757   68 VRTGGAWGPLGeggvCTKSEATVAGGAAGRFARMSGKAVQDALKAADEfSRPNIFDLEVRSPHPLYEEVVEVGEQVVLPL 147 
145347537   73 PTERIEWIRMG----TTVGTNALLERKGAATALVTTRGFGDLLAIGNQ-ARPDIFDLAIERPGALYERVVEVDERVRVLG 147 
219127456   79 ETSQIGSIRMG----TTVATNALLERDGARMALLTTKGFEDLLEIGNQ-ARPNIFDLSCAKPSLLYEKTVAIDERLVLAQ 153 
225440310   72 PTDRIEWIRMG----TTVATNALLERKGERIALCVTQGFKDLLQIGNQ-ARPRIFDLTVSKPSNLYEEVIEVEERIELVP 146 
255573641   72 PTDKIEWIRMG----TTVATNALLERKGERIAVCVTQGFKDLLQIGNQ-ARPNIFDLTVSKPSNLYEEVIEVDERVQLVL 146 
255081126   80 PTDRIEWIRMG----TTVATNALLEREGARSALVVTEGFGDLLAIGNQ-ARPDIFDLEIKRPSRLYERVVEAAERVRLFS 154 
302781943   84 PTENIDWIRMG----TTVATNALLERKGERTALCVTKGFRDLLRIGNQ-ARPSIFDLTASKPSPLYEEVVEAEERVRLAL 158 
302823413   84 PTENIDWIRMG----TTVATNALLERKGERTALCVTKGFRDLLRIGNQ-ARPSIFDLTASKPSPLYEEVVEAEERVRLAL 158 
303285546  204 trsrasdreaasaasaaaDDDGAAGGVVVAGVTGEDILVERAIDLEALRPRLQALLDDGIKSLAVVFMHAYAFPNHERAA 283 
168067055  149 ------------------KGVQYRGSNVVQGTSGEMVEIVKPLDLESLTPLLQGLLNKGIRSLAVVFLHSHVYPDHEQAV 210 
159489757  148 --------------------GDSATGSLEAAVTGEVVEVRRRLEEERLRADLQGVLSRGIRSVAVVLKHAAIYPAHERRV 207 
145347537  148 -------------------EGERARGASVVGSTGETVEILKPLDVESLRPRLRALLDDGITSISVVLLHSYTFDEHERAI 208 
219127456  154 f----------------tPDEYRDRYTAHEGVTGETVYVVREPNLTAVRAVLESLKADGITAIAVCLMHAYVYGAHEDMI 217 
225440310  147 nt---------------eEENQDSSASLVKGVSGELLRVVKPLNEEALKPLLKGLLEKGINCLAVVLMHSYTYPEHEISV 211 
255573641  147 dk---------------eEVDQNSSASVVKGVSGELVRIVKPLDEEALKPLLKGLLEKGISCLAVVLLHSYTFPQHELAV 211 
255081126  155 gvdgg---------gsseSEATTEGLKIVTGVTGEAMLVERPLDVESLRPKLQALLDEGIRSLAVVLMHSYAFPDHEAAV 225 
302781943  159 e----------------nDALADEKVEVVQGISGELVEIFRPLDLEALRPSLEGLLEQGIQSLAVVFLHSYIFPRHEQQV 222 
302823413  159 e----------------nDALADEKVEVVQGISGELVEIFKPLDLEALRPSLEGLLERGIQSLAVVFLHSYIFPRHEQQV 222 
303285546  284 GDLARSMG-FERVSTSSELVPMVKIVPRGHTASVDAYLTPCIRTYLDAFLSGFDDGL---KD-VNVSFMQSDGGLTPAGS 358 
168067055  211 ARLAETLG-FKQVSISSALVAMVRAVPRGFTATVDAYLTPVIRLYLSGFLEGFDEGL---KD-VTVSFMQSDGGLTPEHR 285 
159489757  208 GDIAREMG-FEQVCVC------VRMVPRGFTAAADAYLTPHIKRYLAGFVGGFDAGLtaeGGaVQLLFMQSDGGLSPVDA 280 
