1REQ


Conserved Protein Domain Family
Sbm

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COG1884: Sbm 
Methylmalonyl-CoA mutase, N-terminal domain/subunit [Lipid transport and metabolism]
Statistics
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PSSM-Id: 441488
Aligned: 432 rows
Threshold Bit Score: 630.938
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1REQ_A        26 EL-AA-KA-GtGEAWETAEQIPVGTLFNEDVYKD--MDWL--DTYAGIPPFVHGPYATMYAFRpwTIRQYAGFSTAKESN 98 
WP_011754272   1 -MtSS-EA-SgSSEVTTVSGIPLKVSYGPNDVPE--TAAQaaAVLPGEAPYLRGAHAQGYRSKpwRIFQLSGFGNPEDEA 75 
WP_011993145  27 QV-AG------EKPVRNRSGIEVQPLYSPRDWAG--ERYLddLGFPGQYPFTRGIYPSMHRGRtwTQRQLIGLGTPQDYN 97 
WP_015948901   7 QL-DR-HA-GglVRWATQGHIEVKEFYTPEDTAD--RSYEesLGDPGQYPYTRGLYQSMYRDRlwLKSFIVGYATVEETN 81 
WP_013074530  24 yretvkGN-DgGNDYVTDSGIPVNLIYGPDDIAD--FDYLkeSGFSGEPPYVRGVYPNMYRGRlfTIRQIAGFGTPEDTN 100
WP_006523678  11 YL-EG----EkLGRIETPSGIPIKDVYFPAHINN--LNYDndLGKPGEFPFTRGVYPNMYRGRfwTRRFQVGFGTPQETN 83 
WP_041775866  11 vtrEGrQSaN-AEERYSTSGFQTRPFYASADVEGqwLAEEtdFPPPGRFPYTRGFTSGGYRDElwAREMYAGFGSAEEAN 89 
WP_067964486  27 TL-NS-RP-EeKAAYETECGIPLKRIYTAADVAG--IP-AgdLGFPGAYPFTRGAYPTMYRGRpwTIRQVAGFGNPEATN 100
WP_089423298  30 LI-Ge------DKPVKNRSGIEVKPLYWPGSDPD--GAYNekLGFPGADPMTRGIYPTMHRGRtwSQRQLIGLGRPVDFN 100
WP_114928433  11 PQ-AQ-GT-EaQPVFSTQSGVPIQERYGPEALQG--WDPArqLGEAGSFPYTRGPYPTMYRSRlwTHRQVVGLGTAQETN 85 
1REQ_A        99 AFYRRNLAAGQK-GLSVAFDLPT-HRGYDSDNPRVAG---DVGMAGVAIDSIYDMRELFAGIPLDQ--MS-VSMTMN--G 168
WP_011754272  76 ERIRYLLSKGGT-GFIMEHDRMTgDHLYDVDHPEVVArreDVGISGAVILSARDFELALTGIDQSKyfAH-PGGGVS--Q 151
WP_011993145  98 VRVRRIIDAGAT-AISLLPCCSG-FRGIDCDEVDPV----LLGTCGTVVNTTDHMDAALDGVPLGT--IS-TAMND---P 165
WP_015948901  82 EAFKKYIAAGMN-DLRIGGDLNA-QVGLDPDHPSAFN---SISCAGPTVPGLYRFEKILEGIDLEQ--GV-YELGDA--S 151
WP_013074530 101 RRFKFLLENGAT-GTSVVLDLPT-IRGYDSDDPKAEG---HVGAAGVAIDSLEDMEALYDGIPIDQ--VS-SNIVTHlpS 172
WP_006523678  84 ERLKFLFKEGQT-GFTMTIDLPT-SYGFDSDDPISEG---EVGVTGVAISTVEDLEAIFNGFSPDQ--VS-CSLSIR--P 153
