2FDC


Conserved Protein Domain Family
UvrB

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COG0556: UvrB 
Excinuclease UvrABC helicase subunit UvrB [Replication, recombination and repair]
Statistics
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Structure
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COG0556 is classified as a model that may span more than one domain.
COG0556 is the only member of the superfamily cl33948
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2FDC_A         4 RFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPH 83 
WP_012573340   2 NFELVSNFRPAGDQPQAIHSLVSRVKQGVSYQTLLGVTGSGKTFTMANVIAQIGHPALILSHNKTLAAQLFKDFKEFFPH 81 
WP_013063438   3 KFILTSEYKPTGDQPEAIRQLTEGLDRGDRAQVLLGVTGSGKTFTMANVIAQHNRPTLILSHNKTLAAQLYEEMKGFFPQ 82 
WP_009459603   5 TFILHSSYTPAGDQPEAIARLLSDIEEGATHQTLKGITGSGKTFTMANVIHRLKRPTLILAPNKTLTAQLYGEMKHFFPE 84 
WP_013598987   2 QFEIKSTFEPTGDQPQAIKKLAQGVLDGDKYQTLLGVTGSGKTFTIANVVTEIQRPTLVLAHNKTLAAQLYMEFKEFFPD 81 
WP_013687364   2 DFQLVSEFKPTGDQPEAIKQLVKGIDDGHFAQTLLGVTGSGKTFTMANVIQQTGKPTLILSHNKTLAAQLYGEFKQFFPN 81 
WP_014789995   2 DFKIVSNYSPTGDQPRAIKQLSQGILNNDKYQTLLGVTGSGKTFTIANVVQEVQRPTLVLAHNKTLAAQLYMEFQEFFSN 81 
WP_014937655   2 KFKLHSEFKPTGDQPQAIDKLVSGIEQGQPYQTLLGVTGSGKTFTIANVVNTVQRPTIVLAHNKTLAAQLFMEFKEFFPE 81 
WP_096684892   2 RFKLSSNFTPTGDQPSAIKKLVSGLDKGIKHQTLLGITGSGKTFTMANVIEQIQRPTLILAHNKTLAAQLYLEFKNFFPE 81 
WP_128152183   2 KFEVVSPFQPTGDQPRAIESLSKGILNNERYQTLLGVTGSGKTFTIANVVQNIQRPTIILAHNKTLAAQLYMEFKEFFPN 81 
2FDC_A        84 NAVEYFVSYYDYYQPEAYVPQTDTYIEKDAKINDEIDKLRHSATSALFE-RRDVIIVASVSCIYGLGSPEEYRELVVSLR 162
WP_012573340  82 NAVEYFVSYYDFYQPEAYLPISNTYIEKDFGINAEIERMRIASVSALLSgRQDVVIVSSISCLYGMGNPEDYRENIVSIK 161
WP_013063438  83 NAVEFYVSYYDYYQPEAYLPTTDTYIEKDLAINDEIDRLRLSAVSNLLSgRNDVVVVSSVSCIYGMGSPVALQENVIELK 162
WP_009459603  85 NAVEYFVSYYDYFQPEIYMPGTDRFIPKDSAINDHLERLRLSTTKSLIE-RRDVIVVASVSSIYGLGDPEAYRALQIALS 163
WP_013598987  82 NAIEYFVSYYDYYQPEAYLPSSGTYIEKDLSINEEIEKLRLSTTSSLLSgRRDILVVASVSCLYGIGNPTEFHKNVISIE 161
WP_013687364  82 NSVEYFVSYYDYYQPEAYLPVTDTFIEKDMQINDEIEKLRLSATSALLSgRRDVIVIASVSCIYGIGNPNEFANSIIPIH 161
WP_014789995  82 NAVEYFVSYYDYYQPEAYIPHSGVYIEKDLSINDEIEKLRLSATSSLLSgRRDILVVASVSCLYGIGNPTEFHKNVIKAE 161
WP_014937655  82 NAVEYFVSYYDYYQPEAYIASTGTYIEKDLSINEEVEKLRLSATTSLLSgRRDVLIVASVSCIYGIGNPTEFNKSLIELE 161
WP_096684892  82 NLVHYFVSYYDYYQPESYLPQSGTYIEKDLSINEEIELMRLATTSALFSaRRDILVVSSVSCLYGMGNPHDFKEKTIELR 161
WP_128152183  82 NAVEYFVSYYDYYQPEAFMPTTNTYIEKDLSINENLEKLRLSASSALLSgRRDVLVVSSVSCLYGIGNPQEFQKNLVALE 161
2FDC_A       163 VGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASrDEHCIRVEFFGDEIERIREVDALTGEVLGEREHVA 242
WP_012573340 162 RGMTMLQTIFLRKLVTGMYSRNQIDFTNGRFRVMGDTVDVFPAY-SDMALRVIFYGDEIEKICTFNPVNGQVLEIFEQYD 240
WP_013063438 163 KGQILDRNALLRKLVAALYVRNDLDLQRGNFRVKGDTVDIAMAY-SEVVLRITFWDDEIDAIEEMDAVTFDRLASFDEYR 241
WP_009459603 164 PGVKLNQRELIRRLALLQYDRTERTLKRATFRAQGDVIDIFPADsEHRAVRVELLDDSVASVQWLDPVTGKTLGAIDHYL 243
WP_013598987 162 QGQIISRTHLLHKLVQSLYSRTEGAFLRGNFRIKGDTIDIYPAY-ADDGIRLSYFGDEVEEISIFDIETGKTITKLEKIN 240
WP_013687364 162 VGQLFPRNKFLLRLVENLYSRTEAEFKRGTFRVKGDTVDIHLAY-ADYALRVEFWGDEIERIRTIDPENNSEIEIFQEIQ 240
WP_014789995 162 VGLEVSRTHFLHQLVNALYSRSMVDFGRGNFRVQGDTVEIFPAY-ADDGIRFHFYGDTIEEIESFNVESGKRISGFDKIN 240
WP_014937655 162 LQSKISRTDLLHKLVSALYSRAVNEFVRGSFRVKGDVVDIFPAY-ADNAVRIRFFGNEIDKIQSFDPVSGNIMGDFNKIN 240
WP_096684892 162 IGMQIDRNSLLRMLVSSLYNRTEEKFSRGTFRVRGDIVDVYPSY-LDEIFRIYFFGDEIENIETLEPKFNRKLSQFDSIS 240
WP_128152183 162 VGQKITKTKLLQSLVSALYSRSEMNFGRGNFRVKGDVIDVFPAY-SDTGIRIQLFGNEIDRIENVDYVSNNVIDSIENIN 240
2FDC_A       243 IFPASHFVTREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFCSGIENYSRHLALRPPGSTP 322
WP_012573340 241 IYPAGLFTTTQDRVVVAVRQIEADLNQHICFLNGLGKIQEARRLHERVRFDIEMIRQLGYCSGIENYSRYFDGRQQGDRP 320
WP_013063438 242 LYPANLFMTSQEQTNIAIHQIQDDLMKQVLYFEEIGDNIKAQRIKERVEYDMEMIKELGHCSGIENYSRYFDGRQAGERP 321
WP_009459603 244 VSPKTLFAPPTNKIDSASKKILADMEERVAELNRNNRLVEANRLYERITHDVEMMREVGYCSGMENYSCYFSERDPASPP 323
WP_013598987 241 IYPANLFVTSKETLNDAIHNIQLDLGKQVDYFIEIGKTLEAKRLKERTEFDLEMIKELGYCSGIENYSRYLDGREPGTRP 320
WP_013687364 241 IYPANIFVSSPETTRKAIDQIGEDMVIQVENFKREKKILEAKRLEERTSYDMEMMRELGYCSGIENYSRYFDQREPGTRP 320
WP_014789995 241 IYPANIFVTSPETLNNAIKNIQIDLGKQVEYFQNMGKMLEAKRLKERTEFDIEMMKELGYCSGIENYSRYLDGRLPGTRP 320
WP_014937655 241 IYPANLFVTSKETMNDALRKIQDDLMRQVDFLNKIGKNLEAKRLKERTELDLEMIKELGYCSGIENYSRYMDGRNPGSRP 320
WP_096684892 241 IYPANLFVTSKEKIKHAIDNIALDLGKRKEEFRIKGASIEAKRIEERTNFDLEMIKELGYCSGIENYSRYLDGREEGSRP 320
WP_128152183 241 IYPANLFVTSPDTLSQAIKNIQIDLGKQVEYYNEIGKSLEAHRLKERTEFDLEMIKELGYCSGIENYSRYLDGRAPGSRP 320
2FDC_A       323 YTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELE 402
