4EWT,1YSJ


Conserved Protein Domain Family
AbgB

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COG1473: AbgB 
Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]
Metal-dependent amidase/aminoacylase/carboxypeptidase is part of the Pathway/BioSystem: Lysine biosynthesis
Statistics
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PSSM-Id: 441082
Aligned: 814 rows
Threshold Bit Score: 185.321
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4EWT_A         4 QLIETLKSKEGKMIEIRRYLHQHPELSFHEDETAKYIAEFYKGKDVEVE-TNVGpRGIKVTI--DSGKpgK-TLAIRADF 79 
WP_012994080   1 -----M-NLDEKIRKLTEDIFDHPELGYEEWHTRTVVCDFLHEVCpELKiTDFArTGFLLSLphAAAK--PyRLCFVAEL 72 
WP_011098941   9 LVCKVIDDNFDKLFNLAGDIENNPELGFKEIKTAEKVCKLFDELNISYK-DKLAlTGVKGKL--KEKSegP-NVAILGEL 84 
WP_125668709   4 KVCAAIDAWAAKVEALAQDIEREPELGFKETKTAAKVTAFLQQLGLAPQ-TGLAlTGVKARV--VSGRpgP-TVAVLGEL 79 
WP_013655385   4 KMKHIFDETIKQTIELAEDIYKHPELGYKEVRTAGKVKEILEAEGIPYQ-DHVAyTGILATL--DSGKpgP-HIGLICEL 79 
WP_013049121   9 QVCQCIDEKKEDLLSLVREIGSHAELGFKEYRTSSVVAAFLKDLGLPVQ-TGLAvTGVKALL--KGSRpgP-TVAILGEL 84 
WP_007960126   9 KICQAIEASKEQIFALGESIYKEPELGFKETKTASKVEEIFRTLGVSYE-KGLAlTGVKGRL--KGKKsnR-TVAILGEL 84 
WP_012864409  12 RVCKAIVDAQPRLRELAESIMAEPELGFKEVKTSKKVQDMFDELGISYT-TGHAlTGVKGRM--KGRDskY-TVAMVGEL 87 
WP_103080107   7 KILNIIDSNKDKIINFGRDIYRNAELGYKEFRTSKRFADLLKSLHLDVQ-EKLAiTGVKGYL--RGNQhdI-TLALIGEL 82 
WP_009015126  12 KVFAAIDAAYDELFDYAKSVAKEPEFGFKEFKTAKKVEAQFDKLGIPYR-NHLAiTGVKGLL--KGGKpgP-TIAILGEL 87 
4EWT_A        80 DALPITEDtglSFASQNKGVMHACGHDAHTAYMLVLAETLAEM--KDSFTGKVVVIHQPAEEv----------------P 141
WP_012994080  73 DAVYQPGH---FHCDPVTGAAHVCGHYTQVGIALALLVRLLENrlYEKLKFGVDFVFVPAEEfldlahrqelkdrgeieY 149
WP_011098941  85 DGVICFDS---ANANKETGASHTCGHNLQITAMAAAALGLKLSniEDKLHGNVSFMAVPAEEfieieyrqklkeegkihF 161
WP_125668709  80 DAIGCPDS---CKADPQTGAAHACGHNLQVATMAAVACGITQSgvLSELSGDAVFFGVPAEEyvelayrnklikegklhF 156
WP_013655385  80 DGVPTLNH---PYANKEDNAAHTCGHYAQIGAMMGVFLSLNKAkvMDQLCGKVTLVVTPAEEfcdleyrkgliaegkikH 156
