1JR3_D 4 LYPEQLRAQLNEG-LRAAYLLLGNDPLLLQESQDAVRQVAA-AQGFEEHHTFSIDPNTDWNAIFSLCQAMSLFASR---- 77 Escherichia coli 15894555 2 INYTELEENIKKNnIENVYIMCGFNEKLMKESINKILKKSIsQDFESLNYSVFDGNEVEFEDILNACETVPFMSEKrmvv 81 Clostridium acetobu... 15791990 1 MYRKELQILLSKDsIPNFFFLYGADNFQSELYAEFIKEKYK----PDETLKL-FFEEYNFTRASDFLSAGSLFSEK---- 71 Campylobacter jejuni 7674418 1 -MYRKDLDHYLKQrLPKAVFLYGEFDFFIHYYIQTISALFK-CDNPDIETSLFYASDYEKSQIATLLEQDSLFGGSs--- 75 Helicobacter pylori 2496380 1 -----------------MTIIYGQDIGLIHQKLSQIKSNSP----YKTIW--FKDLKQLYDLFS-----QPLFGSN---- 48 Mycoplasma genitalium 2496381 1 --MGCGACCILWVqSFTMTVVYGADIGLIHQQLNQLLNPAA----CKQVW--FQDVNKLYDVVLN----QNLFAED---- 64 Mycoplasma pneumoniae 15828933 1 -----------------MHLIYGQEEFLIESKTKNIIENQK----KDSIVFT-FYENFEIDDLLNDIVQKDLFSPN---- 54 Mycoplasma pulmonis 15642955 1 ---------------MPVTFLTGTAETQKEELIKKLLKDGN----VEYIRIH-PEDPDKIDFIRSLLRTKTIFSNK---- 56 Thermotoga maritima 15639576 1 ---------------MSVWLFTGPEIGERDSAVQEVCARAQ--AQGTVDVHRLYAHETPVADLVDLLRTRALFADA---- 59 Treponema pallidum 13357888 1 -------MNLIN---KELFLITGDNRLKMDQKINEIATSFD-----ELVKIN--DQEISLISFKNLIEQDDLFNSN---- 59 Ureaplasma urealyticum
1JR3_D 78 --QTLLLLLPENGPNAAINEQLLTLTGLLH----DDLLLIVRGNKLSKAQENAAWFTALANrSVQVTCQTPEQA-QLPRW 150 Escherichia coli 15894555 82 vyRAGFLNDNSSGSNKNSDKLIKDIEKYVPnvpkHCILVMYYVFDNTREKPSYRVKKFDKK-VCVVEFSKLRGM-QFQKK 159 Clostridium acetobu... 15791990 72 --KLLEIKTSKKIP--TKDLKVLVELCKNN----TDNFFLLELYDESSKQSDIEKIFSPHF----VRFFKANGAkEGVEL 139 Campylobacter jejuni 7674418 76 -lVVLKLDFALHKKFKENDINLFLKALERPs--hNRLIIGLYNAKSDTTKYKYTSDAIVKF----FQKSPLKDE-AICAR 147 Helicobacter pylori 2496380 49 ---NEKFIVNNCSFLEKTSLTRQENLCLEKlk-tTDVVLTVYT---DNPFSGIKTIKSITT----VFCDKLDWK-SMHKA 116 Mycoplasma genitalium 2496381 65 ---TKPILIHNCSFLEKNNLTKAELHCLKTlk-dTDVVVTIYS---DSPANALINDRAITK----YACKPVTAK-TIHQV 132 Mycoplasma pneumoniae 15828933 55 --KIIHIKNWKLLENPRPSKVILNKLKLLSeiieNDKSLIFIFSHIGEIEKNFLSDFLLKK-ASVKHYKKLELN-EKIKF 130 Mycoplasma pulmonis 15642955 57 --TIIDIVNFDEWK-AQEQKRLVELLKNVP----EDVHIFIRSQK-TGGKGV--ALELP---------KPWETD-KWLEW 116 Thermotoga maritima 15639576 60 --VCVVLYNAEVIKKCDEVHVLTEWIKDGGs--rADVFLVLISDSVSIHKRIEQNISPVHK----RVFWELFEN-KKHAW 130 Treponema pallidum 13357888 60 --KIYLFKNVNWFEnLEHLKNVSDLIDYFFnn-hVAIIITIESTKISTAKKIQETIAKFNH---QITFMTYTNE-NAMAF 132 Ureaplasma urealyticum
1JR3_D 151 VAARAKQLNLELDDAANQVLCYCYE----GNLLALAQALERLSLLWPDG-KLTLPRVEQAVNDAAHFTP--FHWVDALLM 223 Escherichia coli 15894555 160 VKDVFAEKGKQIGKTELNYFCSRVE----NNMDIVYNEIEKLCCYTLEK-EITKESIDNLLQPNETDDI--FNLVDYISQ 232 Clostridium acetobu... 