Conserved Protein Domain Family
PRK05414

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PRK05414: PRK05414 
urocanate hydratase; Provisional
Statistics
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PSSM-Id: 235448
Aligned: 449 rows
Threshold Bit Score: 782.396
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
17547366   11 AADPRYDAAREIRAPRGTELHCKSWLTEAAYRMLQNNLDPDVAENPKHLVVYGGIGRAARDWACFDKILETLRELNDDES 90 
255531241  73 IYMYRFRPDYEMYARPVQEYPFQSLHAACIQLMIQNNLDPSIAQHPHELITYGGNGSVFQNWAQYLITMQYLAGMTDGQT 152
305665356  79 IYMYRFNPEYDIYARPIDAYPAKTPQASSIMLMIQNNLDPAVAQHPEELITYGGNGAVFQNWAQYLLTMKYLGTMTEEQT 158
146299668  73 IYMYRLRPDYRMYARPIDEYPGKSLQAKAIMHMIQNNLDYAVAQHPHELITYGGNGAVFQNWAQYLLTMQYLSEMTDEQT 152
255535561  81 IYMYRFRPDYEMKARDIAEYPGKSEQAKAIMLMIQNNLDYAVAQHPHELITYGGNGAVFQNWAQYLLTMKYLSEMTDEQT 160
260060752  82 IYMYRFRPEYRMVARPIDAYPAKIPEAAAIMLMIQNNLDPEVAQHPDELITYGGNGAVFQNWAQYLLTMQYLSEMTEAQT 161
119774769  77 IYMYRFKPEYAMKARAISEYPAKCEQAAAIMLMVDNNLDPAVAQHPEELITYGGNGAVFQNWAQYRLTMKYLSEMEADQT 156
150025999  73 IYMYRFRPDYEIKARPISDYPGKCDQAKAIMLMIQNNLDYAVAQHPHELITYGGNGAVFSNWAQYLLTMQYLSEMTDEQT 152
120434604  73 IYMYRFKPDYDFYARPIDEYPGESVQAKGIMLMIQNNLDPEVAQHPEELITYGGNGAVFQNWAQYLLTMQYLAMMDNEQT 152
295132663  73 IYMYRFKPDYKMYARAIDEYPGKSTQAKAIMLMIQNNLDHNVAQHSDELITYGGNGAVFQNWAQYLLTMQYLAIMEDDQT 152
17547366   91 LLVQSGKPVGVFKTHPDAPRVLIANSNLVPKWANWEHFNALDRKGLFMYGQMTAGSWIYIGSQGIVQGTYETFAEAGRQ- 169
255531241 153 LNIYSGHPQGLFPSSPAAPRVVVTNGMMIPNYSSADDLEKYNALGVTQYGQMTAGSYMYIGPQGIVHGTTITLMNAFRR- 231
305665356 159 LHIYSGHPMGLFPSSKEAPRVVVTNGMMIPNYSQPDDWEKYNALGVTQYGQMTAGSYMYIGPQGIVHGTTITAMNAFRK- 237
146299668 153 LTMYSGHPMGLFPSHKEAPRVVVTNGMVIPNYSKPDDWEKMNALGVSQYGQMTAGSYMYIGPQGIVHGTTITVLNGFRK- 231
255535561 161 LTMYSGHPMGLFPSHKDAPRVVVTNGMMIPNYSKPDDWEKFNALGVSQYGQMTAGSYMYIGPQGIVHGTTITVLNAFRki 240
260060752 162 LHMYSGHPMGLFPSSPDAPRVVVTNGMMIPNYSRPDDWERFNALGVTQYGQMTAGSYMYIGPQGIVHGTTITVLNAFRR- 240
119774769 157 LHLYSGHPMGLFPSSVDAPRVVVTNGMMIPNYSKPDDWERFNALGVTQYGQMTAGSFMYIGPQGIVHGTTITVMNGFRK- 235
150025999 153 LAMYSGHPMGLFPSHKEAPRVVVTNGMVIPNYSKPDDWEKMNALGVSQYGQMTAGSYMYIGPQGIVHGTTITVLNGFRKi 232
