2C5S,4KR6


Conserved Protein Domain Family
ThiI

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COG0301: ThiI 
Adenylyl- and sulfurtransferase ThiI (thiamine and tRNA 4-thiouridine biosynthesis) [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
Adenylyl- and sulfurtransferase ThiI (thiamine and tRNA 4-thiouridine biosynthesis) is part of the Pathway/BioSystem: Thiamine biosynthesis
Statistics
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PSSM-Id: 440070
Aligned: 330 rows
Threshold Bit Score: 248.079
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2C5S_A        14 EyILVRYGEMTTKGKN-RSKFVSTLKDNVKFKLKkf-pnIKIDATHDRMYIqlngedHEAVSERLKDVFGIHKFNLAMKV 91 
WP_011171298   2 KkFIVRYGEIGTKSRQtMHRFEKLLAKNISKLAKkhgisAEVEIIHTRLIVdvpeenFEKMKELLKKVPGIVSFSPCYYI 81 
WP_011405777   2 E-YFVRYGEIGIKSPKiRHKFEKRLMDNIKSELE-----CEFENNQGRLTLkte-etNEKVADVLSRVFGIVSYSPITQT 74 
WP_011447145   1 ---MVRFGEIFLKSEPvRREFLNRLRDNIRAGLKglnveATITITRSRILVss--esPVDLVPMLSRIFGVIDIAPVTVC 75 
WP_011832744   5 RaVMVRIGELWLKSEPvKKQFMLALTRNIKAALDtqeipYMLEEYRGRLLIfg---dAARIAPVVARIFGIVDVSICETT 81 
WP_048812380   4 DlIIARYGEVALKSNRvRRRFESRLVNNIKASID-----AEVKVNQARIYIfp--keFDDAIEKLERIFGIVSYSPAIST 76 
WP_013644859   5 RpIIVRYGEIGVKSPVvRKRFEKKLISNIKVLID-----CKININQGRIFLfp--enFEEALKSLKKIFGIVSYSPTLKT 77 
WP_007314168   8 PaVMLRYGEVFLKSDPvRREFTNTLVRNCREALRseglsPAERITRGRIFFcg--epAGRVAAVLSRIFGVVDVAECTLT 85 
WP_015285981  12 TlVMARYGELFLKSEPvKRHFIGMLLRNIRKTVGaagieCRYETPRGRILIyg--gePEKVAGIVSRVFGIIDVSTCHRT 89 
WP_074175218   2 EaVMVRYGEIFLKSEPvKRRFISIMTQTIRLALEaeglsHRIEAPRGRILIfg--dePQRIAKIAARTFGVVSVSVCTMT 79 
2C5S_A        92 PSELEDIKKGALAAFLQVKg------dVKTFKITVHRSYKHfPMRTMELLPEIGGHILENTeDITVDVHNPDVNVRVEIR 165
WP_011171298  82 DPDIEQIKKISSELFEKEIerye-nkeNITFRVKTQRPQKKfPLTSLEVNMEVGGPISEKY-GIKVDLKNPTISLDIEVF 159
WP_011405777  75 ITDKEKISELIHEIIPKVIdegkfnpqKDTFAVKCRRVGNH-DFSSQEMAGYCGSVVIDIT-NAKVDLSNPDFTLYVEIR 152
WP_011447145  76 GNSMDDLCDTAIQVAQSHLm------pHTRFAVRARREGVE-GFSSQELAAEAGSRIIDAIpDLKVDLTAPEYEIFIEAR 148
WP_011832744  82 TNRPEDMAKTALTFSEKKLk------sGMRFAVRARRQHVS-GFTSQQLAGMIADAIWEKIpDFVVDLDDPEYEIFVEAR 154
WP_048812380  77 KSTFEDIEKTVGEYAEHLYeegl-ldeNTKFAISCRRVGQH-EFSSQEMAAFAGAVVVRKY-SCPVDLSNPELTIYLEVR 153
WP_013644859  78 KTDHDTIKLAVQSYIKELVekge-fdpEKTFAVKCRRVGEH-KFSSREMAGFCGAAVIETT-HAPVDLSNPDFTLYIEVR 154
WP_007314168  86 PPDPGAVTEAAVARARASAg------pAKTFAVRARREGd-fGMTSRELAARVGSAVLAACpGITVDLDNPDYELHVELR 158
WP_015285981  90 SADLEDLKEAALSRAKKHLs------aGMSFAVRAKRQYKT-GLTSQELGTEIGSFIYDNIpGLSVDLDDPDYEVFVEVR 162
WP_074175218  80 SADIPGISAAAVEHAERRLr------pGMSFAVRARRSGVE-GFNSQELAAAVGSAVLDRIpEATVNLTAPDYEIFVEAR 152
2C5S_A       166 SGYSYIMCDERMGAGGLPVGVGGKVMVLLSGGIDSPVAAYLTMKRGVSVEAVHFHSPPFTSerAKQKVIDLAQELTKYCk 245
WP_011171298 160 NEYAYVFAKRIEGIGGIPVGTQGKVIVLLSDGIDSPVSAYMMAKRGCKLLLLHMKTSd----eGLEKTQKLVDVLSDFDp 235
