Conserved Protein Domain Family
GT4_GT28_WabH-like
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cd03811: GT4_GT28_WabH-like 
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH
This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.
Links
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Statistics
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PSSM-Id: 340839
Aligned: 63 rows
Threshold Bit Score: 147.12
Created: 15-Dec-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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putative
Feature 1:putative ADP-binding pocket [chemical binding site]
Evidence:
  • Comment:Some of the residues involved in ADP binding bind indirectly.
  • Comment:Based on similarity to sequences with known structure
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                     #                                                                  
AAX20105       2 RILFVIDGlp-gGGAEKVVLTLAAQf------------lRDGDRVSLISLRDvceyplpegldyqvva---------drc 59  Klebsiella pneu...
CAE06692       3 RVAVHLHQls-lGGAERITVMWCQWl------------vAMGHHVQLFLGQSdkseffapp------------------- 50  Synechococcus s...
CAD74550       4 KIACVIHSld-gGGAERVMAGLASRl------------aDREHSVTLITLDDgkhdrhevdprvsr-------------l 57  Rhodopirellula ...
NP_800918      5 KILHIINDlsqnGGAQKFLVDLVLEh-------------NPEYEIKILVLCAendyleqls------------------- 52  Vibrio parahaem...
NP_864687     75 RVLLMASSmr-gGGSELQTAMLARHl------------dRGRFDVHLYLTQAvgdllstipndvtihh--------ppes 133 Rhodopirellula ...
NP_869516      2 NIDLIITEmn-fGGAERALTQLAIGl------------rDRGDDVRLFSFGKlptadslpkgndrlvqq------lhdeg 62  Rhodopirellula ...
NP_797846      6 RILYVHYGdnwiRGSEVVLLDLILGi------------dRDKFEPIVWSNCQpliekcqdlgikaehst-------fnlv 66  Vibrio parahaem...
NP_953025      2 KVLHVIDSgg-lYGAEVMLLNLAAEq------------aAMGLEPVIASIGDplcgekplekeavr-------------r 55  Geobacter sulfu...
YP_003610664  10 KILLLDTGke-wGGGTNSMLELLKRi------------dRDKFDITCCFYNDysraggqtigqvlnsigiplivipqhkq 76  Enterobacter cl...
Q04975       163 RLALCTGSlg-sGGAERQISRLAIEiarkyrqkgkigglKVEEPVELIIRSLtpelrqdfflkevleeqvev-leiakit 240 Salmonella ente...

Feature 1                                                                                        
AAX20105      60 rkpwrkltelsrRARQLDAAVVRAEQqg------------qFDLVLSNlhkt----------driVARSRALRe------ 111 Klebsiella pneu...
CAE06692      51 ---asvkiirrpAGLLSVIWLRRLLLqn------------pPDLCIGItt--------------rPAVNLLLAsvg---- 97  Synechococcus s...
CAD74550      58 sidvlstpgntvSLWSRTLRLRSTIAsg------------nFDVVLSFcd--------------aTNWLTLLAtrg---- 107 Rhodopirellula ...
NP_800918     53 ----argiqcfnWQTLSLSEKWSLLRw--------------PDLVHGHly--------------pSIYLALLAig----- 95  Vibrio parahaem...
NP_864687    134 fsprisdripggLLKRQAEWFRDLIRra------------dVDVIYDRtfh------------mtLIAGHPIVqrgss-- 187 Rhodopirellula ...
NP_869516     63 ievtsggvqtsrGFLPATIQLRRWLArr------------pGSLIQTFlw-------------haNVLGILNAss----- 112 Rhodopirellula ...
NP_797846     67 ggwcaprwditgWNNLIKQGSALIEKh-------------nIDLVHVNsg--------------gPCQWMSLAarm---- 115 Vibrio parahaem...
NP_953025     56 glrverfrmrpgANIAGAFSVLRFAWre------------qCDVLHSHgy-------------kgNILFGFMPral---- 106 Geobacter sulfu...
YP_003610664  77 pawakllkeagrGLLFFSRNARKAFTrhvdtlwrirpnvskIETLFSHggfdtlymnnqpgsneeGYLAAAKLq------ 150 Enterobacter cl...
Q04975       241 gnlfddatiespELRLLLSHLPPVCKygikhlv-phlcerkLDYLSVWqd-------------saCLMIALAAliagvpr 306 Salmonella ente...

Feature 1                                                                                        
AAX20105     112 -------rNVWFCLHGVFSasylghrtgfdrwmkqqkikriyqgRNAVTVSDAVGRDLVEEfalrpaQLKTIYNPFDITA 184 Klebsiella pneu...
CAE06692      98 -----crwPVVVAERNYPPsnpqsliwsl------lrrllypsaALHVVQTQRIADWLHQLgl--ssTSVVLPNPVVWPL 164 Synechococcus s...
CAD74550     108 -----lgvPVVVSERSDPKhqslgraref------lrrqlypkaYRVVCLSDDVAVTLQSQtr---cHTLVIPSAIEVPK 173 Rhodopirellula ...
NP_800918     96 -------kKRIQTEHCSYNrrrdyplfkf------ieyvlywghHYTVSISEKVQEELVKFmpryqhKYRVVHNGVDLNR 162 Vibrio parahaem...
NP_864687    188 ----grpcPRVSTIVSPPEvalplvekrfvwlkrqrlaqayrrsAAVVAVSEAARRSAIRYyglpesLVQTIRNPIDVDS 263 Rhodopirellula ...
NP_869516    113 ------rqPRVAGIRVAEPnslrlave----------rqtlrkvDHVVCVSRAVETFAQQQlnlspdRTSVIPNAVDVDA 176 Rhodopirellula ...
NP_797846    116 -----nhvPLVTQLHCHYTlrdrfs-------------lglhlsPKLICVSKDVGREILRDgyp-eeQLHVVHNGVSLDD 176 Vibrio parahaem...
NP_953025    107 -----rrlPMVTTLHGWTWtggmdrmglye----wldrlslrfvDAVVMVNDAMRRKIDLP------GIHVVPNGIPLAG 171 Geobacter sulfu...
YP_003610664 151 -------aRLIQHCRIEPVlspplvk------------lvnahaTKIIAVSHGVEQVLLQHgir-pdLCTTVNNAIDIYQ 210 Enterobacter cl...
Q04975       307 iqlglrglPPVVRKRLFKPeyeplyqal-------avvpgvdfmSNNHCVTRHYADWLKLEa----kHFQVVYNGVLPPS 375 Salmonella ente...

Feature 1                                    ###                                                 
AAX20105     185 LRAEaead---------serPDGDYLIHVGRFhpGKRHDRLLEAYAQSgi-------dAPLVLLGQGKPEQEQrlr---- 244 Klebsiella pneu...
CAE06692     165 PVQDpilqp------dhfmsSDVRVVLAMGTKpfQKGFDRLLQAFQELapr----ypdLVLALVGVHPDHPDLaa----- 229 Synechococcus s...
CAD74550     174 EFRTrlkpite---rqsdpgQAKCHLVAVGRLerEKGFDRLIRSLGDLpdd----apdWELTIHGEGSQRDHLes----- 241 Rhodopirellula ...
NP_800918    163 FPMTakqah-------diseKATINIGMVGRLheHKDHETLIHAIAKLpe-------cYHLHLAGDGDRKASLqr----- 223 Vibrio parahaem...
NP_864687    264 IRGSagsse------pglepDGSLRLVVVGRMtpEKGHATLLSAIGILakdwpeqlpaLRFRLIGDGPLRGDLesrwkdm 337 Rhodopirellula ...
NP_869516    177 FASAdpidwt-----dlgwpADSPVVLFVGRLhtQKGLEHLQRTVERFape----dshRKLVLIGNGPLQNELa------ 241 Rhodopirellula ...
NP_797846    177 SEAPidika------rlgipANAFTFLSVGSLikRKGFDRLIHAMRMHnyh----qtnPHLVIVGDGEERENLmq----- 241 Vibrio parahaem...
NP_953025    172 EAERpavpldp---rivefcRGGITLGAIGRLspEKGFDILLDAVREVaet----npgVRLALLGEGVERDALea----- 239 Geobacter sulfu...
YP_003610664 211 PLPDrramrq-----rlgidDETFVFGSIGSLipRKANHHTLEALAQFslkh--peakWKMVLVGEGPERDALaa----- 278 Enterobacter cl...
Q04975       376 TEPSsevphkiwqqftqktqDADTTIGGVFRFvgDKNPFAWIDFAARYlqh----hpaTRFVLVGDGDLRAEAqk----- 446 Salmonella ente...