145347537  209 GALAREMG-FQHVALSSALVPMVRAVPRGHTGSVDAYLTPCIRTYIDSFLDGFDEGL---RD-VKVSFMQSDGGLTPADN 283 
219127456  218 GALAESVGgFEQISLSHRVMPMVKLVSRGHTTCAAAYLTPKITTYLLSFQKGFDANL---AN-VPLTFMKSDGGLAPVHS 293 
225440310  212 EKLAVSLG-FKHVSLSSALSPMVRAVPRGLTASVDAYLTPVIKEYLSGFISRFDEGL---GK-VNVLFMQSDGGLAPESR 286 
255573641  212 ERVAASLG-FRHVSLSSGLSPMVRAVPRGLTASVDAYLTPVIKEYLSGFISKFDEGL---GK-VNVLFMQSDGGLAPESR 286 
255081126  226 GKLAAEMG-FTQVSLSSALVPMVRAVPRGHTASVDSYLTPCIREYLDTFLRGFDDGL---RDgVKVSFMQSDGGLTPAER 301 
302781943  223 EKLAKSMG-FKQVSLSSALVPMVRAVPRGHTATVDAYLTPVIKDYLAGFLSGFDDGL---DK-VIVSFMQSDGGLTPESR 297 
302823413  223 ERLAKSMG-FKQVSLSSALVPMVRAVPRGHTATVDAYLTPVIKDYLAGFLSGFDDGL---DK-VIVSFMQSDGGLTPESR 297 
303285546  359 FSGYKAILSGPAGGVVGFARTTS------GEADGA-PVIGFDMGGTSTDVSRHDGAstgFEQVTETRTAGVTIQAPQLDI 431 
168067055  286 FSGHKAILSGPAGGVVGFARTTF------GLETNQ-PIIGFDMGGTSTDVSRYDGT---YEQVLETQTAGVIIQAPQLDI 355 
159489757  281 FSGHKAILSGPAGGYVGYALTTRw----aGLDLSKlQVIGFDMGGTSTDVSRYAGS---YEHVFETTTAGVTIQAPQLDI 353 
145347537  284 FSGYQAILSGPAGGVVGFALTTSaalrddGDDGRT-PIIGFDMGGTSTDVSRYDPRg-gYEQVTETTTAGVTVQAPQLDI 361 
219127456  294 FGGHQAILSGPAGGVVGYAKTSYk----pGF-----PVIGFDMGGTSTDVSRYDNA---WEHVLETVTAGVAIQAPQLDI 361 
225440310  287 FSGHKAVLSGPAGGVVGYSQTLF------GLETEK-PLIGFDMGGTSTDVSRYAGS---YEQVLETQIAGAIIQAPQLDI 356 
255573641  287 FSGHKAVLSGPAGGVVGYSQTLF------GLETQK-PLIGFDMGGTSTDVSRYAGS---YEQVLETQIAGAIIQAPQLDI 356 
255081126  302 FTGYKAILSGPAGGVVGYAITT-------RAETTQ-PVIGFDMGGTSTDVSRFDAT---YEQVTETETAGVTVQAPQLDI 370 
302781943  298 FSGHKAILSGPAGGVVGYAKTTF------GLETHR-PLIGFDMGGTSTDVSRYAGH---YEQVLETQTAGVIIQAPQLDI 367 
302823413  298 FSGHKAILSGPAGGVVGYAKTTF------GLETHR-PLIGFDMGGTSTDVSRYAGH---YEQVLETQTAGVIIQAPQLDI 367 
303285546  432 TTVAAGGGSKLTFRSGTFRVGPESVGSQPGPVCYRKGGkELSVTDANALLGRVSPAYFPKIFGPTEDQPLDIDAVRRAFE 511 
168067055  356 NTVAAGGGSILKFQAGTFKVGPESVSAHPGPVCYRKGG-QLAVTDANLLLGRVIPDFFPYIFGPNENEPLDLEGTRAAFE 434 
159489757  354 NTVAAGGGSRLIFRNGLFSVGPESVGAHPGPVCYKKGG-SLAITDANLQLGRILPEFFPKIFGPKENEPLDAAGTDAAFR 432 
