pfam01051: Rep_3 (this model, PSSM-Id:395835 is obsolete and has been replaced by 460042)
Initiator Replication protein
This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.