1XUU,1VLI


Conserved Protein Domain Family
SpsE

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COG2089: SpsE 
Sialic acid synthase SpsE, contains C-terminal SAF domain [Cell wall/membrane/envelope biogenesis]
Statistics
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PSSM-Id: 441692
Aligned: 366 rows
Threshold Bit Score: 260.801
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1XUU_A        18 HEPLIICEIGINHEGSLKTAFEMVDAAYNAGAE------VVKHQTHI---VEDEMSDEAKQVIPG------N-----ADV 77 
ALP52643      15 RPPVVLPDIGTFFNQDVALAARMVAAVKAAGAR------YVKGEVLH---DAEICLKTDVAEHYL------GadaqsvGE 79 
CUR50917      15 HPTFVIVEMAWGHDGSVDKAKKIIDHAADAKVD------AINFHITS---MPDYMVRNYTAGVGK------Sss-tsNTK 78 
CUR50975      15 NPCFISFEPGATY-ANLEQAKMMTHATSLAKAD------GIKFQTLAtgdADRLMGIKDIKINFG------Tan-gkKEE 80 
YP_094804     16 HPPIFLAEIGTFFNQDLGIAEQLLHKIITIRDKvpyqplILKTEILN---NPNICLPVDYEETYT------SksgevRKE 86 
WP_083800256  36 SPLFIIAETGVTCNYDLNIAKELIDVVAESDAD------AIKFIFWF---PEEIMSDKTITYSYD------Sle-gpKTE 99 
WP_013817853   4 SKVYIIAEVAQAHDGSLGILHSYIDAVADTGAD------AIKFQMHI---ADAESSPFEPFRVAFs----------yQDH 64 
WP_015229809  14 YPCFITFEAGATHSG-VEYAKKLVQLAAQAGAD------AVKFQIYD---VDRLVSDKKQLFSYKvlvdreSgnteevQE 83 
WP_015404652  16 AKTFIIAEVAQNHDGSLGTAHAYIDAVAKTGAD------AIKFQTHI---ASEESTLDEPFRVKFs----------fQDA 76 
WP_126464012  13 APCYITFEAGPTHQG-LESAKRLATLAAEAGAD------GIKFQIFD---PDRLIADKDLSYSYEvlldklTgktemvTE 82 
1XUU_A        78 SIYEIMERCALNEEDEIKLKEYVESKGMIFISTPFSRAAALRLQRMdIPAYKIGSGECNNYPLIKLVASFGKPIILSTGM 157
ALP52643      80 NYRQLVERKALPLSQYEKIFAPCRELKLGLVLSVYDLKGADFAKRLgACALKIASTNVVHAPLIRYCAGLDLPLIIDTGK 159
CUR50917      79 PLFDYLEQINLSQDDWKILIPYAKSKGLLVSALCNDIPSEKFVSTLaPDLYALHPSCMAEEELIKKIAKNGKPVILNVGG 158
CUR50975      81 LVYDALKRRELPKESWRELVKYSHDLNLVFITTPEFPESIEFLVDAgVDALKISKGDINNVLLIEEAAKTNIPIILD-GR 159
YP_094804     87 NYRSLIERKVLPLEHYSMLFSLLKNANLPFIVSIYELDTIDFAIKQgACALKTSSSNIVHVPLIRHLAKTGLPLIIDTGR 166
WP_083800256 100 NMFAMLNQLRFSLDEWRELKAYGDKRKVIIFSTVNSPSGIEYAETLgLEAYKLSSWDYNYLPLWRRIAALKKPVIIDTGP 179
WP_013817853  65 TRYDYWKRMEFTQEQWVGIKKHCEEVGLEFLVSPFSVAAVRMLESLgVKRYKIGSGEVRNYLMLEHIALTGKDILISTGM 144
WP_015229809  84 PLYDILLRRSLTQNEWKEVKATADQEGLAFFATVGFPEDIELLQELkCDSIKIASADVNHHPLIRQAAKTGMCIQLDTGN 163
WP_015404652  77 TRYAYWKRMEFTSEQWQGLAGHAKDAGLVFLSSPFSEKAVRILSSIgMPAWKVGSGEVFNKDIIRAMARNKAPILLSTGM 156
WP_126464012  83 PLRDIFIRRAMTDAEWAELRAHCGKLGIGFIATIGDEVGLALARQLnCHSLKIASADINHTPFLRLAARTGISLQLDTGS 162
1XUU_A       158 NSIESIKKSVEIIREAGV--PYALLHCTNIYPTPYEDVRLGGMNDLSEAFpDAIIGLSDHTLD-----NYACLGAVALGG 230