145347537  362 TTVAAGGGSALTFRSRTFYVGPESVGSQPGPVCYRKGG-ALAVTDANLVLGRILPEYFPKIFGPNEDEALDYESSYKAFE 440 
219127456  362 HTVAAGGGSRLFLKRGMFVVGPESSRAHPGPVCYRKNG-YLAVTDANVVLGRVVPRYFPSIFGPNEDEPLDVDGARAAFE 440 
225440310  357 NTVAAGGGSKLKFQFGAFRVGPESVGAHPGPVCYRKGG-ELAVTDANLILGFVIPDYFPSIFGPNEDQPLDVKATREEFE 435 
255573641  357 NTVAAGGGSKLKFQFGAFRVGPESVGAHPGPVCYRKGG-ELAVTDANLILGFVIPDYFPSIFGPNEDQPLDIEATREEFK 435 
255081126  371 NTVAAGGGSRLTFRSGTFRVGPESVGSQPGPVCYRKGGaNLAVTDANLLLGRVLPEYFPKIFGADEDEPLDAASTRSAFE 450 
302781943  368 NTVAAGGGSKLKFQVGVFKVGPESVGAHPGPVCYRKGG-QLSVTDANLVLGRVIPDYFPSIFGPREDEPLDLEAAKVAFK 446 
302823413  368 NTVAAGGGSKLKFQVGVFKVGPESVGAHPGPVCYRKGG-QLSVTDANLVLGRVIPDYFPSIFGPREDEPLDLEAAKVAFK 446 
303285546  512 AEADTINFELGFdgKDDSKPKLT-PEEVALGYVRVANEAMCRPIREITESKGVETAAHALAAFGGAGPQHACAIARALGM 590 
168067055  435 SLAPTINSYRRE--HDSHSKEMS-VEQIALGFLDVANEAMCRPIRQLTEMKGYETSKHTLACFGGAGPQHACAIARALGM 511 
159489757  433 AVAAEVNAHEAA----TGAPSLSgVDEVAMGFIRVANEAMCRPIRALTQMRGYDAAAHVLACFGGAGGQHACAIARALGM 508 
145347537  441 EVTARINAETGE--------SLS-AEEVAMGFLRVANEAMCRPIREITESKGYEISSHVLAAFGGAGPQHACAIARDLGM 511 
219127456  441 ELTKLPEAQGRS------------AEELAFGFLQVANEAMCRPIRNLTQMKGFDITTHTLACFGGAGPQHACAMAKALGM 508 
225440310  436 KLAKQINSYRKS--QDPSAKDMM-VEEIALGFVNVANETMCRPIRQLTEMKGHETRNHALACFGGAGPQHACAIARSLGM 512 
255573641  436 KLAMQINSYRKS--QDPLAKDMT-IEDIALGFVNVANETMCRPIRQLTELKGHETRNHALACFGGAGPQHACAIARSLGM 512 
255081126  451 AEAQKINRELGL---TGTDQEMS-VEEVALGYVKVANEAMCRPIRQITESKGFDTASHVLAAFGGAGPQHACAIARSLGM 526 
302781943  447 TLADEVNEYRRQ--ADESSVEMS-IEQVALGFLDVANEAMCRPIRQLTEMKGYETSQHALACFGGAGPQHACAIAKALGI 523 
302823413  447 TLADEVNEYRRQ--ADESSVEMS-IEQVALGFLDVANEAMCRPIRQLTEMKGYETSQHALACFGGAGPQHACAIAKALGI 523 
303285546  591 RRVFVHRFCGILSAYGMGLADVVAEAQRPFAASALse--------dgRRAARRASDELRARVVSELAAQGFAM-DDIATE 661 
168067055  512 REVIIHRFCGILSAYGMGLADVVEEAQEPYAAVYSld---------sLAEAKQRANKLAEVATRQLRLQGFRK-DDIKVE 581 
159489757  509 STIFVHRYAGVLSAVGIHLADVVAEVQEPAADKLAap--------eaAAAAGVRQARLKAAAVQKLLDQGFDR-SQITTE 579 
145347537  512 STVFVHRFCGILSAYGMGLADVVAESQAACAAKYEda--------qgLKRAMDDMIALKEKVISQLISDGQFEaSAVRCE 583 