120434604 153 LAMYSGHPMGLFPSHANAPRVVVTNGMMIPNYSKPDDWEKFNALGVTQYGQMTAGSFMYIGPQGIVHGTTITVLNAGRKi 232
295132663 153 LAMYSGHPMGLFPSNENAPRVVVTNGMMIPNYSQPDDWEKFNALGVTQYGQMTAGSYMYIGPQGIVHGTTITVLNAGRKi 232
17547366  170 --HYsdrpsallkqglspegtapgsgrssaqvpG-S---HLAGRWILTAGLGGMGGAQPLAATLAGAVSLTIECQQSSID 243
255531241 232 --KL-------------------------------GmseSPAGRVFLTAGLGGMSGAQPKAGNITGCITVCAEINPEAAR 278
305665356 238 --VLk---------------------------qD-E---TPKGKIFLTSGLGGMSGAQPKAGNIAGCITICAEVNLVAAK 284
146299668 232 ---------------------------------IkQ---NPEGSLFVTSGLGGMSGAQPKAGNIAGCITVCAEVNPKITK 275
255535561 241 kkSP-----------------------------I--------GGLFVTSGLGGMSGAQPKAGNIAGCITVCAEVNPKITK 283
260060752 241 --VL-----------------------------PeAt--DFAGRVFLTAGLGGMSGAQPKAGNIAGCVTVCAEVNPAAAR 287
119774769 236 --VL-----------------------------EkGd--SPKGKIFLTAGLGGMSGAQPKAGNIAGCITVCAEVNPKAAT 282
150025999 233 -----------------------------------Kk--TTSGGLFVTSGLGGMSGAQPKAGNIAGCITVCAEVNAKITH 275
120434604 233 s------------------------------ksG-E---GLAGKLFVTSGLGGMSGAQPKAGNIAGCITICAEVNPKATQ 278
295132663 233 a------------------------------kkN-E---DLSGKLFVTSGLGGMSGAQPKAGNIAGCVTICAEVNEKAIK 278
17547366  244 FRLRTRYLDKQARDIDDALNLIRHhceRGEAVSIGLLGNAAELLPELVRRaragGLKPDLVTDQTSAHDLVN-GYLPAGW 322
255531241 279 KRHQQGWVDELIFNLDALLQRVKAakeIKETVSLAYIGNVVDVWEGFDAA----GVLVEIGSDQTSLHNPWSgGYYPAGL 354
305665356 285 KRHEQGWVDELITSIDELVSRTNRavqNNEVVSLAYVGNIVEVWERFDTE----NIFIHLGSDQTSLHNPWAgGYYPVGL 360
146299668 276 IRHEQGWINEVVTSTDELVARVALakaNKETVSIAYLGNVVDVWERFDQE----NIKIDLGSDQTSLHNPWAgGYYPVGI 351
255535561 284 IRHEQKWIDEIYDQLDELVERVKVakeKNETVSLAYLGNVVEVWEEFYEA----QLTIDIGSDQTSLHNPWAgGYYPAGL 359
260060752 288 KRHQQGWVDELLEDLDALAARTRQaiaGREVVSLAYLGNVVDVWERFADE----DIPVTLGSDQTSLHNPWAgGYYPAGM 363
119774769 283 KRHAQGWVDELIDNMDALVARVKQaqaNEEVVSIAFIGNVVNVWEAFDEH----DIFVHLGSDQTSLHNPWSgGYYPVDI 358
150025999 276 IRHSQGWVNEVFQNIDKLVARVILakaNKEVVSLAYLGNVVDVWERFDQE----NIHIDLGSDQTSLHNPWAgGYYPVGI 351
120434604 279 TRHKQGWVDEVIDNVEELAERVKKakaGKEVISIAYQGNVVEIWEYFAEN----DIYIDLGSDQTSLHNPWAgGYYPVDL 354
295132663 279 TRHSQAWVDEVITDIRLLAERVSKakkDKEVVSIAYHGNIVEIWEYFAEN----DIYIDLGSDQTSLHNPWAgGYYPVTL 354
