Conserved Protein Domain Family
COG3920

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COG3920: COG3920 
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms]
Statistics
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PSSM-Id: 443125
Aligned: 911 rows
Threshold Bit Score: 102.676
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AAM06739      857 T-ERKE----AERTL-----DKI--QIA-------------RQKEIHHRIKNNLQVISSLLDLQAGKFnnkehiR-DSE- 909 
WP_088870745  364 A-RVAD----RTRHLdr--aLAE--REM-------------LLRDTHHRVKNNLQVVSSLLQLQAG--------M-NPA- 411 
WP_080517612  329 E-IVTE----RTRALrs--tLAR--NEM-------------LLREVHHRVKNNLQLISSLVALQRRGV------Q-EPA- 378 
WP_076000333  804 AdEMHAladtIRDELqe--sQEL--QDG-------------LVHSAYRHNVETIALIKQLTAVTGKSA------G-DEHl 859 
WP_011447513  351 SpESRDdae---------pgTETg-SES---------------REVRHTYITLLQIVRNVLSQKFlSI------AaEPEh 399 
WP_083777599   69 lyEKRQy------FMpggrmTAN--AEV-------------RIATLERRLTGSYTLLQALLGIRLRSV------S-DPE- 119 
WP_075798280    6 Sdps------lipSLtr--mMHRprHDAgd----------dALRQLRHHSKNALQRILAQLWHSEDLQ------A-TPE- 59  
WP_013258184    1 --------------------MSQ--HDLdgpppqwppdcaaVARTVCHRVKNDLQMLMNLLVLAEAGA------G-TPQ- 50  
WP_003603123  141 H-ALAA----ERDRTqv--aLDA--NAL-------------LLREIGHRARNDLQMISAMLTLQSGNS------A-DPA- 190 
WP_014493261  699 S------------ERkq--aETQ--QRL-------------LLNELNHRTKNNMQMLQGLLYTAARSA------R-SEE- 741 
AAM06739      910 -VLEAFKESQDRVT--SIALIHEELHeeEGKTTD-TLNFPIYLQRLVKNLFRTYTl------gNIDI-SLNLD-LkeNIF 977 
WP_088870745  412 -LRPALNDALRRIH--AMGILHEQLH--HASDVD-VVQLDRVITALTCEVDNIHQgeghaaggPRRV-SVVLD-Lt-PLE 482 
WP_080517612  379 -MRERMARIQGQIG--AIAKTYDLLH--QFGASE-TVDFGPFVPALCAAIEGAEGg-------RARI-EAELQg---SAQ 441 
WP_076000333  860 ---------PGHLA--AMEVLQKSYYf-Q-NA-ElTVNLHEYVDGLCNLLLPRAAv------dPATItTINL--At-SSL 916 
WP_011447513  400 dMR------YGKILleAILQLYEA----GGGRGA-GVHLCKYIRLIIGCITEDFAee------mQDI-EIVIScAi-DDA 460 
WP_083777599  120 -SRRHLTWLSDVVA--AMGLLNRRMT--DE---G-PVDFAAYLNDATAFWRRVGE--------ARGV-RIDVR-Aa-EAL 179 
WP_075798280   60 -GRRLVRDLENRIS--LSAGISDDLF--GfTR-EpR-PLDERLRSLCEKVVGLMAd------pDQRI-ALTLQ-I--DGA 122 
WP_013258184   51 ---ELSEAVQKRLS--ALGAVYTLIA--DEGR-Q-P-TAQALAREVARRVLARHGl---------Ap-AINTE-Gd-PLP 108 
WP_003603123  191 -VRAALGEAIGRID--ALSTLYRQSA--PPEESA-GHDLGDLVREIAETLVEASG--------RRDI-ALALD-La-PLR 253 
WP_014493261  742 -ARRVLDDACSRIA--AMAAAQRVLY--GTTDAT-SFAADEFLGAVVETIQQTLP---------ARI-KITRT-Qa-TGA 803 
AAM06739      978 FDMDTAVPLGIIVNELVSNSLKHAFSGRNKGI-IQIKLF------Seeagnepnskrklsmeklikeklaeeelaeeela 1050
WP_088870745  483 SDLTASVPVTLVLNEVLSNAFKHAYPEGRAGT-LAVTLR------R---------------------------------- 521 
WP_080517612  442 VSADSAIALSLALNELVTNALKHAGPT---PR-IRVSCG------R---------------------------------- 477 
WP_076000333  917 IPVQIATPLAIILYELLDNAMQHGFPDASPANfIQVSAEikpstsQ---------------------------------- 962 
WP_011447513  461 IGEKHAAILGIITGEVILNAIRHAFTPGQPGR-IELSLR------R---------------------------------- 499 
WP_083777599  180 LPETHALPLAIIVHEVMSNAVRHAFPERERGS-IAVAYS------R---------------------------------- 218 
WP_075798280  123 CPDHLENVVLRIAHEMVGNAVKHGLHVRLSGR-ITVEFG------W---------------------------------- 161 
WP_013258184  109 LSLRLCSPLALWLGEVIDNAVCHGRAADGAAR-LAFLAG------R---------------------------------- 147 
WP_003603123  254 VRPEAAGPLALIVNEVVSNAVRHAFPS-RAGR-LTVRIA------R---------------------------------- 291 
WP_014493261  804 LSNDIAMPLALILNELLTNAAKHGIRDPAADS-IRVSLV------E---------------------------------- 842 
AAM06739     1051 keelakeripgKSTGYTLIVSDDGIGI-PeEIDIKNPETLGLQLVNILV-DQLDGKIKLER-E-HGTEFIINFS---VE 1122
WP_088870745  522 -----------EGDEGVLTVADDGVGM-PdTATGTGRKSLGLLLIDAFT-RQLRGSFLYEAtT-PGTRFTLRFP---LG 583 
WP_080517612  478 -----------EGDALVLRVEDDGPGL-PeGFDLTAQAGFGVRMVAGLI-GQAGGTIRTLAtE-GGAAFEIRVP---VT 539 
WP_076000333  963 -----------APDVLTITVQDDGVGLsP-GLTVQSARSHGFMVVNALT-QRLNGNIDVEl-G-KGTTISVSLPl--IE 1024
WP_011447513  500 -----------EEDWYIYQVQDSGRGF-PeSIiRTGSATSGFTIIENLA-LELSGTMTLAN-D-GGAVVRVIFP---AA 560 
WP_083777599  219 -----------ASDGVSLVIRDTGVGT-Da-LT-P---RDGLALVQGLV-EHLGGTLAIETaAgAGVGVRVRLP---IA 276 
WP_075798280  162 -----------RGQGWQLRVTDDGWG--P---SPGAVDGDGMQLMRSLS-EPYGGRIVMSRqD-STTGVTLDLP---AA 219 
WP_013258184  148 -----------DDDETWLAVGDAGPGL-PpRFDIEAHAGLGLRLAMAVAqRDLGGAMTLHS-ErGGVTARLCVPereFR 213 
WP_003603123  292 -----------DGADVTVAVEDDGIG--P---SATGDGSFEATLIDVLS-RQVGGTICVRPrDpAGTAIELRFP---AE 350 
WP_014493261  843 -----------HDGQFELHVEDDGPGF-D--LNAVRQTSSGLRLVLGLA-RQLHAELAVSR-S-P-SRATLRFg---AS 900 
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