5L9W


Conserved Protein Domain Family
HyuA

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COG0145: HyuA 
N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit [Amino acid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]
Statistics
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PSSM-Id: 439915
Aligned: 573 rows
Threshold Bit Score: 552.004
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5L9W_B        13 IDIDVGGTFTDFVLTl--dG-ERHIAKCPTTPHDLSIGFLNAVEAGGdkvg----lsvEEllprID-----IIRYSTTVA 80 
WP_012050404   5 VCSDVGGTFSDLFVFdennG-EWNIFKAFTVPRRPSDGIMAGLRQAAdhygltldgflRD----CV-----SLVHGSTVA 74 
WP_012931941   3 FAIDCGGTFTDLVVGaa---dETRAYKALTVHADPVAGVLDAFDLAAsdlgrtrgqllAD----GE-----LLLHATTRA 70 
WP_012933769   3 FAIDAGGTFTDLVLDs---GrDLRLFKAHTTPHDPVEGVLDVLAVAAagmgmelpellGR----GQ-----RLVHGTTRA 70 
WP_012935854   3 LGCDTGGTFTDLVVDt---GeELRLFKAATTPEDPVRGVFDVLTVAAradgrsledflRD----AD-----DFVHGTTRA 70 
WP_013675347   8 IATDMGGTFTDLVLEdrwtE-RVHIVKSPTVVDDPIQGILAAVDLAAaeigigrrdllAG----TD-----TFVHGTTRA 77 
WP_006523608   5 VCIDIGGTFTDASILde-nG-DINVFKSLTTHDNYLDGMIDVLNVAAeyynetleeflHS----CSpfndgSLTHGSTIA 78 
WP_015098520  32 VSVDIGGTFTDLVVEqg---aALRLFKSPTVPGDPVLGIMNALEMAAdadgvplaeflGR----TG-----SFVHATTRG 99 
WP_067970134   4 ISVDTGGTFTDVVVAdk-dG-KLTIGKALTTRSRVFTGMRNAIGAAAdtlgiaaadllAK----TD-----TLIYGTTRA 72 
WP_066109064   4 ISVDTGGTFTDVVVTdd-qG-RLTVGKALTTPERSFTGLSNSITNAAdqlgislsqllAE----TR-----VMVYGTTRA 72 
5L9W_B        81 LNRLLQRQGPRIGLLTTEGHEDAILIGRgaqwtdgQRVAERRNIAVQnKPLPLIERDLILGVRERIDSSGSVVRPLDEED 160
WP_012050404  75 LNALLEGKVAKVGLICTRGFRDILTTRE-------QGRSEPFLWKTD-YPDPFVPRYLTLPVTERVNSEGGVEIPLNEDE 146
WP_012931941  71 LNAVTEGRTAKTALLVTAGHPDVLSLRE-------GGRHSLFDFATA-TPPPLVPRAWTYEIPERLDRRGRVVRPLDLDH 142
WP_012933769  71 INALVTGATARTGLLCTEGHPDVLVFRE-------GGRTEPFDFTVG-YPRPLVPRALTAELPERITAEGTIFRPLDEAR 142
WP_012935854  71 INAVVTGSTARTALLATAGHRDMLVFRE-------GGRADAFDHTRP-YPAPLVPRSLTFEVRERIGADGHVLEPLDEAA 142
WP_013675347  78 LNAILTGTTARTAFLTTRGHPDVLLFRE-------GGRVDPFDFTRP-YPAPLVPRALTWEVTERVGADGAVVTALDEAA 149
