1MTZ


Conserved Protein Domain Family
pro_imino_pep_2

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TIGR01250: pro_imino_pep_2 
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proline-specific peptidase, Bacillus coagulans-type subfamily
This model describes a subfamily of the alpha/beta fold family of hydrolases. Characterized members include prolinases (Pro-Xaa dipeptidase, EC 3.4.13.8), prolyl aminopeptidases (EC 3.4.11.5), and a leucyl aminopeptidase
Statistics
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PSSM-Id: 188121
Aligned: 9 rows
Threshold Bit Score: 402.914
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1MTZ_A         4 ECIENYAKVNGIYIYYKLCKAPEeKAKLMTMHGGPGMSHDYLLSLRDMTKE---GITVLFYDQFGCGRSEEPDQSK---- 76  Thermoplasma ac...
CAA06029       2 KQGTTILTLDNGYHLWTNTQGEG-DIHLLCLHGGPGGTHEYWENFGEELADl--GVQVHMYDQLGSFYSDQPDYSDpeia 78  Lactobacillus r...
CAA84382       2 DQ-TRIVTLDNGYHLFTRKVNEG-PVKLLCVHGGPGDNHEDFDNFKAGLAGk--GVEVYSYDQLGSYWSDQPDFSKeen- 76  Lactobacillus d...
BAA19688       2 IP---ITTPVGNFKVWTKRFGTNpKIKVLLLHGGPAMTHEYMECFETFFQRe--GFEFYEYDQLGSYYSDQP--TDek-- 72  Elizabethkingia...
P96084         4 ECIENYAKVNGIYIYYKLCKAPEeKAKLMTMHGGPGMSHDYLLSLRDMTKE---GITVLFYDQFGCGRSEEPDQSK---- 76  Thermoplasma ac...
P52278         2 EIIEGKMPFMGYETYYRIVGERSeKPPLVLLHGGPGSSHNYFEVLDELAQKd--GRRIIMYDQLGCGESSIPDDHPe--- 76  Lactobacillus h...
WP_003914639  13 GQVEGTIAVPGGRVWFQRIGG-GpGRPLLVVHGGPGLPHNYLAPLRRLSDE----REVIFWDQLGCGNSACP--SDvd-- 83  Mycobacterium t...
P46541         1 mYTEGFIDVTGGRVSFQKFDENGgGTPVIVLHGGPGSSCYSLLGLKALAKD----RPVILYDQLGCGKSDRPMDTt---- 72  Bacillus coagulans
AAA19050       2 KTGTKIITLDNGYHLWTNTQGEG-DIHLLALHGGPGGNHEYWEDTAEQLKKqglNVQVTMYDQLGSLYSDQPDYSDpeia 80  Lactobacillus h...
1MTZ_A        77 ---FTIDYGVEEAEALRSKLFGNeK--VFLMGSSYGGALALAYAVKY-QDHLKGLIVSGGLSSVPLTVKEMNRLI-DELP 149 Thermoplasma ac...
CAA06029      79 kkyLTTDYFLGEVEEVRKKLGLD-H--FYLIGQSWGGALTQLYALKY-GQHLKGAIISSMVDNINEYVEHINLVReEALP 154 Lactobacillus r...
CAA84382      77 rkyLTVDYFVDELEEVRQKLGLE-N--FYLLGHSWGGLLAQEYAVRY-GQHLKAVVIESMIDNLDEYTVNINRERdEMFS 152 Lactobacillus d...
BAA19688      73 --lWNIDRFVDEVEQVRKAIHAD-KenFYVLGNSWGGILAMEYALKY-QQNLKGLIVANMMASAPEYVKYAEVLS-KQMK 147 Elizabethkingia...
P96084        77 ---FTIDYGVEEAEALRSKLFGN-Ek-VFLMGSSYGGALALAYAVKY-QDHLKGLIVSGGLSSVPLTVKEMNRLI-DELP 149 Thermoplasma ac...
P52278        77 --lYTKETWVKELEALREHLALR-K--MHLLGQSWGGMLAIIYMCDYhPEGIQSLILSSTLSSASLWSKELHRMI-KYLP 150 Lactobacillus h...
WP_003914639  84 --lWTMNRSVAEMATVAEALALT-R--FHIFSHSWGGMLAQQYVLDK-APDAVSLTIANSTASIPEFSASLVSLK-SCLD 156 Mycobacterium t...
