Conserved Protein Domain Family
PRK07232

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PRK07232: PRK07232 
bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed
Statistics
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PSSM-Id: 235976
Aligned: 369 rows
Threshold Bit Score: 1011.17
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
77165066    1 MIFRDEALEYHRRG-RAGKLEVIPSKPCLTQHDLALAYSPGVAEPCREIHRSPDDVYLYTGKGNLVAVVTNGTAVLGLGP 79 
254796783   6 DDLGIQALRYHSKG-RPGKLGVHATKPLLTQEDLSLAYSPGVAHPCLEIKKNPLDAYKYTSKGNLVAVISNGTAVLGLGN 84 
269958273   5 SERDREALEFHCKR-RPGKVSLLPTKPLMTQGDLSLAYSPGVAVPCLRIASDPDTVYDYTARGNYVAVISNGTAVLGLGN 83 
56416389    5 SERDREALEFHCKR-RPGKVSLLPTKPLMTQGDLSLAYSPGVAVPCLRIASDPDTVYDYTARGNYVAVISNGTAVLGLGN 83 
57238851   10 DAKKREALEFHCKGlKPGKVSLMPTKPLLTQRDLSLAYSPGVAVPCLEIAENPDLVYKYTARGNYVAVISNGTAVLGLGN 89 
58616840   10 DAKKREALEFHCKGlKPGKVSLMPTKPLLTQRDLSLAYSPGVAVPCLEIAENPDLVYKYTARGNYVAVISNGTAVLGLGN 89 
58578781   10 DAKKREALEFHCKGlKPGKVSLMPTKPLLTQRDLSLAYSPGVAVPCLEIAENPDLVYKYTARGNYVAVISNGTAVLGLGN 89 
73666751   10 DGKKKEALEFHCKDsKPGKVSLLPTKPLLTQRDLSLAYSPGVAVPCLEIAKNPDLIYEYTARGNYVAVISNGTAVLGLGN 89 
88607511    5 SEKDMEALEFHSRG-RPGKVALLPTKPLLTQGDLSLAYSPGVAVPCIKIASDPDLVYEYTARGNYVAVISNGTAVLGLGN 83 
88658354   10 DEKRKEALEFHCKDlKPGKVSLLPTKPLLTQRDLSLAYSPGVAVPCLEIARNPDLVYEYTARGNYVAVISNGTAVLGLGN 89 
77165066   80 LGPLASKPVMEGKGVLFKRFADIDVFDIELNAPTAEEVIQACQLLEPTFGGINLEDIAAPDCFHIEERLRETLTIPVFHD 159
254796783  85 LGAMASKPVMEGKAVLFKKFADIDSIDIEVDTQSIEEFILTVKNIASTFGGINLEDIKSPECFEIEERLAAMLDIPVFHD 164
269958273  84 IGPLASKPVMEGKAVLFKRFADIDAVDIEVDTEDVEEFINAVKHLGLSWGGINLEDIRAPECFIIERRLGELMDIPVFHD 163
56416389   84 IGPLASKPVMEGKAVLFKRFADIDAVDIEVDTEDVEEFINAVKHLGLSWGGINLEDIRAPECFIIERRLGELMDIPVFHD 163
57238851   90 IGPLASKPVMEGKAVLFKRFADIDAIDLEVDTSDVDEFVNAIKYLGLSWGGINLEDIRAPECFIIEEKLSKIMDIPVFHD 169
58616840   90 IGPLASKPVMEGKAVLFKRFADIDAIDLEVDTSDVDEFVNAIKYLGLSWGGINLEDIRAPECFIIEEKLSKIMDIPVFHD 169
58578781   90 IGPLASKPVMEGKAVLFKRFADIDAIDLEVDTSDVDEFVNAIKYLGLSWGGINLEDIRAPECFIIEEKLSKIMDIPVFHD 169