WP_013049121  85 DGVISPDH---PEVVKGTNAAHACGHNLQIGTMLGAAMGLTWAsaAKELDGSICFMGVPAEEfieiqermerrqkgeihF 161
WP_007960126  85 DAVTCAAH---PGADPLSGAAHCCGHNVQIAILMAVGRALLETgaMEYLAGDVVLFAVPAEEyveisyrnklreegkitY 161
WP_012864409  88 DAILCPRH---PRADDLTGAAHCCGHNVQITNMFAVAIGL--QavMDELAGDVVLFAVPAEEmieidyrnklreqgklkY 162
WP_103080107  83 DALRIPDH---PFVNKETDAAHSCGHNAQLAGVAGAALALSDPevASNLDGDVVFFAVPAEEygeiefknqlreegkivY 159
WP_009015126  88 DAISSPDH---PLADPDTGAAHACGHHMQQSAMLAAAYGLARThaLDELCGNVVFFAVPAEEyvqlayrkklrregklhY 164
4EWT_A       142 PGGAKTMIENGVLDGVDHVLGVHvms-tmKTGKVYyrPGYVQTGRAFFKLKVQGKGGHGS-SPHMANDAIVAGSYFVTAL 219
WP_012994080 150 FGGKAQAIKEGVFEPYDFCVCTHamggdyPEFSTE--INADLDGFLFKYFTFKGQAAHAGfAPWLGKNALSMANLFQTAL 227
WP_011098941 162 LAGKQELIYRGAFDDVDMAMMIHslk-daPKPTVA--LGSSSNGFIGKTIQYIGKTAHAAeAPHTGVNALNAAMLGLMGV 238
WP_125668709 157 LTGKGQLIYEGAFDDIDMAMQMHadk-nmPAATVS--IGESSNGFIGKTIQYVGKTAHAAdAPDQGINALNAAMLGLMGI 233
WP_013655385 157 ASGKQEMIELGVFDDMALILSCHtmgldmNVYDAE--IGAGLNGFLCKKAIFHGKGAHAGsNPAGGINALNAANLAMTGI 234
WP_013049121 162 LGGKQELVYQGAFDDIDMAMMVHagt-nmPHPSFM--IGETGNGFIAKTIRYMGKATHAAaAPHEGINALNAAVLGINAV 238
WP_007960126 162 LGGKQELIHLGAFDDIDMALQIHlltntqVDSFIR--LGSTSNGFIGKLVKYRGKAAHAAmAPSEGINALNAAMLGIMGV 239
WP_012864409 163 MGGKQQLIYEGAFDDIDMAMQMHvetaktPAGEMG--LGSTSNGFVSKLIEYHGKVAHAAqAPHEGINALNAALMGVMGV 240
WP_103080107 160 GGGKSELIRIGAFDDIDISIVHHss----kDGIII--GNGTSNGFVSKVIRYIGREAHAAaEPEKGVNALNAASLAVSAL 233
WP_009015126 165 LHGKGQLIYEGEFDDIDMAMQMHssk-ktPEPTVA--VGTSSNGFVGKTIQYVGRSAHAAdAPDQGINALNAAMLGIMGI 241
4EWT_A       220 QTVvsR-RLSPFETgvVTIGSFDGKGQFNVIKDVVEIEGDVRGLTDATKATIEKEIKRLSKGLEDMYGVTCTLEYNDDYP 298
WP_012994080 228 AYL--RqQLDDSKLvrFNPVLLDGNFGINIIADRAKIGTDLRTNDVDYMIQVAKQLDQAAQGAATALGGAVEIETQMGYL 305
WP_011098941 239 NAL--ReTFRDEDSirVHPIITKGGDTVNSVPADVRMETYVRANNVDAMKITNKKVDKALIAGGYAIGAETIINTIPGHL 316
WP_125668709 234 NAL--ReTFREADVirVHPIITKGGDLVNSVPADVRIETYVRAKTMEAIEATHKKVDTALKAGGDAVGAQTVIDTMPGQL 311
WP_013655385 235 NFL--ReTFREEDAirVHFVVKEGGQTVNTVPERVTMEMYVRAKTVDAILETDQKVTRALRAGALAIGCDLEIIDIPGYL 312