219127456  509 KRVFVHRFGGILSAYGLSLADAVHEEQEPTAETYHgg---------iSESGQTRLQALAEKAQSMLTVQGYDA-SEIVTE 578 
225440310  513 KEVLIHRFCGILSAYGMGLADVIEEAQEPYSAVYGpe---------sLLEATRREVILVKLVRQKLQMQGFRE-ENITTE 582 
255573641  513 KEVLIHKFCGILSAYGMGLADVVEEAQEPYSAVYGhe---------sVLEASSREDVLLKQVKQKLQGQGFRE-ENITTE 582 
255081126  527 STVFVHRFCGILSAYGMGLADVVAETQRPFAGSYPmigggvkgvnpaPADARAAADELAERCLLELVSQGFDReEECECE 606 
302781943  524 REVVVHRYCGILSAYGMGLADVVEDAQEPYAATYGle---------vMAEVSKRARALAQHVTRELKAQNFRD-QDISTD 593 
302823413  524 REVVVHRYCGILSAYGMGLADVVEDAQEPYAATYGle---------vMAEVSKRARALAQHVTRELKAQNFRD-QDISTD 593 
303285546  662 TLLNLRYEGTDTAIMTSGGERRHGAdggdagvdfefdfefefDFDFVAAFGERFRREYGFDLAGsRDVVIDDVRVRGVGS 741 
168067055  582 TLLNLRYEGTDTAMMIREPEDG--------------------SSDFAGAFLKQFRQEYGFELQR-KAILISDVRVHATGI 640 
159489757  580 RYLNLRYHGTDVAVMTAEPAGSRSSsssgss-----sgsssgSSSYGEAFAAAYRREFGFVLD--REVWIDDVRVRAVGR 652 
145347537  584 CFLNLRYDGSDTAMMVPEPD----------------------DGDYAKAFRERFVREYGFDLKG-RALLIDDVRVRGVAN 640 
219127456  579 RFVNMRYEGTDNAIMIQETA----------------------DATLDDSFRALYMREFGFVLQG-RDILIDDYRVRAVVP 635 
225440310  583 TYLNLRYEGTDTAIMVKRQLNEDGV-----------------GCDYAIEFVKLFQQEYGFKLQN-RNILICDVRVRGIGV 644 
255573641  583 TYLNLRYEGTDTSIMVRRHVNEDGS-----------------RYDYAVEFVKLFQKEYGFKLQN-RNILICDVRVRGIGV 644 
255081126  607 VFLNLRYEGTDTAIMVPEPE----------------------DGDFARAFGERFEREYGFKLVG-RDLLIDDVRVRGIGK 663 
302781943  594 LFLNLRYEGTDTTIMIAEPE----------------------DGDFGKAFVREFRREYGFELLN-RKILISDVRVRGTGM 650 
302823413  594 LFLNLRYEGTDTTIMIAEPE----------------------DGDFGKAFVREFRREYGFELLN-RKILISDVRVRGTGM 650 
303285546  742 ASLLTRVPVDVAKDde---pLPEPDSVAEVYFEGGleWTKTPVFLAEALKFKHAIRGPAVVMNGTSTCVIEPGCVASVTE 818 
168067055  641 TNILQPVILDKAKNe-----PQEEGRRHRVYFGSG--WHDTPVYMLEKLLWGHTIPGPAVIMSGNSTILVEPDCKAAITK 713 
159489757  653 A---RPLPDDAAAEaeppgpLPEPLTTTAAFFEPAg-RQPTPAFDLNSLRPGHTLAGPALLIDAISTVVVEPGWRATITG 728 
145347537  641 NSLLTRLPIACCKPg----eKPIANTKTRVYFENLg-WCETPVFQFESLLGGMSIEGPAIIMNGTSTCVIEPICVGHVTT 715 
219127456  636 GATPPQWPSPENIG------APTPIDTTKAYFEHG--WEDVPVYKAEDLLPGHAVKGPSIIVQPISIVVLEIACEALVTA 707 
