Conserved Protein Domain Family
RobA_TF
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NF012228: RobA_TF (this model, PSSM-Id:411092 is obsolete and has been replaced by 467958)
MDR efflux pump AcrAB transcriptional activator RobA
The original characterization of RobA as a Right side Origin of replication Binding protein A (robA) may be misleading. Characterizations in large numbers of papers since then treat RobA as a transcriptional activator of the AcrAB antibiotic efflux pump.
Links
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Statistics
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PSSM-Id: 411092
Aligned: 41 rows
Threshold Bit Score: 484.02
Created: 19-Oct-2021
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_004245228   3 QTNIIRDLLAWLDNNLDQPLSLDNVATKAGYSKWHLQRMFKEVTGQAIGSYIRSRRLSRAAVALRLTSRPILDIALQYRF 82  Proteus
WP_054477345   3 QTNIIRDLLRWLDNHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGQAIGSYIRARRLSRAAVALRLTSRPILDIALQYRF 82  Photorhabdus he...
WP_038269676   3 QTNIIRDLLHWLDNNLDRPLSLDNVAAKAGYSKWHLQRMFKDVTGQAIGSYIRARRLSKAAVALRVTGRPILDIALQYRF 82  Xenorhabdus cab...
WP_045959368   3 QTNIIRDLLRWVDNNLDRPLSLDHVAAKAGYSKWHLQRMFKEVTGQAIGSYIRARRLSRAAVALRLTSRPILDIALQYRF 82  Xenorhabdus poi...
WP_036950263   3 QTNIIRDLLRWIDDNLDKPLSLDNVAARAGYSKWHLQRMFKDVTDQAIGAYIRARRLSRAAVALRLTSRPILDIALQYRF 82  Providencia alc...
WP_026822482   3 QNNIIRDLLYWIDTHLDQPLFLDNVAAKAGYSKWHLQRMFKNITQQAIGSYIRARRLSRAAVALRLTSRPILDIALQYRF 82  son-killer infe...
WP_024495215   3 QMSIISDLIKWIEKNLEQPLSIDHVAKKSGYSKWHLQRMFKDVTGKVLGTYIRHRRLTHAALALKLTSKPILDIAMQYQF 82  Candidatus Schm...
WP_039106247   3 QINIISDLIKWIEKNLEQPLSIDAVAEKSGYSKWHLQRMFKKVTGQILGTYIRHRRLTHAALALRLTSKPILDIAMQYRF 82  Frischella perrara
WP_065565969   3 QVSIISDLIVWIEKNLEQPLSIDNVAQKSGYSKWHLQRMFKEVTGQVLGTYIRHRRLTYAALSLRMTSKPILDIAMQYRF 82  Gilliamella api...
WP_065634442   3 QVSIISDLIVWIEKNLEQPLSIDNVSQKSGYSKWHLQRMFKEVTGQVLGTYIRHRRLTYAALSLRMTSKPILDIAMQYRF 82  Gilliamella api...

WP_004245228  83 DSQQTFTRAFKKQFDRTPALYRRSDEWCAVGICPPIKLDP--QPLPKWAYVQLPEIKLIGIEQTCSHTLEQWANACSDMR 160 Proteus
WP_054477345  83 DSQQTFTRAFKKQFNKTPAFYRLSEEWCATGICPPILLDK--RHIPEATYITLEELQLVGIEQSCSYMLEQWSSFCTEMR 160 Photorhabdus he...
WP_038269676  83 DSQQTFTRAFKKQFNRTPASYRRSEEWCATGICPPIMLNN--KPLPEHKFVTLEDKLLIGTEHTCSYTLEQWSKACTEMR 160 Xenorhabdus cab...
WP_045959368  83 DSQQTFTRAFKKQFDRTPASYRRSEEWCAGGICPPILLDN--KPLPAHKFVTLEEKPLIGTEHTCSYTLEQWSDACKTMR 160 Xenorhabdus poi...
WP_036950263  83 DSQQTFTRAFKKQFNLTPAFYRRTEEWCATGICPPIVLDE--HSPLDYEFVTMVEQPLIGLEQSCSYVLEEWSTACSQMR 160 Providencia alc...
WP_026822482  83 DSQQTFTRAFKKQFGITPALYRRSEDWCATGMQPPITLEE--QKLPNVSFVTLTPKHLMGIEQTCSYILEEWSTACAEMR 160 son-killer infe...
WP_024495215  83 DSQQTFTRSFKKQFKLTPANYRRAELWDPVGLTPPIQLDRklVHLPQPLFITIPEQVFWGVSYKSRCNLDNMWREQLTNR 162 Candidatus Schm...
WP_039106247  83 DSQQTFTRSFKRQFNVTPATYRRNDLWNPAGLTPPIELQKiqISLPEPTFANFPEQEFWGITYKNNCDLNTLINKNTELR 162 Frischella perrara
WP_065565969  83 DSQQTFTRSFKKQFNETPASYRRAEFWDPTGLTPAIDLHKnhLALPEPTFVDMPKQRFWGITYKNNCNLSRLLDEENNLR 162 Gilliamella api...
WP_065634442  83 DSQQTFTRSFKKQFNETPASYRRSEYWDPTGLTPAIELNKtrLSLPEPTFVTMPKQTFWGITYKNNCNLSKLLDEEIKLR 162 Gilliamella api...

