Conserved Protein Domain Family
HemN

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COG0635: HemN 
Coproporphyrinogen-III oxidase HemN (oxygen-independent) or related Fe-S oxidoreductase [Coenzyme transport and metabolism]
Coproporphyrinogen-III oxidase HemN (oxygen-independent) or related Fe-S oxidoreductase is part of the Pathway/BioSystem: Heme biosynthesis
Statistics
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PSSM-Id: 440400
Aligned: 882 rows
Threshold Bit Score: 233.15
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AFY92305       1 Mttlqtllanstytsysyayphk-----------tayrplnppahlstvwaqenksALFLYLHIPFCEMRCGFCNLFTQT 69 
WP_011813201   1 MrdllgslypavtsdplryaftarspvmprqdkqsvsapeipdhwagvaqrepaagKRLAYVHIPFCRGNCLYCGFYRHR 80 
WP_108126249   1 Mqlihhpflkfdqlkpiynftyplfh-----tisddyrgqlnftnpsiteritkarTVSLYIHIPFCDTICSFCPFQKGA 75 
WP_015484528   1 Miikdthwtsqqaspnafperqalmpi----wggkniernqwqslwleqapnallqDGLAYFHIPFCASHCIFCGFYRNA 76 
WP_013745424   1 Mnlrdnglfkfdyqfpvynfffpt----------rgkrvsdenindilgrsnfrinSRALYFHIPFCETICSFCPFTRGA 70 
WP_012696673   1 Maasspachagppaaaplpfasrralmp--mwgqavlppeswlaawntiastplpeRALVYVHIPFCANHCVFCGFYRNG 78 
WP_100257365   1 Mnivgngifafdrqyplynffyps----------sgrsvdsaqlehlfisansvakKRALYFHIPFCDTICSFCPFTRGL 70 
WP_129893950   1 Mltmsldlqinsyatllkfdkqipvynw-yypfvsdehkianpwdiykeltdyhphRRALYFHIPFCETICSFCPFERAS 79 
WP_003787192   1 -----maqtiqfspkkaapnafpdrstlmpiwgglsipndkwhtiwesklphsldeDGLAYVHIPFCANHCVFCGFYRNA 75 
WP_106054355   1 ---------------------mmkqtvlrgmmgfpcrelpephrvweealaadtatRRTLYIHIPYCRSRCPFCPFYLGG 59 
AFY92305      70 NaGKDLVSEYLKTLTREATQVKAA--LG--DSQFARMAIGGGTPTFLNVPELERVFDLAADIMGANLhqIPISVEVSPQT 145
WP_011813201  81 S-AAPRLSRYIDWLIEEIRLDAGQplVG--ERPIQAVYLGGGTPSDLPAEDLARLLEVLREYLPLAAd-CEITLEARVVG 156
WP_108126249  76 YkSADQIDEYMTALFKEIQLKAEF--VNslEGPIRTIYIGGGTPSIMSAAHLQQLGKILKTEFDLTNl-AEFTLECEAKS 152
WP_015484528  77 W-KENYSQIYTDRVISELRYESSLw-RG--QGKIHAVYFGGGTPTALHTEDLVRLIRACYRYLPLAEd-CEFTIEGRISH 151
WP_013745424  71 YkDHDIVDKYVNALIKEIEIKSKIndYf--SIPVKSIFFGGGTPSLLSPDNMIKIGEAIKKYFLLSKd-CEFSFEIEIKS 147
WP_012696673  79 W-NAGLAEQYVDRLVADIEAEAARr-PA--GGSIAAVYLGGGTPTLLPAGQLTRLLQTLRRCLPLAPd-CEITVEGRMSH 153
WP_100257365  71 VkDRSVIDSYVSALLTELSAKANKypIG--SVPINAIFFGGGTPSLLSPDHIRTIGKAIREYFDLSDi-EEFSFEIEVKS 147
WP_129893950  80 YtHKDEVEHYVQALLNEIAYKHKFaaLA--HQPIDTIYFGGGTPSVLEPDQIRRLGEAIHHHFDTRDl-QEFTFECEVKS 156
WP_003787192  76 W-KDDISAGYTDRVIAELKREAEIr-TG--SGKIQAVYFGGGTPTALHSRDLARLVEACYRYLPLADd-CEFTLEGRMSH 150
WP_106054355  60 A-GEEETAEYVRLLRLELERWGEl--AG--RFPVNAVYFGGGTPSDLGAESLVSLLDAVRKNYRLAAd-CEITVEGRIDG 133
