Q29GI5            2 EVEYEDSG--WQGRAK--------AQSNSEEVhEDNPQKTIQECLEKFLTPDYIMEPGIFTQLKRYFQSGGSPEEVISML 71  Drosophila p...
XP_011252244      2 ESDYDEDRsgWGDEMNr------sDDCSGEDT-FDNPQEVLNECLDKFKTPDYIMEPGIFAQLKRYFQAGGNPEQVIELL 74 
OWR53707          2 PSQYDEERv-WEGQNQnh-----yEDDGTEDV-IDNPEEVLQECLEKFKTPDYIMEPGIFGQLKRYFQAGGNPEQVIEQL 74 
EFA00603          2 DEEYDERN--WDTVDRld-----nDSDAGDET--ENPEQVLKECAEKFSTSDYIMEPGIFSQLKRYFQSGGNPLQVIEEL 72 
XP_001944110      2 EDDYDEYRr-WDGDVDv-------EADDNDDI-LENPEETLTQCLEKFSSADYIMEPGIFSQLKRYFQVGGTPEHVIELL 72 
EFX85644          2 dDGYDNQD--WGESSGmrgdsemgDSDNEDQY-MENPAEVLEECLQTFKTQDYIMEPGIFNQLKRYFTVGGSPAHVIELL 78 
Q922L6           11 GEDYFGNAseWGEEADggq---hqEDDSGEG---EDDAEVQQECLHKFSTRDYIMEPSIFNTLKRYFQAGGSPENVIQLL 84  house mouse
EDV25448          8 DNEYESYY-----NAGdfqeeqpdNDHNADD---EDTMTVIEECKRKFSNDDSVMESDLIVHIRKYIKAGGTPEELVQLL 79 
jgi:OSTLU_93007   2 SDDDEVCT--RTATASdgegtragESGAIAAL-GETKTSRLMELEARLAEKDFIMEPSAIDDVRAYVSAGGAPSTAIELL 78 
XP_002431657      2 EDDYDEDKg-WEGDGGd------gDSEGGEEA-LENPQEVLTECLEKFSTPDYIMEPGIFTQLKRYFQAGGNPEQVIDLL 73 
XP_310712         2 EEEFEDEA--WNNSAGrgna-peeEVENHEEP-SENPKAVVSDCLQLFSSVDYIMEPGIFVQLKRYFQAGGTPEQVINTL 77  Anopheles ga...

Q29GI5           72 SENYKAVAQMANLLAEWLILA-----GVKVTDVQAMVENH---------------------------------------- 106 Drosophila p...
XP_011252244     75 SKNYTACAQMANLLAEWLILA-----GVKVTDVQAMVENN---------------------------------------- 109
OWR53707         75 SINYNAVAQMANLLAEWLILG-----GVKVTEVQAMVENH---------------------------------------- 109
EFA00603         73 SQNYTAVAQMANLIAEWLITG-----GVNVTSVQAMVENH---------------------------------------- 107
XP_001944110     73 SKNYIGVAQMANMVAEWLILG-----GVAIGEVQSFVENH---------------------------------------- 107
EFX85644         79 SQNYSASAQMANLMAEWLILA-----GATINDVQSMVENH---------------------------------------- 113
Q922L6           85 SENYTAVAQTVNLLAEWLIQT-----GVEPVQVQETVENH---------------------------------------- 119 house mouse
EDV25448         80 SDHYIGEGEVANAYIKWLQDL-----GVKDETINRTCVEH---------------------------------------- 114
jgi:OSTLU_93007  79 SENYRGYAAMTTLAVHWLKVTapprrGANTSPIKVSAAVEtrgidngdgdatrtptggiltsgagkgtpreraatmetea 158
XP_002431657     74 SQNYSATAQMANLLAEWLISG-----GVNVTAVQAMVENH---------------------------------------- 108
XP_310712        78 SANYTAVAQTANLLAEWLIMA-----GVRVTDVQAMVENH---------------------------------------- 112 Anopheles ga...

Q29GI5          107 -------LKEMILKSFDPKKADTIFTEEGETPDWLTEMIDHYTWRSLIYRLAEEYPDCLMLNFTIKLISDAGFQSEITSI 179 Drosophila p...
XP_011252244    110 -------LKDMILKTFDPKKADKIFTEEGETPAWLTEMIQHPTWRSLIYRLAEEYPDCLMLNFTIKLISDAGFQGEITSI 182
OWR53707        110 -------LKDMILKTFDPKKADTIFTEEGETPAWLTEMIEHPTWRSLIYRLAEEYPDCLMLNFTIKLISDAGFQGEITSI 182
EFA00603        108 -------LKEMILKTFDPKKADTIFTEEGETPAWLTQLIEHPTWRSLIYRLAEEYPDCLMLNFTIKLISDAGFQAEITSI 180
XP_001944110    108 -------LKDMVLKTFDPKKADTIFSEEGETPAWLTEMIEHKIWRSLIYRLAEEYPDCLMLNFTIKLISDAGYQGEITSI 180
EFX85644        114 -------LKEMIIKMFDPKKADTIFTEEGETPAWLTEMIEHPTWRSLVYKLAEEYPDCLMLNFTIKLISDAGFQGEITSI 186
Q922L6          120 -------LKSLLIKHFDPRKADSIFTEEGETPAWLEQMIAHTTWRDLFYKLAEAHPDCLMLNFTVKLISDAGYQGEITSV 192 house mouse
EDV25448        115 -------LREVVISKFDPAKADSLFIGEGKNVTWLQDMIAQPFWRNLFYCLAERFPDCLVCKFAVRLISDAGYQDDINNI 187
jgi:OSTLU_93007 159 rfdemyfLEALVREKFDANKADAVF--QGRPPAWLDGLFKSERGRAVLFSLAERNPNCLLISCAIQHAWQRGMRHEVRAL 236
XP_002431657    109 -------LKDMVLKTFDPKKADTIFTEEGETPAWLTEMIEHPTWRSLIYRLAEEYPDCLMLNFTIKLISDAGFQGEITSI 181
XP_310712       113 -------LKDMILKTFDPKKADKIFTEEGETPGWLTEMIEHHTWRSLIYRLAEEYPECLMLNFTIKLISDAGFQSEITSI 185 Anopheles ga...

Q29GI5          180 S-TAAQQIEVFSRVLKTSIVKFLNNPDDVHGA---IQECARMVCHGQHTYVYSQVLIQVLSQEQKGGFN------MKRLS 249 Drosophila p...
XP_011252244    183 S-TAAQQIEVFSRVLKTAIAGFLENTENWQSS---IQECAKMVCHGQHTYVYSQVLLQILAQESRGGFM------MKRLS 252
OWR53707        183 S-TAAQQIEVFSRVLKSAIVGFLQSSDQWQNS---VTECAKMVCHGAHTYVYSQVIVHILSQEPRGGAI------MKRLN 252
EFA00603        181 S-TAAQQLEVFSRVLKTSIASFLTNPEDWQNT---SKECAKMVCHGQHTYVYSQVIIHVLARESKGGSS------MKRLS 250
XP_001944110    181 S-TASQQIEVYSRILKNFITESIKTSSENRQNt--IQECAKMVCHSQHTYVFTLVALQVLAKETNGGVN------MKRFS 251
EFX85644        187 S-TAAQQIEVFSRILKTSVGQYSESNDDDRQKh--IQECARMICHGQHTFVYSEVLLNVLSQEPKGGPS------IKRLS 257
Q922L6          193 S-TACQQLEVFSRVLRTSLATILDGGEENLEKn--LPEFAKMVCHGEHTYLFAQAMMSVLAQEEQGGSA------VRRVA 263 house mouse
EDV25448        188 S-TVCQHLELFTRQLQSCVHSVIAKGPTTSSAd--VDNMINMACHTEHGYLCCQFFLRILLYDIENSHL------IRFLM 258
jgi:OSTLU_93007 237 GpAAAAYFSIFHELLADHVKGIIEAGDDDERRmdfEERLKSMCCQSIGTYVFGQLMLATLGRDTDKATTkssqaiAARLS 316
XP_002431657    182 S-TAAQQIEVFSRVLKTAISGFLTNADDWQKN---IQECGKMVCHGQHTYVYSQVLLQVLSQETKGGSN------MKRLS 251
XP_310712       186 S-TAAQQIEVFSRVLKTAIAKFLSHPEDWQGA---IEEVAKMVCHGQHTYVYSQVLIQVLSQEAKGGFI------MKRLS 255 Anopheles ga...

