3NK3


Conserved Protein Domain Family
ZP

?
smart00241: ZP 
Click on image for an interactive view with Cn3D
Zona pellucida (ZP) domain
ZP proteins are responsible for sperm-adhesion fo the zona pellucida. ZP domains are also present in multidomain transmembrane proteins such as glycoprotein GP2, uromodulin and TGF-beta receptor type III (betaglycan).
Statistics
?
PSSM-Id: 214579
Aligned: 43 rows
Threshold Bit Score: 164.097
Created: 13-Jul-2011
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
3NK3_A          7 QCQEAQLVVTVHRDLFGTGrlINAADLTLgP----AACKHs--sL-NAAHNTVTFAAGLH--E--CGSVVQ-VTPDTLIY 74   chicken
AAC28564      454 KCDNEKMVVAVDKDSFQTNg-YSGMELTLlD----PSCKA------KMNGTHFVLESPLN--G--CGTRHRrSAPDGVVY 518  house mouse
AAC59876       56 QCSNT-MILSMPKCQMEKDr-YNSTNLHLvD----SACQLkdqiV-D-DLAQMVYNWTLKngE--CGNNLI-VNSTHVTY 124  African clawe...
NP_001081431   37 KCDNDQMKITLLSSVLDELd-INASQLHMnN----PLCNMq--nTsGLYLSIVLTHENHT--F--CGTAVQ-VNGSHLIY 104  African clawe...
EDL17691     1243 lCQSNHMQASVSRSYLQSMg-YSARDLVIpGwnssYHCQP------QITQREVIFTIPYT--G--CGTIKQ-ADNETINY 1310 house mouse
AAD55939      276 SCASDKMRVIISKSYLQSLn-YHESNLQLnD----PTCRP-------SVSNVVEFSIPLH--E--CGTIKK-IEDHTISY 338  Norway rat
NP_001080952  126 TCLPNIMVISVSQCLLTHLg-FDYTNMHLlNnd-sDICNIhypeI-INNNRVESMQLKVQsgW--CGNKMT-FDSSKLYY 199  African clawe...
AAA90990      592 HCNSNYMELLIPLSEISSRg-LSVYDIRLqD----PSCHAt------AYGQYARLYGPLN--G--CGSRTE-TSGDTIIY 655  sea lamprey
NP_989670     446 KCDDKVMTVAVEKDSLQASg-YTRTELSLlD----HSCKA------RMNGTHFILESLPN--K--CGTRTS-YILDKIVY 509  chicken
XP_003208219   31 yCYPRTIITKIPECPYGW----EVNQLALgG-----ICYNgihdS-GYYQFTIPDLSPKN--KsyCGTQSE-FKNPVYHF 97   turkey
3NK3_A         75 RTLIN-YDp-----------------------------SPasNPV--------IIRTNPaVIPIECHYPRREQVSSNAIR 116  chicken
AAC28564      519 YNSIV-VQapspgdssgwpdgyedlesgdngfpgdtdeGE--TAP--------LSRAGV--VVFNCSLRQLRs--PSGFQ 583  house mouse
AAC59876      125 ANKLF-VYa------------------------------Q--NTL--------ITSRNNaTLYFSCSYPLNMKTSLNFPL 163  African clawe...
NP_001081431  105 SNELT-SGtsfv----------------------nqpvGP--GSL--------ITRSSDiRIHFSCVYKYDGVVSLPYPL 151  African clawe...
EDL17691     1311 SNFLR--Av-----------------------------VS--NGI--------IKRRKDlNIHVSCKMLQNTWVNTMYIT 1349 house mouse
AAD55939      339 TNIITfTQs-----------------------------PE--SAV--------ITRKRHlQIVVTCEMEYNS-TVEILYI 378  Norway rat
NP_001080952  200 KNSLY-IGi-----------------------------QN--KSV--------IT-VDPmTLNFTCSYNMTMQTSLIYAL 238  African clawe...
AAA90990      656 MNTAY-GYv-----------------------------SP--NG------------AKRlRVPMFCYMGSSGRA--MATF 689  sea lamprey
NP_989670     510 FNSIV-IQlsspaegss-------------fddddmesGD--NGFpgdadegdVTFSNWpEIAFNCTLHQPEKDFFNPAM 573  chicken
XP_003208219   98 YNSIV-SN-------------------------------D--STV--------IVKSQPvNYSFTCTYNANYLVNQAAFD 135  turkey
3NK3_A        117 PTWSp-FNSALSa--EERL--VFSLRLMSDD-WSTERPFTGf----qLGDILNIQAEVSTEN---HVPLRLFVDSCVAAL 183  chicken
AAC28564      584 DQl------------DGNA--TFNMELYNtDlFLVPSPGVFsv---aENEHVYVEVSVTKA----DQDLGFAIQTCFISP 642  house mouse
AAC59876      164 KTVFgsTEISVPn-gEGKL--TVIMSVFTdSaFSQHVTADS--------ELIVEQPLYVSVLmasLESFSVKVTNIYVTE 232  African clawe...
