6XP5


Conserved Protein Domain Family
Med6

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pfam04934: Med6 
MED6 mediator sub complex component
Component of RNA polymerase II holoenzyme and mediator sub complex.
Statistics
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PSSM-Id: 461490
Aligned: 117 rows
Threshold Bit Score: 73.7159
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6XP5_F        16 IQWHTNPAVVggSI-HDNSVLFYFR--ESPFYDKTSN---NEVLYQQGLHNQTMMQFLEtrerferrLREM-SGLEFVVA 88  Chaetomium ther...
EFC50470      34 kTWRDELFLRfrPIvNEDTALEYFCnrSNPFYSKKSV---NETLRMQQTGGIIDRNAL---------LEST-EGIRYSVD 100
Q8IKE0        17 IEYVDNIFLSkyMLnNIENAMQYFY--TCPFYTSRSKlclNEKIRTGKI------------------INDDdEGYIFNIT 76  Plasmodium falc...
CAQ41432      26 IEYVDNLYLSknILnNRENALNYFY--TSPFYTSRSHlslNEKIRVGKI------------------ISDDeEGYLFDIT 85 
Q7RNW7        16 IEYVDNIFLSknILnNRENALNYFY--TSPFYTSKSHislNEKIRVGKI------------------IGEEdEGYLFDIS 75  Plasmodium yoel...
XP_001609351  27 cEFIDPRFLAttALdSNHAALDYFY--QSPFYQKYREgslNELMRAGTE------------------VDSQqVGLIFQVT 86 
XP_006681567   9 MSFKDTAFLQllGL-NEHNALDYFS--MSQFYDKSCL---NEQLKMQVRHNELQAQQLD--------GRQM-KGLEYTLW 73 
XP_001581746  12 MAYRNDDFLQmnLLtIGNLFNSYFN--NSPFYDPTCL---NEQVNRYEKFTDIFDE----------------NGITYRLT 70 
EAX94155       3 gaFINKEFIQqeGLtLENIIHPYFE--SSPYYKPERG-----------------------------------SKLEISFA 45 
RMX67135      12 aSFRDTVWLQsfPL-NAQTVLHYFA--LSPFYDRSCN---NERLKMQRLGLDQ--------------LKNL-RGVEYELL 70 
6XP5_F        89 -----------------QEPaetap--------------------------gtgtGVWVINKQT-RRKRqgeeD---EIS 121 Chaetomium ther...
EFC50470     101 sk-------------rsKPP-----------------------------------SLFIIKKEKvEKKD----Rn--APK 126
Q8IKE0        77 ydnln--------ilkeNEPsdfvskh----------------------iyyntnSIFHVSLRQ-KYRL----NnvnCTK 121 Plasmodium falc...
CAQ41432      86 ydnla--------vlkkNEPedlvsih----------------------iyyntnSIFHISLTH-KYNV----KnimCKK 130
Q7RNW7        76 ydnld--------vlkkDEPtdsasvh----------------------iyyntnSIYHIRLTH-IYKL----KnilFKK 120 Plasmodium yoel...
XP_001609351  87 ysnlndvnealanlpplDEPariqh--------------------------ycnsTLFHITLFS-RNLG----QnglTTT 135
XP_006681567  74 yf--------------tPQP-----------------------------------SLYVIRKQT-RLSP----T---RVD 96 
XP_001581746  71 yv-------------qiQEPnflktldpanppkelileteqeiyapekanypittGLCVISKYRtRLQD----HgepIKE 133
EAX94155      46 qphgsav----lsaahlSKPehksv--------------------------svdqGLVVIDEVL-------------NNE 82 
RMX67135      71 pna-----------akqLPQ-----------------------------------QIYIIRKQR-RSSR----T---QVE 96 
6XP5_F       122 VHGTYFLVG--ENVYMaAPTLADIISMRLASASSSISRLLPIAASVQSWS 169 Chaetomium thermophilum var. thermophilum DSM...
EFC50470     127 LLNLYYIAAeaGVVYQ-SPSVYDVIQARSFNSLSLLNQTFKEIQPHVEYT 175
Q8IKE0       122 VIQYFCIVN--GKIYS-TLSFGELLTNKINNIVRNINNLFDSVNNMTNFN 168 Plasmodium falciparum 3D7
CAQ41432     131 IIQMFCILN--GKIYS-SRSFGELLNNKIANIVRNVEKFYDCVNNMMNFN 177
Q7RNW7       121 VTQMFCVFN--GKIYS-SRSFGELLINKINNIVRNIENFYDRVNNMMNFN 167 Plasmodium yoelii yoelii
XP_001609351 136 PIKVYYIIQ--GSIFL-CPPFGSLLRHRLHESIQHFENFYDTLNDIVKWS 182
XP_006681567  97 LVAVYYIVE--GTIYQ-SPTLCQVLANRVRTSLYFTKDALHVARESYRYN 143
XP_001581746 134 LLAQYYMID--ATIYQ-APDLYSLVTSNFRTAIFNLREAIRDADSAYKWT 180
EAX94155      83 IIAKYIVKD--GYILP-APTFYNLIAGRVCSSLNSLQKSIKNVHKVFNWN 129
RMX67135      97 PLAIYYVLD--GTVYQ-APNIHAMLTSRLKKCSYRVNKAFHGLAAGVRFS 143
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