17547366  323 TVEQWRAAQRDPAQhaHLSAEAARSCAVHVQAMLDFQSMGIPTVDYGNNIRQVAFDQ--------GVK----------NA 384
255531241 355 TYAEANQMMAEAPA--LFKEKVEASLIRHAAAVNRHVNKGTYFFDYGNAFLLECSRAgadvmaddGVD------------ 420
305665356 361 DFEESNDLMGNDPK--AFKEKVQESLRRQVNSINKHTAKGTYFFDYGNAFLLESSRA--------GADvma----knnID 426
146299668 352 SFEEANDLMANNPE--LFKEKVQETLRRHADAINKHTAKGTYFFDYGNAFLLEASRA--------GADvma----ennID 417
255535561 360 TFEESNKMMAENPE--LFKEKVQESLRRHAAAINKHTEKGTYFFDYGNAFLLEASRA--------GADvlsenptigrE- 428
260060752 364 SFEAANRMMAEEPE--KFREKVRESLRRHVTAINRHTQKGTYFFDYGNAFLLEAYRA--------GADiqg----adgKE 429
119774769 359 SYDESNRLIREEPE--LFKTKVQATLKRHADAINRHTAKGTYFFDYGNAFLLEASRAggdvmaenGID------------ 424
150025999 352 SFEEANEMMANNPK--LFKEKIQETLRRHTKAINKHTAKGTYFFDYGNAFLLEASRA--------GADimae----nhiD 417
120434604 355 GFEEANELMASNPE--KFKEKVQESLRRQTTAINKHTKRGTYFFDYGNAFLLEASRA--------EADimse----dgkD 420
295132663 355 SFEEAKEMMANNPE--QFKTEVQESLRRQTTAINKHTAKGTYFFDYGNAFLLEASRA--------GADila-----knGD 419
17547366  385 FDFPGFVPAYIRP-LFCEGRGPFRWVALSGDPEDIYKTDAKIKELFP------------HNAHVHRWLDMARERIAFQGL 451
255531241 421 FKYTSYVEDILGPmCFDYGFGPFRWVCTSGDPEDLVTTDVIAMEVLQeirteapveiqqQLQDNITWIREAGANKLVVGS 500
305665356 427 FKYPSYVQDILGPmCFDYGFGPFRWVCTSGKSEDLQKTDAIALEVMKeikkeapeeiqqQMQDNITWIQEAEQNKLVVGS 506
146299668 418 FKYPSYVQDIMGPmCFDYGFGPFRWVCTSGKPEDLLKTDAIACEVLEkmaetapneiqqQMQDNIKWIKGAQENKLVVGS 497
255535561 429 FRYPSYVQDIMGPmCFDYGFGPFRWVCTSGKPEDLQKTDEIACQVLEemiknspeeiqqQMKDNITWIKGAQENNLVVGS 508
260060752 430 FRYPSYVQDILGPlCFDFGFGPFRWVCTSGNPEDLRITDQIAREVMEaqlqdapesirgQLRDNIRWISRAEENALVVGS 509
119774769 425 FKYPSYVQDILGPmCFDYGFGPFRWVCTSGNSADLDRTDAIAAEVLArimaeapaeiqqQMQDNITWIKDAKQNKLVVGS 504
150025999 418 FRYPSYVQDIMGPmCFDYGFGPFRWVCASGKPEDLAKTDAIACQVLEqmmqnspqeikqQMQDNITWIKGAQQNKLVVGS 497
120434604 421 FRYPSYVQDIMGPmCFDYGFGPFRWVCASGKEEDLQKTDKIATEVLNklkenspaeiqqQMQDNIQWIKGARENKLVVGS 500
295132663 420 FRYPSYVQDIMGPmCFDYGFGPFRWVCASGKEEDLAKTDKIATEVLErlkqespaeiqqQLEDNIRWIKGAQQNKLVVGS 499
17547366  452 PARICWLGLGERHAAGLAFNEMVRKGELKAPIVIGRDHLDTGSVASPNRETEAMRDGTDAVSDWPLLNALLNTAGGATWV 531
255531241 501 QARILYADAEGRAKIAAAFNTAVQEGRLKAPIVLGRDHHDVSGTDSPFRETSNIYDGSRFTADMAIQNVIGDSFRGATWV 580