NP_001081431  152 LTSFs-SVTFVVk--EGIF--NVTMTSYPTSeFKQPYEWLPvi---pLSQNLNVQLQVHEHDl--DNYFSLRIEDCWATP 221  African clawe...
EDL17691     1350 NNt---VEIQEVq--YGNF--DVNISFYTSSsFLFPVTSSPyy--vdLDQNLYLQAEILHS----DASLALFVDTCVASP 1416 house mouse
AAD55939      379 TEDDv-IQNQSV---LGKY--NTSMALYESGsFENLIQESPyy--vdLNQTLFVQATLHTS----DPSLVVFLDTCRASP 446  Norway rat
NP_001080952  239 KPVLs-TVSISGpngTGSY--ALTMSAYNNPdYTSPIQAEDtv---eVGTYIYLGLFVKDAD---GAAFTLRVEECYATP 309  African clawe...
AAA90990      690 TPRVq-DEVSM-----GLF--DLRVRFYMNQfFHQPIYSYPyd--veLGEPLYAEVALTSAA----RDLQLFLETCKVSP 755  sea lamprey
NP_989670     574 FWPPe-PHITNV---------TFNMELYKTDlFLAPSQGLFsv---aENGPIYVEVSVTKA----DISLGFAIQTCFVSP 636  chicken
XP_003208219  136 QRVAt-VHVKNGs--SGSFesQLSLNFYSNAkFSSIKEAPFvvetseIGSDIFAGVEAKG-L---SDRFKVVLNNCWATP 208  turkey
3NK3_A        184 SPdgdsSPHYAIIDfNGCLVDGRVDdtSSafiTPRp----rED----VLRFRIDVFRFAgdN-----R-----NLIYITC 245  chicken
AAC28564      643 YSnpdrMSDYTIIE-NICPKD---DsvKF---YSSkrvhfpIP----HAEVDKKRFSFV--FksvfnT-----SLLFLHC 704  house mouse
AAC59876      233 TSdssvEPKLYLLQ-NGCKPDgVGAdlMS---TLQng---nNT----ESRFIMKVFKFS--A-----T-----SSLYLFA 289  African clawe...
NP_001081431  222 TAnpedKIRYPIIS-SGYPND---TtvAM---IQTl----dNS----LTRFVMQMFHFI--N-----Y-----SEVYLHC 274  African clawe...
EDL17691     1417 HPndfsSLTYDLIR-SGCVRD---DtyQS---YSSp----sPR----VSRFKFSSFHFL--N-----Rf----PSVYLQC 1470 house mouse
AAD55939      447 TSdf-aSPTYDLIS-SGCSRDEt----CE---VYPl----fGH----YGRFQFNAFKFL--R-----Hl----SSVYLKC 498  Norway rat
NP_001080952  310 TSdpsdINKVYIVR-GGCAYTNDVDswVE---QNGk----aL-----EARIKLSTFSFQ--S-----Q-----TNVYIFC 364  African clawe...
AAA90990      756 YPgapdSASFFLLQ-NGCRVDPs---ySD---YNSg----vND----RRRFSFDSVEFF--V-----G-----AQVYLEC 808  sea lamprey
NP_989670     637 FSnpdrMSDYTIIE-NICPKD---EsvKF---YSTe----kLNfpiaHAQKDKKRFSFV--F-----KpifniSLLFLHC 698  chicken
XP_003208219  209 SSeyfyQVHWPLIT-KGCASD---FsiVV---HENg----kTN----RATFQFNAFRFQ--N-----Ipk--lSKVWLHC 264  turkey
3NK3_A        246 HLKVTPADQGp----DPQn--KACSFN 266  chicken
AAC28564      705 ELTLCSRNKGsqklpKCVtpdDACTSL 731  house mouse
AAC59876      290 DVTICNG--------TCI---PDCSSR 305  African clawed frog
NP_001081431  275 KVLLCQPNSTv----FCNr--Pdpyvg 295  African clawed frog
EDL17691     1471 KLVVCRAYDTs----SRCy--RGCVVR 1491 house mouse
AAD55939      499 KILICDTSDHt----SRCn--QGCVSR 519  Norway rat
NP_001080952  365 NAMLCPNTTNs----QCDkcktarass 387  African clawed frog
AAA90990      809 SVRVCNVSDWg----SRCr--RGClrg 829  sea lamprey
NP_989670     699 ELTLCTNIDKd----TQRl--PKCVPp 719  chicken
XP_003208219  265 ETHVCDSEKFs-----CP---VTCDKR 283  turkey
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap