Conserved Protein Domain Family
HerA

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COG0433: HerA 
Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains [Replication, recombination and repair]
Statistics
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PSSM-Id: 440202
Aligned: 690 rows
Threshold Bit Score: 94.2887
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_006289731 117 VVAlTTQEELNaIYsvdegepTIIIGESVr-------EGKRVELPINKFFASHIGIFGNTGSGKSNTLHKLYLELF---K 186
ACR42359     201 atysikekgielgyiegilapslvnrisntkygwrkfsnlkfhlnfdesknynIVILGTSGSGKSSLAKSIIGK------ 274
WP_010978364 186 slsnkgvlvgkiigkigkgssidnafytsnstykwirtdgIYYLDFNSSKNYNVIIIGTSGVGKSTLAKKIVNSl----- 260
WP_013129703 226 rlgralaqlehglpvneykgfpqhwvsrdqpcwywrrvrgDINLPVKSLINTHVVIAGASGTGKSLLAKKLVRE-F---S 301
WP_081758453 367 pssptssqtesipqtppkvdimlgmnqmpsaqygilgeangktigvdldhpqtICAFGLQGSGKSYTLGSLIEMTL---T 443
WP_126449229 172 gqgvwsengggvscvgtvkgeilnnnhgrlwrprwvpvEYPFCIDLQRMRNYNLSVSGTSGSGKSTLIRQIIRGt----- 246
WP_083810718  89 sngeekgicigeiigilkrssfssskistnsnykwisyrskfyinlernknfnIIIVGGSGSGKSHLAKNIIRKg----- 163
WP_011966724 145 nnkvAMAKDIP-VL-------NLLIGNYGdeem-eatLDINs----rSITNSQIIIAGATGSGKTNLLAVLIQQFRmlsT 211
WP_014736977 250 nglnlgtglgvarrgrricpvelkgfeepaedwywaclgAPLKLDPGKLVNSHMIVVGSSGMGKTTFVKGFIKDIA---S 326
WP_013143742 259 KVYq-----------------EIHHYRLkkktwfwraIEKPLYIDLTSLPNRHILITGASGTGKSLLAKHLVLEIY---K 318
WP_006289731 187 SqyrdeifkK-S---R-----FF-----VIDFNGEYTs-------------------------gQfgVspksqKIFdiNT 227
ACR42359     275 Fs-------D-I---S-----YL-----VFDLHGEYEie---------------------------sG-----ERI--D- 298
WP_010978364 261 ---------N-I---S-----YL-----VFDLHGEYEvq---------------------------gA-----KKI--D- 282
WP_013129703 302 Rm-------G-K---T-----VL-----IIDPHGEYRpedi--------------------glgE--A-----RVV--D- 330
WP_081758453 444 Rv-------GnIntlPapragVIfhystTQDYAPEFTsmgqansvaadivrlreqykatpqalkdvlIltpasKVv--QR 514
WP_126449229 247 ---------S-V---S-----VT-----VFDLHGEHRvh---------------------------gL-----HVI--S- 268
WP_083810718 164 ---------N-F---H-----FL-----IFDIHGEYDv----------------------------nA-----KRI--D- 184
WP_011966724 212 Esq-----yP-V---N-----FL-----LFDYKGEFsdiqnshw-------------lalfdvdR--S-----CIL--DP 250
WP_014736977 327 Rg-------H-V---D-----VL-----IFDPHNEYVdlle-----------------------tlgA-----RSI--N- 354
WP_013143742 319 Ky-------G-H---S-----FI-----IIDPHNEYKilrr--------------------yipK--I-----NIV--D- 347
WP_006289731 228 rnp---geGAPLPIKKE------CIl-------DPDILAILFD----ARPaTQLPF-LRRAieqyrkissseqfarleig 286
ACR42359     299 --------ISKNSLNPL------SLngasprqrALEVAYMLRSi--fRLGnLQTID-IFNIimdtyaekgid---endes 358
WP_010978364 283 --------ASKVTINPL------SLfgrspkerALEISLMIKSl--fNLGnLQTIE-LTNLiieayaekgid---endse 342