225440310  645 TNILKPRALEPASG------TPKVEGHYKVYFVNG--WHHTPLFKLENLGYGHVMPGPAIIMNGNSTVIVEPNCKAVITK 716 
255573641  645 TNILKPQVLQPTSG------SPKVEGDYKVYFGNG--WLNTPLFKLENLGPGDIMPGPAIIMNGNSTVIVEPNCKAFVTK 716 
255081126  664 STLLQRVKIPNLSEgkfpgnLPDPDSVARVYFEGG--WREAPVFLLEQLGAGALLEGPCVVMNGTATCIIEPGCVAEVTE 741 
302781943  651 SNILKPLLLDKADSg----dPLAEDRKHRVYFGTG--WHDTRVYLLEKLGYGHELPGPCIVMNGNSTIVVEPNSKAFITK 724 
302823413  651 SNILKPLLLDKADSg----dPLAEDRKHRVYFGTG--WHDTRVYLLEKLGYGHELPGPCIVMNGNSTIVVEPNSKAFITK 724 
303285546  819 FGDLSIDVHptptaereedaetaieeekdeptpEEEEEEEDAYQSPDAVQLSIFNNRFMGIAEQMGRTLQRTSTSTNIKE 898 
168067055  714 YGNVHIEIAaa---------------------qPPATLSRLSMVKADVIQLSIFNNRFMGIAEQMGRTLQRTSISTNIKE 772 
159489757  729 THNIRMDAEepsdp---------------kkkaGAGAAAKAAAAACDPVRLAIFSHRFMGIAEQMGRTLQLTAIEATC-- 791 
145347537  716 YGDLKITVPnv---------------------kEQNETVEADYSRADAILISIFSNRFMGIAERMGRTLQRTSVSTNIKE 774 
219127456  708 TGDLEITVGnch-------------------eqVVEEESSEAQIKEDPVQLSIFAHRFMGIAEQMGRTLQRTAISVNMKE 768 
225440310  717 YGNIKIEIQ------------------------SNLGTVKVAEKVADVVQLSIFNHRFMGIAEQMGRTLQRTSISTNIKE 772 
255573641  717 YGNIKIEIE------------------------SNVNTVQIAEKVADVVQLSIFNHRFMGIAEQMGRTLQRTSISTNIKE 772 
255081126  742 YGDLKIAVDvvkdekskdd-----ekstevvldSSKKDQKDSSKIPDAVQLSIFNNRFMGIAEQMGRTLQRTSVSTNIKE 816 
302781943  725 HGNIKIEVGtsa-------------------asSDDHPSPKVDTKLDVIQLSIFNNRFMGIAEQMGRTLQRTSISTNIKE 785 
302823413  725 HGNIKIEVGtsa-------------------asSDDHPSPKVDTKLDVIQLSIFNNRFMGIAEQMGRTLQRTSISTNIKE 785 
303285546  899 RLDFSCALFGPDGGLVANAPHVPVHLGAMSSTVKWQLDRWNgsderSRLNPGDVLVTNHPS-AGGSHLPDITVITPVF-- 975 
168067055  773 RLDFSCALFSPDGGLVANAPHVPVHLGAMSSTVCWQLQHWG-----QNLKEGDVLVTNHPA-AGGSHLPDITVITPVF-- 844 
159489757  792 -LPPAASLPPPDSALPPN--YAPAILMFLATPSLLMLSCMCrt-taRGLSEGDVLLSNHPQlAGGSHLPDITVITPVGgg 867 
145347537  775 RLDFSCAIFGPDGGLVANAPHVPVHLGAMSSTVSWQLEHWGf----DGLHEGDVLVTNHPR-AGGSHLPDITVVTPVF-- 847 
219127456  769 RLDFSCALFTKNGGLVANAPHIPVHLGAMERAVSFQVEYWNse-grESIKEGEVLVSNHPQlAGGSHLPDITVITPVF-- 845 
