16263454 35 KPMSADLILHHGLVTTLDR----TNPNATAIAIRDSKFLAVGDDRDIMALAG-PETKVIDLKGKRVLPGLIDNHTHVVRG 109 Sinorhizobium meliloti 15615762 1 ----MGTLWWNGTFFTMVH----EGDQVEAVFTEDGKIVAIGTAEELRQRYStRINQEMNCDGAYVYPGFVDSHLHMIGH 72 Bacillus halodurans 16080007 1 ----MKAIWHGGFIYTMLE----EGDRTEAVYVEDGVIKGTGSYERLKEKYGsPETEEISLNGAVMFPGFVDSHLHLIGH 72 Bacillus subtilis 19703984 1 ---MLDKLFINGEIYSMKK----EGEKFQSLGVKDGKIVFLGTNDEAKNv---SSKELIDLKGKMMIPGMADAHLHLYAY 70 Fusobacterium nucle... 15841540 1 MSQIPVKLLVNGRVYSPT------HPEATAMAVRGDVVAWLGSDDVGRDQf--PDADVQDLDGRFVAPGFVDSHIHLTAT 72 Mycobacterium tuber... 15609189 1 MSQIPVKLLVNGRVYSPT------HPEATAMAVRGDVVAWLGSDDVGRDQf--PDADVQDLDGRFVAPGFVDSHIHLTAT 72 Mycobacterium tuber... 13541745 1 ---MFDLLISNCTVFG--------REGSDAIGINEGRIAFIGID---RDl---RAKKRIDLSGKIVFPGFIDSHAHLLST 63 Thermoplasma volcanium 16082546 1 MPLVFDTLITNARIFG--------HEDADTIAIDRGRIVYVGRD---HGl---EAKNTFDLSGGYVLPGFIDSHAHLLST 66 Thermoplasma acidop... 15790774 1 MTAAADLILYNGDVHVLTDtatpADPAHSAVAIRDGRIVGLSNDYDAAFRAD-TGTREVDLGGRVVVPGFVDAHTHLAVL 79 Halobacterium sp. N... 16801510 1 -----MKLWENGTFYQMTA----EGEQVSAVLTKNGQIHAVGEVADLKKQYAtEIDETIDLEGKVVFPGFVDAHIHLLWY 71 Listeria innocua
16263454 110 GLNYnIELRWDGVRSLADAMDMLKRQVAITPPPQWVRAVGGFTEHQFVEKRLPTIDEINAVAPD-TPVFLLHLYDR-ALL 187 Sinorhizobium meliloti 15615762 73 GEKL-LRLDLSTVMNAEDMREKLMERVALTEEGDWVTAEGWN-ENNFPDQKIFHRNELDEIAPN-HPMILTRVCRHaILV 149 Bacillus halodurans 16080007 73 GEKQ-LQLDLSALTSKDSILQAAKERERQLPKNDWLIGEGWN-ENQFETPDYLTKHDLDRLFPD-RPVLLKRICRHaIAV 149 Bacillus subtilis 19703984 71 CQNL-TFVDLSKVHDINEMVSLMKEKVKNIKKGDWIKGVNFD-QSKWKENRFPTLQEMDSISKD-NPVIIKRCCLHaVVA 147 Fusobacterium nucle... 15841540 73 GLML--SGL--DLRPAISRAQCLRMVADYAADHPGQPLWGHGWDESAWPENAAPSTADLDAVLGdCPAYLARIDSHsALV 148 Mycobacterium tuber... 15609189 73 GLML--SGL--DLRPATSRAQCLRMVADYAADHPGQPLWGHGWDESAWPENAAPSTADLDAVLGdCPAYLARIDSHsALV 148 Mycobacterium tuber... 13541745 64 GLED--IRL--NLYHTKSKEEVVERIAEYSKGK--EKVIAYRWDESMWKPQSSYLTSS-DINGIpVPVVAFRRDGHmAVA 136 Thermoplasma volcanium 16082546 67 GLEQ--TRL--NLFEYEAKIEAIDAIRRYAEKH--DKVVAYRWDESRWRDDPTYITAS-DLDGIvKPVVAFRRDGHmAVA 139 Thermoplasma acidop... 15790774 80 GKHG----VHADLRGADSPAAATARLAERARETDAGWVLGFGYDDSQWSAALSTADLDAVSEAR--PVAAIREDMHtATV 153 Halobacterium sp. N... 16801510 72 GQAL-ERLNLNQTTTKKEALALILERTKQLASEEWLFVEGYDENKWSDEQTLISLVDLDGVSTT-NPILVRRIDYHsVSI 149 Listeria innocua
