16127055 37 VAvkkRLADAALTAAKAAGASYCDVRVGRYLRQFILTREA--NVQGVTNTESSGVGVRVIANGAWG--FAATNNMSPe-S 111 Caulobacter crescen... 16127056 3 IMteaEAKTILDKVLKLSTADECTAQLTGSIEGNIRFALN--NVSTSGVVSDTNLGVSVAFGRRVG--TASTNDFSDa-S 77 Caulobacter crescen... 15841819 2 IEpqhAVNIVLKEAARSGRADETMVLVTEKVEATLRWAGN--SMTTNGVSHSRNVTVISIVRRGDSa-FVGSVVSA---E 75 Mycobacterium tuber... 15597726 1 -MhqrQHFEALAEDLRRHLAEGEDFTLWYSAEDSEFIRFNraRVRQAGRVRQASALLRLIRDERQAs-LDLTLSGAPe-E 77 Pseudomonas aerugin... 14521457 1 MVemfDVNELILKKAKELGFGDVVVLSYETNRRQIRFANN--EVTVAKHWNERKVELFVEW--EKRiaGTSITDLTEenI 76 Pyrococcus abyssi 18313687 1 ----------MIFKLLAGRADEAAVVKIKQLNYMIRFAND--DITVFKNWQSENTFIYLSKARKTA--FVGVTGPP---T 63 Pyrobaculum aerophilum 14590710 1 MMemfEVNELILKKAKELGLGDVVVLSYETDRRQVRFANN--EVTVAKHWHERKVELFVEW--KKRiaGTSITDLSEenI 76 Pyrococcus horikoshii 15609451 2 IEpqhAVNIVLKEAARSGRADETMVLVTEKVEATLRWAGN--SMTTNGVSHSRNVTVISIVRRGDSa-FVGSVVSA---E 75 Mycobacterium tuber... 13541630 1 MIemaDVEHLIRKLSDN--FEEYVVKQEYASDTQVRFSNS--KLDLTNIWDEYGIDIFVSS--GRKtaSIAVHSPDE--G 72 Thermoplasma volcanium 16081872 1 -MnmfDMDRISESFEKR--FDEYAIEMHVNRDDQVRFSNG--SRDLHNIWEESVLLVFVAR--GKRtlMTTIKEGAD--L 71 Thermoplasma acidop...
16127055 112 VAQTARLAVAIAKANskNQTAPVQLAPTKGVGEVKWATPIRRNGMEVSLQEKVDLLMRVNGAALKAGAN---FVNSSLFL 188 Caulobacter crescen... 16127056 78 LARAVKRAEELARLAp----ENPEFVPAVEKQVYKPSSTFSAATAAITPEQRAEIAMASIAPCRAKNl----IAAGFLND 149 Caulobacter crescen... 15841819 76 VDPSVLPGLVVSS------QDAARSAPEAGDAAPLLADTGEPDDWDAPVPGTGAGVFTGIAGSLSRGFRgadRLYGYAHR 149 Mycobacterium tuber... 15597726 78 DRQRLAEGLRQLR-------QSLAWIPADPYLLLDTSAWQRENQDLGAAPDSGALLASLERRARDLD------LVGIYAA 144 Pseudomonas aerugin... 14521457 77 ERTLKTLKANLEKMK--PREDYYGIAEGPFKYEDIPETFDKAIVELDDPSEYVERAINAALEEGA--K----RVAGVLYT 148 Pyrococcus abyssi 18313687 64 VEKIEEAVKSLASLP-----------EDPLYIPLGGPQPAKYHEPPEDFSKLPDLVKTAVDSAQGVER-----SAGVVHL 127 Pyrobaculum aerophilum 14590710 77 ERTLKTLKANLEKMK--PKEDYYGIAEGPFEYKDIPETFDKAIIELDDPSEYVETAINAALEEGA--K----RVAGVLYT 148 Pyrococcus horikoshii 15609451 76 VDPSVLPGLVVSS------QDAARSAPEAGDAAPLLADTGEPDDWDAPVPGTGAGVFTGIAGSLSRGFRgadRLYGYAHR 149 Mycobacterium tuber... 13541630 73 ISKIDYLQKVLSNS---PENSIY---EGINDKKQIYRAVDYKDDEKD-VQDMAVAAISSAEDEGA--R----RVSGLIYK 139 Thermoplasma volcanium 16081872 72 ERSIEDLSRRIDQT---PENPLF---SGINDRKQVYRKLDLPPREFD-ADELADMAMAGSRDAGS--E----RMAGLVYS 138 Thermoplasma acidop...