225440310  773 RLDFSCALFGPDGGLVANAPHVPVHLGAMSSTVRWQLKYWG-----NNLNEGDVLVTNHPC-AGGSHLPDITVVTPVF-- 844 
255573641  773 RLDFSCALFGPDGGLVANAPHVPVHLGAMSSTVRWQLNYWG-----DNLNEGDVLVTNHPC-AGGSHLPDITVITPVF-- 844 
255081126  817 RLDFSCALFGPDGGLVANAPHVPVHLGAMSETVRWQLKHWAe---nGGLDEGDVLVTNHPR-AGGSHLPDITVVTPVF-- 890 
302781943  786 RLDFSCALFSPTGGLVANAPHVPVHLGAMSSTVQWQLEFWR-----DNLREGDVLVTNHPA-AGGSHLPDITVVTPVF-- 857 
302823413  786 RLDFSCALFSPTGGLVANAPHVPVHLGAMSSTVQWQLEFWR-----DNLREGDVLVTNHPA-AGGSHLPDITVVTPVF-- 857 
303285546  976 RDGECVFLVASRGHHADVGGMTPGSMPPFSRTLADEGAAIKTFKLVEGGVFMEEGITALLTK----PPDG--------SP 1043
168067055  845 KDAILIFFVASRGHHAEIGGITPGSMPPFSKAIWEEGTAIKAFKLVEGGVFQEDGITNILTAgmknTEEEetcdsghmVP 924 
159489757  868 KGKRIVFFVASRGHHADIGGISPGSMPPTSKLLVEEGAAIVSFKIVRQGVFQEEGITQLLLA----PGRLaas--ipgIS 941 
145347537  848 RDGRIVFFVASRGHHADVGGATPGSMPPFSKTIADEGAAIKTFKLVDRGVYQEEGIIKLLTK----PDTG--------SR 915 
219127456  846 HEGKIIFFVASRGHHADIGGIAPGSMPPHSNKLEDEGAMIIAFKLVRDGKFQEEGITEILQSpgklPG----------NS 915 
225440310  845 NNGKLVFFVASRGHHAEIGGITPGSMPPFSKSIWEEGAAIKAFKLVDKGIFQEEGIIKLLQF----PNSDesa---hnIP 917 
255573641  845 DKGKLVVFVASRGHHAEIGGITPGSMPPFSKSIWEEGAAIKAFKLVERGVFQEEGIIKLLKF----PSSNesa---ykIP 917 
255081126  891 RNGELVFLVASRGHHADVGGITPGSMPPFSRTIADEGAAIEAFKLVRGGTYDEEGITALLTS----PSTG--------SP 958 
302781943  858 RDGKIIFFVASRGHHAEIGGITPGSMPPFSKTIREEGAAIKAFKLVEGGVFQEDGIVKILKA----KTLDdget-dtiIP 932 
302823413  858 RDGKIIFFVASRGHHAEIGGITPGSMPPFSKTIREEGAAIKAFKLVEGGVFQEDGIVKILKA----KTLDdget-dtlIP 932 
303285546 1044 GTRKLRDNLSDLAAQVAANQRGIALIDELIDEHGLCKVQAYMRHVQDNAELAVRDTVREYASRLKRERPTASDASdpehR 1123
168067055  925 GTRRIEDNLSDLKAQVAANQRGIALIGELIEQYGLEVVQAYMHHVQANAEEAVREMLKSMAQNVLSQSRAEHDE-----L 999 
159489757  942 GTRNLSDNLSDLKAQVAANTRGIQLVGELIAEYGLGVVTAFMRHIQANAEASVRAMLRQFSERQVRLFAC---------V 1012
145347537  916 GTRKLADNLSDLSAQVAANQRGISLLNELIDECGLGQVQAYMNHVQDNAELAVRDMLKTAAQNVIDNATRLGAQVng-dK 994 
219127456  916 GTRNLRDNMSDLRAQVAANNSGIRLLTELVQEHGLHHVEAYMHFIQKNAEILVRRMLRDFCKEH---------------G 980 
225440310  918 GTRRLQDNLSDLQAQVAANRRGITLIKELIEQYGLDTVQAYMTYVQINAEGAVREMLKSVAARVTSQSPKFGAGD----S 993 