WP_013129703 331 --------ASEIFLNPL------ELgglnplekAKEFSQTLSLl--fGLGpLQRIA-LEEFlvkayrekgid---vndpa 390
WP_081758453 515 qaehpdipvLPIAFSAA------ELn-------ASHWKFLMGTvg-------nPSLyVRQInglmr-------------- 560
WP_126449229 269 --------GGSVSVNPL------SLlgssprqrAIEVSYMVKSl--fSLGpLQSMA-LTELilqayeekgit---eedke 328
WP_083810718 185 --------ISKISINPL------SLfgqsprqrALEVAYMIKSi--fNLGsLQTID-LSNIivdaygekgif---edder 244
WP_011966724 251 l-------tQPLPFTPfkdftgrSInei--nlySTEMSSALCSidrvSASaNMNNR-LSEAiveayk------------- 307
WP_014736977 355 --------PRQMGINIL------YLglspprerARRLADVVSSf--fNLGpLQRRA-LEELivkayerkgiv---deder 414
WP_013143742 348 --------ASTLSINPL------ELgrlgpkekAYQISSFISTl--fKLGpIQRHL-FADLilevyrlkgiy---pdkpe 407
WP_006289731 287 llislFKDYKDiklssgLVeswfkiandlnSDIhridgnQssyeldygkvnfsikdqgnqdipifsngkisnqlridfye 366
ACR42359     359 swnstPPTFRD------VL-----------LMI------Errk------------------------------------- 378
WP_010978364 343 twnlsPPTFRD------IL-----------ILL------Ekkk------------------------------------- 362
WP_013129703 391 twglpPPSLQD------LE-----------KAC------V---------------------------------------- 407
WP_081758453 561 -tlrgELTLET------LR-----------EAVs-----K---------------------------------------- 577
WP_126449229 329 swslpPPTFRD------VI-----------RL------------------------------------------------ 343
WP_083810718 245 twnlpPPNFRD------VL-----------MLL------Ekkk------------------------------------- 264
WP_011966724 308 -stngtPISFE------LM-----------LKCy-----Qsrm------------------------------------- 327
WP_014736977 415 twtrePPSLRD------LV-----------EIC------E---------------------------------------- 431
WP_013143742 408 twsnkPPTIHD------LL-----------EFC------Q---------------------------------------- 424
WP_006289731 367 eklktayskldneierlryflqfqrifdeAFKSLMPEYINpLFRRIDvAL-ADlKPVV--------EivdnIEsEfATLN 437
ACR42359     379 ---------------------------klVENSQDLSRLSsIEPYIQfl----sNQILsgnsldmkKi---F----EGNI 420
WP_010978364 363 ---------------------------klATTSQDIIKYQsIEPYIQfl----sSSIFnnsnvnisEi---L----ENNL 404
WP_013129703 408 ------------------------------ESAEPFEEYSrICPYVKml----aRHFPkqspisltSl---L----DRPV 446
WP_081758453 578 ------------------------------------SELGaqKKKMAqqrldfaCEYIddtq-rlqAl---LR-P-GRLI 615
WP_126449229 344 ------------------------------ATARDDGNMSsLLPYVTfl----sTGPFnaqgidldEl---L----LQSS 382
WP_083810718 265 ---------------------------klVTTSQELNKIQsLEPYIYfl----aTNTFmdnsinlyDl---I----SDDY 306
WP_011966724 328 ---------------------------------kdaNNDDsISSVLK-QL-VN-AHIFese--dkvSl---I----DDSY 362
WP_014736977 432 ------------------------------SESFEKPSCSsILPYVKtl----eEAFSrphtarggSw--tL----EGSA 471
WP_013143742 425 ------------------------------RLMSDNELYKkIYPYLRil----aDNVFsstnisfyDl---T----KTPT 463