WP_012573340 321 FCLIDYFPGNFLMIIDESHVTIPQIRAMYEGDQSRKMNLVEYGFRLPAALDNRPLTFDEFESITPQKIFISATPAEYELR 400
WP_013063438 322 YCLLDFFPDDYLLIIDESHVSVPQISAMYGGDRSRKQNLVEYGFRLPAAFDNRPLKFEEFQQEVNQVIYVSATPADYELN 401
WP_009459603 324 ITLLDYLPKDGLLFVDESHVMVPQISAMYRGDQARKETLIDYGFRLPSSKNNRPLNFGEFEKVKPQTIFVSATPGDYELR 403
WP_013598987 321 FCLLDYFPDDYLMVIDESHVTVSQVHAMYGGDRSRKENLVEYGFRLPAAMDNRPLKFEEFESLQNQVIYVSATPAKYELE 400
WP_013687364 321 FCLLDYFPDDYLMIVDESHVTMPQIRAMYGGDRARKINLVDYGFRIQAAMDNRPLMFDEFQTLINQIVYVSATPADYELE 400
WP_014789995 321 FCLLDYFPEDYLMVIDESHVTVPQVHAMYGGDRSRKENLVEYGFRLPAAMDNRPLKFEEFEAIQNQVIYVSATPANYELE 400
WP_014937655 321 FCLLDYFPNDYLMVIDESHVTIPQVHAMYGGDRSRKENLVEYGFRLPAAMDNRPLKFEEFESMQNQVIYVSATPADYELE 400
WP_096684892 321 FCLLDYFDDDFLMIIDESHVTIPQVHAMYGNDKSRKENLVEHGFRLPSALDNRPLKFEEFEQLQNQTIYVSATPADYEID 400
WP_128152183 321 FCLLDYFPKDFLMVVDESHVTLPQVHAMYGGDRSRKETLVEYGFRLPAAMDNRPLKFEEFEMMQNQVIYVSATPADYELQ 400
2FDC_A       403 HSpG-VVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKT 481
WP_012573340 401 MCeGiIIEQVVRPTGLLDPIIEVRSTLHQIDDLMEEIRQRLEKNERTLVTTLTKRMAEELNSYFVNLNIQAAYIHSDIKA 480
WP_013063438 402 EAeGvVVEQVIRPTGLLDPEIEVRPSENQIDDLMDEILTRSHRGERVLITTLTKRMAEELTEYLLNHSVKTAYIHSDVAT 481
WP_009459603 404 VSkDrVVEQVIRPTGLLDPKVEVRKADGYIDDLLAEISKCVKKKNRVLVTTLTKVSAEELTDFLTDNGIRARYMHSDIKA 483
WP_013598987 401 KSeGvVVEQVIRPTGLLDPIIEVRPSQNQMDDLMEEIQKRVDLDERVLVTTLTKRMAEELTKFLVKYGIRTNYIHSDIDT 480
WP_013687364 401 QSeGvVVEQLIRPTGLLDPIIEVRPSLNQIDDLIEEMQLRIEKDERTLVTTLTKRMAEELQKYLDKLGIACRYIHSDIDT 480
WP_014789995 401 KSdGvIVEQIIRPTGLLDPIIEVRPSQNQMDDLMEEIQKRAEIDERTLVTTLTKRMAEELTKFLTRYGVRTQYIHSDVDT 480
WP_014937655 401 KTqGeYVEQIIRPTGLLDPIIEVRPTLNQIDDLMEEIQKRAEEDERVLVTTLTKKMAEELTKYFTKFGIRTRYIHSDVDT 480
WP_096684892 401 KSqKvIIEQIIRPTGVLDPIIEVRPTENQIDDLIEEIRKRTVKDERVLVTTLTKRMSEELHKYFDKISILCRYIHSDVDT 480
WP_128152183 401 KSeGvFVEQIIRPTGLLDPEIEVRPSLNQIDDLMAEIQKRIEEDERVLVTTLTKRMAEELTKYLTKFGIRTRYIHSDIDT 480
2FDC_A       482 LERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSME 561
WP_012573340 481 LERVGIIDEFRRGVFDVLIGVNLLREGLDLPEVSLVAVLDADKEGFLRSYRSLTQIAGRAARNINGKVIFYADKMTKSMR 560
WP_013063438 482 LDRVKILSDLRQGVYDVLVGVNLLREGLDLPEVSLVAILDADKEGFLRSHRSLTQTAGRAARNVNGKVIMYADTITASMQ 561
WP_009459603 484 EDRVEIINGLRAGEFDVLIGISLLREGLDIPEASLVAILDADRAGFLRSAHALIQMIGRVARNENGKAILYADAVTPAMK 563
