Conserved Protein Domain Family
PIRT
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pfam15099: PIRT (this model, PSSM-Id:405740 is obsolete and has been replaced by 434456)
Phosphoinositide-interacting protein family
The function of this family, PIRT, is not known, however it is predicted to be a multi-pass membrane protein. This family of proteins is thought to have a role in positively regulating TRPV1 channel activity via phosphatidylinositol 4,5-bisphosphate (PIP2). This family of proteins is found in eukaryotes. Proteins in this family are located in the cell membrane. Proteins in this family are approximately 140 amino acids in length.
Links
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Statistics
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PSSM-Id: 405740
Aligned: 5 rows
Threshold Bit Score: 165.465
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_007483056   5 PSALNADEKSPESKDLLPSQTASSLCISSRSESVWTAGSKNNWEIFRKPIIIMSTGGAIFLFGVVITCLsy--------- 75  gray short-tail...
XP_002186907   5 PKSPEESEKSPQLRELITSDTGSTLCTSSRSESVWTSAPRSKWDIYHKPVVVVSVGAAVFLFGVVITSL----------- 73  zebra finch
XP_019477143 135 PPSPNGSLKSPPSKELLTSNTASTLCISSRSESVWTNTSRSKWDIYHKPIIVMSVGAAVFLFGTVITTL----------- 203 turkey
XP_004918463  17 RSS------SSESKDLVTSRTESTLYSSSRSESLWTNGPRSAWDVYQKPIIIMSIGGSIFLLGIILTTIyfmsfdgkrlp 90  tropical clawed...
XP_008102471   7 ENQ-EDGEKSPESKDLLTSQTASTLCISSRSESGWSTPPLNKWDVYHKPVIVLSVGGAVFLFGVAITSLtcltvdkniti 85  green anole

XP_007483056  76 --tLNLPQNSTVHFgyQMSGPAFLSLGLMLLVCGLVWVPIIKKKLKQRQKSIFFQSLKSFFLNR 137 gray short-tailed opossum
XP_002186907  74 ---SCFLTKNKKVY--KMSGPAFLSLGLMLLVCGLVWIPIIRKKQKQRQKSQFLQSLKSFFFNR 132 zebra finch
XP_019477143 204 ---SCFEIKNNEVY--KMCGPAFLSMGLMLLVCGLVWIPIIRKKQKQRQKSQFLQSLRSFFFNR 262 turkey
XP_004918463  91 srnDTSPNPDAPIS--KIFGPVAFSIGLMVLIFGLVWVPIIKKKRKRSVSRLFGYKQTSFFhfs 152 tropical clawed frog
XP_008102471  86 annTITKNTTKEVF--KLCGPAFLSLGLMLLVCGLVWIPIIRKKLRQKQKYHILQSIKSFFLNR 147 green anole
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