Conserved Protein Domain Family
PRK00451

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PRK00451: PRK00451 
aminomethyl-transferring glycine dehydrogenase subunit GcvPA
Statistics
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PSSM-Id: 234769
Aligned: 264 rows
Threshold Bit Score: 511.991
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
218883609   7 HPWIPGStEESLKKMLDVIGVKSITELFNDIPREVLLGEdewnrleIGVGRPL-SEIEAKEIVDEKLAKNRVFN-PPPFM 84 
111025249   7 HPYMANSvPALQQEMLDAIGVPTIAELFQQIPTDHRTTRk------FDLPPTL-GEAELRRHLVNTLAKNRTCEqNLNFL 79 
271968917   3 HPYIPNAePGVRAEMLAAIGAASVEEFYAAIPAGLRLDRp------LDLPAPMaSEHELVTHMRGLLARNTDTTeALSFL 76 
240103758   3 KHYLPNL--AHREEMLREIGFASIDELFSDVPEGMLKEF--------NLPGGK-SEYEVFIELNETLSKNKTALeMPSFL 71 
242398920   6 RHYIPNS--GHKEEMLREIGFKSIADLFSDVPEDFVKEF--------NLPEGK-SEYEVFLEMNEILNKNKSVLeMPTFL 74 
226315349   8 HPYIPNSaPEVKEKMLTEIGFSSIEDIYADIPEELRLKDk------MNIPKAL-TEYELERHVNQLMNKNQTTKeNISFL 80 
294102736   8 YPYIPNSvPHIQEEMLKEIGAESIDEFFECIPEELKLKGp------LDLPAPLlSEAGLKRHIERILSKNATISeNISFL 81 
291300223   3 HPYIPNAePQVKAEMLAATGATDIEDFYADIPEHLRLRRp------LDLPEPLrGEADLVRHVGGLLDRNTSTAeALSFL 76 
121609415   7 YPYIPNSvPQVKAAMLAATGARSIDDFYADIPAALRAPRa------MNLPAPLlSEARLKRHVQGLLARNRPCSeVLSFL 80 
256391229   3 HPYIPNSdPEIRGRMLAAIGAASVEEFYADIPDAIRLHRp------LDLPAPLrSEAELVRHMDRLLSRN--KPaELSFL 74 
218883609  85 GGGVYPHYVPPIVKYIISRGEFLTAYTPYQAEISQGLMQAIFEYQSMMAELLEMDIVNASMYDWSSSIAEAVLMAFRVRk 164
111025249  80 GAGLWQHHVPAACDEVVRRNEWLTSVFG-EPSSDHGRNQAWFEFCSQLGELLKLDLVGLPVRSWGSAAGHALRMAARIT- 157
271968917  77 GHGCYPHHVPAVCDEVNGRSEFLTAYAG-EPYEDHGRFQAMFEYVSMMAELLEMDVVNVPTYDGYQASGTAIRMAARYT- 154
240103758  72 GAGTYFHYIPAHVKYLIERSEFLTAYTPYQPEISQGMLQALFEYQSMMAELYGLPVVNSSMYDWGTSIAEAALMTVRLHr 151
242398920  75 GAGAYFHYVPAHVKYLIERSEFITSYTPYQAEISQGMLQALFEYQSLIGELVGLEIVNASMYDWGTAMAEAALMSARVT- 153
226315349  81 GAGCWPHFVPAVCDEINSRAEFVTAYAG-EPYEDKGRFQALFEYQSLVAELVDMDVVNVPTFDWAQAASTALRMAARIT- 158
294102736  82 GGGCWNHYVPAVCDEVNQRSEFLTAYAG-EPYEDHGRFQALFEYESMMAELIDMDVVNVPTYDGAQASATSIRMAARIT- 159
291300223  77 GAGCYRHYVPAVCDEVNSRSEFLTAYAG-EPYEDHGRFQAMWEYQSMMGELLEMDVVNVPTYDGFQAAATALRMAGRIT- 154
121609415  81 GGGCYQHHVPAICDEINGRSEFLTAYAG-EPYEDHGRFQALWEYCSMMGELLHLDVVSIPTYDGLQAAATACCMAARYT- 158
