1YY3,1VKY,1WDI


Conserved Protein Domain Family
QueA

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COG0809: QueA 
S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) [Translation, ribosomal structure and biogenesis]
S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) is part of the Pathway/BioSystem: tRNA modification
Statistics
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PSSM-Id: 440571
Aligned: 789 rows
Threshold Bit Score: 273.43
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1YY3_A         6 K--VDLFDFELPERLIAQVPLEQ----RDASRLMVLDkhTGELTD-S-SFKHIISFFNEGDCLVLNNTRVLPARLFGTKE 77 
AKM78414       7 Ki-LKEYDYAFPETLIAQKPASP----RDSAKLLVYDrnADSITE-T-TFAHIGEYLPKGAVLVFNQTKVLPARLTVTKP 79 
AKM81318       7 KdiLAKYDYPLSENKIANQPIFP----RDHSKLLLLNrqTGAIED-H-FFYELTDLLNADDVLVLNETKVFAARLLGKKQ 80 
WP_012476722   2 Df-LNEFDFHLPEEQIARFPAKN----RDESRLLLVDraNETFKE-ApFFRDIRNWLKPGDVLVYNETKVSYRRVYLQVE 75 
WP_013178995   4 T--LSDLTFERPEHLQATEPPEQrgvpRDAVRLLVSTp-eG--HHgS-CFANLANFLEPGDLLVVNRSATLPASLPAEG- 76 
NP_714746      5 D--LKEFEFILSEERIARYPVAN----RDESRLMVLDvnTGTISS-EpSFKNVISYLKEGDLLVANHTKVSKRRVYLRSK 77 
WP_014801984   8 E--YADLNFDLPEELIATHPVEP----ADHARLMIIDrvRGTITH-S-RFDKLSEILRAGDAIFYNATQVEARRVYLKKP 79 
WP_015120300   1 --mSTPFTFLLPAELSAKEPPERrgiaRDGVRLMTINrnSGEVDH-S-RFNGISEFLRPGDLLIFNTSRTLPASLQGCDC 76 
WP_041191090   2 Q--LADFHYDIPEKLIATTPPTV----RGDARLLVLDrqSGTVSD-R-HYPDIVDYLGLGDVLIINDTKVIKARLITTKQ 73 
WP_082726649   2 L--TARLDFHLPESLFAARPPEArglaRDQVQLLVLDagRRSWQH-A-RFTDLPAFLHPGDLLVVNASQAIAASLPARHG 77 
1YY3_A        78 dT----G-AKVELLLL-KQE---------------TGDKWE---TLAKPA------KRVKKGTVVT-FG-----D--Gr- 118
AKM78414      80 -T----G-GTARILYI-AQ----------------EGDV-----IRAMSD------RKLEVGTNVR-IT-----S--G-- 115
AKM81318      81 -S----G-GKVELLLI-KQI---------------SPNSFE---AISKPG--------LKLGQKLY-FPrrtylDdaGnl 126
WP_012476722  76 -S----G-RIHEAIFL-DTLe-------------dNANIWS---CILKNR------AKLRLGENLWpV---------Gf- 116
WP_013178995  77 ------GfGSFVLNLA-TRYgr-----------gpNAETWL---AEPRWSfaepgpLPLALGDVVT--A-----G--G-- 124
NP_714746     78 -T----K-ARIHEAMFlEE----------------KESLWK---CKIRNS------KKLKMGEQLC--------D--E-- 114
WP_014801984  80 -D----AeKTFECVFL-KSVpppdlpplagggaegRGGTWQ---VLMRGI------RRLKDGQVLQaVK-----D----- 134
WP_015120300  77 -Tl---D-KYLEIRLA-QHL---------------PDDSWL---ALLMCQqgnpfaCGLQEGMNLD-FG-----E--G-- 122
WP_041191090  74 -T----G-GTRELVLV-EKHg--------------RSDDWHthkVIYR--------RKLAVGDKLS-VG-----A----- 113
WP_082726649  78 -SgphtG-LPFRIHLS-TPLppweaq----thglpSREAWI---VEPRTArgi-pgePIAPGEEVD-IP-----GpkGga 140
1YY3_A       119 ---------LKAICTee---lEHGGRKME--FQYDG-IF-YEVLESLGEMPLP-PYIKE-Q--Ld--DKERYQTVY---- 172
AKM78414     116 ---------LFFNVAk----qEGKYYLLKpsFPLQ--QL-NTILDRHGITPIP-PYIKE-SplNereLRKKYQTVF---- 173
AKM81318     127 msdldasdfLQAEVVfr--deQSAKVRVE--FNQTnaSL-LAEIDLCGFTPLP-PYIHPiQ--SeetIKAEYQTVY---- 194
WP_012476722 117 ---------KEFPFVye--skDNELSLLR---S-Er-TItDLDFEVFGTIPIP-PYLKR-K--AiedDKFRYQTIF---- 172
WP_013178995 125 ---------LRATLVhpy-pgLPRLWFVR--FDg---DV-GAAMQRLGA-PIRyGYVARa------yPLATYQTLF---- 177
