Conserved Protein Domain Family
FabG

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COG1028: FabG 
NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family [Lipid transport and metabolism]
NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family is part of the Pathway/BioSystem: Fatty acid biosynthesis
Statistics
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PSSM-Id: 440651
Aligned: 797 rows
Threshold Bit Score: 86.3781
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
COG1028 is classified as a model that may span more than one domain.
COG1028 is the only member of the superfamily cl43311
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_013286496    1 MAg-------------vLSGRVAVVTGAARGIGRAAAVALAEAGA-D-VAGMDVagpvspildlppaTP----------- 54  
YP_096243       1 -----------------M--N-ILITGGSSDIAQAIAKRRSESGD-K-IIITCS-------------NDi---------- 35  
NP_285518       1 ---------------meFQNKIVVVTGGASGIGLALATRFVQEGA-T-VITSDR-------------NA----------- 39  
WP_011146330    1 MHk--------------YNSK-ILIIGSSSEIGNAICRHAVASGY-E-VLGTSR-------------KP----------- 39  
WP_106473767    1 ---------------meLKDKIIVVTGAAGGIGRAMALRFAREGA-ShVVCTDL-------------NG----------- 40  
WP_082076191 2524 sqsnddiqeklpiskkyeQQDVVLITGGTRGIGAVIAKHVVSQGVkN-LVIMGR-------------EElpkpnewnqyl 2589
WP_126310275 8286 sqaddeireklhipenysKDDVILITGGSRGIGAAVAAHVVSRGAeN-LAIMGR-------------EAlpepsqwekii 8351
WP_011589036    1 MTdiqqqalnyqcaedtFKGRIILVTGAGAGIGRSAALALAAHGA-T-VILLGR-------------TQ----------- 54  
WP_108601067    1 MQdivn-------etncLEGKVILVTGAGAGIGKAAAFAYAQHGA-E-VILLGK-------------TT----------- 47  
WP_015871041    8 Aa--------------lLQGRTILVTGASAGIGREAALSYARHGA-R-LILLGR-------------DA----------- 47  
WP_013286496   55 -----EDLAET---GRRVTAAG-ARWSAHVADQ--RDIGAVRAVAEAVEREHGGVDVLFANA--GIQAF-AP-LLEMTDR 119 
YP_096243      36 ------SLNQT---LAIYRQQN-IDVTGFIYNF--SDPQACEADLELILKE--PLDGIILNAftRVTQL-RK-LHALPYH 99  
NP_285518      40 -----EVGAQK---AQEI---G---ARFIPADI--SREEGVQAIIENVLAQEGRIDLFCSNA--GVAQGeGP---ETPDK 98  
WP_011146330   40 -----RN--------EEI-----------YLDV--MSDNSVREAIGIAVEKMKCIDAVIYTP--AISLD-GL-LHAQDIE 89  
WP_106473767   41 -----PGAEAT---AAEI---G---GTGLRVDV--ASETEIAALIERVETETGPIDLFCSNA--GVLAAgGV---EIPNE 99  
WP_082076191 2590 knkekPEVEEKlrrMQSFIDQG-VKVNYFNTSL--TDQDGINNMVHKVNQDLGPITGVFHCA--GVINK-NPaFIKKSIA 2663
WP_126310275 8352 askekPELEEKlriMQSLIDRG-ARIRYYNTPL--TDEEGIKTIAQAIRQDLGPITGVFHCA--GLVSK-NPaFFKKPLP 8425
WP_011589036   55 -----EKLEAV---YDEIKAAGgPEPALAPVNLtvARPEDFQELAGLFDKEFGRLDGILHNA--SMLGDiTP-MDRYATG 123 
WP_108601067   48 -----KKLEQT---YDEIEKAGyKQPAIIPLDLkgATEQNYIDMANTIISQFGRLDGLLHNA--SALGGiMP-IDQYPLD 116 
WP_015871041   48 -----ERLDTV---SRQIIADGaPCPHVLCCDLmtLSPSQSQALADDLARRFGHLDGLLHCA--GLLGSiTP-LAQQAYS 116 