256391229  75 GAGCYRHHVPAVVEEIANRSEFLTAYAG-EPYEDHGRFQALWEYQSLMGELLELDVVNVPTYDGFQAAGTALRMAGRVT- 152
218883609 165 -GRRKILLPANMNPLHKRVVETYVKPH---G-LKLETIPYdrel--gtvDVEALKSMI-D-NDTAAVYIQYPNFFGIVED 235
111025249 158 -QRAEVAVVRAIDPERLSVIRNYCEPTemeShIAVRLIDYdpas--gliDLDDLRAAV-G-EHTAAVYFETPSYLGVIEH 232
271968917 155 -GRSKVLVSGAVSADKMSKLRDFLAHD-----IEIVVAPVgaggeigdvEID---------ETFAAIYLETPNVYGVVET 219
240103758 152 gKRKRFVIPKAISPEKKAVIETYTRGA---N-LEIVEVPWdes---grlDIEKLKEAV---EDSAGVYVEMANFFGLVEE 221
242398920 154 -GKKKFIVPGHLHPERKKILHTYTAGP---G-LEIEYVKWnen---gqvDIEDLKEKA---TDAAGIYLEVPNFFGLIEE 222
226315349 159 -KRTELLVSKNIHPDKLMIIKNYTSPD-----LTVTLIDFenet--grlDLNDLKAKL-S-VDTAAVYFENPTFLGSVEV 228
294102736 160 -GRQEVLVAENIHPETMSVIKNYCNPD-----LTIAYVPCdpkt--gclDLQKLQSLV-S-SKTAVLYFENPSFIGTIDP 229
291300223 155 -GRGRVVIATPIDPDKLSKIEDYLDGAltig-------------------------gelDgDDLAAVFVDYPSYLGVVDR 208
121609415 159 -GRQRVLLAGNLSPDKCSHIRTYGRST-----IVFDSFAFdavt--gsiDQSALAAQL-G-PDVAAVCIDNPNYFGAIED 228
256391229 153 -GRRRLLLVGPVDPDKMSKIEDFVRPD---HdVEVLDGTD---------DGWQAADLVvG-ADVAAVYIEAPNYHGVLDP 218
218883609 236 kAKAIGEIAHEKQALFITGVYPVALGILKPPGELDADIAVGEGQSLGLGMNYGGPHLGIFAIKYdmNLVRQMPGRIIGLT 315
111025249 233 qGAEIAAIARAVGAETIVGVDPISLGVLSSPVDFGADIVVGTTQPLGIHMHTGGGVGGFIASRDedRYAHQYPTLFISIA 312
271968917 220 rGRELADLAHGAGALLVVSADPISLGVLAPPAAYGADIACGDIQSLGMHQSYGGGHAGYIATRDeeRLVAEFPSRLFGIA 299
240103758 222 nVREIGEIAHEAGAYFVVGADPTMLGIFEAPGELGADIAVGEASYLGNPMNFGGPRAGVFAVRNdkKLIRQMPGRIIGMT 301
242398920 223 qIKEIGEIAHESGALFVVGVDPTILGIIEAPGELGADVVVGEASFLGSALNFGGPRAGIFAVKNerRILRQMPGRVIGMT 302
226315349 229 nGQIIADLAHAAGAICVVGVDPISLGVMEAPANYGADIVCGDLQPLGVHMHYGGGQSGFIATHDdpTYVMEYPSRLFGIA 308
294102736 230 nGEKMAEILHNAGALMVTGVDSSSMGLLTPPSRYGADIVCGDIQPLGMHTYYGGARGGFMGVRDdeTFIKEYPSRLFGIA 309
291300223 209 kTAEYVRTAHDLGALAVVACDPVALGVLAPPASFGADIVCGDIQPLGMHPQYGGGHAGFIATRDeeRFVMEFPSRLFGIV 288
121609415 229 -GPALARLVHASGALLVVGVDPGSLGVLTAPGDYGADIVCGDIQTLGMHMNYGGGHGGFIATRDepALVMQYPSRLFGIA 307
256391229 219 aLPLLAERAHAVGALLVVGCNPISLGVVASPASYGADIVCGDIQPLGIRMSFGGGNAGFIATRDeqRLVREFPSRLFGVV 298
218883609 316 TTIDgGDKAFAMVWQAREQHIRREKATSNICTNEALMAVAAAVYMALLGRTGFRRLAELIYYRAHYAASRISEIGLRRV- 394