WP_006523608  79 TNAVLERKVAKVGMICTKGFRDVLLFRD-------GPIKNPFDFQLD-YPEPYIPRYRILPVTERINSEGKIDIPLDENE 150
WP_015098520 100 LNAVLTGNTARTAFLTTEGHPDVLLLRE-------GGRQRPFDFTVP-FPEPYVPRSLTFEVRERIGSTGEVLRPLDLAA 171
WP_067970134  73 TNAIVTRNVAKTAFLTTRGFPDILFLRE-------AGKYNAHDFSKD-YPDPYIPRRHTFEVTERISSEGAILLPLDELQ 144
WP_066109064  73 TNAIVERKTAKTALLVTEGFPDVLVFRK-------GGKLNALEINAK-VEPPYIPRSLTFEIPERMNAEGGVETALDEAN 144
5L9W_B       161 VRTKLRMLMDRGARAIVVSLLWSFMNPAHEKRVREIIREEYkeyhiGFVPVVMSHSVVSKIGEYERTMTAVLDAYLQRSM 240
WP_012050404 147 VRAAVRQLRDYGVQAIAVALLWSITNGDHERRIEAIVREEW-----PEVPVVLSSQLNPILREYRRTSSTVVNASLLEVI 221
WP_012931941 143 VGRIAAELAEREVEAVAVSFLWSIVAPEHELAVEALLARAL-----PGVPVSCGHRVNPVLREYRRTVATALDASLKPLM 217
WP_012933769 143 TVECIGELRAAGVEAVGVSLLWSIVNPAHELRVGELLDEHL-----PGVPYTLSHQLNPTLREYRRTSSTCIDASLKPVM 217
WP_012935854 143 LSATLRELAEHDVEAIAVALLWSIVEPRHELRVGDLIAEHL-----PGVPYTLSHQINPTLREYRRASSTCIDASLKPLM 217
WP_013675347 150 LVAQLREIVAAGVEAIAVCLLWSVANPAHEVRVGELVEQHA-----PGVPYTLSHRLNPIVREYRRACSTVLDASLKPLM 224
WP_006523608 151 VRQVIEQFKKWNVQAIAICLLWSVVNPIHEDRIRDIILEEW-----PEVNIVRSSVVNPCIREYRRWVSAAMDASLSPLI 225
WP_015098520 172 LEHTCDRLAATGVEAVAVCLLWSTVNPEHELAVAQVLRRRL-----PDVPVTLSHALNPSLREYRRASSAAIDASLKPLM 246
WP_067970134 145 LRSTLERLREQKFEAVAVCLLWSIANPVHEDKVGTLIREIL-----PDVPFTLSHELIPIVREYRRASATAIDASLKPLM 219
WP_066109064 145 ARATLEKLGRVGVEAVAVALLWSIANPAHERRLGELIEEIL-----PGVPYTLSSSLNPTIREYPRSSATAIDASLKPLM 219
5L9W_B       241 QNDIGATWDKLRAKGyHGAFLMIHNSGG--SADIFKTPASRTFNGGPV-AGLMGSAYFA-NKLGYKNVVAGDVGGTSFDV 316
WP_012050404 222 RTYVSDLQAQLSDNGyARPLSLVTSAGGiaSVQDMMERPIYSINSGPSmAPIAGQTTVA-MEQGIDNVLVVDMGGTSFDV 300
WP_012931941 218 SDYLDDFERRLRAEGfGGRLLMTTSSGGavPLGEVAARPVLSIGSGPA-MAPIAARALPqV-GAAGTAIVADTGGTTFDA 295
WP_012933769 218 ADYFASLEARLAAAGfGGRVLIVTSSGGmlDAADLAAAPIHSINSGPS-MAPVAGRHYAaLEGGHDTAIVADTGGTTFDV 296
WP_012935854 218 TAYFSSLTGRLREAGfGGRVLVATSQGGmlDAGEVAARPIHSLNSGPA-MAPVAGRHFA-AAAREESAIVMDTGGTTCDV 295