16263454 188 NGAALRAVGYTKDtPNPPGGEII-RDASGNPTGMLLAKpnAAILYSTLAKGPKLPFEYQVNSTRhFMRELNRLGVTGVID 266 Sinorhizobium meliloti 15615762 150 NSKALQLAGISKDtTDPPGGRIV-RDELGEPTGYLLDT--AQELVKRVAPSVSAAYLERALAA--AVDDMVAKGLVGGHT 224 Bacillus halodurans 16080007 150 NSAALQAAGISRNtPDPDGGVIV-KDANGEPTGLLFDK--AQDLILKAVPPVSQHYVDEALTA--AIKDCWTKGLTGGHS 224 Bacillus subtilis 19703984 148 NSKALEMAGIGKN-YQAGSGGIVeLDKDGMPNGILREQ--STKAFDDILPDPLKDIEVQKKIMQdVLNDMSSKGITTIHT 224 Fusobacterium nucle... 15841540 149 SSGLRRLVPELAAa-------TG----YTAQRPLTG----DAHHLARAAARYLLTDVQLADARAvALQAIAAAGVVAVHE 213 Mycobacterium tuber... 15609189 149 SSGLRRLVPELAAa-------TG----YTAQRPLTG----DAHHLARAAARYLLTDVQLADARAvALQAIAAAGVVAVHE 213 Mycobacterium tuber... 13541745 137 NQKAMDVIGTTRKe-------GI----FKED---------DIELLEPLVK---PNEAEIRDALNtAANRAISLGIVAVRD 193 Thermoplasma volcanium 16082546 140 NDQAMRSIGQHRPd-------GI----FREE---------DMQMLDPLVK---PGEEEYVQALQtAIGISASLGITGVRD 196 Thermoplasma acidop... 15790774 154 NGVALAEHGDEMP------------AADVGEDGRIVED--AV---EAVYDATDPDLAGTRPLIEaAQREANERGVTAVHE 216 Halobacterium sp. N... 16801510 150 NSALKAHIENFSEn-GFDGGGEIvRDKAGNFTGILRDN--ATTLAIDAFPAATPAELNAWLKI--AITDLWSKGITGAHS 224 Listeria innocua
16263454 267 AGGgY-QNYPDDYAVIQKLADDGQMTVRLAYNLFTQKPKEEKQDFLNWTSSVKYKQGDD--YFRHNGAGEMLVFSAADFE 343 Sinorhizobium meliloti 15615762 225 EDLgYyLGFNQTFATFQRVIDGNTRRFRAHLLVHHEVIDDMIKAGYCKGPVGEWLEFGAmkIFADGAFGGRTALLSEPYC 304 Bacillus halodurans 16080007 225 EDLsYyGDVSVPMKAYEKAAAGGKYPFRCHLLVHHEAVDRWEQLEKLSGP---YVEFGAmkIFADGALGGRTALLKEPYQ 301 Bacillus subtilis 19703984 225 YAAkI-WQYNEDISIYKNFEKEEKLPLRVTVCIDELFEPE-ILTEEKLNNPYRKVQLGAykIFSDGSMGSRSAALKAPYT 302 Fusobacterium nucle... 15841540 214 CAG-PeIGGLDDWLRLRALEHGVEVIGYWGEAVATPAQAR---DLVTETGARGLAG--D--LFVDGALGSRTAWLHEPYA 285 Mycobacterium tuber... 15609189 214 CAG-PeIGGLDDWLRLRALEHGVEVIGYWGEAVATPAQAR---DLVTETGARGLAG--D--LFVDGALGSRTAWLHEPYA 285 Mycobacterium tuber... 13541745 194 MVd---ISTYNEYKNIKTPLKIYKVL--YSDSIFDKFGT-------SSQNDWGIK------AFLDGSLGSRTA-AHKGWD 254 Thermoplasma volcanium 16082546 197 IVd---RATYDAYRRIKSNVRIFKVI--YAEDLFAGFG--------SDPSDWGVK------TFLDGSLGARTA-AHEGWD 256 Thermoplasma acidop... 15790774 217 MVR----DSHAP-RVYRELDAAGELSVRVRLNYWADHLDAVLETGLVTNHGGGMVTVGGikTYTDGSLGGRTAKLSEPYA 291 Halobacterium sp. N... 16801510 225 EDLhYfTGFESTFAAFRNTVGANRLPFRAHLLIHHAELANFSTSKESFMSGDKFLELGAmkIFYDGTVGSRTALMSAGYA 304 Listeria innocua
