4GRH,3RV8


Conserved Protein Domain Family
TrpE

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COG0147: TrpE 
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, Coenzyme transport and metabolism]
Anthranilate/para-aminobenzoate synthases component I is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Statistics
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PSSM-Id: 439917
Aligned: 691 rows
Threshold Bit Score: 293.932
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4GRH_A         5 THA-PLIH------PLph-----piDLLALQQH------D----P---A--RFPLLMESTAsG-TAQGRW-S-LL----- 49  
WP_010894380   3 kIL-TTTT------DVpldgsdlreNAFLIYRKl-----L----Kn-fDs-DQLMLLESLGiN-SVDSRV-S-MVginpi 61  
WP_102993915   1 -------Mye--etFVag-----akEPLKVLHHla---tSefvtDy--------LLYEGN-------G---EvRIvgnvv 45  
WP_087457529   3 rKI-GVHTrqksypRIc--------ESFEVFQAl---------tEtygA--ENAFLLDSVK-DvH--SRYcQsSIalfpv 59  
AFZ25954       6 S---GFLTyy--elFIpe-----pmEPLILLQNll---sSgrfsNy--------VMYESK-------N---SiRIagnvl 54  
WP_014140115   3 eLL-DVT--------VtaisvettaRALEVRAEl-----C----Ri-lGp-EEVFLLDDLHpD-RSHAGTgT-VVgfgrl 60  
WP_015583977   1 -------Mki--seFLhl-----alPEEQWLPTisgvlrQfg-dE---Ec----YVYERQ-------PCW---YLgkgcl 48  
WP_052097894 527 qqasG--Apg--ecTLpl-----aaPPLDVVCHll--------aD---EktSh-IAYEQQ-------GRW---RVgigsa 575 
WP_011810181 527 aPApAIARya--erRMav-----atAPLALAARla---rNls-sQ---Hy----TLYEHG-------SEW---SIgldsv 578 
WP_015128993   6 K---TEIKyq--eaFVpg-----krDAIAVLQNlv---qAgiftSy--------MMYECK-------D---GiRIagnel 54  
4GRH_A        50 --LVAQGDGLRLDadgQv------RdqhdlvQPg--T--FLQ-----ALDRAWQhERLSHDGShSl--------PFRGgw 104 
WP_010894380  62 itVNVKNKTISIH---Snpi--llKe----lNIa--D--SIA-----SLQTTTLsLSVyQ--LvDkkmvwqflkEFEKnf 121 
WP_102993915  46 akIEVLQDIVRFQyag------------dttEEpakD--PLK-----QAERFLH--Tl----------------PLEQwt 88  
WP_087457529  60 lnVRVKGRRFALDg--QpalteviGan--lvQDg-tDltHFAgkvskLLDGVIHsFELHDRQTmS---------KYSFgf 125 
AFZ25954      55 aeVSVSTETVSLSykg-----qtiC------TEaisD--PLK-----QVESALA--Sl----------------PVKNwt 98  
WP_014140115  61 aeISVTGDRVTVRg--SgpvadllRarc-grTTt--D--PWA-----MLRRVTAlFRVhT--DvRg---------FSFgf 117 
WP_015583977  49 arLHINADGTQATfid-----dagE------QKwavDs-IVD-----CARRFMA--Hp------Q----------VQGrr 93  
WP_052097894 576 aeVRAYADRTELAlpg-----qppL-------TwrgAr-WRE-----NLQQALD--Al----------------PFSDwq 619 
WP_011810181 579 ldVTIDADGTVRRsn---------------gaAwka-lpPCA-----GVAQALA--Gi----------------PFEGwr 619 
WP_015128993  55 ahVAVSKDSVSLNglg------------ksySEpvsH--PLK-----QVERLLG--Tl----------------PINNwt 97  