73666751   90 IGPLASKPVMEGKAVLFKRFADIDAVDIEVDTSDVDEFINAVKYLGLSWGGINLEDIKAPECFIIEKKLSEIMDIPVFHD 169
88607511   84 IGTLAAKPVMEGKAVLFKRFADIDAVDIEVNTEDVDEFINAVKYLGHSWGGINLEDIRAPECFVIERRLSELMDIPVFHD 163
88658354   90 IGPLASKPVMEGKAVLFKRFADIDAVDIEVNTSDVDEFVNTVKYLGLSWGGINLEDIKAPECFIIEKRLSEIMDIPVFHD 169
77165066  160 DQHGTAIISGAALLNACELAGKRLEDIKLVMNGAGAASIACAKFYLTLGVDPDNLLLCDSKGVLYKGREDLMpgrpryNE 239
254796783 165 DQHGTAIIVCAGLINAADVTKREVEELKVIVNGCGAAGIACIELMKEIGI--SDIVVCDQSGVIKKDRDFHD------GD 236
269958273 164 DQHGTAIITLAGIINALDITGRNLKSVKIVVNGAGAAGIACVEMLKFVGIPNDNIVLCDQNGVIYKGRQLGM------NE 237
56416389  164 DQHGTAIITLAGIINALDITGRNLKSVKIVVNGAGAAGIACVEMLKFVGIPNDNIVLCDQNGVIYKGRQLGM------NE 237
57238851  170 DQHGTAIIVSAGLINALDITGKNIKDIKIVVNGAGAAGIACLEMIKLIGVPAENITLCDQNGVIYKDRQLGM------NE 243
58616840  170 DQHGTAIIVSAGLIYALDITGKNIKDIKIVVNGAGAAGIAGLEMIKLIGVPAENITLCDQNGVIYKGRQLGM------NE 243
58578781  170 DQHGTAIIVSAGLINALDITGKNIKDIKIVVNGAGAAGIACLEMIKLIGVPAENITLCDQNGVIYKDRQLGM------NE 243
73666751  170 DQHGTAIIVSAGLINALDITGKNFKNVKIVINGAGAAGIACLEMIKLIGVPADNITLCDQNGVIYKGRQLGM------NE 243
88607511  164 DQHGTAIIVLAGIINALDITGKVLKNVKIVVNGAGAAGIACVEMLKFVGIPNDNIILCDQNGVIYKGRQLGV------NE 237
88658354  170 DQHGTAIIVAAGLINALDITGKSFKDVKIVINGAGAAGIACLEMIKLIGVPAENITLCDQNGVIYKGRQLGM------NE 243
77165066  240 YKAQFIRPTRLRTLPEALAGADAFCGLSVANVVTPDMVRSMNDNPIIFALANPDPEITYPDALAARPDVIMATGRSDYPN 319
254796783 237 RKALYAVDVSANTLEEALVGADVFIGLSAADVLKPEWLTGMNKDPIIFALANPDPEIKPELAKKARPDAIIATGRSDYDN 316
269958273 238 WKLKHAIETKERDLKDAMKGADIFIGLSVRDVLSKEMLLSMNKDPVIFALANPYPEVNPEFAREVRPDAIIATGRSDYSN 317
56416389  238 WKLKHAIETKERDLKDAMKGADIFIGLSVRDVLSKEMLLSMNKDPVIFALANPYPEVNPEFAREVRPDAIIATGRSDYSN 317
57238851  244 WKAKHAIDTKNRSLKDALVMADVFLGLSVKDVLSENMLLSMNKDPIIFALANPDPEINPDIARKIRPDAIIATGRSDYNN 323
58616840  244 WKAKHAIDTKNRSLKDALVMADVFLGLSVKDVLSENMLLSMNKDPIIFALANPDPEINPDIARKIRPDAIIATGRSDYNN 323
58578781  244 WKAKHAIDTKNRSLKDALVMADVFLGLSVKDVLSENMLLSMNKDPIIFALANPDPEINPDIARKIRPDAIIATGRSDYNN 323
