1UFN


Conserved Protein Domain Family
SAND

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pfam01342: SAND 
SAND domain
The DNA binding activity of two proteins has been mapped to the SAND domain. The conserved KDWK motif is necessary for DNA binding, and it appears to be important for dimerization. This region is also found in the putative transcription factor RegA from the multicellular green alga Volvox cateri. This region of RegA is known as the VARL domain.
Statistics
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PSSM-Id: 460167
Aligned: 58 rows
Threshold Bit Score: 63.3703
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1UFN_A        12 DF-SPTLPVTCGKAKGTLFQEKLKQ-GASKKCIQ---NEAg-DWlTVKEFLNEGGRATSKDWKGVIRC------------ 73  house mouse
EEN59154       1 ---EVAYPVMCGDNQGLLIWKKFICpGIHSRCIK---YNG--MMrTPKEFVVEAGKAGLKDWKRAIRI------------ 60 
Q18624        70 PLnATTVPVTCGYVKGIMHLKLFRCpGIRQACIE---YES--QYlTPKQFTELGGKGRQKDWKACIRV------------ 132 Caenorhabditis ...
CAP28875      91 GDaSPTVPVSCGNVNGKMHLNMFMCpGIHQPCIE---VGN--DLlSPKQFTVRGDKERQKDWKASIRI------------ 153
NP_001317728  76 VSlPPVITVKCGTLTAKMVTKLFTCpGIHQNCIL---IDGetEYiSPKEFTVRANKDKQKDWKGSIRI------------ 140
EFO27974      16 DLkAPILEVRCGHLVARLHTEKFVCpGIHQPCIE---LDG--ELiSPKEFTIRANKDKQKDWKGSIRI------------ 78 
O17208        64 IKlPKYMELKCGALVARLHTELFICpGIREKCIEvldCPG--ELlTPVEFTIKAEKSKQKDWKGAIKH------------ 129 Caenorhabditis ...
5_pfamImport   1 QSmPKLVEITCGALSGILHMEHFICpGIREKCISshdNPG--ELmTPVEFTIKADKIRQKDWKGAIKH------------ 66 
XP_002950533 344 RElDGALPVVCKDHTGLFMLRYMLVaCDCDDCRTqpgSGKriCW-TPIGFEEHAGMGSSKKWKKSIRLlrfrcgsaaeal 422
XP_015215125 131 SYhKIVVPVECGHKRGLFYADKLQE-G--EPCIF---AGG--RWlSPPQFEVLGGKGKAKSWKRSIFC------------ 190
1UFN_A        74 -------NGETLRHLEQKGLL 87  house mouse
EEN59154      61 -------NGTMIRRMMETGEL 74 
Q18624       133 -------ENVSLRTLLENKTI 146 Caenorhabditis elegans
CAP28875     154 -------GRSSLRTHMEALTI 167
NP_001317728 141 -------GKSNLRTLMEMRSL 154
EFO27974      79 -------GKSNMRALMEMKSL 92 
O17208       130 -------NGRMLRTLMEFKQL 143 Caenorhabditis elegans
5_pfamImport  67 -------QGRMLRTLMEFKQL 80 
XP_002950533 423 pasgsrgGCQTLGEWLERHGL 443
XP_015215125 191 -------RRVPLGELLQgdpp 204
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