AFY92305     146 ATTEKLTLLKQRGVDRVSIGIQSFIPAETAAAGRPQTLDNVYAALDRIHSVGFPTLNLDLIYGLPGQSIDSWLKSLQIAL 225
WP_011813201 157 LNEEKVRAAFAGGVNRVSVGVQSFDTEVRRRQGRIATAQEVAERLALLSSEEQGAVITDLMFGLPGQDMDSWHRDLDSCQ 236
WP_108126249 153 VTEEKLIAARNIGVNRISFGVQTFSTRFRPLFDQTATFDDIENTVRWSQE-IIGNVGFDLLYGMHDQSAEELFYDLKRAT 231
WP_015484528 152 FDIDKAKACIEAGVNRISIGIQTFNSEIRKRLGRKHSGEEAQTYLKALSEL-NAVIVADLIFGLPNQTDDIWQNDIEIAT 230
WP_013745424 148 LSFDKVAAMKEMGVTHPRFGLQTFDSNWRKLFNLTSTYEQINFAADLLNK-NFKTVLFDILYGMNGQDEEELIRDLEKAI 226
WP_012696673 154 FDAGKVDACLAAGANRFSIGVQTFDSAIRRRLGRKHAGDEAAAYLAWLARHSQAVVVTDLIFGLPGQTEAVWQRDLDTAL 233
WP_100257365 148 LTKDKIDAMKEIGVSHPRFGLQSFSKRWRDLFTLTATLEQISSAIELLKH-NFNTVSFDLLYGMSGQDEAELLKDLTAAC 226
WP_129893950 157 VTLEKLQAMSEIGVNRISFGAQTLNPKYRELFDLTATVEQIQQVAAWTNE-RFPYTNMDLLYGMAGQTLDELIADVNGYL 235
WP_003787192 151 FDDEKIQAAISAGVNRISIGVQTFDTTIRRRLGRKHSGDEARAYLEKLCSY-DVITVADLIFGLPAQTDKIWQNDIAIAS 229
WP_106054355 134 FEPEKARRLAAHGANRLSIGIQTFDTELRRRLGRVSDRRAILGRLEALAAINEFSLVIDLLYALPGQTAARWEADLATLL 213
AFY92305     226 -KFAPEELYLYPLYIR-PLTG-LER------SRRE--WN-DERRDYYRHARDFLLASGYEQVSMRMFRSRH--------- 284
WP_011813201 237 -ELGLDGLDTYALKLI-PGTP-LQKqvergsIEQP--AGlPEQAAFYAEAVEALTAAGWRQISNSHWARTP--------- 302
WP_108126249 232 -ELKPEAINLYPINNI-SITPkLHKsyanegMK-P--SSlAHRQMMRLISDTFMRGCGYAPCNGHTYVKEAnqlplnnar 306
WP_015484528 231 -SLPISGLDIYAFNNY-PFLP-INRliehgkLPAP--AGfDTQSLHYAYAVEKLKAQGWQQVSNNHFAFPN--------- 296
WP_013745424 227 -ALGTSNIDIYPIDNVmTQAK-LHKair--drgLPltTA-TRKFSMNMLIDSYMRSKGFMPHNGHGYVRVDevdqsv--- 298
WP_012696673 234 -SLGLSGIDVYAFNLY-PHLP-VNRmiekgaLPPA--PGlAEVAAQYGLAHQAFTAAGWEQLSNSHFGAPG--------- 299
WP_100257365 227 -DTGCSNIDIYPIDNVmTQTS-LHKslldlqCE-Pt-SA-VRKFTMNLLVDEYMRSRGYAPHNGHGYRKTDvynrdkv-- 299
WP_129893950 236 -ALGTTSIDCYPLNNA-STQRkLHQafreagrH-Pl-SA-STKLSYRLFLNEYLRAHGYVPINGYSYAKQTqetwgqrvv 310
WP_003787192 230 -QLPLSGLDTYAFNCY-PFLP-INRmiekgaFPKP--LGfDQQSQQYAYAVAELERLGWNQVSNNHFAYPN--------- 295
WP_106054355 214 aATRVSGLDLYRLKVS-DTLP-LAAairagkLPPV--PDdETAYAMHLAGVEAMRSAGAVRISPVHFAFEA--------- 280
AFY92305     285 ------A-PnLDAPVYCCQADG--MVGLGCGARSYTSSLHYSSeyavgmtgiQEIIANYTKQE--DD-SP-GEtlrerfn 351
WP_011813201 303 ------R-ErNLYNLLIKSGAE--TLAFGAGAGGSREPYSYAN---------TPDLEAYERAV--SR-GD-KP------- 353
WP_108126249 307 mssanhF-RyHKYLHGYQDDy---VVGFGASAQSILGNLVTRA---------DPNRSRYITDI--AEqG--TP------- 362
WP_015484528 297 ------RgErNRYNTLVKSNMP--CLAFGSGAGGNFGGLSYQV---------QSDLKTYLDS---PL-DQ-KS------- 347
WP_013745424 299 vtnkysF-IyHEHVYGYSDH-D--LHGVGVNAVSSIREHTITN---------TSSRQNYINSM--MN-GK-IP------- 354