73666751  244 WKEKHAIETKDRSLKDALVMADVFLGLSVKDVLSKDMLLSMNKDPVIFALANPDPEINPDIAREVRPDAIIATGRSDYNN 323
88607511  238 WKLKHAVETDARDLKDAIKGADIFIGLSVRDVLSREMLLSMNKDPVIFALANPYPEVNPEFAREVRGDAIIATGRSDYSN 317
88658354  244 WKEKHAIETENRSLKDALIMADVFLGLSVKDVLSKDMLLSMNRDPVIFALANPDPEINPNVAHEIRPDAIIATGRSDYNN 323
77165066  320 QVNNVLGFPFIFRGALDVRARAINEAMKVAAAQALAALAKEGVPESVCRAYGMERIEFGREYLIPKPFDPQVLLEVTTAV 399
254796783 317 QINNVMCFPYLFRGALDVGASKFNSEMKLAAVHAIAAIAKKPISMEVMDAYGDSHMQYSKEYILPKPFDKRLIAEIAPAV 396
269958273 318 QINNVMGFPYIFRGALDVRAKSVNNEMKLAAAEALAMLAREVVSDEVLEAYGGRGMGYGKEYIIPTPFDPRLLSVVSPAV 397
56416389  318 QINNVMGFPYIFRGALDVRAKSVNNEMKLAAAEALAMLAREVVSDEVLEAYGGRGMGYGKEYIIPTPFDPRLLSVVSPAV 397
57238851  324 QINNVMGFPYIFRGALDVQARCVNSAMKVAAANAIAMLAREYVSDEVSDAYGGRKMNYGKDYIIPTPFDPRLITVVAPAV 403
58616840  324 QINNVMGFPYIFRGALDVQARCVNSAMKVAAANAIAMLAREYVSDEVSDAYGGRKMNYGKDYIIPTPFDPRLITVVAPAV 403
58578781  324 QINNVMGFPYIFRGALDVQARCVNSAMKVAAANAIAMLAREYVSDEVSDAYGGRKMNYGKDYIIPTPFDPRLITVVAPAV 403
73666751  324 QINNVMGFPYIFRGALDVRAKSVNNEMKVAAANAIAMLAREYVSDEVSDAYGGRKMNYGKDYIIPTPFDPRLITIVSPAV 403
88607511  318 QINNVMGFPYIFRGALDVRAKRVNNEMKLAVAQAIAMLAREVVSDEVLEAYGGRGMRYGRDYIIPTPFDPRLISVVSPAV 397
88658354  324 QINNVMGFPYIFRGALDVRAKSVNNEMKIAAANAIAMLAREYVSDEVSDAYGGRKMNYGKDYIIPTPFDPRLITVVSPAV 403
77165066  400 AKAAGESGVARVPIRDFRAYREQLERRLGRSKEVMRQVINKA-RRrsqlstqhlesktspvekpvspGPLRIAFPEGDDK 478
254796783 397 ARAAVETGVAKKPIYDFDAYKDDLVRRLASGSTTLFGMVSSVlRD----------------------NGKRIIFAEGEEL 454
269958273 398 AKAAINSGVARKKIDDWDRYALELNSRISPTSNILNLMYGSV-KS----------------------SPKRVIFPEGEEV 454
56416389  398 AKAAINSGVARKKIDDWDRYALELNSRISPTSNILNLMYGSV-KS----------------------SPKRVIFPEGEEV 454
57238851  404 AKSAIESGVARRNIENWDEYVKQLESRLSSTSNVLNMMYSSV-KR----------------------DPKKVIFSEGEEE 460
58616840  404 AKSAIESGVARRNIENWDEYIKQLESRLSSTSNVLNMMYSSV-KR----------------------DPKKVIFSEGEEE 460
58578781  404 AKSAIESGVARRNIENWDEYVKQLESRLSSTSNVLNMMYSSV-KR----------------------DPKKVIFSEGEEE 460
73666751  404 ARAAIESGVARKKIEDWDEYTKQLASRLSSTSNILNMMYSAV-KR----------------------DPKRVIFSEGEEE 460
