Conserved Protein Domain Family
deiodinase_rel

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NF038285: deiodinase_rel 
deiodinase family protein
Members of this protein family are related to iodothyronine deiodinase, a human selenoprotein. Some members of this family (although not of the seed alignment) likewise are selenoproteins, with the selenium-containing motif GSYTUPPF.
Statistics
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PSSM-Id: 468451
Aligned: 39 rows
Threshold Bit Score: -1
Created: 25-Apr-2023
Updated: 3-May-2023
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_145273155     71 STPSGEr-PEWLLMFADILQGRQLDAADGWFSRPtgGTRYGWDWTRERFDGDG-DGVVAAREWTGPAEDFGLVDADGDRV 148 Tautonia pla...
7_ncbifamImport   1 SAFRGQttPEAAEMLIAIARGSRMGPGEGWFHPG--QGRYGWKWLADKHGIKL-RESIPRAKFAGSEALFARLDRNKDGE 77 
3_ncbifamImport   1 RAFAGRtpPEAMRMFLSIQRGSRMGPGEGWFGPA--QSRYSFAWLAERHGVAP-ADGIEADKFQGEPEWFARLDRNRDGK 77 
OYW23770         39 RAYSGRtaPEAMRMYLAIVKGSRMGAGEGWFGPA--QTRYNWDWLVKACGVDA-DGGIPADKFPGTAAWFEKLDRDRNGR 115
8_ncbifamImport   1 RAYAGRkpPESVRMLLAIAKGSMMGPGEGWFGPA--DSRFSYEWLARET-GVEgK-AIGRDDFHGKAHWFARLDRNKDGR 76 
RLT06990         76 AAYEGKeiPEAVAMYLVIVRDGQLDGTHGWFGPA--KSRFSWQWLADKNGVPA-DGALPKDKFQGDPTIFKMLDRDRDDS 152
RLT21913         60 AAYEGQemPEAVAMYLVIARDGQLDGTNGWFGAA--QNRFSWQWLAERHAIAP-DQPLAADSFHGPEAIFKQLDRDHDGS 136
GDX92332         53 KAYEGRriPEAVSMYLVIARGGQLDGTAGWFHPA--ASRFSFEWLAGHQKADP-QQPLTRDHFMGQERIFEQLDRDHDGS 129
WP_103296291     40 SAYENQrmPEIVRMALAILRGSQMGPNGGWFGPE--ESRYSWQWLASLHGLSE-SDAIERAAFQGDESWFEILDRDRDGK 116 Rhodopirellu...
6_ncbifamImport   1 QAFAGRpyPEWLQMYLAIAKELPLGPETGWFGPG--QSSFGWDWLADFCQADP-TAGITRGNFPGPVLWFDLLDRNRDGR 77 
WP_145273155    149 LTGADFEWPEHALAGGPGVAL---YYLADADANGKVTRAEFLQLFDRLDgGGIGFLSRDELKGAFDPgtmnrlmmaggIK 225 Tautonia pla...
7_ncbifamImport  78 LRADDFDWSDRSFYAQQTYMIsfwFYRINREADGKLTREEWLKFFDEAA-GGKDHLTTTNLREALFTm----------PP 146
3_ncbifamImport  78 ITGDDLDWSDRNSWVQHAYVAnrlFRRMDPNGDGKLAREEWLAFFDAVA-QGRDEVNSEEMREAWLA------------G 144
OYW23770        116 ITQDDLDWSERNPWVQYAYMTnrlFRKIDPNGDGRLQRDEWLAFFDAAA-NGKEAVTAGELRDYWLA------------G 182
8_ncbifamImport  77 ITPDDLDWSDENPWVQQAYFInrlFRRMEPTGDGKLTREEWQAFFDKAA-GGKDHLVSEDLRDALLAg----------VS 145
RLT06990        153 ISGSDLDWSDNNPWVRQSYMIgrmFRRIDPSGDGKLTTEEWQAFFEKIA-GDSDTIRAEQLRDA-LI------------P 218
RLT21913        137 ISGLDLDWSDGNPWVRQSYMVnrmFRRIDPSGDGKLTAEEWQAFFEKLA-GEEKTVRPEQLRDA-LI------------P 202
GDX92332        130 LTGFDLDWSDSNPWVRQSYMVnriFRRMESDGDGLLTADELNAWFGKLS-RDGQPIRFEQFRDA-LV------------P 195
WP_103296291    117 VTAEDLDWSDSSLWVQQTYQAnrlFRRIDKSGSGKVTREAWLAFFDRMT-GGDESFGFEAFRDSVLG------------N 183 Rhodopirellu...
6_ncbifamImport  78 ITAEDLDWSPGAWWVQTAAVIqrlFRRMDQNSDGRLTREEWIGFFDTAT-QGAGHALACDLRDQWLS------------G 144
WP_145273155    226 GGGPPPNpnGPSKSTLVRGLFSQEIGSLWPGPGVDEPAPDFTLPSVDGDRDVTLSsyQERTGKPVVLIFGNFTCGPFRSQ 305 Tautonia pla...