WP_013598987 481 LERVKIMADLRAGLFDVLVGVNLLREGLDLPEVSLVAILDADKEGFLRSNRSLTQTVGRAARNVNGLAIMYADKITDSMQ 560
WP_013687364 481 IERVEILRQLRLGEFDVLIGVNLLREGLDLPEVSLVAIIDADKEGFLRNERSLVQTVGRAARNINGRVIMYADKMTKSME 560
WP_014789995 481 LDRVKIMQDLREGLFDVLVGVNLLREGLDLPEVSLVAILDADKEGFLRNHRSLTQTAGRAARNVNGKVIMYADKITGSMQ 560
WP_014937655 481 LERIQIMQDLRAGLFDVLVGVNLLREGLDLPEVSLVAILDADKEGMLRSRRSMIQTVGRAARNINGKAIMYADKMTKSMQ 560
WP_096684892 481 LDRIEILKQFREGVFDVIIGVNLLREGLDLPEVSLVVILDADKEGFLRSYRSLTQTIGRAARNVNGMAIMYADNITRSMS 560
WP_128152183 481 LERVEIMQDLRLGKFDVLVGVNLLREGLDLPEVSLVAILDADKEGFLRSHRSLTQTAGRAARNIHGKVIMYADKMTDSMK 560
2FDC_A       562 IAIQETKRRRAIQEEYNRKHGIVPRTVKKEIR-DVIRATYAAEETEM-------------Y--EA-------KPAAAMTK 618
WP_012573340 561 NTIDDTNKRREKQLLYNKRNRIIPKQVQKSVS-TSSLVLHTNTKLNI-------------Kf--AfnietvfKEASTMSH 624
WP_013063438 562 LTIDETLRRRLKQMKYNEEHHITPKQIVKNLSfNALQKENRADTKELmrnfsmaaengdaGvrVAa-----dPIEERMTR 636
WP_009459603 564 QAIDETNRRRQLQIAFNEENGISPASSVRKLA-GEETNTEEPT---------------------Vh------sEAfCENL 615
WP_013598987 561 QTIDETNRRREIQHQYNIEHGKTPQPLHKKII-SLNKQAESFELnpye---------qkhLiaEAa------eNTELYTS 624
WP_013687364 561 RTISETERRRAMQIEYNEAHGLVPTALNKSTE-VILKSTKVADGDPEtrsqky-tpyeagTglFAa-----ePTVNYKDP 633
WP_014789995 561 QTIDETARRREIQIKYNKDHNKTPQPLHKKIT-RIQQEAEFEQnpyv---------rkeaSlrQVa-----eQQAS-YGE 624
WP_014937655 561 ATIDETNYRREKQMSYNEANGLIPQPLNKKIS-DVLVGHTP-DFpkqey-------iqkeIvkQVa-----eTKVSYGNA 626
WP_096684892 561 RTIEETHNRRQRQIEYNSANGIIPKMLKNSTS-AIRKGSNSFEKTN------------------Akn----teNQIYHNI 617
WP_128152183 561 KTIDETSRRREIQNQFNIDHHITPKPLNKKIT-KISIGDQEAAIetyn---------vkdDikTAa-----ePSVQ-YNN 624
2FDC_A       619 QEREELIRTLEAEMKEAAKALDFERAAQLRDIIFELKAE 657
WP_012573340 625 IQLEKAINQIRKMMLFASKQFEFLEAAHYRDELIKLENL 663
WP_013063438 637 PQMEKLIEETTRKMKEAAKQLDFLQAAQYRDEIVRLQKE 675
WP_009459603 616 SDLCDQITAKEQQLLEFTDTGDEQRVEDIRRQLDGLYRQ 654
WP_013598987 625 EEKQQQIEKLTKAMEKAAKNLDFIQAASLRDQINALKm- 662
WP_013687364 634 EELEKAIGAKRKQMEKAAKDLDFIEAARLRDELFELQAR 672
WP_014789995 625 VDIEKLIEEKTKAMEKAAKDLDFLQAAKLRDEINELKNQ 663
WP_014937655 627 EDLEKIIAEKQKQMEVAAKQLDFILAAKLRDEIKALKGT 665
WP_096684892 618 DLIKKEIRKTKREMEKASIDLNFIEAAKLRDKIKILKSK 656
WP_128152183 625 ENLEKIISKKQKEMEKAAKNLDFLTAAKFRDEINELKET 663
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