WP_013675347 225 TAYLEDMKRRLSAEGlVGRLLIVTSGGGvmDSAAVAAAPVHVIGSGPA-MAPIAGRDVVdRTTGHQTVLVTDTGGTSYDI 303
WP_006523608 226 SKYTMEINQKFKKLGlQGEVGMLNSSGGivTADELVYRPLYAIDSGPAmAPVTGKTYVE-SDLAEENIVVFDMGGTSFDV 304
WP_015098520 247 TEYVAGLTGRLRTAGlTGRILMVTSAGGvvDVLDAADKPILTINSGPS-MAPVAGRAYAtADLGARTVIVADAGGTTYDV 325
WP_067970134 220 QEHLLGLEADLRAEGyTGDIMVSTASGGcsTINALVEKPIYTIGSGPA-MAPLASLAVGqLERAGNNIIVCDTGGTTFDI 298
WP_066109064 220 QKHLRDLKIDLSEAGfGGELLISASSGGvmHIDDVVQKPVYMAKSGPA-MAPLAGIAYTrAEDLDDDVIIVDTGGTTFDV 298
5L9W_B       317 ALVVESSVRnYTFRPVID----KWMVNVTMMQTISVGSGGGSIAKVDRSGtRLEVGPRSAGSMPGPVCYDLGGTEPTVTD 392
WP_012050404 301 SVVQDGKIN-LSREIVMG----GCFLGVDLVDSRSVGSGGGSIARVDAGG-LVHVGPESAGANPGPAFYGRGGTRPTVSD 374
WP_012931941 296 SVVRRGRVA-LTADVWLQrpflGDVTGVPGIAVRSIGAGGGSIAWLDDGG-LLRLGPQSAGSRPGPAAFGRGGEEPTLTD 373
WP_012933769 297 SVVRAGSIP-RTRETWIGpphqGHITGFPSVDVKSVGAGGGSIAWVDDGG-LPQVGPHSAASQPGPACYGRGGTEPTLTD 374
WP_012935854 296 SVVRRGRIP-WTRETWIGppreGHITGFPSVGVTSVGAGGGSIAWVDEGG-LLRVGPLSAGSVPGPACYGRGGSRPTLTD 373
WP_013675347 304 GVVRDGDVS-FTRESWLGapylSHMTGLPSIDIKSVGAGGGSIAAV-VSG-LLTVGPRSAGARPGPVCYGQGGTEPTVTD 380
WP_006523608 305 SCIIEGVIS-VSRETKIG----DEVPGISRIDVNSIGSGGGSIAWVDPGG-MIRVGPHSAGSAPGPACYDKGGIYPTVTD 378
WP_015098520 326 TLVRRGEIP-STRTAWVGdegtGHMTGLPSIDVKSVGAGGGSIAWVDPGG-LLWVGPQSAGSVPGPACYGNGGTDATVTD 403
WP_067970134 299 GLVREGDLT-YTRETWVGeqwtGELLGISSVDMRSVGAGGGSIAWVDSGG-LMRVGPQSAGSEPGPACYGRGGTLPTVSD 376
WP_066109064 299 SLIRDGAIK-YTRETWLGtpmaSTMLGMATVDIRSVGAGGGSIAWVDAGG-MLRVGPHSAGSEPGPACYGRGGDKPTVTD 376
5L9W_B       393 ADVVLGYINPDTYYGGrMPLNKAKAEKAIrEKIAQPLGIETIEAAALIRYIVDENMASAIKREVHMRGYHPEDFVLFAFG 472
WP_012050404 375 ADLVLGYLNTEAFARGgTPLDPALSAAAIeEHVAKPLGIDVAQAAFTMWSTVNNDMQAAMQDLAISRGIDLRDFVVVSGG 454
WP_012931941 374 AAVVCGLLDPADFLGGrLRLDAVAARAAIeRRVGAPLGLDAVAAAEAVLELATEQMAAALDELVAHEGIDPAEAVYVAGG 453
WP_012933769 375 ACLVVGHLAADSFLAGaMRLDADAARSAVsRRIAEPLGLSVEEAAAAIVAVATENMVHAIEEVTVHQGIDPRAAVLVGGG 454
WP_012935854 374 ACLVLGYLNPSAFLGGtMTLDTEAARTAV-EELAAPLGVDVQEAAAAVLTIATSNMLHAIEDVTVAQGIDPAETVLVAGG 452