WP_041775866  90 RRYRFLIENGATgGVSIALDLPT-QIGYDSDDPMAVG---EVGRIGVALDSYSDIDDLFSGVDLAG--AGhVFSTAN--S 161
WP_067964486 101 QRYKYMIQTGQT-GLSTDFDLPT-LLGLDSDDPMAFG---EVGRVGVAIDTVDDVDRLFDGIDLEK--IS-VSLTIN--P 170
WP_089423298 101 GRIKKILASGAS-ALSIIPCNSV-YRGIDCDEVEPE----ILGTCGTIINTEEDMDICLADIPIDE--IS-IGLN-D--P 168
WP_114928433  86 ERNKYVIEHGQT-GLSNDYDVPT-LIGLDSDDERARG---EVGRSGVAIDTLRDMYDVFDGIDLEN--IS-VSMTIN--H 155
1REQ_A       169 AVLPI--LALYVVTAEEQGVKPEQLAGTI-QNDILKE-F----MVRNT-YIYPPQPSMRIISEIFAYTSANMPKWNSISI 239
WP_011754272 152 HAAFA--LAGYWTVAERRGLELHKLNGTG-QADFFLT-Y----IGCPPlTQIPPAAALRVNCDIVEYAAKVAPKWTPISM 223
WP_011993145 166 SPFTL--LAFTLGVARRRGIDWRSITGTSnQSDYISH-F----IANHQfYRLSLPGSRRVLLDHIEFCRRALPNWNPLSV 238
WP_015948901 152 PSSCLfrYSMLLALMENQEKDISRIRGNA-VNDPIRS-K----LVFGI-RDFTTEINKRICLDFIEFSKKHTPKWHPFSP 224
WP_013074530 173 TTVVL--MAMFVAMAEKRGLPLEKLSGTN-QNDFLMEtT----IGSSL-EILPPKASFRLQCDSIEYASKRLPRWNPVSY 244
WP_006523678 154 PVSAVt-LSMLAVLADRRGIPYKNIIGTQ-QNDPFYQ-MsggpLQTTT-QFFPLDGIIRLNQDIIEFMAKNFPKLNWMVT 229
WP_041775866 162 IAPIV--YSWVLTYCERHDIDPGSFRLQL-QNDPIKE-Y----VARGT-HFLPIEAAVRLATDVVIHSHRTTPGWLPISV 232
WP_067964486 171 SAWVI--YAMFVAVAERRGYDLTKLTGTL-QADPLKE-Y----VAQKE-WIYPVRPAVRLLRDLIMHSAKTTPKLNPISL 241
WP_089423298 169 SPFTM--LAQMLVVAEKRGIDWKKVTGTSnQSDYISH-F----VANHMfYRLSLQGARRVQLDTAAYLAEHVPNWNAFSI 241
WP_114928433 156 PAFIL--VAQYIAAAQQRGFRLDRLAGTV-QNDPLKD-F----YAQKT-YRFSPRPSVRLAADLIEHCAQHMPRWNGISL 226
1REQ_A       240 SGYHMQEAGATADIEMAYTLADGVDYIRAGE-SVGL-NVDQFAPRL-SFFWGIGMNFFMEVAKlRAARMLWAKLVHQ-FG 315
WP_011754272 224 AAYNGADSGLNAYQELAALFACCVSHLDEIV-ARGNvPVEQVAYALgGVSFRVAMDFFEDICKlRVARKMWHRLLTTrYG 302
WP_011993145 239 VGQHMQQAGATPAETMGFTLSSAIQYAQDCI-ERGM-DVDDVLRRF-TFFFDISISFFEEIAKfRAGRRIWARIARErLG 315
WP_015948901 225 NGVDLNQSGMDAVAEVGGVLALGEAVCRELQnSRGI-SVDEFGP-M-VFSMDADSDFFETIAKfRVARRMWARIAKEkLG 301
WP_013074530 245 NGYNLREAGTTAVQEVGCAIANAIATTEELI-RRGN-DVDDFAKRL-SFFWNLFNDFFEEIAKcRASRLVWYDVMKNrFG 321