NP_714746    115 ---------KTKQILftierkEEEFVFLK---P-Kh-SLqEEDFQQIGEIPIP-PYLKR-N--AdseDEIRYQTLF---- 172
WP_014801984 135 ---------PAFEFLlh--raDDKIFVTTh------rPLgAADFARIGEMPIP-PYMRR-A--AtadEADTYQNFFkhqi 193
WP_015120300 123 ---------LTAKVEnqd-ihIPRLWKIS--FSLAgtQL-MDSIYRLGN-PIRyEYVSKp------wDLDYYQTVY---- 178
WP_041191090 114 ---------DTLTVEel---lDGGMAIIK----SER-DL-LQIAEEHGSVPLP-PYMRR-D--AtpaDIERYQTIF---- 167
WP_082726649 141 --------lARVRFVapy-rsFARLWVAG--AGAq-eAL-LEVAARVGE-PIRyPYLEGr------yPIRTYQTVY---- 196
1YY3_A       173 ---SKEIGSAAAPTAGLHFTEEILQQLKDKGVQIEFITLHVGLGTFRPVSADEVEEHNMHAEFYQMSEETAAALNKVren 249
AKM78414     174 ---AKHAGSVAAPTASLHFTDRLLKKLQKQGVDIRFITLHVNIGTFAPLTQEHLDTGALHTESFSIDKQTANFLNKAkee 250
AKM81318     195 ---AKEEGSAAAPTAGLHFTQELLDKLKEKGVQIEKITLHVGLGTFAKLTSENLKNKTLHSEYYEISTEVVARLNQAkka 271
WP_012476722 173 ---AKKSGSVAAPTAGLHFTDSLKLELIQLGIQFVPVNLQVGYGTFRPLTTEQWQTKTLHKERYEITDESASQLNSAkke 249
WP_013178995 178 ---ADAPGSAEMPSAARPFSKRVLRCLAARGVGVARITLHTGVSSLEVTEYK-AARHPLPPEPFEVPPETADAVRETkaa 253
NP_714746    173 ---AKTPGSVAAPTAGLHFSENIFKTLKEKKIQFCTLELKVGYGTFQPLTEENFQNQKLHKEEFFLEESSAQMLNLAkke 249
WP_014801984 194 aekEKVQGSAASPTAALHFTTGLHMKLREQGVDLYPLCLDIGYGTFAPLTAENFSQGELHAEHYYIPPLTAEKFAGAv-- 271
WP_015120300 179 ---AKEPGSAEMPSAGRAFTWKLLFDLKRKGIETAQIVLHTGLSSYMDDELDAL--HPASEEEYFISETAAKKINRVrqe 253
WP_041191090 168 ---AREQGSVAAPTASLNMTEETLSRLRDKGIVVVYATLHVGLGTFLPIRVEDVTDHHMHKEYFEIPAVTVSAIRDAkak 244
WP_082726649 197 ---GDVPGSAEMPSAGRPFSRRTLQRLRAQGVEVARIVLHTGVSSHEI-ETPLVDEQPTYPEPFEVPPATAAAVNSArqr 272
1YY3_A       250 gGRIISVGTTSTRTLETIAge--hdGQFKASSGWTSIFIYPGYEFKAIDGMITNFHLPKSSLIMLVSALAGr-------- 319
AKM78414     251 gRPIIGVGTTVVRTLESACi----dSQLKRLTGETRIFIQEGYRFNFIDGMVTNFHVPQSSLLMLVAALIGk-------- 318
AKM81318     272 gKRIIAVGTTSTRSLESAVllseskKELLATAKETNIFIDPPYQFNFIDALITNFHLPKSSLLMLVSAFISkpnsqadfn 351
WP_012476722 250 gRRIIAVGTTSLRVLETVFds--qqQKFKVGLGQTDIFLSPGDNIESVHGLITNFHLPKSSLLLLVSAFANs-------- 319
WP_013178995 254 gGRVIAVGTTVVRALESAWd-----GTMKPARGFTRLYLHPGRAVNVVDGLLTGFHDPKASHLAMLYAVAGq-------- 320
NP_714746    250 rRRIFSIGTTTLRALESAYdp--vtNTFCSGPGVTELFILPENRLQSCQGLITNFHLPGSSLLLLVSAFAGk-------- 319
WP_014801984 272 tGRKIALGTTSLRCLISYQr-------sGKAEGETALFVTPRDNVSGIDGLITNFHLPQSSLLLLTAAVCRr-------- 336
WP_015120300 254 gGRIIAVGTTVVRALESAVdi---eGLIKPQHSYTRLHISAEHQLKIVDGLLTGMHEPEASHLDLLTAFLSa-------- 322
WP_041191090 245 gKRVVALGTTVTRTLEYAHeai-laGPPRDLSGEADIFMYPGYSFKIIDGLITNFHMPDSTVLMLTAAFAGw-------- 315
WP_082726649 273 gGRVIAVGTTVVRALESCAsa---dSSVRPARGFTDLFVSPARPVRSVDGLLTGVHAPRSSHLAMLSALVDp-------- 341
1YY3_A       320 ----ENILRAYNHAVEEEYRFFSFGDAMLII 346
AKM78414     319 ----DTLFKLYKIAIKRKFRFFSFGDGMLIY 345
AKM81318     352 nfldSSIGQAYQHALESDYRFFSFGDAMFIQ 382
WP_012476722 320 ----RLVMNAYQYALQNQFRFYSYGDSMFLF 346
WP_013178995 321 ----ALVRGAYAEAVREGYLWHEFGDSHLIL 347
NP_714746    320 ----ELILKAYQKAIQEKFRFYSYGDAMLIL 346
WP_014801984 337 ----ELLAQAYRAAIRERYRFYSYGDAMLII 363
WP_015120300 323 ----EQIQVAYEDAVQRGYLWHEFGDLNLIL 349
WP_041191090 316 ----DKLKPAYEHAIDKSYRFFSYGDSMLIL 342
WP_082726649 342 ----ELLLASYEDAKSRGYLWHEFGDSNLIL 368
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