111025249 313 ETIKpGEYGFGLGLFEQSSYGLRDKGNDWTGHSVYMWAIAATTYMALMGPQGFEDVGGLILQRAHYAAQLLSEIDGVRVa 392
271968917 300 PTAVpGEYGFGDVFYDRTSFAHREEGKEWVGTAAALWGITAGVYLALMGPEGMRELGETVLARTRYAMDRLAAAGARVL- 378
240103758 302 RDAE-GKRAFVMTLQTREQHIRRAKATSNICSNEALVAVASAIHLATLGPKGLRELGEVILKNTAYLKKRLSEVAEIPF- 379
242398920 303 KDAD-GKRAFVMTLQTREQHIRRAKATSNICSNEALVAVAAAIHMATLGPKGLQKLGEIILKNTKYFKERISEVAEIPF- 380
226315349 309 PTEVeGEYGFGDVAYDRTSFAKREKGKESVGTQTALWGITAGVYLATMGPVGMEEVGQGIMQRSQYAAKRLSSIPGVEAk 388
294102736 310 PTSH-GEWGFGDVAWERTSFAERENAKEFVGTAAALWGITAGVYLALMGPKGMKELGESIYVRCQYLMKRMEELPGVKIp 388
291300223 289 PTTVeGEYGFGDVAWDRTSLGVREQGREWVGTAAALWGITAGVYLALMGPQGMRELGEGLMSRCAYAMSRIGEIPGVEIv 368
121609415 308 PTEVpGQYGFGDVAYQRTSFDKRENGNEFVGTAAALWGITAGVYLASMGPQGMAELGEGILQRVAYARAQIAAIPGVRL- 386
256391229 299 PTVVeGEYGFGDVFYDRTSFALREEGKEWVGTAAALNGIMAGVYLALMGPHGMREIGETILALTAYAQERLAAVPCVSAp 378
218883609 395 -F-KAE---FFNEFPISF----NeagV--KYSVIHEKLLEHGLHGGLYIGGYYPELGETALYAFTELHSVKAIDRLIEVL 463
111025249 393 -F-PSG---FFKEFVINF----DntgK--TVEEINDALLNIGIFGGKDLTRDFPELGASALYCVTEIHTKADIDRLVGAL 461
271968917 379 -HpGAV---HFREFAIEV----P------SADDLLAALRGHGIFGGVRLDDRT------LLVCVTERHSKDDIDRLAAAV 438
240103758 380 ---EGL---YFKDVPVKF----K---R--PYGEIHEALLAKGIHGGYYIGKHFPELGETALFAATETTRKEWVHALIEAL 444
242398920 381 ---DGI---NFKDVVVKF----E---I--PYDVIHEELLKRNIHGGFYLKPHFPELEESALLAVTETTRKEWIDALVTNM 445
226315349 389 -F-AAP---FFKEFVIDF----SqtgK--TVKDINAALLAKGIFGGVDLTEHYPELGQCALYCVTEIHTQEDIDTLVTAI 457
294102736 389 lA-STA---HFKEFLVNF----DgtgK--TVQKINKALLDKNIFGGLDVSKIFPGYGECALYCVTETVTQEDMDTLITAL 458
291300223 369 dA-ALP---HIKEFAVRFtg-----gA--TVAMVNAALHERGIFGGKDLSADFPELGQSALYCVTEMHTKADIDRLAAEL 437
121609415 387 ---AHPgsaHFKEFVVDFnatgR------SVATINALLREHAIFGGHDLSGLFPQLGQAGLYAFTELHSQADIDTLVQTL 457
256391229 379 nGeAGAglvSFADFVVRF----T---GllTAADINALLLERGIQGGKVLSETD------ALFCVTEVHTREDVDRLAAVL 445
218883609 464 GKVIR 468
111025249 462 REVTA 466
271968917 439 QEELS 443
240103758 445 KEVA- 448
242398920 446 REIIN 450
226315349 458 KNIV- 461
294102736 459 AEILA 463
291300223 438 KEIVK 442
121609415 458 ALVTR 462
256391229 446 EEIAK 450
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