WP_011405777 153 ENKTYMFTEKIPGLGGLPVGSQGSVVCLISSGIDSPVASFQMLKRGCKIILLHCDNNPYTk-nTIEKVKKQAQRLQRYSv 231
WP_011447145 149 KDGSMVYDTRISGPGGLPYGTQGKAVALISAGIDSPVAAWLMMRRGVRMIFLHIEPGKFGGedIRRNLENNLAALSHWVp 228
WP_011832744 155 EYGGIVYDERIPGQGGLPLGTAGRAVALLSAGIDSPVAAWLMMRRGVVISGVFMDGGRWAGsaTRDLAMDNVRILSTWCp 234
WP_048812380 154 DGDAYVYHEKIEGPGGLPLGTQGKVVSLVSSGIDSPVATYLMMKRGCQVIALYCDNEPYTSpeALQNFNDLIDQLNLYAs 233
WP_013644859 155 DDDTYIFHKKIKGAGGLPIGTQGRMISLVSGGIDSPVATYLMMKRGVDITIVNFNNHPFTSg-SNEKIVKIYHKLKEYAs 233
WP_007314168 159 QTGGVVYDRRIPAPGGLPLGTQGRVLALLSPGIDSPVAAWLMMKRGCEIVALHVSHGDGEDpsTLPGTLRNLAILSGWCr 238
WP_015285981 163 DFGGLVYDKRIAGPGGLPWGTQGRVLVLLSAGIDSPVASWLSMKRGCEITHLYLDAGRWAGtdVTAAAIENHRRLSLWCs 242
WP_074175218 153 EFGGLVYDEKISGPGGLPYGTQGEVMALLSDGIDSPVASWLMMRRGCLMVHVHMHSGRFGGadTEKNVLQSHARLSAWVp 232
2C5S_A       246 --RVTLHLVPFTEVQ----KTINKEI-PSSYSMTVMRRMMMRITERIAEERNALAITTGESLGQVASQTLDSMHTINEVT 318
WP_011171298 236 --EAKFVYVDFNEELakikAELTEIN-RDKYTCLYCKKYMLKLAEKHAKWHKCDAIVNGDNMGQVASQTLKNLRVISEGI 312
WP_011405777 232 gvKVKLYTINFGQYL----EHVIKQA-PPRMTCVLCKSGMYQTAAQLAKFNHANAIADGSSIGQVASQTLRNIEATRYKC 306
WP_011447145 229 glELPVITIPAEPFY----QALMTLS-EPKLRCVLCKRGMLELASRYAQKSGCDGIITGDNLGQVATQTLHNLAPISAGI 303
WP_011832744 235 grGLPLWIVNLEPFF----DAMMTAC-DRHYTCLFCKRFMMRVAEEVAKENKMEGIVSGENLGQVASQTLQNMGVITESV 309
WP_048812380 234 gaPIKRRVVKYGEYL----STCKAEA-PDKMTCVLCKSGMYKLAGKLAKKLNAEAVIDGSSLGQVASQTLPNILATREDL 308
WP_013644859 234 gsDFRLLQVDYGEFL----KKCTEEA-PPRMTCVLCKSGMYQIAEKIAKQEKALAIIDGSSVGQVASQTLPNILATRYST 308
WP_007314168 239 gfPLRLFVADAGPFY----EKLAGLH-NQRFTCVLCKRFMLRLGTLLARREGIAALCTGDNLGQVASQTLANMVVISNAA 313
WP_015285981 243 gnPVPLVIADSEPLF----DAMSRQKvQPRYRCVICKRFMLRAAARLMAHEGALAVVTGENLGQVASQTLANLGVVAEAA 318
WP_074175218 233 ghPLDLLVVDMEPFF----EAITAFR-EPRYRCILCKRFMLRVASILAEERGAYALVNGDNLGQVASQTLANMAVIAPAS 307
2C5S_A       319 NYPVIRPLITMDKLEIIKIAEEIGTYDISIRpYEDCCtvFTPASPATKPKREKANRFEAKY-DFTPL--IDEAVANKET 394
WP_011171298 313 DYPILRPLIGLDKVEIMDIARKIGTFDISTSkEVSCF--AVPKHPITNATPDEMEKIEEQLlNLRNCktCKNC------ 383
WP_011405777 307 RMPIFSPLISLDKIEIEAIAKTIGTYETSIIpDGGCS--AVPKYPETNAELDVVNNVIDDI-NQKDV--LEEVWNTFTK 380
WP_011447145 304 EIPIYRPLIGYDKEEIITLARKIGSFSSEp--GDTSCs-VLPPRPVTRSDVHQIERLMEQA-SLGSV--IEDILKFSSI 376
WP_011832744 310 KLPVLRPLLTYDKEEIVAISRRIGTYHESp--GDTGCl-AVPKKPATRSAQDLIDTEENKL-EMNEL--VRQAVESAEL 382
WP_048812380 309 DVPVLSPLIGLDKLEITRIAEKIGTFEISKRdDGGCK--AVPRYPETNADLEFVKQVKEEM-NQDEE--LEKAFKTIvy 382
WP_013644859 309 SMPVLSPLIGLDKLEISEIAEKIGTFQYSILpDSGCE--AAPKHPETNAVLEKVLEVQEEI-EMDSE--VEKVLSTLHK 382
WP_007314168 314 GIPVFRPLITFDKQEIVTLARKIGTFDERp--GDLSCp-FVPGVPATTSREDEIRTLEESL-GTDAL--LPGILGNALE 386
WP_015285981 319 TVPVLRPLITYDKEETIIVARRIGTFDAKp--GDLACr-AVPKMPATSAVLEEVKEIEQRM-EIEDL--AAAACDGLRF 391
WP_074175218 308 SVPVLRPLIGFDKEEVIERARAIGTFEPHp--GSVGCt-VAPRHPSTAAPAATIARIEEEL-DVGDL--AARAAGTVRR 380
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