255573641  918 GTRRLQDNLSDLHAQVAANQRGISLIKELIEQYGLDTVQAYMTYVQLNAEEAVREMLKSVAVRVSSESSRFAHNH----S 993 
255081126  959 GTRKLADNLSDLNAQVAANRRGIGLIQELMDEWGERTVTDYMGHVQDNAELAVRDMLREAAERLASRFGTVPGDPs---K 1035
302781943  933 GTRKLEDNLSDLRAQVAANQRGIGLIAELIDEYGLEVVQAYMGHVQANAEAAVREMLKSVAAKHSHKRREDHDHS----L 1008
302823413  933 GTRKLEDNLSDLRAQVAANQRGIGLIAELIDEYGLEVVQAYMGHVQANAEAAVREMLKSVAAKHSHKRREDHDHS----L 1008
303285546 1124 VSLTAEDKMDDGSVVKLTLTLDTRDGSAVFDFTGTSDEVRGNWNAPPAVTTAAVIYCVRCLVNQEIPLNQGCLSPITIVV 1203
168067055 1000 VVLEAEDYMDDGSTIHLKLTIDGRKGEASFDFEGTSPEVLSNWNAPEAVTAAAIIYCLRCLVDVDIPLNQGCLAPVSINI 1079
159489757 1013 GSVTAADIMDDGTPIRLTVTIDRRDGSALFDFEGTGPEVYANHNAPPAVTYSAIIYSLRCLVASDIPLNQGCLAPVTVRI 1092
145347537  995 VTLRALDKMDDGSEVCLTLTLDAAHGTADFDFSGTSPEVSGNWNAPPAVTNAAVIYSIRCLVKQEIPLNQGCLKPVTISV 1074
219127456  981 NRAHAIDFMDDGSPIELTIDIDPNTGSATFDFTGTGPQVLGNHNAPPAVTYSAVIYSLRSLVAEDIPLNQGCLAPITFII 1060
225440310  994 VTIEEEDYMDDGSVIHLKLTIDPHKGEANFDFSGTSPEVYGNWNAPEAVTAAAVIYCIRCLVDVDIPLNQGCLAPVKIHI 1073
255573641  994 ITIEEEDYMDDGSVIHLKLTIDSDRGEAFFDFSGTSPEVYGNWNAPEAVTAAAVIYCLRCLVDVDIPLNQGCLAPVTIHI 1073
255081126 1036 VALAAEDKMDDGSVVRLTLTLDRTEGGAVFDFTGTGGEVLGNWNAPPAVTCAAVIYCVRCLVNQEIPLNQGCLKPIEIII 1115
302781943 1009 VVLEAEDYMDDGSTIKLELTIDSKLGQARFDFAGTSPEVYGNWNAPEAVTAAAVIYCLRCLVDVDIPLNQGCLAPVSIAI 1088
302823413 1009 VVLEAEDYMDDGSTIKLELTIDSKLGQARFDFAGTSPEVYGNWNAPEAVTAAAVIYCLRCLVDVDIPLNQGCLAPVSIAI 1088
303285546 1204 PDGTFLSPNDGAAVVGGNVLTSQRVTDVCFAAFEACANSQGCMNNLTFGDDTFGYYETIGGGAGAGPTWDGASAVQCHMT 1283
168067055 1080 PKGSFLSPSDKAAVVGGNVLTSQRITDVVLTAFQACACSQGCMNNLTFGDATFGYYETIAGGSGAGPTWKGTSGVQCHMT 1159
159489757 1093 PPGCILNPGDTAAVVGGNVLTSQRVTDVVLRAFTAAAASQGCMNNFTFGDEQMGYYETIAGGAGAGPGWTGRSGVHTHMT 1172
145347537 1075 PNGCFLSPSEDAAVVGGNVLTSQRVTDVCLAAFGACANAQGCMNNLTFGDDNFGYYETIGGGAGAGPDFNGASAVQCHMT 1154
219127456 1061 PQNCLLNPSSDAGVVGGNVLTSQRVVDVVLKAFQACAASQGCMNNLTFGDKEFGYYETIAGGVGAGPSWDGPSGVHTHCT 1140
225440310 1074 PLGSFLSPSDKAAVVGGNVLTSQRVTDVVLTAFQACACSQGCMNNLTFGDDTFGYYETIGGGCGAGPSWDGTSGVQCHMT 1153
255573641 1074 PPCSFLSPSDKAAVVGGNVLTSQRITDVVLTAFQACACSQGCMNNLTFGDHTFGYYETIGGGSGAGPTWNGTSGVQCHMT 1153
