Conserved Protein Domain Family
rpoA

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CHL00013: rpoA 
RNA polymerase alpha subunit
Statistics
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PSSM-Id: 214333
Aligned: 129 rows
Threshold Bit Score: 272.607
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
115531994   3 NNKn-fADWDSLECKDLHNDLLYGRFALSPLTAKESRLLKKGLREALLTGILCLRF--THAKIQNACknLNLMNIVGIQE 79 
12545427    1 MTIt-nIK-----------------FFISKSKSKHPKKLKI------FHPV------------------NEFFDIEEIKE 38 
108773284   4 nvtddkIQWKCLESKIESQRIHYGRFAIAPLKKGQANTLGITLRRTLLSDLDGICI--TSVKIDNIK--HEYCTLTGVRE 79 
22711961    9 VLNq--PQWRCLESKIEKSTLHYGRFIISPLWKGQANTIGLALRRTLLSEVEGTCI--TSVKIKNAI--HEYSSLSGVQE 82 
115531992   2 SNPnngAEWQQVEADQLDSGLYYGRFALSPLTAKQASLLKKGLPEALLTEI--LCLrfTHAKIQNEC--VNLMNIVGIQE 77 
115531990  12 NNKn-fADWDYVECKYFHKDFAYGRFALSPLTAKESRLLKKGLFEALLTEILCLRF--THAKIQNEC--VNLMNIVGIQE 86 
115531956  12 NNKn-fADWDYVECKYFHKDFAYGRFALSPLTAKESRLLKKGLFEALLTEILCLRF--THAKIQNEC--VNLMNIVGIQE 86 
115531954   2 SNPnngAEWQQVEADQLDSGLYYGRFALSPLTAKQASLLKKGLPEALLTEI--LCLrfTHAKIQNEC--VNLMNIVGIQE 77 
226968665   8 SSAk----LECVEFRENNPRDHYARLVLGPLAPGQGVTLGNTFRRLLLNDLPGVAI--TAAKLNETR--TEFMTLPGIRE 79 
113170453   1 MIKa-aATLKSLQYRQNSLTDCYGRLSFGPVNPGQGLTIGNTLRRILLNDLPGIGV--IGAEINGVQ--SEFSTLPGIRE 75 
115531994  80 SLDEILKNFGKIILTGK---LeefvgkGPFVAILDV----------RG--PLNAMAVDIELP--PGIKVEIETQHI-ATI 141
12545427   39 NLSNICINLKKLRFKFNpknN------KEKKTFIIL----------NSfnKKSFSAKDIIIPstSNLKIVNLKEHLfNKI 102
108773284  80 SIQDILLNLKEIVFKGVc--D------KTQKGFIFV----------KG--PKKITASDIQIE--PCIEILDSNQII-AHL 136
22711961   83 SVHDILINLKKIILSSS---Fs-----GIFEGFLSV----------VG--PKTVLASDLNLP--SFIKIVNPDQYI-ATV 139
115531992  78 SLDEILKNFGKIILTGKl--Eefv-gkGPFVAILDV----------RG--PLNAMAVDIELP--PGIKVEIETQHI-ATI 139
115531990  87 SLDEILKNFGKIILTGK---LeefvgkGPFVAILDV----------RG--PLNAMAVDIELP--PGIKVEIETQHI-ATI 148
115531956  87 SLDEILKNFGKIILTGK---LeefvgkGPFVAILDV----------RG--PLNAMAVDIELP--PGIKVEIETQHI-ATI 148
115531954  78 SLDEILKNFGKIILTGKl--Eefv-gkGPFVAILDV----------RG--PLNAMAVDIELP--PGIKVEIETQHI-ATI 139
226968665  80 SVVEIFLNLRDIVFFNT---Fpd---vLAPQGTITIsprpqtdeskSFhtPRVICAGDMQLP--EGITCVDPTQPIaTLM 151
113170453  76 SVIEIFLNLRELIFTPTa--Tca---qKVKQTKPFVyakln-selkIDnfPYVVTAKDLHIP---EYEFVDPNQQI-ATI 145
115531994 142 TEPI---PFVVELRIE----L-------------------VSSTskg-etGIT--DEEGF-------------------S 173
12545427  103 SQKI---NLKVLIKIEnnenY----------------------------------------------------------- 120
108773284 137 TEPI---DFKVELTIEksmgF-------------------RLQNa-----TQI--SKDSF-------------------S 168
22711961  140 NKPI---NFNLQIYIQkgkgY-------------------SLKNp-----ISI--KQGFF-------------------L 171
115531992 140 TEPI---PFVVELKIElvssT-------------------SKG-------ETGitDEEGF-------------------S 171
115531990 149 TEPI---PFVVELRIE----L-------------------VSSTskg-etGIT--DEEGF-------------------S 180
115531956 149 TEPI---PFVVELRIE----L-------------------VSSTskg-etGIT--DEEGF-------------------S 180
115531954 140 TEPI---PFVVELKIElvssT-------------------SKG-------ETGitDEEGF-------------------S 171
226968665 152 NGDT---AFNLTFILEqstgY----------------------RvwkkptQSY--GTGFYpspqiesvqieqvksgvfqP 204
113170453 146 LSPTaaeNFKLTLLIGqgrgYqswkklpgvpqlmdqrffeQFDSt----qTNS--KSVTF-------------------P 200
115531994 174 IDPN-PPIQKVNSSIQG-YEYGGQTFQTLFIEILstsptvpnkalllvsmkimnlfqivlqakyldykelekgihvgvfc 251
12545427  121 ---FyNPIKRINFILEK----NNNIGKYIILDLN---------------------------------------------- 147
108773284 169 IDAIfMPIRNVNYSIHPvEKAGDWKSELLILEIW---------------------------------------------- 202
22711961  172 VDPVfIPIRSVNYSIHS-FEDEKATKEFLIVEVW---------------------------------------------- 204
115531992 172 IDPn-PPIQKVDTSIQC-YDYQGEPFQTLFLDIW---------------------------------------------- 203
115531990 181 IDPN-PPIRKVNSSIQG-YEYGGQTFERLSIEML---------------------------------------------- 212
115531956 181 IDPN-PPIRKVNSSIQG-YEYGGQTFERLSIEML---------------------------------------------- 212
115531954 172 IDPn-PPIQKVDTSIQC-YDYQGEPFQTLFLDIW---------------------------------------------- 203