16127055 189 INEQKYFASSDGSFIDQDVHRVWAPFTVTAIDKASGKFRSREGLSAPmgmGYEYLDPKaedkvlspngiisynksydMVE 268 Caulobacter crescen... 16127056 150 EQSFVAFANSKGAFGYQRSTDMDYTCTVRTADGRGSGWVARSLQDST------SFKP---------------------AS 202 Caulobacter crescen... 15841819 150 SVSTTFLASSTGLRRRYTQPTGAIEINAKRG--D---ASAWVGIGTP---DFVEVP---------------------IDL 200 Mycobacterium tuber... 15597726 145 GPLFRGFANSWGAFGWHAGSSFNFDWSLFHG---NGQAVKADYAGQR------WDDEA-------------------FAR 196 Pseudomonas aerugin... 14521457 149 DHDKIYLTTSNGVEAFDEGTGIEISVRAFIG--DL---ESGHGTNSV---RVLKKFD--------------------PES 200 Pyrococcus abyssi 18313687 128 AYVTVTYEDTAGREGSYSVNRIYMTMRSFLGELSATSAAAGRRIGDI------KAER--------------------LGE 181 Pyrobaculum aerophilum 14590710 149 DHDKIYLTTSNDVEAFDEGTGIEISVRAFIG--DL---ESGHGTNSV---RVLKKFD--------------------PES 200 Pyrococcus horikoshii 15609451 150 SVSTTFLASSTGLRRRYTQPTGAIEINAKRG--D---ASAWVGIGTP---DFVEVP---------------------IDL 200 Mycobacterium tuber... 13541630 140 RSSEESIFTRYNTYSAHK-YGIEAAVRSFIG--E----SSGQYTAHY---GPSSKAD--------------------TEE 189 Thermoplasma volcanium 16081872 139 MRSRVEIATRYNRGSYDS-IGAEVVVRSFRG--D----RSGQECGHT---GINGYLD--------------------AYA 188 Thermoplasma acidop...
16127055 269 DAQAAAVQAREKLTAK-SVKPGR-YDLVLDPNHLGLTIHESIGHPLELDRVLGYEANF-AGTSFATldkreqrfQYGNEI 345 Caulobacter crescen... 16127056 203 DIEIAMRKASASAEAQ-ALEPGK-YTVILEPAAASGLIS-FMFNFFDARQADEGRSFLsKKGGGNKlg-----eQVYDPR 274 Caulobacter crescen... 15841819 201 MLERLSTRLRWAQRTV-ELPAGR-YQTIMPPSTVADMMI-YLGWSMAGRGAQEGRTAF-SAPGGGTrv----geRLTELP 272 Mycobacterium tuber... 15597726 197 RFEQAREQLGHLGKPLrQLRPGD-YRAYLAPAALEEVMQMLCWGGFSARALATGESPL-QRLQNGD--------ALLSPL 266 Pseudomonas aerugin... 14521457 201 AG-RKAGEIAKMARNP-EQGPEGkFDVIFDPLAFANLLS-YMGWAFSAFAVEAGFSY--FANKLDQ--------KVASEV 267 Pyrococcus abyssi 18313687 182 ENSHILRLAKGLPQTR-AEPSRT--SLLLTPLVFGHIISEIAAVWASGSEILAGSSRY-TKDDLGR--------EVASPL 249 Pyrobaculum aerophilum 14590710 201 AG-RKAGEIAKLARNP-EQGPEGrFDVIFDPLAFANLLS-YMGWAFSAFAVEAGFSY--FANKLDQ--------KVASEI 267 Pyrococcus horikoshii 15609451 201 MLERLSTRLRWAQRTV-ELPAGR-YQTIMPPSTVADMMI-YLGWSMAGRGAQEGRTAF-SAPGGGTrv----geRLTELP 272 Mycobacterium tuber... 13541630 190 VGKRSVRSILKVDS---VKGNEGkYRVIFSPMAFGNIIS-YGSYLFSAYSIISGMSY--LEGRIGK--------EVANES 255 Thermoplasma volcanium 16081872 189 IGKRSAESIVNAER---HEGREGhYDVILAPMAAGNIIT-SGSYAFSAHTVISGLSF--LQDSMGR--------QIAAPM 254 Thermoplasma acidop...