WP_013286496  120 HWHDQIDVNLTGAANVLRAFA--PLLVRrgGGRIVVTSSTQGQHG--TTNGSAYSASKWGLIGLVKSAALELG-PHG-VT 193 
YP_096243     100 AVRTYLDNNLNGNIWLIHRLL--PALLKnkFGRLVLISSLSATAG--TSRYPVYCTAKAALEGLFFNLAVDYS-ANN-IL 173 
NP_285518      99 VWDLVHRINVMSHVWAARHLL--PHFLErgEGHFLNTASAAGLLT--ELHSAPYAVTKHAALAFAEWLAVTYG-DRG-IK 172 
WP_011146330   90 GWHDVFNVNLFGAARVAKYLL--PHFMKnrNGVMQFISSTASLRG--ETGATAYSCSKAAMNALVKNISNDYG-RFN-IR 163 
WP_106473767  100 DWQRLWDINVMSHVWAARHLV--PRMATrgGGYLLNTASAAGLLN--QVGSAPYGVTKHAAVGLAEWLAMTYG-DDG-IK 173 
WP_082076191 2664 DMEAVCEPKMKGLVTLHKALEneP-LA-----FFILFSSISSVVPtlSAGASDYAMANNYMDYYAQYQIGQ-----GkSY 2732
WP_126310275 8426 DFAAVCEPKMTGLVNLHRALLqeP-LR-----FFILFSSISSIAPtlSTGQSDYAMANAYMDYYAQNQAGE-----GkTY 8494
WP_011589036  124 TWDSVMQTNVNSAFYLTQAML--PLLRAsdDARLLFTSSSVGRKG--RAFWGAYAVSKAATENLAQVLAEELEnTSN-IR 198 
WP_108601067  117 MWNEVMQVNVTSQFMMTKALI--PALKLaeKPSVIFTSSSVGRKG--RAYWGAYSVSKFATEGMMQVFADEFE-FHP-IK 190 
WP_015871041  117 EWQSVMQVNLNAAFLLTRDLL--PLLRRagRASIIFTSSSVGRAG--RAGWGAYAVSKFATEGVMQVWAQELA-GST-IR 190 
WP_013286496  194 VNAVIPGL-VDTALTRhrdryvqAlveagkpasgdlaqveDAAIQALRSKTP--LGVp---WVEPEDVAPLVVFLASDAA 267 
YP_096243     174 SNIVRVGL-IKTSRTE-------Qfw------------knPAYQEKVIQIIP--QGT----MGEPTQVAEAIDPLLS-KT 226 
NP_285518     173 VTCLCPEG-VWTPMV-------------------------------QNAPIL--QQT----AITTDELVEKALEVLRAD- 213 
WP_011146330  164 AYTVMPGY-VDGGMLR-------Hi--------------sPEKKMEFARSTA--LRR----MADINEIASFCVGTLS-TS 214 
WP_106473767  174 VSVLCPQA-VRTDMTR----------------------------GHEDHVAA--IDG----MIEPDSVAEACVQAIRDE- 217 
WP_082076191 2733 FKSIQWPawgETGMTK-------Gg-------------------lR----TPayMKTglvsITT----ADGLTFL--D-- 2774
WP_126310275 8495 IKSIQWPawgETGMAT-------Gg-------------------mR----TPayVETglisLKT----ADGLAFL--D-- 8536
WP_011589036  199 VNTVNPGG-TRTDMRA-------Ma--------------yPG--------ED--PLT----LKTPADIMAPYLFLLGPDS 242 
WP_108601067  191 FNSINPGA-TATRMRA-------Ka--------------yPA--------ED--PNT----LKQPADLMPLYVQLMS-DV 233 
WP_015871041  191 VNAINPGA-TRTAMRA-------Sa--------------fPG--------ED--PQT----LRTPAQIMPLYLYLMGDDS 234 
WP_013286496  268 RMV--SGTSFA------AT-AG-----D-------------SA 283 
YP_096243     227 SFM--TGSVVT------VS-GG-----L-------------PL 242 
NP_285518     214 GFL--ITTHDT------TL-KS-----FrnkaenydvwiskMR 242 
WP_011146330  215 TYI--TGTSLC------ID-GG-----L-------------SG 230 
WP_106473767  218 TFL--VLPHPE------VL-GY-----LrnkaenydrwiggMR 246 
WP_082076191 2775 -IIesTSQIVNlpc-vvVP-GEfmhnqLlk----------pTI 2804
WP_126310275 8537 -IIrkTPHIVSlpc-vvVP-GEftperLlkiipgkkepgqsar 8576
WP_011589036  243 RNV--TGASIDaqpk---------------------------- 255 
WP_108601067  234 YTK--TTQALDaqpk---------------------------- 246 
WP_015871041  235 LGE--NGRSLDaqpgrrPGkAG--------------------- 254 
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