WP_004245228 161 QTFWQNYIT---KVN-TIPHEVYGLHHTQHS--DEHEDEQRVIYTTAVEPAYASFV-EDDTAyEVILEAGDYIRFDFEGE 233 Proteus
WP_054477345 161 HNFWTYYLQ---NAE-VLPPVLYGLHHAIPN--PEKEDEQTVFYTTAVEPKYAQFD-VVGSQ-PVTLPAGEYVSFSYYGT 232 Photorhabdus he...
WP_038269676 161 NNFWVFYLQ---HAE-ILPPKLYGLYHSTIS--TDHEDEQTVFYTTAIEPEYATFD-TKDSQ-PVVLPGGEYISFSYFGK 232 Xenorhabdus cab...
WP_045959368 161 HDFWINYLQ---DAE-VLPPRLYGLHHATLS--TEREDEQMVLYTTAIEPEYATFD-TQDSR-PVVLPGGDYISFSYFGE 232 Xenorhabdus poi...
WP_036950263 161 QSFWRYYLE---HTT-KVASEVFGLHHAIHS--AEKDDEQTVFYTTAVKPEDASFS-NTEYS-HVTIPAGEYVKFNYRGE 232 Providencia alc...
WP_026822482 161 KHFWQYYQD---KAK-NIPNEVYGLHRVVHS--SEKDEEQTVLYITAVEPQYADNK--NNLYhSIIIEGGDYARFTFEGK 232 son-killer infe...
WP_024495215 163 EKFFVDYLNkyiKHNePIPSKLFAFFQSIES--SDNPEEQEILYTIGLEQKKNIEGiD-----QFSHKAGLYASFKYVGP 235 Candidatus Schm...
WP_039106247 163 KQFFNDYLAktfNNKrTLPDKIYSFSRLVKSkdKDNQDEQELLYSIAIEEQNISENtK-----KIVSSGGLYLCFKYVGS 237 Frischella perrara
WP_065565969 163 VQFFHNYLSrysNKKeQLPDKIYAFSRILKS--NDNANEQELLYTIALDHNNDLEYiE-----EITSEGGLYLCFKYIGS 235 Gilliamella api...
WP_065634442 163 VQFFHNYLTryaNKNeALPERIYAFNRILKS--KDNANEQELFYTIALEHNNNLEHiE-----QFVSEGGLYLCFKYFGP 235 Gilliamella api...

WP_004245228 234 akRGAMQEFLFLIYGVCLPTMGLTRRKGHDIEKYYLKEVHYDnvmtaEPQDHIkRFEYYIPIK 296 Proteus
WP_054477345 233 --KEGLQNFLFTVYGICLPILNLTRRKGYDIERYYPTHINDRd---kEAKNHIiEFQYLIPIQ 290 Photorhabdus heterorhabditis
WP_038269676 233 --EDHLDEFLFNIYTVCLPQLNITRRKGYDVERYYLTNLERKkl-edESQSHVvEFEYLIPIQ 292 Xenorhabdus cabanillasii
WP_045959368 233 --KEQLQEFLFTIYGICLPTLNITRRKGYDVERYYLTNLEWKnl-gdESQNHVvEFEYLIPIE 292 Xenorhabdus poinarii
WP_036950263 233 ttRERMQEFLYHVYGVYLPKLNLTRRPGYDVEHYKIKDVTHNeitdtDPRTHIeAFSYYVPIK 295 Providencia alcalifaciens
WP_026822482 233 ptKSDLQQFLYMIYGVYMPNLNLTRRAGHDIEHYHLKDPNNPecnydNPENHMvAFDYFVPIK 295 son-killer infecting Nasonia vit...
WP_024495215 236 --IDDFWDFIIQVYLAAMPSLGVKLRRGPHIEIYH-HNSNWDlkrlqRPKLI--ECDYCIPVV 293 Candidatus Schmidhempelia bombi
WP_039106247 238 --PASFIDFMNHVYFSAIPRLNVQLRRAEVIEIYRNHDNVSRlgnitEINVL--DCDYCIPIV 296 Frischella perrara
WP_065565969 236 --LDNFKDFISQVHLAAMPALKVRLRIGSIIEIHYNRHDETVes-vkDVQCM--ECDYCVPVV 293 Gilliamella apicola
WP_065634442 236 --PENFKDFISQVHLAAMPALKVRLRSGCLIEIHHNLHDDSVks-vkNLQRI--ECDYCVPVI 293 Gilliamella apicola
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