Conserved Protein Domain Family
LIN37

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pfam15306: LIN37 (this model, PSSM-Id:405894 is obsolete and has been replaced by 464632)
LIN37
LIN37 is a component of the DREAM (or LINC) complex which represses cell cycle-dependent genes in quiescent cells and plays a role in the cell cycle-dependent activation of G2/M genes.
Statistics
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PSSM-Id: 405894
Aligned: 34 rows
Threshold Bit Score: 94.3915
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q16GT0        64 SVGLRHQQGSS------FIMKLFDRSVDL--AQFDGESSLYPVCRAWMRNQPRarqnpyd-pkpsdpASPPRGAESSRHS 134 yellow fever mo...
EGT52158     111 STSLMDSPRKTmtrdskIMFELRGKPFEMvaGRFEEE---YSLGRAWVKGHMNseyep-----irtqRTEFASNLAVEYL 182 Caenorhabditis ...
3_pfamImport   1 SNSLMDSPRKTmnrdskIMFELRGKPFEMvaGRYEEE---YSLGRAWVKGQMNteydp-----iktkRTEFAPNLAVDYL 72 
EFO90216     112 STSLLDSPRKTmtrdskIMFELRGKPFEMvaGRFEEE---YSLGRAWVKGHMNndyvp-----intkRTEFAPNLAVDYL 183 Caenorhabditis ...
Q23482       112 STSLMESPRKTmtrdskIMFELRGKPFEMiaGRFEEE---YSLGRAWVKGHMNneyep-----ikaqRTDYAPNLAVDYL 183 Caenorhabditis ...
XP_001750304  55 QSPAQQRYSKAp-----HIMTLFDKDINL--AAVSPTTALYSAARSWMYMDTSgywlrrrrapvaqdATA---------- 117 Monosiga brevic...
XP_001988537 129 EASPSSSRPDS-------VMPWFERRLDQ--SQHGNERSLYSMSRDWVSNLPLnasastkknsnsngDSSIPMVMPEHED 199 Drosophila grim...
Q7K159       107 aavAQKAPGET------YVMRLFERSLDL--SKYQDKTPLYPICRAWMANQPKnpav-------gafQTDASLTATKRED 171 fruit fly
Q174J5        58 SSESIPIPHQS------YIMKLFDRSVDL--ARFDETTPLYPICRAWMQNQPRvn-----------pKQLRTPSPVKREH 118 yellow fever mo...
XP_001849685  59 SAAIRHQHSST------FIMKLFDRSVDL--ARFPEATALYPVCRAWMQNTPRva----------rrDEVVEGVPEPREL 120 southern house ...
Q16GT0       135 MPDIVer-fNRKEVLEIPDMPKPSETELE-----PF---------RFERHFAEGEDNepdldgvegsadrKEILLQHHKA 199 yellow fever mo...
EGT52158     183 ACREI------------YKMPRPDKSlp----elPV---------RPPRQDKFDRNVdp---------rfFTDLKNEHVR 228 Caenorhabditis ...
3_pfamImport  73 SCREI------------HRMPRPDNTvp----dfAV---------CPEPTDEFDADVdp---------ryLTNLKNEYVR 118
EFO90216     184 ACREI------------HRMPRPDENvp----elPV---------IPTKIDKFDDQVdp---------ryLSDLKTEYIR 229 Caenorhabditis ...
Q23482       184 ACREI------------HRMPRPDKSip----elPI---------VPSRIDEFDATVdp---------ryETDLKNEYIR 229 Caenorhabditis ...
XP_001750304 118 -----------------FDLPSPTLPLEPap-alALefwpnafdqAANRLPETRSNIdqalvtqdariepLKTIGSARVD 179 Monosiga brevic...
XP_001988537 200 DAEKVlaqqRSGELKVLKHMPKARETDMLpipipLP---------V-----TQNWDLeg---------asKQQLLADNMK 256 Drosophila grim...
Q7K159       172 NGEEIlsqiKSGEIKVINQLPQAKSTDLPiipprLE---------FSQEDKKREKALqg---------asTSDLLSSNMN 233 fruit fly
Q174J5       119 NPQMVdq-yRNGELKEIRSMPRPDADLVErcplpLP---------SQTRTSKELLDVep---------msKATLLAEHKN 179 yellow fever mo...
XP_001849685 121 QVDVLer-yNRKELDQIEKMPGPAESELEaf-------------vREERFAERGEEMgtgee----evlgREELLKGHKA 182 southern house ...
Q16GT0       200 ---RWTKMRRSWQGHRQNY-------L-RKYQLSYDLLD 227 yellow fever mosquito
EGT52158     229 ---HWKEVKKEWCAHQRRR-------D-ARYSRSIALIE 256 Caenorhabditis brenneri
3_pfamImport 119 ---HWKAVKREWCSHARLR-------T-ARNARSIELIQ 146
EFO90216     230 ---HWKEVKKGWCAHQRDR-------N-ARYAKSIQLIE 257 Caenorhabditis remanei
Q23482       230 ---HWKQVKKGWCAHQRRR-------T-APHARSIALIN 257 Caenorhabditis elegans
XP_001750304 180 gryQLRQMKEHWVNRHRARcldyncrRsSIYAASVRVIQ 218 Monosiga brevicollis MX1
XP_001988537 257 ---RWKRVRNHWQKHNQEY-------EhARYETIDQILK 285 Drosophila grimshawi
Q7K159       234 ---RWKKVRGHWIKHIKKY-------EkERYEVIDKIMs 262 fruit fly
Q174J5       180 ---RWTQIRHNWEQHGRIR-------N-QRHVASFELLD 207 yellow fever mosquito
XP_001849685 183 ---RWSGIKRRWVGHRRNY-------L-GKYQQSFDLLD 210 southern house mosquito
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