Conserved Protein Domain Family
DD-carboxypeptidase_like
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cd14847: DD-carboxypeptidase_like 
Uncharacterized proteins of the MEROPS peptidase family M15, subfamily B
This family of uncharacterized proteins similar to D-Ala-D-Ala carboxypeptidase pdcA (Myxococcus-type) are zinc-binding enzymes that belong to the peptidase M15 subfamily B. The enzyme D-Ala-D-Ala carbozypeptidase catalyzes carboxypeptidation reactions involved in bacterial cell wall metabolism.
Links
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Statistics
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PSSM-Id: 350622
Aligned: 76 rows
Threshold Bit Score: 137.324
Created: 13-Jan-2014
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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active siteZn binding site
Feature 1: active site [active site], 5 residue positions
Conserved feature residue pattern:R H D [ED] HClick to see conserved feature residue pattern help
Evidence:
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                       #                                                
Q87MI5        26 MHPDVANDLLNMIEAAKKAGf--KMEIASGFRdFSRQRAIWNGKYegelpildsnsqplnkaalsdeeklkaILRWSALP 103 Vibrio parahaem...
Q8EZA8        55 VLEKLLELFQAYQRENPSEKq--KPFIVSAFRsFKDQKGIWEEKYsgkrkmresvk------gktpqeiislILEFSSAP 126 Leptospira inte...
WP_005469361  84 LQNVVADQFEAMSDAAAKDGi--SLKALSGTRtFSQQKGIWERKWavrkgsa--------------eerardILRYSSMP 147 Porphyromonas c...
WP_002775333  70 LRREALEAIQKMYAQIQKDLpgvPFWVQSGTRnFASQKSIWESKWngnvavggirln----tvkdpverarrILTYSSMP 145 Leptonema illini
XP_001020616  67 LHQDALHAFERMHIEAKKDNi--TLILISALRnFSYQKRIWQTKFqqlkngdpl---------ktdeqialeIMKYSAMP 135 Tetrahymena the...
WP_020571499  95 LHQDTYAGFEAMHAAAKADGv--KLVIVSATRnFKRQKQIWEAKWngqrllegkekad--evypepadraraILRYSSMP 170 Lewinella persica
WP_019386365  78 LNVEVYEAFVNMYNHAEKDGi--QLKIVSGTRnFAEQKAIWERKWekyqnln-------------pisrakkILEYSSMP 142 Flavobacteriace...
WP_022953299  69 MQNMAYDAFKAMHRDAELAGv--KLVIKSAARnFYQQKAIWEGKWdgkrsvggirniq--ktikdpvlrarkILEYSSMP 144 Leucothrix mucor
WP_002660435 113 IRKEAMAKFKEMRARAKEDGi--VLKIMSATRpFNVQKAIWERKWrgeqrvngkfvp----qdapkkakaeqILEWNSMP 186 Saprospira grandis
WP_002972856  69 KKALQQMVNDFEDSKPTTYKq--HIFLVSSFRnFGHQKGIWESKFtgkkvmrvpik------gkspeeitnlILEFSSAP 140 Leptospira terp...

Feature 1            #      #                                                            #  #    
Q87MI5       104 GGSRHHWGCDFDVYArnllppdtklqlepWEYLEGHq-lAFYCWLKDHIDEFGFFFPYl-----qDLGGVAiEPWHISHK 177 Vibrio parahaem...
Q8EZA8       127 GTSRHHWGTDVDLNAle-----------nSYFEKGGkgeKFYNWMFKNAKRFGFCQPYtpk-ssrGNKGYKeEKWHWSYA 194 Leptospira inte...
WP_005469361 148 MTSRHHWGTDIDINNl------------eNSYFASGkgkAEYEWLCRHGHEYGFAQVFtdk--gqGRPGYElEKWHWSYL 213 Porphyromonas c...
WP_002775333 146 GTSRHHWGTDFDINSl------------tVDYYRSGegkKLYQWMLVHAPKYGFCLVYte----gRKKGYEfEPWHWSFK 209 Leptonema illini
XP_001020616 136 TTSRHHWGTDMDINSv------------ePEYFESGqglIEYNWLKKNAKRFGFCQPYspkndgsRDRGYNlEQWHWSYM 203 Tetrahymena the...
WP_020571499 171 GTSRHHWGTDLDLNAl------------nNEHFKSGegkKVYDWLTANAATYGFCQPYtpk-gaeRPQGYEeERWHWSYL 237 Lewinella persica
WP_019386365 143 STSRHHWGTDIDLNSl------------nNSYFESGkgkKEYKWLVENANNYGFYQIYtek--ssGRTGYNlERWHWSYM 208 Flavobacteriace...
WP_022953299 145 GSSRHHWGTDIDLNSf------------nNSYFASGtgkRVYDWLVQNAPRYGFCQPYtak-selRPTGYNeEKWHWSFR 211 Leucothrix mucor
WP_002660435 187 STSRHHWGTDIDINNin-----------pAYWLKGQg-eKEYAWLLAHAAEFGFCQVYsa----gRPYGYQeEKWHWSYI 250 Saprospira grandis
WP_002972856 141 GTSRHHWGTDFDINAld-----------nAYFEENGkgkILYDWLKQNAHKYGFCQPYsrm-strNNKGYQeEKWHWSYA 208 Leptospira terp...

Feature 1                 
Q87MI5       178 AIGQQCAAQ 186 Vibrio parahaemolyticus
Q8EZA8       195 PISNKLQED 203 Leptospira interrogans
WP_005469361 214 PAAELYLEY 222 Porphyromonas catoniae
WP_002775333 210 PLSAPFVKD 218 Leptonema illini
XP_001020616 204 PISQQLLQY 212 Tetrahymena thermophila SB210
WP_020571499 238 PIATQLTDY 246 Lewinella persica
WP_019386365 209 PLSSKYLAF 217 Flavobacteriaceae bacterium P7-3-5
WP_022953299 212 PLSQQYTAQ 220 Leucothrix mucor
WP_002660435 251 PLAKEFTNQ 259 Saprospira grandis
WP_002972856 209 PISNQLTKE 217 Leptospira terpstrae

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