Q29GI5          250 QEIIKYALQNNQNVTPITMA--LNGSAVYPQACQALTSMLTR----------------NTLNPADITVLFRNYSGSD--- 308 Drosophila p...
XP_011252244    253 QEITKCAQQNRHDVTPITMA--LNGAASSPGACQALASMLSR----------------NTLNPADITVLFRNFSTSE--- 311
OWR53707        253 QEITRCAQESGHDVTPITLA--LTPGESWRNARTALAAMLSR----------------GALNPADITVLFRAYTQPD--- 311
EFA00603        251 QEITKCAQKNGHDVTPITMA--LNGASAYPLACQALTSMLSK----------------NTLNPADITVLYRNYNAPD--- 309
XP_001944110    252 QEITRCAQERN-DVTPITMA--LNGAAPYDQPCAALSSMLSR----------------NALNPADINVLHKHYSSAD--- 309
EFX85644        258 QEITRHAIQSGHNVTAIIMG--LNGSAAHPRASQALSSMLSR----------------NALNPADITNLYKLYSATD--- 316
Q922L6          264 QEVQRFAQEKGHDASQITLA--LGTAASYPRACQALGAMLSR----------------GALNPADITVLFKMFTSMD--- 322 house mouse
EDV25448        259 QKIESGAISRGLAVSDIAMI--VNGVYQYTNVNAAVNNIFSR----------------NALDSTDVATLYEVYSGDE--- 317
jgi:OSTLU_93007 317 EEIEEAAASLHGAATVRRLApwLAASAADATAKYATADLLSSrpvgtntssvgqirdsGALAAGDLKKLLDLYVSSDvkk 396
XP_002431657    252 QEIIKCAQKNHHDVTPITMA--LNGATQYPQACQALTSMLSR----------------NNLNPADITVLFRNYSAPD--- 310
XP_310712       256 QEITKYALKNNHNVTPITMA--LNGSSRHPQACEALTSMLSR----------------NTLNPADITVLYRNYTSPE--- 314 Anopheles ga...

Q29GI5          309 PPPIDLIRNPQFLELLVDALFR--SGVKINPEHKPKYMFLLAYASAVIDQPAKKrp-lTERTLNKDELKSTIQAIEKAHA 385 Drosophila p...
XP_011252244    312 PPPIELLRNPQFLELLVDALFK--PGVKINPEHKSKYIYLLAYAASVCETTKKG----NTRKINKDELKTTIQAIEKVHN 385
OWR53707        312 PPPVHLLRIPHFLELLVDSLFK--SGSKLNPEHKPKYMHLLAYAASVCEGPAPG------RPI-KDELKATMQAIEKIHT 382
EFA00603        310 PPPIDLIRTPQFLELLIDALFK--PGVKLNPDHKPKYIHLLAYAASVYEMQAKKg---QKRVVNKDELQATIHSIETVHN 384
XP_001944110    310 SPPVSLLRIPQFLELLVQALFK--PGMKLNPEYKPKYIYLYAYSASVYEVTSGK----KRKIINKDDLKSTIQAVDKVHS 383
EFX85644        317 PPPVELIRLPQFMELLLDSLFK--PGVKLNPEHKSKYNYLLAYAASVAEVYKKN----QRKNTNRDELKATMQALEKAHQ 390
Q922L6          323 PPPVELIRVPAFLDLFMQSLFK--PGAKINQDHKHKYIHILAYAASVVETWKKN----KRVSIGKDELKSTSKAIETVHN 396 house mouse
EDV25448        318 PPPIEIIRHPRFLDLLIKRLFD--PDDKIDADLKSKLCFLLAYAVSVVETISET-----QTLLNTDDLKSTTNVIGRTLD 390
jgi:OSTLU_93007 397 KPSVAPLRHPDVLYNLISEAFKwtVDSGAN-RLRSECFELIALAAS-------------DDETSVDEVKA---ALTEAVA 459
XP_002431657    311 PPPIDLIRTPQFLELLVDSLFK--PGIKLNPEHKPKYIYLLAYAASVCDTPAKKig-sSRRQLNKEELKPTQQAIEKVHG 387
XP_310712       315 PPPIDLIRNPQFLELLVDSLFK--VGVKINQEHKSKYIYLLGYAASVCEIPTKKgqpkGHRVLNKDELKATIIAIEKVHA 392 Anopheles ga...

Q29GI5          386 I-CNVG-QGTSELIAELQTLYNCIKYPVVGVGVIRWIENVVMEPSFFK-LSTDSCP-THLAVLDEVAAVHPTLQQQILFL 461 Drosophila p...
XP_011252244    386 I-CNIN-KGSTELIAELHTLYQCIRFPVVSVGIIRWVECTVTEPSYFK-LCTEHCP-VHLALLDEVVVCHSLLHTKILNL 461
OWR53707        383 V-CSSS-ASSSELLAELPALYHCIRFPVVGMGVLVWVEGVVTEKSYFK-LCTEHCP-VHLALLDEVASCHPLLHHRLLKL 458
EFA00603        385 I-CNTN-KGSSELMAELATLYQCLRYPVVSVGIIRWVECTVTEASYFK-LSTEHTP-IHLALLDEVVTCHPLLHNQVLDL 460
XP_001944110    384 I-CNLN-KSSTELIAEVATIYHCIRYPAVAVGLICWVESTVTEPSFFK-LCTEHTP-THLALLDEVVTCHPQLHNIILKL 459
EFX85644        391 V-CTTA-KGSTELIAELGTLYQYIRFPVVSMGVFRWVEATVLEPSYFK-LSTEHTP-VHLALLDEVAAVNPLLHSNILDL 466
Q922L6          397 LcCNEN-KGASELVAELSTLYQCIRFPVVAMGVLKWVDWTVSEPRYFQ-LQTDHTP-VHLALLDEISTCHQLLHPQVLQL 473 house mouse
EDV25448        391 IiSHADcRSSNYLLSEIGNLYQYIRYPVVGRGLINWVDCIVSSSSFFN-YMGDSTAlIYLAILDEICTHHPLQHPTTFNL 469
jgi:OSTLU_93007 460 IvENAK-RGEMPEQTSVDKVFA---IPCATAGIIAAARSALTNEMYHRvVQVGNANsVFVHVLGEVAKKHIGLQGVVLEA 535
XP_002431657    388 I-CNTA-KGSGELIAELGSLYQCIKCPVVAVGIVRWVEFTVTEPSYFK-LSTEHTP-IHLALLDEVVTCHPLLHTKVLTL 463
XP_310712       393 I-CNVS-RGSSELIADISTLYSCIRFPVVGVGVIRWVENTVTEPSYFK-LCTESCP-LHLALLDEVACVHASLHDQILRL 468 Anopheles ga...