WP_006289731 438 ILSLAH--ANR-N--IKRLMPMLLAKMIYDEQKEAVANN----GGNvccTKHLIVDEAHNILSASsqsegdswqSYRLSV 508
ACR42359     421 ILDFSK--VATdE--LKYILIETILRDFRNYLYRRGISRl---------WKFLVIDEAPFILGKE---------T-GLEI 477
WP_010978364 405 IIDFSK--IPTnE--IKYVLIETLLKSIQNTMYISGISNl---------KKIIIIDEAPFILSKE---------S-GKQI 461
WP_013129703 447 ILRLNK--VASdF--SRTILVETLLYSILSAMYSRRL-W----------DLVVVVDEVRAVLPGG---------V-GDRI 501
WP_081758453 616 IVDLRDeyIEKvE----ALGLFVVMLQIFAEAtw--------qGETf--sKLVVFDEAHKYIGN----------DGLVAG 671
WP_126449229 383 VIDLSG--LPSdE--VRYVVMETLIRSVVSLMYRQGPRPl---------WKLLIIDEAPFILSKE---------S-GLQL 439
WP_083810718 307 VLDFSK--VTIpE--IKYVIIETILRSILAYMYISGQSNf---------RKMIVIDEAPFILSKE---------S-GEQL 363
WP_011966724 363 IIKMDG--YPK-DgpIAKAIVYFLMSKLNNIYELLDKQAvndeVVQi--RHFSIIDEAHYMLDFDn----------RP-- 425
WP_014736977 472 VINLSD--IPDdY--TRFIYVDTILQLVLSEMYSRSVKR----------RLAIVLDEAALLMRSR---------A-VEDV 527
WP_013143742 464 IVTLNG--LSSdF--VKALYVNALLQRILDSMYIGELRK----------KLMIVLDEAYMFLRKG---------L-SRNI 519
WP_006289731 509 FEEIIKEGRKFGFFLTLASQRPADI---SPTIISQIHNFFIHRLVNDTDLRMLEntmp---tldrNSY----SQISSLGQ 578
ACR42359     478 VERLFAEVRKFGVGMILISQITENI----ENIFQNSSYIFIFNVVEPKELDYLSralg---gsdrDRYeaiyQAIRSLER 550
WP_010978364 462 LERLFAEGRKFGFGFIIISQTSEYI----KELLANTSYFFIFNLVEPKELDYASkllg---gsdtQLYaaiyETLQKLPR 534
WP_013129703 502 LSRLFSESRKFGISLIVISQDVKNI---PRTLLSNAGLKIFFNINEPDSLEYAVksitg--vstsDKEiavsTALRSLKT 576
WP_081758453 672 LIEIVREMRHKATSILVASQDPPSV---PVALIELSTQLYLHRFNSPAWLKHIQkan-----talLHLg--pKDLSQLAP 741
WP_126449229 440 LTRLMAEGRKFGVGIVISSQSIKYL----KGLISNSARVFVFSTVEPDDLYYASqlls---agqrNVEewlrSRLVKLKK 512
WP_083810718 364 MERLFAESRKFGFGFILISQSVEYV----RKLIPNTSYVFALNIVDPTEIDFISrlig---gqdpDIFkaiyNSLPKLER 436
WP_011966724 426 LRNLIAVGRNKGLSIILATQNMSSFkskGFDFYANAQYPLIMK-QQTIDDKVIKdlfgvsgqelqEIR----TAIAGLQK 500
WP_014736977 528 MSRLYMESRKFGFSVILVVQNPYLL---PESIIVNSGIRVVFGLGEPRSVSYAArilsp--ggppGRSrlveKTLVNLKP 602
WP_013143742 520 VSKLLMESRKYGLGLIIISQQILAV---PDPVVENSSIKIFFNTSEPKNLEYSSriics--gcdkYGIiaskSALTNLKS 594
WP_006289731 579 GEAIV----TGTa-VQ--V---PILLHVDREeQvtR 604
ACR42359     551 GHVVT----ISGd-SR--D---ILLVKLNSLk---- 572
WP_010978364 535 GYCVT----RDLl-RG--E---IYLLNLT------- 553
WP_013129703 577 LEYVL----DIAg-LN--K---VFIAKNPYInp--- 599
WP_081758453 742 GEAFVwaskATDvaF---Th-gTVKVNCRPRvT--L 771
WP_126449229 513 GTMVT----LDEe-GN--L---FIVDSETA------ 532
WP_083810718 437 GLIIT----RDIl-RD--E---IILVRSN------- 455
WP_011966724 501 GELIIk----DQmaFAlgMgnkYKKINVTHL----I 528
WP_014736977 603 GYYLV----GLLg-SE--N---IFLVSRykptc--- 625
WP_013143742 595 YNYIL----SISg-FN--E---IFIVNEEDIaqnmy 620
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