88607511  398 ARAAIETGVAQKGIDDWDKYARALGSRISPTSNVLNLIYGSV-KQ----------------------TPKRVIFSEGEEI 454
88658354  404 AKAAIDSGVARKNIENWDEYTKQLASRLSLTSNILSMMYSAV-KC----------------------DPKRVIFSEGEEE 460
77165066  479 RIIRAAARIVKEGIGKPVLLGKPDEIQALAKQLSVNLe-gIDLLDSQTHPQREDLAQQFFAMRARKGVTLAEARRYM-LR 556
254796783 455 KSIRAALQWRDMGYGTPILVGRNSVIEAKMDEMNLRNregFEVTNTAVSQRSGEYIEYMYGTLKRKGFPYERCVRDVeTN 534
269958273 455 RVIKAALQWYGQGYGTPILVGRVDKIKESLDLIGVDSlegITIANAAISSRNDVYIDYLYSKLQRMGRLHRSCVRDVkTD 534
56416389  455 RVIKAALQWYGQGYGTPILVGRVDKIKESLDLIGVDSlegITIANAAISSRNDVYIDYLYSKLQRMGRLHRSCVRDVkTD 534
57238851  461 KIIQAAVQWRNQGYGVPILVGRIDKVHEGFERLGIKDmkgIEIANAAISENNNKYTDYLYKQLQREGYLYRSCVRDVkTD 540
58616840  461 KIIQAAVQWRNQGYGVPVLVGRIDKVHEGFERLGIKDmkgIEIANAAISENNNKYTDYLYKQLQREGYLYRSCVRDVkTD 540
58578781  461 KIIQAAVQWRNQGYGVPILVGRIDKVHEGFERLGIKDmkgIEIANAAISENNNKYTDYLYKQLQREGYLYRSCVRDVkTD 540
73666751  461 KVIKAAVQWRNQGYGLPILVGRIDKVQEAFERLGIKNiqgIEIANAAVSKRNDEYTDYLYKKLQREGYLYRSCVRDVkTD 540
88607511  455 KVIKAALQWRSQGYGVPILVGRADKIKEGLERIGVDSldgIEIANAAVSTRNDVYIDYLYSKLQRKGYLHRRCVRDVkTD 534
88658354  461 KVIEAAVQWRNQEYGLPILVGRIDKVQEAFDRLGIKDtkgIEIANAAISQRNNEYTDYLYKKLQREGYLYRSCVRDVkTD 540
77165066  557 RHYYAPMLLLQGEVEAVVCGET-YHYPDSIRPALQILPLAKGISHASGLYMLLFKNRLIFCADTTVNITPDAETLAEIAL 635
254796783 535 NDVFAACMLALNDGDAVITGLTwSNAEDRLKSIVPIVGT---AGVVFEMSIIVADTGTFFYLQYW--------------- 596
269958273 535 RNVFAACMLACGDGDTLVTGIT-RGYSESLSDIRKVIDARGE---VFGLSVVVMEERTLFIADTAINELPTAQQLADIAI 610
56416389  535 RNVFAACMLACGDGDTLVTGIT-RGYSESLSDIRKVIDARGE---VFGLSVVVMEERTLFIADTAINELPTAQQLADIAI 610
57238851  541 RNVFAACMLACGDGDILITGLT-RGYTVSIHDVQKVIKPKGV---MFGLSIIVMKERTIFIADTAIHESPTPEQVAEIAI 616
58616840  541 RNVFAACMLACGDGDILITGLT-RGYTVSIHDVQKVIKPKGV---MFGLSIIVMKERTIFIADTAIHESPTPEQVAEIAI 616
58578781  541 RNVFAACMLACGDGDILITGLT-RGYTVSIHDVQKVIKPKGV---MFGLSIIVMKERTIFIADTAIHESPTPEQVAEIAI 616
73666751  541 RNVFAACMLACGDGDVLITGLT-RSYSASISDVQKVIGSQGV---VFGLSVIVMKERTIFVADTAIHESPTPEQIAQIAI 616