Q29GI5          462 LIRLFE----SKQDELEILVQLEMKKMILDRMVNLLTRGCVVPVLRYVKQCCAIEDTDVSLIRYFVTEVLETITHPYSPE 537 Drosophila p...
XP_011252244    462 LVHLFE----SKQDELEILVQLEMKKMLIDRMVNLLSRGCVVPVVYYIKQCWQRGDTDVSLIRYFVTEVLEAIAPPYTAE 537
OWR53707        459 LVQLFE----SPQDELEILVQLELRKMLLDRMVNLLSRGCVVPVLQYIKACWQRDDTDISLIRYFITEVLDAIAPPYTPE 534
EFA00603        461 LIRLFE----SKQDELEILVQLEMRKMVLDRMVNLLCAGCVVPVVKYIKQCWQKGDTDISLIRYFVTEVLETIGPPYSSE 536
XP_001944110    460 FVSLFE----SKQDELEILVHLEMKKMLLDRMVNLLCCGCVVPVIKYIEQCWHRGDTDISLIRYFVTEALEAVSPPYSVE 535
EFX85644        467 LVRLFE----SRQDELEILVQLEMRKMLLDRMVNLLTRGYVVPIVKYIKQCWQRGDTDISLIRYFVTEVLESIAPPYTSE 542
Q922L6          474 LVKLFE----TEHSQLDVMEQLELKKTLLDRMVHLLSRGYVLPVVSYIRKCLEKLDTDISLIRYFVTEVLDVIAPPYTSD 549 house mouse
EDV25448        470 LIKFLE----YEYNNGDIMLILRFKRHIIECMVHLVSRGYVVPVLNYIRKCLDTNSMDNSLIRNFVSGVLDIISPPYTPI 545
jgi:OSTLU_93007 536 LNAIIQscgsSHGAELAI--------SLLDLGCELVAAGHVMPTITAAANSWRR-TLDPSQIRYFANEVLEIAGPPYSRD 606
XP_002431657    464 LIELFE----SKQDELEILVQLEMRKMLLDRMVNLLSRGCVVPVVKYVKHCWTRGDTDISLIRYFVTEVLEAVAPPYTLE 539
XP_310712       469 LVRLFE----SKQDELEILVQLELKKMLLDRMVNLLARGCVVPVVKYISQCCTRGDTDISLIRYFVTEVLETVTHPYSSE 544 Anopheles ga...

Q29GI5          538 FVQLFLPMVENEEITGTMRGEGDNDPVSEFIVHCKAHY 575 Drosophila pseudoobscura
XP_011252244    538 FVQLFLPMVEDEEITGTMRGENENDLVSEFIVHCKTHC 575
OWR53707        535 FVQLVLPMVENEDITGTMRAEGEKDPVSEFRVHCKAHV 572
EFA00603        537 FVHLFMPMVENDEITGTMRGDGENDPVSEFIVYCKANY 574
XP_001944110    536 FVDLFLPIVENEEITGTMRCDGENDPVSEFIVHCKGmt 573
EFX85644        543 FVQLFLPMVENEEITGTMRGDGDGDLVSDFIVYCKANY 580
Q922L6          550 FVQLFLPILENDSIAGTIKAEGEHDPVTEFIAHCKSNF 587 house mouse
EDV25448        546 FIELFLPLLKSDVCISLRQSQNKDDPAVNFIDYCETyk 583
jgi:OSTLU_93007 607 FAVVMIRLLDSANSRKRM-----SKTVDDFVEDVRVNR 639
XP_002431657    540 FVQLFLPMVENEEITGSMRGDGENDPVSEFIVHCKAHY 577
XP_310712       545 FVQLFLPMVENEEITGSMRGEGDNDPVSEFIVHCKAHY 582 Anopheles gambiae str. PEST