16263454 344 DFRQPRpDMPPEMEGDLEEVVRVLAENRWPWRMHATYDETISRALDVFEKVNQDMP---------LEGLNWFFDHAETIS 414 Sinorhizobium meliloti 15615762 305 DAPTTS-GVAIHTQEQLTNLIKKARQYKLPVAIHTIGDEALRMAITSIEAHPVTE------------GR-DRLIHTQVTP 370 Bacillus halodurans 16080007 302 DDPSTN-GVQVHDDETLGRLIRKAREKGMEVAVHAIGDLAFEKVLNAIEKHPPKN------------GRHDRLIHAQVLD 368 Bacillus subtilis 19703984 303 DDPENS-GFMLFTQEELNNKILTAYEHGLQPAIHAIGDRALDMTLAAIEYTLKTTKekgmtdeeqKKRLPFRIIHVQMID 381 Fusobacterium nucle... 15841540 286 DAPDCI-GTCHLDVDGIEAHVRACTKAEVTAGFHVIGDAAVSAAVAAFERVVADLGvv------aVARCGHRLEHVEMVT 358 Mycobacterium tuber... 15609189 286 DAPDCI-GTCHLDVDGIEAHVRACTKAEVTAGFHVIGDAAVSAAVAAFERVVADLGvv------aVARCGHRLEHVEMVT 358 Mycobacterium tuber... 13541745 255 AS------NLKMDESKFENFAKQIWMHNLPLAVHAIGEVAVETAAKVFYRNA---G-----------RNRNSIEHFELV- 313 Thermoplasma volcanium 16082546 257 TK------NLKMSEQQFERFCEGTWSRNLPVAVHAIGDLAVRVAAETMHRHA---G-----------RQRNSIEHFELV- 315 Thermoplasma acidop... 15790774 292 DAPGET-GQWVVDPSALAALVERADDAGLQVVAHAIGDAAVDAVLDAYEDAG---------------ERRHRIEHAELAS 355 Halobacterium sp. N... 16801510 305 DNPNEK-GLQIHSDEAFEDLVQSARKAGLPVAIHILGDQAFANVIRTLRANPPKE------------GQYDRLIHTPWLT 371 Listeria innocua
16263454 415 ERSIDRIAALGGGIATQHRMAYQG----EYFVERYGHGAAEATPPIAKMLEKGVHVSAGTDATRvASYNPWVSLSWMITG 490 Sinorhizobium meliloti 15615762 371 PSLVERMKKLKVILDIQPAFVPADf---PWVEERLGNERLSYSFAWKTLLRSGMALAGGSDAPI-EEVDPLYGIYAAVAR 446 Bacillus halodurans 16080007 369 NELIERAARMPIALDLQPHFVASDf---PWVIDRLGKDRMKTAFAWKTLISKGILCAGGSDAPI-EPVDPLLGIQSAVLR 444 Bacillus subtilis 19703984 382 DNLLERMKKLPLVLDIQPIFLCTDl---HWIEDRIGKERLKGSFALKTMENAGLIQTGGSDCPV-ETYEPLKGIYAAVTR 457 Fusobacterium nucle... 15841540 359 ADQAAKLGAWGVIASVQPNFDELWgggdGMYARRLGAQRGIELNPLALLASQGVPLALGSDAPV-TGFDPWASVRAAVN- 436 Mycobacterium tuber... 15609189 359 ADQAAKLGAWGVIASVQPNFDELWgggdGMYARRLGAQRGSELNPLALLASQGVPLALGSDAPV-TGFDPWASVRAAVN- 436 Mycobacterium tuber... 13541745 314 DDDVLDYITKTTIISSQPNFLE-WagkgGMYEDRVGGEWLYKNNPFRWMIDRGIHLAFGSDS---MPIGPMYGIYYAVN- 388 Thermoplasma volcanium 16082546 316 EDGVLDIIDANTIVSAQPNFLE-WaghgGMYQDRLGESWLYRNNPYRDILDKGLKLAFGSDS---MPLGPMYGIHYAVN- 390 Thermoplasma acidop... 15790774 356 DDAIERMADLGVVASVQPNFLKWAgs-gGLYADRLGTARREASNRFADMLDAGVDVAFGSDC---MPLAPLVGVHHAVTA 431 Halobacterium sp. N... 16801510 372 KELIAEAEGLPILFDVQPQFMASDl---PWAIDVLGENHPPLAFAWNSLLRAGFPLAGGSDAPI-EVPNPFWGIHAAVTR 447 Listeria innocua