88607511  535 RNVFAACMLACGDGDILVTGVT-RGYRESLSDVSKVIGARSE---IMGLSVIVMEDRTLFIADTAINEFPTSKQMADIAV 610
88658354  541 RNVFAACMLACGDGDVLITGMT-RGYYASINDVQKVIGSQGV---VFGLSIIVMKERTIFVADTAIHESPTPEQIAEIAI 616
77165066  636 SAADTAHHFDIEPRVALLSFSNFGSVKHSLVDLVQAAVKILHRRRPDLVVDGEMQADTATNEDILSsTYPFSRL-KEDAN 714
254796783 597 ---------------------------------------------------------------------------H---- 597
269958273 611 KSAAAARSMGHEPRVAFVSFANFGSHSQKESDRVRQCMDIVASRNVDFEYDGEMSVDVALKPESLS-MYPFCRL-SKPAN 688
56416389  611 KSAAAARSMGHEPRVAFVSFANFGSHSQKESDRVRQCMDIVASRNVDFEYDGEMSVDVALKPESLS-MYPFCRL-SKPAN 688
57238851  617 QASMQARKMGHEPRVAFISSSNFGSHSQKDARRMRKAIEILDNCNVNFEYDGEMSIDVALNPELLT-LYPFCRL-TSSAN 694
58616840  617 QASMQARKMGHEPRVAFISSSNFGSHSQKDARRMRKAIEILDNCNVNFEYDGEMSIDVALNPELLT-LYPFCRL-TSSAN 694
58578781  617 QASMQARKMGHEPRVAFISSSNFGSHSQKDARRMRKAIEILDNCNVNFEYDGEMSIDVALNPELLT-LYPFCRL-TSSAN 694
73666751  617 QASIQARKMGHEPRVGFVSSSNFGSHCQEDARKMRKAVEILDSCNVDFEYDGEMSVDTALSSELLT-LYPFCRL-TGAAN 694
88607511  611 TAAAAAKKMGHEPRVAFVSCSNFGSHAQEGTERIRESIEILDRLGVGFEYDGEMSIDVALRKESLA-LYPFNRIkGGPAN 689
88658354  617 QASVQAKKMGYEPRVSFISSSNFGSHSQEDAKKMRQAIKILDSYNVSFEYDGEMSVDTALNPELLT-LYPFCKL-TGEAN 694
77165066  715 VLIFPDLTSGNIAYKLLVELGGAEAIGPILTGLSKPYHVLQRDASVDAIVNIAAIAAVQAQE 776
254796783     --------------------------------------------------------------    
269958273 689 VLIMPSLYSASISSKLLREVGGTTVVGPILMGMEKPVQIVQMTASVSEILNLAVLATLSHPI 750
56416389  689 VLIMPSLYSASISSKLLREVGGTTVVGPILMGMEKPVQIVQMTASVSEILNLAVLATLSHPI 750
57238851  695 VLIMPTLHSASISSKLLREATGVPVIGPILVGMEKPVQIVQMSSSVSEILNLTVLAPSINN- 755
58616840  695 VLIMPTLHSASISSKLLREATGVPVIGPILVGMEKPVQIVQMSSSVSEILNLTVLAPSINK- 755
58578781  695 VLIMPTLHSASISSKLLREATGVPVIGPILVGMEKPVQIVQMSSSVSEILNLTVLAPSINN- 755
73666751  695 ILVMPTLHSANISSKLLQQAVGVSVIGPVLIGMEKPVQIVQMSSSVSEILNLAVLAPSVNSN 756
88607511  690 VLIMPSLYSASISSKLLQEVGGVAVVGPILMGMEKPVQIVQMTASVSEILNLAVLSTLYNAL 751
88658354  695 VLVMPTLHSASISSKLLQRAAGVSVIGPILIGMEKPVQIVQMSSSVSEILNLTVLASLVNNT 756
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