Conserved Protein Domain Family
SDH_sah
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pfam01972: SDH_sah 
Serine dehydrogenase proteinase
This family of archaebacterial proteins, formerly known as DUF114, has been found to be a serine dehydrogenase proteinase distantly related to ClpP proteinases that belong to the serine proteinase superfamily. The family has a catalytic triad of Ser, Asp, His residues, which shows an altered residue ordering compared with the ClpP proteinases but similar to that of the carboxypeptidase clan.
Links
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Statistics
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PSSM-Id: 110924
Aligned: 4 rows
Threshold Bit Score: 474.334
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
O66996   1 MPYYDPFSY-LFSLLWFLLFVFILLSPWYKRMALIKAREDVIRKLEEKRKSRVITMIHRQEQIGFLGIPIFRFMTIEDSE 79  Aquifex aeolicus
Q57601   3 GEKMDPLSGfISSLIWWLLFFYLIMAPQIQYKQLQLARLKILRELSNKRNSTVITMIHRQESIGLFGIPVYKFITIEDSE 82  Methanocaldococcus ja...
O29403   7 VTYSDPMAS-LSGLFWILLFLYLIFAPQLKHQQLLAARRRAMRRIGMKRGSNVITMIHRQESIGFLGIPIYRFIDIDDSE 85  Archaeoglobus fulgidus
Q58890   9 KIMGDEMTS--MDMFFFLFIFLLFIYPEMMMRYRIMKRLRCIREIERQRGTRVIAMIHRQEALTFLGIPIYKFITIEDSE 86  Methanocaldococcus ja...

O66996  80 RVLRAIRMTPDDMPIDLIIHTPGGLALAATQIANALVKHKAPVRVIVPHYAMSGGTLIALAADEIIMDENAVLGPVDPQI 159 Aquifex aeolicus
Q57601  83 EILRAIRAAPKDKPIDLIIHTPGGLVLAATQIAKALKAHPAETRVIVPHYAMSGGTLIALAADKIIMDENAVLGPVDPQL 162 Methanocaldococcus ja...
O29403  86 KVLRAIRSTPKDKPIDLIIHTPGGLVLAATQIAKALHDHPAKTTVIVPHYAMSGGTLIALAADEILIDPHAVLGPVDPQL 165 Archaeoglobus fulgidus
Q58890  87 EILRAIRLTPEDMPIDLIIHTPGGLALASEQIALALKEHKAKTTVIIPHYAMSGGSLIALAADEIIMDKNAVMGPVDPQI 166 Methanocaldococcus ja...

O66996 160 GNMPAASILKVLEKKDPKDIDDQTLIMADVSEKAIKQMVDCLVDLLtKNGMDKEKAKKIAEELATGKFTHDYPLTVEYLK 239 Aquifex aeolicus
Q57601 163 GQYPAPSIVKAVEQKGADKADDQTLILADIAKKAINQVQNFVYNLL-KDKYGEEKAKELSKILTEGRWTHDYPITVEEAK 241 Methanocaldococcus ja...
O29403 166 MNYPAPSILKVVEKKEPKDIDDKTLIMADIAEKAINQVRETVFNLL-KDKMDEEKAREVAKILTEGRWTHDYPLTVEELR 244 Archaeoglobus fulgidus
Q58890 167 GQYPAASILEAYYRKG-EKVSDETLILVDISKKAIKQMEEFVYELL-KDKYGDEKAKEIAKKLTSGTWTHDYPLTVSKLK 244 Methanocaldococcus ja...

O66996 240 SLGLPVNTNVPQEVYELMELYEQPMGSQPPsVQYIPVPYKspqQQQNAK 288 Aquifex aeolicus
Q57601 242 ELGLDVDTNVPEEVYTLMELYKQPVRQRGT-VEFMPYPVK---QENGAK 286 Methanocaldococcus jannaschii DSM 2661
O29403 245 QLGLKVSTDVPEEVYELMELYPQPMMQRHPgVEFVPSPPK---GEKPSF 290 Archaeoglobus fulgidus
Q58890 245 ELGIEVNTNVPRKVYELLELYPQPMGAKPS-VYYIPVPYSkkeSEKNAK 292 Methanocaldococcus jannaschii DSM 2661
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