16127055 346 VNVFADKVQPGSLGAVGFDDEGIKTKSWPLIQGGKLVDYQTTRDQAHILGKTEsDGCSYADSWSTVQFQRMPNVSLEPGk 425 Caulobacter crescen... 16127056 275 VTFMSDPWHP-ELAVLPWDATGRAREKMAMVENGKIANLIYTPYWAQKQGKPV-------VG-------RPGNIIMSGG- 338 Caulobacter crescen... 15841819 273 LTLFTDPAAP-GLACTPFVAVSNSSETQSVFDNGMEISQVDWIRSGVINALAYpRATAAKFD---APVAVAADNLIMTGg 348 Mycobacterium tuber... 15597726 267 LNLAERPATSP---SPAFSAEGSPRAEVELVGNGRLSGRLVSSRSAREYGLVA-NGAG--------ANEAPTALDMAGG- 333 Pseudomonas aerugin... 14521457 268 VTIKDIGNLPNGYGTRKFDDEGVPTRETVLIERGTLKTYLFNTSLAKKYGKET-TANA--GL----ISPRAWNIVLEPGd 340 Pyrococcus abyssi 18313687 250 LTVIDITHSQEAFGYTPFDMEGLTPRPVDVYKKGVLAGFLHTRRTAHALGMEP-TGHALYNWTRPTPG----HVYIAPGd 324 Pyrobaculum aerophilum 14590710 268 VTIKDVGNLPNGYATRKFDDEGVPTKETILIHKGILKTYLFNTSLAKKYGRET-TANA--GL----IAPRAWNIVLEPGd 340 Pyrococcus horikoshii 15609451 273 LTLFTDPAAP-GLACTPFVAVSNSSETQSVFDNGMEISQVDWIRSGVINALAYpRATAAKFD---APVAVAADNLIMTGg 348 Mycobacterium tuber... 13541630 256 FSLVDDPTDTKGIGFEYFDDEATATKRNTIIERGILKTYLHSYSTAKKMHTET-TGNA--GI----ISPEAWQLEVDGGd 328 Thermoplasma volcanium 16081872 255 VNLYDDPTDTAGMAYRVFDEEGTATSRVPIIEHGVLNTYLHSTSTARYMNTET-TGNA--GI----ISPEAWQLEMDGGd 327 Thermoplasma acidop...
16127055 426 kPLSLADMIGNVENGIYILGRGS--FSIDQQRYNAQFGGTLFYEIKDGKITQPLEDVAYQMRTPEFWNACSAICDERDYR 503 Caulobacter crescen... 16127056 339 -TKSTADLVRETERGILVTRTWYirMVDPQTVLLTGLTRDGTFYIENGQLKYPLKNFRFNESPVIMLNNIDELGRPVRVG 417 Caulobacter crescen... 15841819 349 -SADLADMIAGTERGLLLTTLWYirEVDPTTLLLTGLTRDGVYLVEDGEVSAAVNNFRFNESPLDLLRRATEAGVSEPTL 427 Mycobacterium tuber... 15597726 334 -SLEQARILEALDTGLYIGNLWYlnYSDMPAARLTGMTRFATFWVENGQIRAPVSTMRFDDSLYSFLGAHLEDLSHEREL 412 Pseudomonas aerugin... 14521457 341 --YTKDELFQEVKRGIYITNVWYtrFQNYMTGDFSTIPRDGIFLIENGELKPIRN-IRVSDNMLRILQNIVGLTKESHHV 417 Pyrococcus abyssi 18313687 325 gGTDVEDLFRELKNGVYIHNNWYtrFQNVKTGQFSTVGRDVALEVKNGKPAAVIKYIRIADTLENVAKNVALLSKETKQV 404 Pyrobaculum aerophilum 14590710 341 --YTKDELFQEVKKGIYITNVWYtrFQNYMTGDFSTIPRDGIFLIENGELKPIRN-IRVSDNMLRILQNVVALSKESYHV 417 Pyrococcus horikoshii 15609451 349 -SADLADMIAGTERGLLLTTLWYirEVDPTTLLLTGLTRDGVYLVEDGEVSAAVNNFRFNESPLDLLRRATEAGVSEPTL 427 Mycobacterium tuber... 13541630 329 --SSLDEMIADTKEGVVIMNSWYlrFQDYRNGVFSTVPRDGIYHIVKGEIKESWSGIRISDSYSNVLSNISLISKEAEYV 406 Thermoplasma volcanium 16081872 328 --ASAEELISDTREGVFIRNSWYlrFQDYRNGVFSTVPRDGVYYIRNGEIAEAWDGIRISDSIPEILKKISALSKETQYV 405 Thermoplasma acidop...
16127055 504 LFGsFFDGKgqpsqvsavsHGSSTTRFDGI--NVINT 538 Caulobacter crescentus CB15 16127056 418 EGMpMMIP--------------PMRVRDFTftSLSDA 440 Caulobacter crescentus CB15 15841819 428 PREwSDWVTr---------TAMPPLRIPDF--HMSSV 453 Mycobacterium tuberculosis CDC1551 15597726 413 RLSsNTYGErqt-----dsMHLPGALTGRF--TLTL- 441 Pseudomonas aeruginosa PA01 14521457 418 HWWeVSRPV-----------TTPYVLVKEV--GITRA 441 Pyrococcus abyssi 18313687 405 YWWdMPTP-----------THSPYAILNNIg-ITT-- 427 Pyrobaculum aerophilum 14590710 418 HWWeVSRPV-----------TTPYVLVKEV--GITRA 441 Pyrococcus horikoshii 15609451 428 PREwSDWVTr---------TAMPPLRIPDF--HMSSV 453 Mycobacterium tuberculosis H37Rv 13541630 407 KWWnEISAS-----------KMPYIAIDKV--TLTRS 430 Thermoplasma volcanium 16081872 406 KWWnEVMPS-----------RLPYIKVSGL--GLTKS 429 Thermoplasma acidophilum
Jiyao W et al.(2023). "The conserved domain database in 2023.",