WP_012696673 300 ------RgErNHYNRAIKSGAT--CLAFGAGAGGNHAGLSYAV---------EPDVAGYIGS----T-GS-KP------- 349
WP_100257365 300 iyegytF-QyHEHVYGYHDY-D--LLGFGVNAISSLFGMTIQN---------PTSRSRYIEAY--TR-TReI-------- 355
WP_129893950 311 vqhtptF---RYHDLVYGYG-DecLDSYGVGAVSMFGSRVTSG---------IANRAEYMDRLlgKS-DK--Pw------ 368
WP_003787192 296 ------RgErNRYNTLVKSNMP--CLAFGSGAGGNFGGLSYQV---------QNDLQAYLSG---SL-HE-KS------- 346
WP_106054355 281 ------R-ErNLNNTVSSSKQV--CLQFGMKAVGRLAGRRFMQ---------HSEFRSYRELV--SA-GR-KP------- 331
AFY92305     352 wVNYGYQLDLDDRQRRFLIQSLLQSEGLD-LNDYQ-QTF-HTD-ALTDFP-----QLNDLLTLELATWEV--Gegetgsn 420
WP_011813201 354 -VAMMRVSDALQPLRDALMGGVEVg-RLE-VPALR-ARM-PMP-VRADPRpg--qLIERWVEAGLVVWSG--E------- 416
WP_108126249 363 -TVHFNWVPAAQQASKALCMRLPYSGYAD-KSRIDwENV---DpVT--YQn-----LTNVIRAGLVTEDHf--------- 421
WP_015484528 348 -LSFLSKHGEHKALLGVIQHSMELg-YLD-TTPFE-QN--------AKAEk----LLQQWEALDLLKREK--N------- 402
WP_013745424 355 -MT-INKHSKilDEMKALIMRLPYHGEVE-KSKIDm-----IN-IpLSLQe----KISQLKSHKLITEDK--E------- 412
WP_012696673 350 -LARLARLGEHHGWVSRLQGDVEAg-RLD-PAVLP-HP--------EQLAg----SLARWQDAGLVTPEPagT------- 406
WP_100257365 356 -VVKVRTHPEvlDYARPLILRLPYHGFAD-KARIAfNKIpGV------LLe----RIEQLVGIGLIRDES--T------- 414
WP_129893950 369 -FNAWHVLNDAE--KGIVYFPYRG--TLD-KKRIDwERV---D---AETRe----TLELAVKQGLAIDKG--Ew------ 424
WP_003787192 347 -LSFLSKHSPQKEILGVVQHDIELg-FLD-TKLFS-GS--------DEAQk----LLQQWQSLSLLEIDDksG------- 403
WP_106054355 332 -VKSAGLLPPDFAACGELAGQIYRp-MRIfPGRVA-AAA-PAT-VRERVEtavrsGAEHWAERGFLTAEPg-G------- 398
AFY92305     421 pkssinpppkiplgalpwsgnptgahpqnpksKIILTPAGVE-VSD---T----LGVW--------L----Y---SP 474
WP_011813201 417 --------------------------------DLHLTVAGRF-WAP---N----LISG--------F----Q---QI 438
WP_108126249 422 --------------------------------NLELTQLGWQ-WYS---SltffLLPQidksiidgF----I---DD 455
WP_015484528 403 --------------------------------QVYLNTSGRY-WSP---T----LIRK--------L----M---LT 424
WP_013745424 413 --------------------------------RFYLTKLGWY-WYT---NimfwLMPEseqiamkhFvakhLnteGK 453
WP_012696673 407 --------------------------------GWQLTPAGRF-WGP---T----LTRA--------V----V---DT 428
WP_100257365 415 --------------------------------HYRITKAGWYnYVNmmyF----LMTQterqcldnIvatqLetpDR 455
WP_129893950 425 ---------------------------------YEVTETGWFnYVDleyM----LMPRwhrqhlanL----V---DR 457
WP_003787192 404 --------------------------------IAHLNTSGRY-WSP---T----LTRK--------L----M---FA 425
WP_106054355 399 --------------------------------GFALTERANF-SHR---E----MASD--------L----M---ER 420
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