WP_006523678 230 NAYNLRETGITAVQEGAFALSHAFNIFELAV-SRGL-NVDEFAPRA-SFFCSCGIDFFEEIAKfRAMRRIYARTMKErFG 306
WP_041775866 233 SGSHMKQAGSSPLQEAAFTLANGIAYLADAQ-NKGL-SIPDFHPNL-EFHFCTEMDFFEEVAKyRAVRQVWSRIATErFG 309
WP_067964486 242 SGYHLSDVGGNALQEIAFIMAFTIAYCEEVI-AAGM-DIDDFAPRL-SFFFISHQDFFEQICKfRAARRVYARIMSEqFH 318
WP_089423298 242 VGQHMQQAGATPAQAMGLTLSTAIQYAEDCK-ARGM-DPEKFLERF-TFFFDISISFFEEVAKfRAGRRIWNRLVSDrFG 318
WP_114928433 227 NGYNIREAGSTADQELAFTFAHAIAYIEELL-GRGL-PIDSFVSRF-SFIFNVHNDFLEEIAKlRAARRMWARLLTErFG 303
1REQ_A       316 PkNPKSMSLRTHSQTSGWSLTAQDVYNNVVRTCIEAMAATQGHTQSLHTNSLDEAIALPTDFSARIARNTQLFLQQESGT 395
WP_011754272 303 ItDPRALSLRIHIVTAGSAMTYQEPINNIVRGTVMGMAAVLGGVQSIGVSAYDEALSVPSEQAHRQSLRVQQILMHETNI 382
WP_011993145 316 AkDPACWRFKFHGQTSGVDLTQQQPLNNIARVSVQAMAGILSGLQSMHTDAYDEAIACPSEETARIAVATQNILRDEAQL 395
WP_015948901 302 AqTERAMKLKIGIRTSGLSLQEQNPLNNAARITLQILNCVFGGVNSLDSSCMDEALGLPSFEARMFSLNAQHIVTHEANI 381
WP_013074530 322 AkNPRSYLMRFHVQTGGITLTKVEPLNNIARSAIQGLAAVLGGAQSLHIDSYDEAYSAPTEQAALVSLRTQQIIQVETGV 401
WP_006523678 307 AkNERSWKFRSSVQTAGNSLTTQQPFNNVIRTTMEALASIFGGLQSIQVASYDEGLGLPTEESSRIALRVQQIIGYETGV 386
WP_041775866 310 Vp-EDRLRFRLHAATSGQPLTAQQPLNNISRITLQALAQILGGVEATRTASFDEALGIPTEEAAKTSLRINQIMAYETGI 388
WP_067964486 319 AkKPESMRLRVHVQTAAMSLTKVEHHNNLMRTAIQALGAVLGGCQSMHTNGLDEAFAIPTEEAMKLAIRTQQIIRDEINV 398
WP_089423298 319 VtNPRAKRFKFHAQTSGCDLTRQQPLNNIARVTIQAMAGILGGLQSMHTDGYDEVLSTPTEDSAKVAVSTQNILKHEAHL 398
WP_114928433 304 Ar-PESVKLRMHVQTGGSTMTYQQPEVNLIRGALQSMAGALGGVQSMAVSCFDEAYSIPSQRAQRLSLRTQQVVGFESGV 382
1REQ_A       396 TRVIDPWSGSAYVEELTWDLARKAWGHIQEVEKVGGMAKAIEkgIPKMRIEEAAARTQARIDSGRQPLIGVNKYRLEH-E 474
WP_011754272 383 PAVVDPLGGSYFIESLSAELEERAWAEFDRILDNGGFIQSLEdgSLHRMAGENAVAFQDSITSGDRKIVGVNLGDSDG-D 461
WP_011993145 396 CAVIDPLGGSYYVERLTDQMEAEIEAVIARIDAAGGMYKAAEvgLVQTMIGESALAFQEQLETGERKIVGVNCYQVEE-D 474
WP_015948901 382 PMVADPLGGSYYLEWLTNKIESDVTAYMAEMEANGGIFECMEndWLKGKMLENRRKVQKERQDGKRLIVGVDAFKHPE-- 459
WP_013074530 402 VNTVDPLAGSYYVEYLTREMAEHIRAYIDQIESRGGIIAVVEsgWLHREIAEFAYRTQQDIETGKRKVVGLNYFPSKEaE 481