255081126 1116 PEGSFLSPSETAAVVGGNVLTSQRVTDVCLAAFEACANSQGCMNNLTFGDDTFGYYETIAGGAGAGPAWDGASGVQCHMT 1195
302781943 1089 PKGSFLSPSDKAAVVGGNVLTSQRVTDVVLSAFEACACSQGCMNNLTFGDESFGYYETIAGGSGAGPGWSGSSGVQCHMT 1168
302823413 1089 PKGSFLSPSDKAAVVGGNVLTSQRVTDVVLSAFEACACSQGCMNNLTFGDESFGYYETIAGGSGAGPGWSGSSGVQCHMT 1168
303285546 1284 NTRITDPEIMERRYPVVVRRFAIRNGSGGDGARKGGDGIERAIEFLAPVTVSVLTERRVFAPRGARGGGDGAKGLNTLTR 1363
168067055 1160 NTRMTDPEIFEQRYPVLLHRFGLRANSGGVGKHRGGDGVIRDIEFRKSVTVSILSERRVHAPRGLAGGKDGARGENYLLK 1239
159489757 1173 NTRITDPEILERRYPVVLHAFKLRKGSGGRGCWRGGDGVIRELEALRPLTAGILSERRAVRPFGLCGGGDAEPGLNLLVR 1252
145347537 1155 NTRITDPEILERRYPVILREFSIRQGSGGDGNTKGGDGIVRELEFLKDVTVSVLSERRIFAPKGLAGGNDGARGVNSLRR 1234
219127456 1141 NTRITDPEILERRYPVLLQEFSLRRGSGGRGRHQGGDGVVRELEPLRPLTMSILSERRTLHPYGMAGGEDGACGKNLLVR 1220
225440310 1154 NTRMTDPEIFEQRYPVILHTFGLRENSGGAGLHRGGDGLVREIEFRRPVVVSILSERRVHAPRGLKGGKDGARGANYLIT 1233
255573641 1154 NTRMTDPEIFEQRYPVLLHKFGLRENSGGDGLHKGGDGLVREIEFRRPVVVSILSERRVHAPRGIRGGKDGARGANHLIT 1233
255081126 1196 NTRITDPEILERRYPVVLRRFSLRRGSGGAGEHAGGDGVVREIEFLRPVTVSVLTERRVFAPRGMNGGEDGLMGRNTLMR 1275
302781943 1169 NTRMTDAEIFEQRYPVLLRGFGLREGSGGSGEFRGGDGVVREIEFRRGVTVSVLSERRVHAPRGLCGGGNGARGVNLVLR 1248
302823413 1169 NTRMTDAEIFEQRYPVLLRGFGLREGSGGSGEFRGGDGVVREIEFRRGVTVSVLSERRVHAPRGLCGGGNGARGVNLVLR 1248
303285546 1364 R-RkddggggdgGEEKDIGGKNTVTVCAGDVLTIRTPGG----GGYGEKT 1408
168067055 1240 T-D---------GRRLFLGGKNTVRVKAGERLQILTPGG----GGWGSPD 1275
159489757 1253 A-G---------GRTVNLGAKATVHLEAGDRLRILTPGGeggdGGEGGES 1292
145347537 1235 V-N---------GEVVDLGGKNSVQVSAGDVLRIETPGG----GGYGTKM 1270
219127456 1221 K-D---------GITVNMGGRCSSSINTGERLRIETPGG----GGYGAFP 1256
225440310 1234 K-D---------KREVYLGGKNTVAVQAGEILRILTPGG----GGWGSLF 1269
255573641 1234 K-D---------KRKIYLGGKNTVEVQAGEILQILTPGG----GGWGS-- 1267
255081126 1276 AlD---------GKEVNLGNKNSVKVRAGDLLRIATPGG----GGFGAKP 1312
302781943 1249 K-D---------GRCVNLGGKNTVRVEAGEVLRILTPGG----GGYGGAP 1284
302823413 1249 K-D---------GRCVNLGGKNTVRVEAGEVLRILTPGG----GGYGGAP 1284
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