4GRH_A       105 ------------aLMLDYEVASQIEPVLPARARGDGRPTALALRCPAAVLHDHHNEAsfviaeageqalldalva----- 167 
WP_010894380 122 sqvpthqcgimafSCFSYETIHYIETIPETELNDQDDHDITLILYQSQLV--IEQNKaelitysfpgvedfyvaniidai 199 
WP_102993915  89 -----------ayGYVGFDICKYYYNY----FKSSAEPILCMIVPEFELRFTQSGvyiksvtqqaeliqi---------- 143 
WP_087457529 126 ------------vGHLSYDAIRYFENIPQTTVDDRAIDDIRLQVHQVVLQFERDAIHvhineieglptpsfaeieaf--l 191 
AFZ25954      99 -----------ayGYVGFDISRFYYPY----SKAIQQPLLYFMVPETEIHITPKGvyvksirlptkitev---------- 153 
WP_014140115 118 ------------lTTVGYDAAAYMEELPPRQV-EPDVPDLTLTLFQDTLWFGRQDGPpvllrasgpglpeplplgll--r 182 
WP_015583977  94 -----------vyGQVGFNFAAHARGIAF---DAGEWPLLTLTVPREELVFEKGNvtvytdsaegcrrlcew-------- 151 
WP_052097894 620 -----------afGCGHFELSALTYHLPF--APTAG-PLLTLFIPRWQLTLTADGaalkahdaaelpllearlrea--dr 683 
WP_011810181 620 -----------ayGRADFELAHLIHGLGG---TSGTRPLLKLSIPRSEIRLRSGEaliraldpadlaametlv------- 678 
WP_015128993  98 -----------ayGYVAFDIARFYSSY----SKAIEQPLLYFLIPETELRLTEDGihikttqslaqiehk---------- 152 
4GRH_A       168 lasaalpeagqgwqppqaVGED-APQRFTDGVRRVIEYLRAGDVFQVNLSRRWNAQFaaPvSPQALYAQLRRANPAPFAG 246 
WP_010894380 200 tcmtdveqvqdknidfevIQET-TRHDYLDKVRKALHHVTVGDIYQVQIGQKIQVKA--EtTPLDVYRRLRILNPSPYMY 276 
WP_102993915 144 ---leseidlptyeryplKLDYaDRETYQQKVQCLIDNIQQRQLHKTILSRSVKVHD--QlDPILTYAEGTNVNNSVRSY 218 
WP_087457529 192 reyaepefagydptllrvEEDV-KEADFLKRVERCKAYIEAGDIFQVVISKRNRVIG--QiDSMQVYYRLKQINPSPYMY 268 
AFZ25954     154 ---lfgdsqlkdyiatpiVLDFaDKQHYQNQVDTMISAIQSGQLHKAIISRHLKVKG--NmDVLGTYVLGAKNNNSARSY 228 
WP_014140115 183 gipdadlpvpdapaplevRDTV-DRETFLGWVERCLDRIRVGDIYQIQVGHRIDVRS--AlTPEEVYRRLSARNPSPYMY 259 
WP_015583977 152 --vkeastttrgdsmavdtA-L-NGEVYKQQVARAVAEISRGEYVKVIISRAIPLPS--RiDMPATLLYGRQANTPTRSF 225 
WP_052097894 684 paaaigedeawreriaqriRQQ-DADGYRQRVAAAVAEIARGEYQKVILSRRIEVDD--NiDLLASFRLGRQHNTPARAF 760 
WP_011810181 679 aaqdassgpeigqpveiaRDSG-TEHAYKQRVAAAVGEMQAHAYQKVILSRTAEAPA--AlDMVSSYLVGRRFNTPARSF 755 
WP_015128993 153 ---lsidvqlpdyvstsiKLDFaDRDSYQNRINTLIKAIQKGELHKAIISRSVKLAG--NlDILGTYVVSARVNNAARSY 227 
4GRH_A       247 LFSAHGRHVVSSSPERLVSVH-AGHAQTRPIAGTRP-RFEGDD-DAARIQELVGHPKERAEHVMLIDLERNDLGRICLPG 323 
WP_010894380 277 LFSINGQTVIGASPELFLRIStDEEILMRPIAGTLG-KR-EGRtLHHATQHLQADNKEVAEHMMLVDLCRNDIYRVCTPE 354 
WP_102993915 219 CLKLGGAKVVGFSPEILMAVDrERFVLTNPLAGTRP-RGDTPErDRQLHDELFTDAKEVKEHALSIWLAQDEIRSVCEPD 297 
WP_087457529 269 YVDYGDYKIYGTSPELQIRLE-DGVAQMRPIAGTSKgKGKRPEeNVQLIERLRNDEKERAEHLMLIDLCRNDLGRFCEPG 347 