ALP52643     160 ATLDEALRAVNWARRAGAe-RIVLEYSPPAPPAPVARHNLRVFNRLAELF-NGPLGLSDHHAG-----EEMLYAATALGC 232
CUR50917     159 CSIGEIDRAIGWIRESGNs-DICLLYGIQTYPTSIENAKIGYIKTLQNTF-GLPAGMADHTDGdselaLIVPIAGIVAGS 236
CUR50975     160 EKFHDVEVAMKICEKNGNd-QIIIMHCPSGYPTENAGVHLRAINAIQEKC-QYPVGFADHSPG-----DIMNFAAVAMGA 232
YP_094804    167 SSLTDICKAVETAKSAGCe-KIIIEHSPDGHPALPEAHNLRMLRTLNQCF-SLPVGLSDHYNG-----IEMLYMSIALGA 239
WP_083800256 180 VKLAEMAKVMQLMLEAQNd-QCILLHCTSA--DSLAEKNMGTIPYLRDTF-HALVGYSSRDCH-----DETDIMAVALGA 250
WP_013817853 145 SGFTEIEQALAFLDECKAsqERVIFQCTTAYPTPPEQIGLNVLPELQNRF-NLPIGLSDHSGT-----IFAPLAAVTLGA 218
WP_015229809 164 STIGEIEEAVDLVLQEGNd-NLIIHQCPSGYPARLESINLNIIPTLKQMF-QVPIAYSDHTPG-----WEMDVAAVALGA 236
WP_015404652 157 STFEEISSAVNIVTDLDL--EFALFQCTSMYPVPLTKVGLNVIEELRDRY-SCPIGYSDHTGS-----IYSGLAALAQSV 228
WP_126464012 163 ASFGEIEAAVDLIRSEGNd-QVMIHNCPTGYPARLESINLRMLPSLKQLF-ACPVAFSDHTPG-----WEMDVAAVALGA 235
1XUU_A       231 SILERHFTDRMDRPGPDIVCSMNPDTFKELKQGAHALKLARGGKK-DTIIAGEKPT-KDFAFASVVADKDIKKGELLSGD 308
ALP52643     233 RVLEKGLCADGSRNDQDVFHALPVSQLGQVIQKCRNIHSALGDAD-EAYMPPPQRP---AGRMGIIAQRDLTSGTVINLE 308
CUR50917     237 NLIEKHVTHDRSLKGEDYEAALDRDGIVKLVEWIRKIEGSLKNPHiKQLSKDELFY-RSVSMKRIVALTDIAKGETITAE 315
CUR50975     233 SMLEKTITTDKAIEHVEHFMSLELSELKRFVENIRAVEQAMGNPD----ILSTSRV-EETARRSLVAIRDIKKGEKITKQ 307
YP_094804    240 SILEKGVHLYPEDIDQDISHTMGIEQLAKTLETIYNCWQALGQPM-RDLEAPIKGVlGSSQRTCLVAKQKLQPGSLISLD 318
WP_083800256 251 VVLEKRLTLARNLPGHHHILSKEPGEFADYVRLIRQVQAAKGRHE-LNPSQKDLIE-RRKWFRHLVANQDIPQGTKLTPE 328
WP_013817853 219 KYLECHVVFDKRMFGPDSPASLTFAEFKQMVEGVRFLERAHANPV-NKEDIQGFEVlKRMFGKSLAVSRTLKMGETLVLN 297
WP_015229809 237 NLVEKTITLDRTTRSVEHIFSLEPSDMKQFVQTIRDLETAFGSTR-RLMSESERNK-RLATRRSCYYVHALQKGDLITEE 314
WP_015404652 229 DLLEVHVTLDKRSFGPDVPVSLTMEQLKQLVDARDAFKSIQENPVdKNLMASELMGmRGMFSKSVCVRKKLKKGTVLEES 308
WP_126464012 236 NLVEKTITEDRTIRSVEHIMSLEPDEMRRFVETIRSVETALGQTR-RILSDTEKRN-RIRVRRSVYLVEPVKAGQRLADA 313
1XUU_A       309 NLWVKRPG-NGdFSVNEYETLFGKVAACNIRKGAQIKktDIE 349
ALP52643     309 AVRFAFPT-LG-IAVEDWDKIDQARLKAPVAAGQPIEwsHVD 348
CUR50917     316 KITGKRSD-EG-LELDHRNSIIGRVAKIDIKKDDGITleKVV 355
CUR50975     308 DLDYKRPGnAG-ISVADGFKILDKRSMQDITAGTFLQwnMLD 348
YP_094804    319 NTTFAFPC-KG-VPTQYWDLVNGWELQNKVSIGEPIKwsDIK 358
WP_083800256 329 MLEGKRPE-PG-VSPEYLDFFVGRVTKRPLKYNEAISwdDI- 367
WP_013817853 298 DLESKKPAdRG-IPAELFRQVINKRLKHSIDAGDFLQwgDLS 338
WP_015229809 315 AIDYRRPG-YG-LSPKEVTKLIGNRVRQECPEGKQVEwtDLE 354
WP_015404652 309 LLTVKKPG-NG-IKPSETHKLLGCALVRDVTPDRLLRweDIE 348
WP_126464012 314 RVQFLRPG-FG-LAPDQYEAMLEYRFRVDLPAGMRLEagHLV 353
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