Feature 1                             #                      #                                   
AAX20105     245 -qlAKTLHIDDRVWFKGfQKNPLPWIKg-ARMLVLSSDSEGFGNVVVEALLlHIPVASTRCPgGVTEILTGELARGLAdl 322 Klebsiella pneu...
CAE06692     230 -plQRTGSLRPRIVLPGrVGNPADWYQr-ADLFVLSSRYEGSPNVLLEAMAaGCPCLAVDCPtGPHEVIRHGANGWLLpe 307 Synechococcus s...
CAD74550     242 --lASKLNLASRVKFPGwTRPIWPVYQs-ADCFVLPSRYEGFPSALLEAMAcSTAVLTVDAGgAVREIIDHGRNGWLVtn 318 Rhodopirellula ...
NP_800918    224 --lAQSLNVSPRVHFHGvVSDIPRFLSd-MDIYVQSSHVEGFGLAAVEAMAaGLPVLSSDVP-GLDEVTGSSEYLFEVgd 299 Vibrio parahaem...
NP_864687    338 vlaAGPKDAIHRVEFAGaIQPACSEIAa-ADGLVLPSHFEGLPNVVLEAFAlQTPVIATRAG-GAVELQKSSDEPTCHwa 415 Rhodopirellula ...
NP_869516    242 --tWAKQVSGDRVRVLTwQSNIASWIAa-SRVVVLPSRYEGMPNVILEAMAaGKPVVSSRVE-GSQELIGHDPNQGFEln 317 Rhodopirellula ...
NP_797846    242 --lVTDLGMQDRVHFAGeQTNAGAWMSgnADAFISGAYEEAFGLVVGEAALaKLPIVAPKTG-GIPELFEHNHSALLYpn 318 Vibrio parahaem...
NP_953025    240 --kIRELGLTERVLLPGyVPDANRYLPl-FRAFVLSSLTEGLPMVILEAMLaGVPIVATRVG-GVPEVLDGGAAGLLAep 315 Geobacter sulfu...
YP_003610664 279 --qAQNLGIASHVIFTGfQNTPFDYLAt-FDAFILASKSEGLPRVVLEAMLlNIPVIGSQVT-GTAELIDHASTGLLFpw 354 Enterobacter cl...
Q04975       447 --rAEQLGILERILFVGaSRDVGYWLQk-MNVFILFSRYEGLPNVLIEAQMvGVPVISTPAG-GSAECFIEGVSGFILdd 522 Salmonella ente...

Feature 1                                                              
AAX20105     323 tspala----qtmqsiyhNPPAIDDAALekf------------svVSICQQYRQ 360 Klebsiella pneumoniae
CAE06692     308 rtdgfdlamgietclnqpAECRRLGQAAre-------------irDQFSPAKVQ 348 Synechococcus sp. WH 8102
CAD74550     319 ddaal------ragllhcLTSTELRERFaa-------------qaGEVTDRYGW 353 Rhodopirellula baltica SH 1
NP_800918    300 snlla-------qkvaelCEDAALYNSAshysvnr----aklytiDKFREGYYG 342 Vibrio parahaemolyticus RIMD 2210633
NP_864687    416 vpadpg----slaraireFAEQADQRQLhva------------naDRLIRENHD 453 Rhodopirellula baltica SH 1
NP_869516    318 ddtal------vhslerfLADEDLATQTgqa------------nqSRVRSQFTV 353 Rhodopirellula baltica SH 1
NP_797846    319 qgmagl-----lnaiqlvMQDADLREKLaen------------ayLHASQNLTT 355 Vibrio parahaemolyticus RIMD 2210633
NP_953025    316 rhagsl-----agcvsrlIGDDLLAARLaer------------grHLVETRYAA 352 Geobacter sulfurreducens
YP_003610664 355 sdvsql-----aqhldsiWTDADLRARLata------------arQNVCRNYAI 391 Enterobacter cloacae
Q04975       523 a--------------qtvNLDQACRYAEklvnlwrsrtgicqqtqSFLQERFTV 562 Salmonella enterica subsp. enterica serov...

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