7_ncbifamImport 147 PKKGTVPdeP-TAEMLVRGLFRGEIGSMNEGPKLNDAAPDFTLKARDGKDRVHLS--DHFGKKPVVLVFGNFTCGPFRTI 223
3_ncbifamImport 145 LSSGFLPgdAPTPDLLLKGLFAGEVGSLQEGPQVNEPAPDFALKTHDGSRTVRLS--EVIGSKPVVLVFGNFTCGPFRSM 222
OYW23770        183 MTSGFLPgdAPSKEVLLRGLFASELGSLQEGPQVGDPAPDFRLQTQDGKETIQLS--KVVGQKPVVLVFGNFTCGPFRSM 260
8_ncbifamImport 146 P--SFLPgdAPSPDVLIRGLFAGEIGSLNEGPKLNEQAPDFTLKTFDGAKTIRLA--ELIGKKPVVLTFGNFTCGPFRSM 221
RLT06990        219 PGNGFSPgdMPSKETLIKGLMAGEIGSLQEGPDVDELAPDFELRPLGGGEPIRLS--DRIGKKPVVLVFGNFTCGPFRST 296
RLT21913        203 P-SGFSPgdAPAKETLIRGLMAGELGSLQEGPDVDQPAPDFELSPLGGGDPIRLS--DRIGKKPVVLVFGNFTCGPFRSM 279
GDX92332        196 PGSGFSPgdMPSKEVLINGFLAGEIGSLQEGPGLNDSAPDFTVRAISGGDTVKLS--DRLGKRPLVLVFGNFTCGPFRSM 273
WP_103296291    184 SPAMAMPtdMPTREMLIDGLLAAELGSPFEGPKVGDTAPDFCLQTHDGGQTIRLS--EMIGSLPVVLVFGNFTCGPFRSM 261 Rhodopirellu...
6_ncbifamImport 145 FSGGYLAgdAPSRDMLVQSLFTGELGSRFEGPRVGDPAPDFVLRTPDGGREIALV--EVLGPQPVVLVFGNMTCGPFRSM 222
WP_145273155    306 AGNVEKLYRRYRDRVGFLLVYVREAHPTDGWHMFDNFRQGYNLDQPTTFGRRVEVAQQCRATLDLDIPMLVDAIDDPVGT 385 Tautonia pla...
7_ncbifamImport 224 YPRVDEVAQRYKNDAIFLFIYVREAHPTDGWRMGSNEEAGVSFAQPRDYGERATMANRCGTRLKMNVPVLVDEMDDRVGH 303
3_ncbifamImport 223 YPGVEDIYRRFKDEAVFLGVYVREAHPTDGWKMESNAKVGVAVAQPKTTAERVDVAQQCHRLLKPSIPLLVDEIDDPTGN 302
OYW23770        261 YPEVDELARRYSDVATFLGVYVREAHPTDGWAMTSNEKVGVKVAQPQTFAQRTAVAQQCYARLKPSIPLLVDDINDPTGN 340
8_ncbifamImport 222 FPGVEDIHRRFADEATFLAVYVREAHPSDGWKMESNSRVGVVVAQPKTFAERTAVAAQCHQLLKPTMPLVVDEINDPVGN 301
RLT06990        297 YPAVEAVRERQKDNADFLMVYVREAHPTDGWAMKSNDKVGVSVAQPTTFEERHAVAEQCAAKLNPSMPLLVDDINDTVGN 376
RLT21913        280 YPAVEAVKVRQQDNADFLMVYVREAHPTDGWVMKSNEKVGVAVAQPTTFVERQAVAEQCAAKLNPSMPLLVDDISDTVGN 359
GDX92332        274 YPTVEAVWNRQKEHADFLFVYVREAHPTDGWAMKSNEKAGVLVSQPRTFEERQLVAEQCVAKLKPSIPFYVDDIADTAGN 353
WP_103296291    262 FTVADAIAKQFDSQAKFVGVYVREAHPVDGWRMGSNDAVGIEVTQPQTYDQRVEHACRCRKLLNASMPMLVDEIDDPTGH 341 Rhodopirellu...
6_ncbifamImport 223 YPEIDRMASRFSDRARFLGVYVREAHPTDGWCMLSNECVGVSTRQPKTDEERRATASRFCDLLQPTLPWLVDDLQDSTGH 302
WP_145273155    386 LYSGMPARLYLIDRDGRVAFKSGRGPFGFKPEELEQAIALMQSS 429 Tautonia plasticadhaerens
7_ncbifamImport 304 AYSGMPARLYVIDKAGKVAYKSGRGPFGFKPEEMEQSLVLLLLD 347
3_ncbifamImport 303 AYSGMPARLYVIDTAGKVVFKSGRGPFGFKTGEMEQALMMTLVD 346
OYW23770        341 AYSGMPARLYVIDTSGRVVFKSGRGPFGFKAGEMEQALLMSLVD 384
8_ncbifamImport 302 AYSGMPARLYVIDRLGKVAYKSGRGPFGFRSGEMEQALVMALLE 345
RLT06990        377 AYSGMPARLYVIDTNGRVAYKSGRGPFGFKPEEMEQALLMLTLE 420
RLT21913        360 MYSGMPARLYVIDTHGKVAYKSGRGPFGFKPEEMEQALLMLLLD 403
GDX92332        354 LWSAMPARLYVIDSQGKVAWKSGRGPFGFKPEEMEQALLMLRLE 397
WP_103296291    342 AYSGMPDRMYVIDRDGKVAFKSGRGPFGFKTGQMAQALVMALLE 385 Rhodopirellula sp. MGV
6_ncbifamImport 303 AYSAMPARLYVIDAAGQITYKSGRGPFGFKPGELEQSLIMTLLA 346
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