WP_013049121 239 HSM--ReTFRDDDHvrVHFIITKGGDSVNTIPADVRLEAYVRGKTMDAINSTHEKFDRAFRSGGDAVGAKTEIVTIPGYL 316
WP_007960126 240 NAQ--ReTFREEDYvrFHPIITQGGDLVNVIPEDVRMESYVRAATMEALQESNGKIDRALRAGGDAVGAEVSIQSLPGYL 317
WP_012864409 241 NSI--ReTFKESDYfrFHPIINQGGTLVNCVPDYVQVESYVRASNIEAIVDGNHRVNRALKAGGDAVGATCVIKDLPGYL 318
WP_103080107 234 AYQ--ReTFRDEDSvrVHAIITKGGNLVNVIPNEVVIESLVRAKSTEAILDADRKTDRAFIAGSLAIGAGIEITTMPGYL 311
WP_009015126 242 NSL--ReTFRDEDAirVHPIITKGGDLVNNVPDDVRIETYVRAKTMEAIEKTHKKVDAALRAGGMAIGAEVHIDTMPGHL 319
4EWT_A       299 ALYNDPEFTEYVAKTLKEAnLDFGVEMC---EPQPPSEDFAYYAKERPSAFIYTGAAVEngeiyPHHHPKFNI--SEKSL 373
WP_012994080 306 PFVQDRYLSTFVKKAFAKQdKIKKLYEN---RPSAAAGDIGDLSFIMPAIQIGYSGFTG-----RIHGTDFIHt-DLTAI 376
WP_011098941 317 PLKSSLPLNEIFKENSLSLlPEDSVIDA---GHFAASTDMGDVSNLIPAIHPFIGGVSG-----ALHTKDFKVedFYSAC 388
WP_125668709 312 PLACNNRLNELFVTNAKIAePNVAVKDA---GHFSASTDMGDVSHLLPVIHPFIGGVDG-----FLHTADFHVvdFKHAV 383
WP_013655385 313 PLHQDKNLTELVKIHILNYvSSERIAQG---THGFASGDMGDLSSLYPIVEIGVGGFTG-----TMHGCDFRTadYEQAY 384
WP_013049121 317 PLACSAAMNSLFESNAGSFlPHQNIATA---PHFDASTDMGDICHIMPAIHPYFGGVAG-----ALHSGDFRVvdYDAAV 388
WP_007960126 318 PMYNNQDLNQVFRGNAEVLyGQPQVIDG---THEAGSTDTGDLSHIMPTIHPWLACVSG-----ALHSKEYIVtdVHAAY 389
WP_012864409 319 PMRNDERMNALLRENSNPIfGEANVYQG---PHITASTDMGDVSHLMPVIHPWVGCISG-----VLHSAEYEIsvPDVAY 390
WP_103080107 312 PKLSTPA-HPLMIEAAREAaPGRKVKEAdpaSHGAGSTDVGDLQHIMPVLEFNTGGVSG-----AFHSKDFQVidEEEAY 385
WP_009015126 320 PLVCNATLNELLVENAKEAfPSVKIINA---GHFSASTDMGDVSHLMPAIHPFIGGTDG-----LLHGADFKVvdFNAAA 391
4EWT_A       374 LI-SAEAVGTVVLDY---L---K 389
WP_012994080 377 LTtFPDFLVRVLMEMsdgIevaH 399
WP_011098941 389 IL-PGKIMAMSVIDL---LfnnA 407
WP_125668709 384 LL-PAKAFAMMIVDL---LaddA 402
WP_013655385 385 HI-PAAYFIDTIIDL---LsdgG 403
WP_013049121 389 IL-PAKVMATTVIDL---LcngA 407
WP_007960126 390 IK-SAQALAMTIIDL---LygdG 408
WP_012864409 391 IK-TAQALAMTIVDL---LyddA 409
WP_103080107 386 VV-TAKIFALSAYKL---LkegA 404
WP_009015126 392 LL-PGKAFAGMVIDL---LadnA 410
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