AFZ25954     229 CLGLGDVSAVGFSPEIFMKSTaGGFVVTNPLAGTRP-RGSSSEeDASLQGELFSDAKEVKEHALSIWLAQSEMASVCLPQ 307 
WP_014140115 260 LLTQSGTTLVGASPELLFRLD-DGLITMRPIAGTTR-RDPTGAdNARRVAELRADVKERAEHVMLVDLSRNDVGRVCRPG 337 
WP_015583977 226 MFRQQGREALGFSPELVMSVTgN-KVVTEPLAGTRD-RMGSPEqNKAKETELLHDSKEVLEHILSVKEALAELAVVCRPG 303 
WP_052097894 761 AVRLGEEQFVGFSPETVVEVSaGGAVSTQPLAGTRA-LTADEAeNRRLREVLTGDTKEIAEHAVSVKLAFEELAPLCEEG 839 
WP_011810181 756 LLRDGDFEAYGFSPETVVEIDaSGRVSTQPLAGTRA-LSGDTAkDERLRRELLADAKEIAEHAVSVKLTLQEMAEVCAPD 834 
WP_015128993 228 CLKIGDVSAVGFSPEILMQVSeDGFVITNPLAATRP-RGENLAeDIRLSGELFTDAKEVKEHSLSIWLAQNEITSLCLPE 306 
4GRH_A       324 TVVVDELMTVESYAHVHHIVSNVSGHLRPEVTPGEVIAATFPGGTITGCPKVRCMQIISELEQVPRGAYTGAFGWLNR-D 402 
WP_010894380 355 SLKVSGVLEIEEYSHVYHMVSTTKAMLKQGLDKYDVMIASFPAGTMTGAPKVRAMEIISELEDSQRGKYAGALGILGIgS 434 
WP_102993915 298 TVRVLDFMQVKRYRCVQHLSSRVGGTIKADRTSWDALKALFPGITVSGIDKASALEWISQLEEEPRGIYAGAVGWIDS-S 376 
WP_087457529 348 SIYVKDFMVVEEYSHVYHMVSTVEGQVDSSRNVFDMFLATFPAGTLTGTPKVRAMEVIDELEEFDRGAYGGVIGFIDF-L 426 
AFZ25954     308 TVQILDFMEVKKYRTVQHLSSQVGGQLKQGLTSWDAMKALFPGITVSGIDKHRALEWIDRLEDEPRGLYAGAIGYINS-E 386 
WP_014140115 338 TLAVTDLMKVEEFSHVFHLVSTVTGTLDAGRDVWDVLCATFPAGTMTGAPKLRAMEIIDEIEIERRGLYAGAVGLVDV-R 416 
WP_015583977 304 SVVVEDLMSVRKRGSVQHLGSGVSGQLAENKDAWDAFTVLFPSITASGIPKNAALNAIMRIEKTPRELYSGAILLLE--D 381 
WP_052097894 840 STRVSDFMSVSLRGSVQHLASRVEGQLRAGCSGWDAFAALFPAVTASGIPKAPAIAAIRRLEPTPRGAYSGSVFWLSS-K 918 
WP_011810181 835 SLRVSEFMDVYRRGSVQHLASRVAGQLAPGRDAWRAFEKLFPAVTASGIPKREALDSIRRHEPGPRGLYSGCVMLVDS-N 913 
WP_015128993 307 SIKVFDFMEVKKYRCVQHLSSRVGGQLKPEHTLWDALKVLFPGITVSGIEKDKALNWIDILEEEPRGIYAGGIGWIDS-H 385 
4GRH_A       403 GDLDLNILIRTAEV-----DGHEVSFRTGAGIVVDSDPDKELDETRAKARGLLRALGQ 455 
WP_010894380 435 NYINTALCIRSTVL-----KNQVYTLRASAGIVSDSQEQSEYLETLHKMGSIFKAITG 487 
WP_102993915 377 DRADLAIAIRSVFQ-----YGDVISFQAGAGIMGESNPENEYLETVNKMNTMLSTLVL 429 
WP_087457529 427 GNMNTAIVIRTIIQ-----RDDVAYFQAGAGIVADSDPEQEWAECDHKLRALTATLLK 479 
AFZ25954     387 GASDLAIAIRSAYQ-----YGDSVYLNAGAGIVAESLPEREYIESVNKMNTMLTNLVM 439 
WP_014140115 417 GWAEFALCIRTVTHrepspGDHRYATQSCAGVVALSEPKREWDETLAKMGAAHWALTG 474 
WP_015583977 382 ARFDAALVLRSVFQ-----DSQRCWIQAGAGIIAQSTPERELTETREKLASIAPYLMV 434 
WP_052097894 919 GELDAALVLRSLYR-----RDGGYSLQAGAGIIDQSQPARELEETIEKLESVSRFLVR 971 
WP_011810181 914 GAMDAALVLRSAFR-----SGDRCWLQAGAGLVPSSTPDREWTETCEKLESVSRHLRL 966 
WP_015128993 386 GAADLAIAIRSVYQ-----YGDSIHLNAGAGIVAESVPENEYIESVNKMNTMLTNLVL 438 
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