15791990 140 LSIKAKQLGVEITQNALFTLFTSFD----ENLYLAASELNKFSGLRVDEkTIEQYCYSLNTGSFESFFD------KILKK 209 Campylobacter jejuni 7674418 148 FFIPKTWESLKFLQERANFLHLDISghllNALFEINNEDLGVSFNDLDKlAVLNAPITLEDIQELSSNAgdMDLQKLILG 227 Helicobacter pylori 2496380 117 IGEVCRELNLKLDLEIIDWLANALP----LNMGVIYQEINKLSLLGKNE-IKDNKLVETVICDYQPVQI--YKLTKALTN 189 Mycoplasma genitalium 2496381 133 ISKAAKTLKLNLNPDLIDHLATILP----FNLGVIEQELRKLTLLSPAE-LQDKKMLEAVLCDYQTSQI--LQLTDAMVR 205 Mycoplasma pneumoniae 15828933 131 IESYVTKNKIKISTVLISYLLINVS----SSISIVINEINKLFLENQN---ITREMIEKSVGFYTKEPN--FEFINSIKS 201 Mycoplasma pulmonis 15642955 117 IEKRFRENGLLIDKDALQLFFSKVG----TNDLIIEREIEKLKAYSEDR-KITVEDVEEVVFTYQTPGY--DDFCFAVSE 189 Thermotoga maritima 15639576 131 VQRFFFQHEMRIEQEAIESLLELVE----NNTRALKTVCTQLSLFFEKGrRITAHDISSLLVHTKEETS--FTLFDALSK 204 Treponema pallidum 13357888 133 LKEELNQRNLSLNKSIMQTIIQKTN----FNINFLNNELDKIELINDFLkNHGMFDINNFICDYGEYQI--FSLLNLLYQ 206 Ureaplasma urealyticum
1JR3_D 224 GKSKRALHILQQLRL-EGSEPVILLRTLQRELL-LLVNLKRQSAHTP-----LRALFDKHR--VWQNRRGM--------- 285 Escherichia coli 15894555 233 SKPEMAITVLNEIMY-KGVKANSILYMVERQFK-LMLSIKIGIENKQs----KEALVKELKl-NPYVCDKM--------- 296 Clostridium acetobu... 15791990 210 QDFKSELEKILDNFN-----EIALINSLYNSFYrLFKIALYAKINGKi----DFKELLGYT--PPPQVGQN--------- 269 Campylobacter jejuni 7674418 228 LFLKKSALDIYDYLLkEGKKDADILRGLERYFYqLFLFFAHIKTTGLm----DAKEVLGYa--PPKEIAEN--------- 292 Helicobacter pylori 2496380 190 SQIVKAFKYIDELAS----T-KPNFATQFLEFF-SGELLLALMVKSCn----PKQLTNINlnvNQFRLIAI--------- 250 Mycoplasma genitalium 2496381 206 LQTAKALKLIERLFL----P-KQLTPPQFLEFL-ANELLLALMVKGVk----PQAVFQLQwnvNPFRLKAI--------- 266 Mycoplasma pneumoniae 15828933 202 RNSNSIWKTFLEQKN-SGIEPLDLLKQISSAFI-LGNKINNIIKLDHs----LDQVAKILNv-HIYRAKEI--------- 265 Mycoplasma pulmonis 15642955 190 GKRKLAHSLLSQLWK--TTESVVIATVLANHFLdLFKILVLVTKKRYytwpdVSRVSKELGipVPRVARFLgfsfktwkf 267 Thermotoga maritima 15639576 205 RDLEHSLMILNTLLCsKDVAPVQILAGLLTRSV--ALRIGTIYRR-------TKRTLQR--------------------- 254 Treponema pallidum 13357888 207 HKINESINLINKMLI-DKIDELTIINMLATIMS-THYLIKLLHEKKYn----KNVISSSLNq-KPYIIDLN--------- 270 Ureaplasma urealyticum
1JR3_D 286 -MGEALNRLSQTQLRQAVQLLTRTELTLKQDYG----QSVWAELEGLSLLLCHKP 335 Escherichia coli 15894555 297 -INECKR-FTMKKILKSLDICLRTEKELKSVSG----DPKFKMEVLIINLAII-- 343 Clostridium acetobutylicum 15791990 270 -LSSQAFSLKIEQYKEIFTLLLKSEYELKTNPKlvkkEFLISNLLKLARILKN-- 321 Campylobacter jejuni 7674418 293 -YAKNALRLKEAGYKRVFEIFRLWHIQSMQGQK----ELGFLYLTSIQKIINP-- 340 Helicobacter pylori 2496380 251 -QSQYHN-FTSKVLVNIINAIQKLDIKLKHNDG----FAIPLLKNFALSFFTN-- 297 Mycoplasma genitalium 2496381 267 -QSQYRF-WSTNQLTALINAIWQLDIKIKRNDG----LAIHLLKHFVLRFFAQK- 314 Mycoplasma pneumoniae 15828933 266 -FSLIKG-FSQNSINEIIELLELTDKRIKTTYM----DPEMALDFFILKLIRHYN 314 Mycoplasma pulmonis 15642955 268 kVMNHLLYYDVKKVRKILRDLYDLDRAVKSEE-----DPKPFFHEFIEEVALDVY 317 Thermotoga maritima 15639576 ------------------------------------------------------- Treponema pallidum 13357888 271 -LKLIRN-YSAKFLLKKMYDLLQLEIKVKENKI----DKYFGLINWVLNF----- 314 Ureaplasma urealyticum
Jiyao W et al.(2023). "The conserved domain database in 2023.",