1OX4


Conserved Protein Domain Family
hisF

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TIGR00735: hisF 
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imidazoleglycerol phosphate synthase, cyclase subunit
[Amino acid biosynthesis, Histidine family]
Statistics
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PSSM-Id: 273241
Aligned: 11 rows
Threshold Bit Score: 388.647
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1OX4_A       238 GLTRRIIACLDVRtndqgD-----LVVTKGDQYDVreksdgkgVRNLGKPVQLAQKYYQQGADEVTFLNITSFRDcplKD 312 baker's yeast
P10373         1 MLAKRIIPCLDVR-----D-----GQVVKGVQFRN--------HEIIGDIVPLAKRYAEEGADELVFYDITASSD---GR 59  Escherichia coli
P44436         1 MLAKRIIPCLDVR-----D-----GQVVKGVQFRN--------HEIIGDIVPLAQRYAQEGADELVFYDITASSD---GR 59  Haemophilus inf...
O34727         1 MITKRIIPCLDVK-----E-----GRVVKGIQFLE--------LKDAGDPVELAEVYDREGADELVFLDISASHE---GR 59  Bacillus subtil...
P74106         2 TLAKRILPCLDVN-----A-----GRVVKGINFVD--------LQDAGDPVELARAYNEAGADELVFLDITATHE---QR 60  Synechocystis s...
O53908        12 GLAVRVIPCLDVD-----D-----GRVVKGVNFEN--------LRDAGDPVELAAVYDAEGADELTFLDVTASSS---GR 70  Mycobacterium t...
O66567         1 MLAKRIIPCLDVD-----K-----GRVVKGVKFLN--------LRDAGDPVEVAKRYEEEGADELVFLDITASAE---DR 59  Aquifex aeolicu...
O29439         1 MLAKRIIPCLDVT-----Lde-seARVVKGVEFVN--------LRDAGDPVELAKRYDEEGADELVFLDITASPE---GR 63  Archaeoglobus f...
Q57854         1 MLTKRIIPCLDIK-----D-----GRVVKGTKFLN--------LRDAGDPVELAQYYDDEGADELVFLDITASAE---KR 59  Methanocaldococ...
WP_010876956  28 MLAKRIIPCLDCD-----Lqv-pnGRVVKGVEFKQ--------IRYAGDPVELATRYYEDGADEIVFLDITASHE---RR 90  Methanothermoba...
P33734       235 GLTRRIIACLDVR-----TndqgdLVVTKGDQYDVreksdgkgVRNLGKPVQLAQKYYQQGADEVTFLNITSFRDcplKD 309 Saccharomyces c...
1OX4_A       313 TPMLEVLKQAAKTVFVPLTVGGGIKDIVDVDgtkipalevasLYFRSGADKVSIGTDAVYAAEKYYELGNRgdgtspiet 392 baker's yeast
P10373        60 VVDKSWVSRVAEVIDIPFCVAGGIKSLEDAA-----------KILSFGADKISINSPALADPTLITRLADR--------- 119 Escherichia coli
P44436        60 TVDKSWVERIAQVIDIPFCVAGGIKTIEDAE-----------KLFAFGADKISINSPALADPTLISRLADR--------- 119 Haemophilus inf...
O34727        60 KTMVDVVEQVAAKLAIPFTVGGGINQLSDMK-----------TILRAGADKVSVNTAAVLRPELITEGAEF--------- 119 Bacillus subtil...
P74106        61 DTIIDVVYRTAEEVFIPLTVGGGISTLEHIK-----------NLLRAGADKVSVNSSAVRDPDFISRASDR--------- 120 Synechocystis s...
O53908        71 ATMLEVVRRTAEQVFIPLTVGGGVRTVADVD-----------SLLRAGADKVAVNTAAIACPDLLADMARQ--------- 130 Mycobacterium t...
O66567        60 EIMIDVVKKVAETVFMPFTVGGGIRSLEDMR-----------RLLEAGADKISINTAAVKNPNLIYEGAKR--------- 119 Aquifex aeolicu...
O29439        64 RTMIDVIERTAEQVFIPFTVGGGIKSIEDIN-----------TILSAGADKVSINTAAVKNPEFVREAADI--------- 123 Archaeoglobus f...
Q57854        60 DIIIDVVERTAEKVFIPLTVGGGIKSIEDFR-----------RILRAGADKVSINTAAVKNPNLIKEASEI--------- 119 Methanocaldococ...
WP_010876956  91 ETMTHVIEATTENVFVPICVGGGIRKPEDYF-----------KMLKAGADKCSTNTAAIKNPELINEASDL--------- 150 Methanothermoba...
P33734       310 TPMLEVLKQAAKTVFVPLTVGGGIKDIVDVDgtkipalevasLYFRSGADKVSIGTDAVYAAEKYYELGNRgdgtspiet 389 Saccharomyces c...
1OX4_A       393 iskaYGAQAVVISVDPKRVYVNsqadtknkvfeteypgpngekyCWYQCTIKGGRES----RDLGVWELTRACEALGAGE 468 baker's yeast
P10373       120 ----FGVQCIVVGIDTWYDAET----------------------GKYHVNQYTGDESrtrvTQWETLDWVQEVQKRGAGE 173 Escherichia coli
P44436       120 ----FGVQAIVVGIDSWFEQET----------------------GKYWVNQYTGDETrtrqTHWQLLDWVKEVQQCGAGE 173 Haemophilus inf...