P46541        73 --lWRLDRFVEELAQIRQALNLD-E--VHILGHSWGTTLAAAYCLTK-PSGVKSVIFSSPCLSAPLWEQDQKRNL-KKLP 145 Bacillus coagulans
AAA19050      81 kkyLTYEYFLDEVDEVREKLGLD-N--FYLIGQSWGGLLVQEYAVKY-GQHLKGAIISSMVDEIDEYVASVNRRRqEVLP 156 Lactobacillus h...
1MTZ_A       150 AKYRDAIKKYGSSGSYENPEYQEAVNYFYhqhLLRSEDWPPEVLKSLEYAE-RRNVYRIMNGPNEFTITG--TIKDWDIT 226 Thermoplasma ac...
CAA06029     155 PSAVKYMKKIEKAGDWDDPQYQKYVDVLN---RGYVDRKQPPAISHLISTM-ATPVYNAFQGDNEFVVTG--KLKDWDIS 228 Lactobacillus r...
CAA84382     153 PAQVEYMKECEASENFDDAMYQELVAKLY---SVYLVRHPENATRHVVSTT-NTQVYNYFQGNNEFMMVG--KLTEWDFR 226 Lactobacillus d...
BAA19688     148 PEVLAEVRAIEAKKDYANPRYTELLFPNYyaqHICRLKEWPDALNRSLKHV-NSTVYTLMQGPSELGMSSdaRLAKWDIK 226 Elizabethkingia...
P96084       150 AKYRDAIKKYGSSGSYENPEYQEAVNYFYhqhLLRSEDWPPEVLKSLEYAE-RRNVYRIMNGPNEFTITG--TIKDWDIT 226 Thermoplasma ac...
P52278       151 IEEQAAIHRAELTGNFNDPDYLKANEHFMnqhAIDMTKTWPECVMRKKRGG-T-VAYETAWGPNEYTPEG--NLHDYEYT 226 Lactobacillus h...
WP_003914639 157 VATRSAIDRHEAAGTTHSAEYQAAIRTWNe-tYLCRTRPWPRELTEAFANM-GTEIFETMFGPSDFRIVG--NVRDWDVV 232 Mycobacterium t...
P46541       146 LDVQETINRCEENGTTDSEEFAAAIEVFGk-hFVNRLEKQPEWLEQKPSGYrNADIYNIMWGPSEFTVLG--NLKNFDCT 222 Bacillus coagulans
AAA19050     157 QTEIDFMHECEKNNDYDNQRYQDDVQILN---INFVDRKQPSKLYHLKDIG-GSAVYHAFQGDNEFVITG--KLKDWHFR 230 Lactobacillus h...
1MTZ_A       227 DKISAIKIPTLITVGEYDEVTPNVARVIHEKIAGSELHVFRDCSHLTMWEDREGYNKLLSDFIL 290 Thermoplasma acidophilum
CAA06029     229 DQIHNIKVPTLLTFGEHETMPLKAAQRMAEVIPHARLVTTPNGGHHHMIDNAPVYFKHLKQFIS 292 Lactobacillus rhamnosus
CAA84382     227 DKLAQITLPTLLTVGEFDTMPLDAVRRMHHSLKNSRMVVTPDGATATMLTT-QMHFS--LPYIs 287 Lactobacillus delbrueckii
BAA19688     227 NRLHEIATPTLMIGARYDTMDPKAMEEQSKLVQKGRYLYCPNGSHLAMWDDQKVFMDGVIkfik 290 Elizabethkingia meningoseptica
P96084       227 DKISAIKIPTLITVGEYDEVTPNVARVIHEKIAGSELHVFRDCSHLTMWEDREGYNKLLSDFIL 290 Thermoplasma acidophilum DSM 1728
P52278       227 DKLSKIKVPTLITSGTDDLCTPYVAKTMQDQIASSKWRLFEGCGHMSFVEKTDEYVALLQEWLD 290 Lactobacillus helveticus
WP_003914639 233 DRLADIAVPTLLVVGRFDECSPEHMREMQGRIAGSRLEFFESSSHMPFIEEPARFDRVMREFLR 296 Mycobacterium tuberculosis
P46541       223 TQLKEITCPSLYTCGRFDEATPETTEYYSSLTPKSKFHVFEKSAHMPYIEEPEEYLAVIGDFLN 286 Bacillus coagulans
AAA19050     231 DQLKNIKVPTLLTFGENETMPISTAKIMQKEIPNSRLVTTPDGGHHHMVDNPDVYYKHLADFIR 294 Lactobacillus helveticus CNRZ32
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