WP_013675347 381 AAVVLGYLDPGYFLGGrVTLDIAAAERAIaERIAAPLGFTTVQAAAAVMELATEHMVRAIEDTTVAQGIDPAAAVLVAGG 460
WP_006523608 379 ANVVLGYMEADYFNAGrMCLNPELAEKAIyEYIAKPLGLDLNEAAFTVWSTVNANMITAIKEITIQQGIDPREFVAVAGG 458
WP_015098520 404 AALVLGYLDPANFSSGsMTLDARAALDAVtERVARPLGLDPIAAADAVLRLTTEQMAHAIQEITLQQGVDPARAVLVGGG 483
WP_067970134 377 AAVVLGYFDPGFFLGGrMTLNVEAARRAV-ATVADRVGVPVEVAAYQIINLASEQMIKAINDITVKQGINPRESTIVAGG 455
WP_066109064 377 AAVVLGYIDPDRFLGGrMKLDKPAAEAAM-RTVADRLGKSIWETAGAILQISSEIMIKAIEDITTNDGVNPGDSTIVAGG 455
5L9W_B       473 GAGPTHMAGL--KGDIPKAVVFPAAPVFCAMGSSIMDIVHMYEQSRRMVfMEpgtekfvVDYEHFNQTVDTMIERARQEL 550
WP_012050404 455 GAAGMHIQAMamELGIRELIIPKAAGVLSAYGGAFADLVKEYSAIAFVEsNR-------FDFAGVNALLASLEESAVAFL 527
WP_012931941 454 GAAGLNACAIgrRLGCRRLIVPGAGPALSATGALVAPIGTVMTRALATSsAD-------FDHAAAVAALVALDDDATGFA 526
WP_012933769 455 GAAGLNLVAIaaRLGCPRVLIPETGAALSAAGGLLSDVSAGFAATHVTStAA-------FDFAGVERVVGDLRERCAGFL 527
WP_012935854 453 GAAGFNAVEIarRLACRRLIVPEVGAALSAAGALLSDLSTDFSTTLFAAtEA-------FDAGAVNAALAELTVRCRDFL 525
WP_013675347 461 GAGGFNAVAIasRLRCAAAVIPDTGSVLSAAGAAISDLSSDFAAACPAStHE-------FDHDRVGAVIDGLVQRAREFV 533
WP_006523608 459 GACGVHAIPLaeGLNMKKILIPKTAGALSAVGGIFSDVVSEFSKSFYTEtRD-------FDFQGVNEVIKSLYAEAIEFF 531
WP_015098520 484 GAAGLNAVAVaaRLGSRELVIPAVGAALAAAGALMSDLTAVYNTTVPAVtSS-------FEPARVNAALAGLRERCREFT 556
WP_067970134 456 GAAGINIMLIarEMGCSRAVLPRVASALSASGMQFADLVAEEAASFPVVsDR-------FDFARVNAVLEKLTSQLEPYR 528
WP_066109064 456 GAAGLNLLSIarSMKVKNVIIPKTAGAISAAGGQFSDIATDFSTSCYAAsNA-------FDSGQVRETLNGLLAQSGEFE 528
5L9W_B       551 RSEgleVddA-SFGLELDMLYGGQVNLKRMSSPLLhIrt-----aeDALKVYQAFETEFSEAFSPLVvNKPggVFLDNFV 624
WP_012050404 528 DGHgidAadR-RLEYYAEARYPEQIWELPVPLRTGrIad-----qaQLDALVADFHDIHERMYAVKDpSQP--IECLHWK 599
WP_012931941 527 RRAgaaAa--dRLEFEALCRYVDQAWELGIPIERDasd------aiDVTALVAAFHAEHERLLGSAQpGAV--VEVLGLQ 596
WP_012933769 528 RSAevd-gdA-AVELAVEARYPRQNWEIEVPIAAEhVtg-----eaGVRELVAAFHRAHERLFAISDpDSE--VEIITWR 598
WP_012935854 526 ATAgdgA--G-EIEYRAEGRYPHQVWEIDVPVRSGtFad-----daAVEQLASDFHGVHRNLFGIADeGSS--VELVSWR 595