305665356 507 QARILYADAEGRSKIAEAFNQAVKKGGITAPVVLGRDHHDVSGTDSPFRETSNIYDGSKFTADMAIHNVIGDSFRGATWV 586
146299668 498 QARILYADAEGRIKIAEAFNQAIAKGEI-GAVVLGRDHHDVSGTDSPYRETSNIYDGSRFTADMAIHNVIGDSFRGATWV 576
255535561 509 QARILYADAEGRMKIAEAFNKAIANGEI-GAVVLGRDHHDVSGTDSPYRETSNIYDGSRFTADMAIQNVIGDSFRGATWV 587
260060752 510 QARILYADAEGRIAIARAFNEAIADGRLQAPVVLGRDHHDVSGTDSPFRETSNIYDGSRFTADMAIHNVIGDSFRGATWV 589
119774769 505 QARILYADAEGRMEIAKAFNDAISRGEI-GPVVLGRDHHDVSGTDSPFRETSNIYDGSRFTADMAIHNVIGDSFRGATWV 583
150025999 498 QARILYADAEGRIKIAEAFNQAIAKGEIQT-IILGRDHHDVSGTDSPYRETSNIYDGSRFTADMAIQNVIGDSFRGATWV 576
120434604 501 KARILYADAEGRIAIAKAFNDAISRGEI-GQIVLGRDHHDVSGTDSPYRETSNIYDGSSFTADMAIQNVIGDSFRGATWV 579
295132663 500 KARILYADAIGRIEIAKAFNKAIENNDI-GPVILGRDHHDVSGTDSPYRETSNIYDGSRFTADMAIQNVIGDSFRGATWV 578
17547366  532 SLHHGGGVGMGYSQHAGVVIVADGTDAAARRLARVLVNDAGSGVMRHA-----DAGYETAVACAKR--------NG---- 594
255531241 581 SVHNGGGVGWGEVINGGFGMVLDGTATAAEKLKSMLFFDVNNGIARRSwarnkEARFAIEREMGRTp------dLN---- 650
305665356 587 SIHNGGGVGWGEVINGGFGMVLDGSAEASKRLKNMLFYDVNNGISRRS-----WARNNESIFAIKRemer-tpeLS---- 656
146299668 577 SIHNGGGVGWGEVINGGFGMVLDGSTEASKRLASMLFWDVNNGISRRS-----WARNDGAVFAIKRa-------MEvepl 644
255535561 588 SIHNGGGVGWGEVINGGFGMLLDGSADADRRLKSMLFWDVNNGISRRS-----WARNEGAVFAIKRamea-epnLK---- 657
260060752 590 SIHNGGGVGWGEVVNGGFGLVLDGTPAAEKRLANMLFFDVNNGIARRS-----WARNPEAM-QALNreigrspgLS---- 659
119774769 584 SIHNGGGVGWGEVINGGFGMLLDGTEAAERRLKSMLLFDVNNGIARRSwarneEANFAIKREMART--------PK---- 651
150025999 577 SIHNGGGVGWGEVINGGFGMVLDGSKEASKRLESMLFWDVNNGISRRS-----WARNNNAIFAIQRamaa-qplLK---- 646
120434604 580 SIHNGGGVGWGEVVNGGFGMILEGDKSSEDRLKSMLFWDVNNGIARRS-----WARNEEAIFAAKRamnm-npqLK---- 649
295132663 579 SIHNGGGVGWGEVINGGFGMILEGNKQSEKRLESMLFWDVNNGIARRS-----WARNKGAV-FAANramqiepkLK---- 648
17547366  595 --LKLPMIG 601
255531241 651 --ITLPNLV 657
305665356 657 --VTLPNIV 663
146299668 645 lkVTLPNLV 653
255535561 658 --VTLPNFV 664
260060752 660 --VRLPQLV 666
119774769 652 --LKVTLAN 658
150025999 647 --ITIPNIV 653
120434604 650 --VTIPNLV 656
295132663 649 --VTLPNMV 655
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