WP_006523678 387 TQTVDPLAGSYYLESLTKEMEENILELMEKVESRGGMIECIRsgWLENEILRARVKNQREIENDEKVLVGVNKFKVEE-E 465
WP_041775866 389 PDTTDPLGGSFYVETLTGQMAQGMVAELDKIEEMGGALGAVEsgYYAQALAAGAYQQQVALDEGDRVIVGVNKYRSEE-P 467
WP_067964486 399 TSVIDPLGGSYFVERLTHDMETEIWKVLDEVKERGGAIKLVEegWFQQKLADSAYATFKKIDSGEKVSVGVNRHVDET-S 477
WP_089423298 399 CDVIDPLGGSYYVESLTDAMEVEILNVIAEIDAEGGMFKAVEsgFVQEMIGASALEFQDQVDSGEQIVVGVNAFKEDE-D 477
WP_114928433 383 TKVVDPFAGSYYVESLTDETERRADEWLARVDEQGGAIAAVEngWFERVISDTAHRQHLEVASGERVIVGVNSFEESE-E 461
1REQ_A       475 --P-PLD-VLKVDNsT-------VLAEQKAKLVKLRAeRDPEKVKAALDKITWAAGNPddkdpdrNLLKLCIDAGRAmAT 543
WP_011754272 462 --PfGID-GFEGSL-D-------AFERGMARLKDLRAsRDGRHVSRALDRLANTMRSGg------NVMSGVMDAVRAdAS 524
WP_011993145 475 --P-TIPpAERPDP-E-------AMERHVERFKVFKReRSQDAVARALDALARAANSEr-----eNVFEKVVEAAEAgVT 538
WP_015948901 460 --G-PIN-QAIIDS-AyhappldVRMKVLAELKEFREsRDPEKLKSGLMGVYLASKHGe------NVVRPIIDAIKAgMT 528
WP_013074530 482 --T-KVE-VFRYPE-D-------AERMQKEKLAKLRArRDPVKVEQTLRVLREKCHEDv------NILPYVKDAVEAyCT 543
WP_006523678 466 --P-EIK-IHSIRS-De------WGAARAAYLKEYRAnREQKRVAETLKNVELNMKTSk------NMISIIMEALKArAT 528
WP_041775866 468 --R-PYP-RFTGDE-Q-------SEQRQCERLSRLRAaRDADRCRKALEDLRDACAGTd------NVMPAVHAAVGAdCT 529
WP_067964486 478 gsA-EVH-IHPYDD-Q-------CTQLQIDRLNAVRTeRDNGLVKQLLAELAEQAQSDd-----iNLLPKTIELVKArAT 542
WP_089423298 478 --A-SARpFLKRPS-Qv------HMKQQVEQLKKIKAaRDPALLNNALQELRQAARSEd-----iNVFAAEIDAVRAgAT 542
WP_114928433 462 --S-EIE-TFRVGP-G-------SEAAQLERLKEVRAtRDDREVQRLLDVVQETAAAGk------NLMPAVIDAVSAyAT 523
1REQ_A       544 VGEMSDALEKVFGRYTAQI 562
WP_011754272 525 IGEVGDVYREVFGSWKFPV 543
WP_011993145 539 HGEMVGCLRRELGFGHPLI 557
WP_015948901 529 LGEMVGVIRLGYSLPYDNL 547
WP_013074530 544 LGEIQNVFREEFGLWQFPL 562
WP_006523678 529 MGEIHQAMRDATGFKIQL- 546
WP_041775866 530 VGEISGVWRAVFGEHHETR 548
WP_067964486 543 LGEICSALREVWGSYAEPM 561
WP_089423298 543 LGEIVKVLRDELGFGQPLV 561
WP_114928433 524 QGEITDRVLAVDGEYVAPA 542
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