WP_013675347 534 ASTgvaGelA-DVRLFADARYPHQVWEVEVPLPTLrIat-----aaDVEALADAFHKMHEKLFAISDpTSV--VEVVGWR 605
WP_006523608 532 DRNnilEgkR-VLEFYVEGRYPYQVWEIPVALDSDvFneygeldqeGINKLVEKFHEEHEMVFAVKEpEAY--VECIFWR 608
WP_015098520 557 AHVgaaEddA-IVTLFAEARYPQQIWELEVPLRVGaFvd-----gsDVTDFEADFHATHQQILGITDeGSP--VEVVSWG 628
WP_067970134 529 SAVedkAtdV-SIQYIAEARYHTQIWDIDVPLPSArFds-----qaDLDTFVRAFHDAHERILAVRDeDSP--VEVINWR 600
WP_066109064 529 SGLrakGveTfRYQLFVEARYARQQWELEVELPVEwAqs-----cdDVALLEKLFAEQYKRLYAVDRlGTV--VEAINWR 601
5L9W_B       625 LRVTVPTWK-PPIPEy-PLqGTDPSAAFLGKRKAYWPe--TkhWADTPTYQFELLQAGNVIDGPAIVEAELTTIVVPPRQ 700
WP_012050404 600 VRAIGATPK-PAIRKl-PFgGEGADHALKGTRKAFFNdlgG--FVDAAVYDGTRLTCGNRIEGPAVIEEPTTTVVVMPGT 675
WP_012931941 597 LRIEIGELR-TPP----G--FAHGSGAVPPTRRARMg--gA--DLDVQVLDVADV-PRDGILGPAIVRSSLTTVVIPAGA 664
WP_012933769 599 AEVCARATA-SAQRRivR--AEPAALAAATTRPMYVRg-dG--WVDGAVAHVDQLADGVAVAGPAVIGSSFTTVVVDRGF 672
WP_012935854 596 ASARVTVHD-GATRPv-A--RPNGPGAADEARRAYFPg-aG--WQAARAVHAGRIAPGEQVAGPALIESPLTTIVMDGDA 668
WP_013675347 606 VRASCRTRS-TPLGQv-E--SGPARSRAPRSRPVHFPg-hG--RFDAVVRAHDDIAAGEVVAGPAIVETPVTVVVVDPGA 678
WP_006523608 609 VKAIGKRTVvAELKEntKQrERPARDALKGTKKAYFRdlgG--MVDTNVYLGQELRYGNKIEGPAIIVEPTTTIIIYPGY 686
WP_015098520 629 ARVRVPLRE-SGGv--lT--ARLGPAAPPTTRRAYVRg-tG--MTDVPVRSLASIVPGELLPGPLLVESPFTTVVVADAS 700
WP_067970134 601 ARLVASRAK-PDLAGs-V--SFVSAAEAPSHRDCFFGe-eT--AVRTAIFKPAAIRPGLRIDGPAIIEEVTTTLVVYPGT 673
WP_066109064 602 LRVAAVLSS-PQVSWq-G--PGSDIDLNSRDNDAYFLe-tG--HTKTRVINGTTIPLGFEIKGPLIIEEPTTTIVVEPGM 674
5L9W_B       701 RLSIDTHGLAILeAI 715
WP_012050404 676 AMTVSEYGSYVs-RF 689
WP_012931941 665 AVRSDGVGGLEVdLA 679
WP_012933769 673 AARRSPAGSLVItRE 687
WP_012935854 669 VAERGADGTLSIrLT 683
WP_013675347 679 TATRASTGALILrRN 693
WP_006523608 687 ELLVTKLNNYFIs-- 699
WP_015098520 701 TCELSGSGSLIVhPA 715
WP_067970134 674 HVTVSEYGNFLLsF- 687
WP_066109064 675 TGRLSPQGNYIFeFG 689
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