O34727       120 ----FGSQCIVLAIDAKYDKESd----------------------TYKVYTHGGRKK----TDWEVTAWAKEGVKRGAGE 169 Bacillus subtil...
P74106       121 ----FGRQCIVVAIDARRRLDAd--------------------nPGWDVYVRGGREN----TGLDAIAWAEEVAKRGAGE 172 Synechocystis s...
O53908       131 ----FGSQCIVLSVDARTVPVGsap-----------------tpSGWEVTTHGGRRG----TGMDAVQWAARGADLGVGE 185 Mycobacterium t...
O66567       120 ----FGSQCIVVAIDAKRKG------------------------NSWEVYIHGGRTP----TGLDAVEWAKKVESLGAGE 167 Aquifex aeolicu...
O29439       124 ----FGSQCIVVAIDCRRNFDLskgeyiv--------eledgtkAWYEVVIYGGRKP----VGIDAVWWAKRVEELGAGE 187 Archaeoglobus f...
Q57854       120 ----FGSQCVVVAIDAKRHYVNedeidkink----nvvkvedgyCWFEVYIYGGRKE----TGIDAINWAKKVEELGAGE 187 Methanocaldococ...
WP_010876956 151 ----VGSQACVVAIDAKRRYIenpresder-----fiievddgyCWYECSIYGGREF----TGIDAVKWAMECQDRGAGE 217 Methanothermoba...
P33734       390 iskaYGAQAVVISVDPKRVYVNsqadtknkvfeteypgpngekyCWYQCTIKGGRES----RDLGVWELTRACEALGAGE 465 Saccharomyces c...
1OX4_A       469 ILLNCIDKDGSNSGYDLELIEHVKDAVKIPVIASSGAGVPEHFEEAFLKTRADACLGAGMFHRGEFTVNDVKEYLLEHGL 548 baker's yeast
P10373       174 IVLNMMNQDGVRNGYDLEQLKKVREVCHVPLIASGGAGTMEHFLEAFRDADVDGALAASVFHKQIINIGELKAYLATQGV 253 Escherichia coli
P44436       174 IVLNMMNQDGLRNGYDLAQLKLVRGVCRVPLIASGGAGKMVHFRDAFIEAKVDGALAASVFHKQIIEIGELKSYLVQSAI 253 Haemophilus inf...
O34727       170 ILLTSMDSDGEKKGFDHTLTKLVSEAVPVPVIASGGAGNAQHMLEAFTKGEADAALAASIFHYKETSIKEVKSYLKEYGV 249 Bacillus subtil...
P74106       173 LLVTSMDGDGTQAGYDLALTAAIAERVEIPVIASGGAGNCQHVYEAFTEGKAEAALLASLLHYGQLTIGELKTFLEARQI 252 Synechocystis s...
O53908       186 ILLNSMDADGTKAGFDLALLRAVRAAVTVPVIASGGAGAVEHFAPAVAAG-ADAVLAASVFHFRELTIGQVKAALAAEGI 264 Mycobacterium t...
O66567       168 ILLTSMDRDGTKDGYDIELNRAISEAVNIPVIASGGAGKKEHFYEVFSKTKVEAALAASVFHFREISIPELKEYLLERGI 247 Aquifex aeolicu...
O29439       188 ILLTSMNRDGTKDGFDIPITRKISEEVNIPVIASGGAGTKEHFYEGFVEGKADACLAASIFHYREIGIREIKEYLAERGV 267 Archaeoglobus f...
Q57854       188 ILLTSIDKDGTKSGYDLILTKEISKSVKLPVIASGGCGKPEHVYEAFVYGKADAALMAGILHYREYTIEEIKKYCADRGI 267 Methanocaldococ...
WP_010876956 218 ILLTSMDRDGTKMGYDIPLTRTMSENLDIPVIASGGVGEPEHIYEAFTDGKADAALAASIFHFNEYPVPAVKEYLRSRGV 297 Methanothermoba...
P33734       466 ILLNCIDKDGSNSGYDLELIEHVKDAVKIPVIASSGAGVPEHFEEAFLKTRADACLGAGMFHRGEFTVNDVKEYLLEHGL 545 Saccharomyces c...
1OX4_A       549 KVR 551 baker's yeast
P10373       254 EIR 256 Escherichia coli
P44436       254 EIR 256 Haemophilus influenzae Rd KW20
O34727       250 NVR 252 Bacillus subtilis subsp. subtilis str. 168
P74106       253 PVR 255 Synechocystis sp. PCC 6803 substr. Kazusa
O53908       265 TVR 267 Mycobacterium tuberculosis
O66567       248 NVR 250 Aquifex aeolicus VF5
O29439       268 QVR 270 Archaeoglobus fulgidus DSM 4304
Q57854       268 PMR 270 Methanocaldococcus jannaschii DSM 2661
WP_010876956 298 PIR 300 Methanothermobacter thermautotrophicus
P33734       546 KVR 548 Saccharomyces cerevisiae S288c
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