16263454 491 KTLGGMQLYPRAn---CLDRETALRMWTENVTWFSNE-EGKKGRIEKGQFADLIVPDK------------DFFACPEDEI 554 Sinorhizobium meliloti 15615762 447 KKPTDQH-EGYLpe-eKLTRYEALQLYTTGSAYAIER-EHERGNIRPGYVADFTMLNR------------NLFTCREEEL 511 Bacillus halodurans 16080007 445 KSSHEQNGPSYNes-eCLPVYEAIKLYTEGSAGIIYK-EKSRGKIAEGYDADFTVLSG------------DPFAIDPAQL 510 Bacillus subtilis 19703984 458 QDMEGYPTEGFLpe-eRLSIYEALCMYTKNVHYATGQ-ESVLGTLEIGKFADLTVLEK------------DLFKIDETEI 523 Fusobacterium nucle... 15841540 437 ----------HRtpgsGVSARAAFAAATRGGWRAGGVrDGRIGTLVPGAPASYAIWDAgdfdvdaprdavQRWSTDPRSR 506 Mycobacterium tuber... 15609189 437 ----------HRtpgsGVSARAAFAAATRGGWRAGGVrDGRIGTLVPGAPASYAIWDAgdfdvdaprdavQRWSTDPRSR 506 Mycobacterium tuber... 13541745 389 ----------SEyqrqKITLEEAVRCYSEGGSYLLGT-EGYMGMLRVGYSADMAVFDE-------------KLLKDLRGI 444 Thermoplasma volcanium 16082546 391 ----------SEfsqqRITFDEAVRSYSEAGSYLIGA-ENWIGRIETGYSADFAVFNE-------------RNIEDRRRL 446 Thermoplasma acidop... 15790774 432 P----ADA--QR-----LSVTAALRAYTSGGARAGCR-EDEQGVIREGALADLTVLDAs------------PWEHADAIA 487 Halobacterium sp. N... 16801510 448 TANADLN-GVKYwpeeSLTVYEAIELYTKGAAFASYK-TTSRGQIAPGFVADFTILAE------------DPFLIKPANL 513 Listeria innocua
16263454 555 SFITSELTMVGGK-----IVYGTG 573 Sinorhizobium meliloti 15615762 512 LTTRVEKTVIGEA-----IVFQA- 529 Bacillus halodurans 16080007 511 HLLEIKKTVINGQ-----IVYEKS 529 Bacillus subtilis 19703984 524 KDVKVEQTYVAGN-----CVFMIK 542 Fusobacterium nucleatum subsp. nucleatum ATCC 25586 15841540 507 VPALPRLGPTDALprcrqTVHRGA 530 Mycobacterium tuberculosis CDC1551 15609189 507 VPALPRLGPTDALprcrqTVHRGA 530 Mycobacterium tuberculosis H37Rv 13541745 445 KAAKPEITIING------KIYTN- 461 Thermoplasma volcanium 16082546 447 KEAKPLMTIVHGN-----TIYDAS 465 Thermoplasma acidophilum 15790774 488 DEVGVSMTVVDGA-----VVYDGR 506 Halobacterium sp. NRC-1 16801510 514 RHLEVMMTVVNEQ-----VVYKKK 532 Listeria innocua
Jiyao W et al.(2023). "The conserved domain database in 2023.",