226968665 205 IDGNfMPVKNVNFAVHE-VQPH---GEYIHFEIT---------------------------------------------- 234
113170453 201 IDAIfMPIRQVNFTVQE-HSVD---GEYIYFEVW---------------------------------------------- 230
115531994 252 vsalraeqskwiktiledalymvggrkhqgpltdeeddsidsnftpvqnldcriesyeeegqtfqrlfleiwTKSPTEPQ 331
12545427  148 ------------------------------------------------------------------------SDININP- 154
108773284 203 ------------------------------------------------------------------------TNGSITPK 210
22711961  205 ------------------------------------------------------------------------TNGSIEPK 212
115531992 204 ------------------------------------------------------------------------TDRTIHPH 211
115531990 213 ------------------------------------------------------------------------TSLPIIPN 220
115531956 213 ------------------------------------------------------------------------TSLPIIPN 220
115531954 204 ------------------------------------------------------------------------TDRTIHPH 211
226968665 235 ------------------------------------------------------------------------TNGSIHPH 242
113170453 231 ------------------------------------------------------------------------TNGSINPF 238
115531994 332 EALWEASAKILELFSLFLqTSKEnekdlkqiiKDwtENKRkhqev------lrllDSEESgsigwiTKMKLAYMhmtlls 405
12545427  155 -------------FKAFIes------------------------------------------------------------ 161
108773284 211 EAFHQASEKIMNIFLSLS-NSSDnqi----qeKS--TKNFeekeefifqnidgfkQDKETkvq-esLGWKKISI------ 276
22711961  213 EAIKEASYNLVNLFTPLV-SQEYqqlk--nqlFK--EDEKnkelnfi-etnsnaiSDNENs----yNLYNQIFL------ 276
115531992 212 EALAQASRKIFGLLSLVF-QAEYf--------QYneLENGlrygk------fclyPMTKEqfqwiqTALNEALAldmsge 276
115531990 221 EALLLGSMKIMNLFQIVL-QAKYld---------ykELEKgihvgv---fcvsalRAEQSkwi-ktILEDALYMvggrkh 286
115531956 221 EALLLGSMKIMNLFQIVL-QAKYld---------ykELEKgihvgv---fcvsalRAEQSkwi-ktILEDALYMvggrkh 286
115531954 212 EALAQASRKIFGLLSLVF-QAEYf--------QYneLENGlrygk------fclyPMTKEqfqwiqTALNEALAldmsge 276
226968665 243 NAFKHAGAILTEITRATL------------------QDPRpvvgid---eastpvDTAVAq----kAYFENIAI------ 291
113170453 239 DAVKSAAKVGMKLMTACLtt--------------lqDQQVyldeskl-petpnfvQVNYNkme-seSNFDQIFI------ 296
115531994 406 mnamyillvHRLKPDYDRYNSITD--QIVQELRASLNKlreiqkgeyseqrilvhsiaqeieaalqkyettyklddfvik 483
12545427  162 -----------------------------lkYLNLNNT------------------------------------------ 170
108773284 277 ---------NQLELSARAYNCLKN--EKISTLFDLLNY------------------------------------------ 303
22711961  277 ---------DQLELSSRAYNSLKK--NNINTISDLLKY------------------------------------------ 303
115531992 277 skhegpvtdEEGDSIDPTFTPVQKwdITMNS------------------------------------------------- 307
115531990 287 ---qgpltdEEDDSIDSNFTPVQNldCRIESYEEEGQT------------------------------------------ 321
115531956 287 ---qgpltdEEDDSIDSNFTPVQNldCRIESYEEEGQT------------------------------------------ 321
115531954 277 skhegpvtdEEGDSIDPTFTPVQKwdITMNS------------------------------------------------- 307
226968665 292 ---------EQLELSLRAYNCLKR--AQILTLADLSRE------------------------------------------ 318
113170453 297 ---------EQLELSLRAYNCLKR--ANILTLADLSQQ------------------------------------------ 323
115531994 484 akkdmitmiwdkeradlesslirweSDEDYLNL--------KKMNPVEMDRSFAELqyQETLRKEQDEQS 545
12545427      ----------------------------------------------------------------------    
108773284 304 -------------------------SQEDLLKI--------KNFGKRSFEQVVNAL--EKHFDMKLSKDS 338
22711961  304 -------------------------SYEDLLKI--------KNFGKKSADQVIEQL--KKRFKIQL---- 334
115531992 308 -----------------------------------------YQYSGETFQGLLSRF-------------- 322
115531990 322 -------------------------FQRLFLEIwtksptepQEALWEASAKILELF--SLFLQTSKENEK 364
115531956 322 -------------------------FQRLFLEIwtksptepQEALWEASAKILELF--SLFLQTSKENEK 364
115531954 308 -----------------------------------------YQYSGETFQGLLSRF-------------- 322
226968665 319 -------------------------SYSSLLAL--------RNFGQKSAEEVAKAL---ETYGIELVQEP 352
113170453 324 -------------------------SFRDLMKL--------RNFGQKSADEVRAAL---STYGIELKED- 356
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